Mechanism of the reaction catalyzed by mandelate racemase: Structure and mechanistic properties of the D270N mutant

Biochemistry

Volumn 35, Issue 18, 1996, Pages 5662-5669

  Schafer, Susan L ^a,b   Barrett, William C ^a,b   Kallarakal, Abraham T ^a,b   Mitra, Bharati ^a,b   Kozarich, John W ^a,b,e   Gerlt, John A ^a,b   Clifton, James G ^c   Petsko, Gregory A ^c   Kenyon, George L ^d  

^a Bldg 142   (United States)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^c BRANDEIS UNIVERSITY   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATROLACTIC ACID; BROMIDE; MANDELATE RACEMASE; MANDELIC ACID; MUTANT PROTEIN; PLASMID DNA;

ARTICLE; ENANTIOMER; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME STRUCTURE; NONHUMAN; PH; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS PUTIDA; SITE DIRECTED MUTAGENESIS; STEREOSPECIFICITY; X RAY ANALYSIS;

BASE SEQUENCE; BINDING SITES; CATALYSIS; DNA, BACTERIAL; HYDROGEN-ION CONCENTRATION; KINETICS; MANDELIC ACIDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; MUTAGENESIS, SITE-DIRECTED; POINT MUTATION; PSEUDOMONAS PUTIDA; RACEMASES AND EPIMERASES; SOLVENTS; STEREOISOMERISM;

FELIS CATUS; MITRA; PSEUDOMONAS; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS PUTIDA;

EID: 0030002507     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi960174m     Document Type: Article

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