Modifications of diazepam binding inhibitor and peripheral benzodiazepine receptors in the lymphocytes of epileptic patients

Italian Journal of Neurological Sciences

Volumn 17, Issue 2, 1996, Pages 141-145

  Ferrarese, C ^a  

^a UNIVERSITY OF MILAN   (Italy)

Author keywords

benzodiazepine receptors; DBI; epilepsy; immunology

Indexed keywords

ANTICONVULSIVE AGENT; BENZODIAZEPINE RECEPTOR; CARBAMAZEPINE; CLONAZEPAM; DIAZEPAM BINDING INHIBITOR; ETHOSUXIMIDE; PHENOBARBITAL; PHENYTOIN; VALPROIC ACID;

ARTICLE; CONTROLLED STUDY; EPILEPSY; FEMALE; HUMAN; HUMAN CELL; IMMUNOREACTIVITY; LYMPHOCYTE; MAJOR CLINICAL STUDY; MALE; NEUROIMMUNOLOGY;

ADOLESCENT; CARBAMAZEPINE; CHILD; DIAZEPAM; EPILEPSY; FEMALE; HUMANS; LYMPHOCYTES; MALE; RECEPTORS, GABA-A;

EID: 0029994472     PISSN: 03920461     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02000845     Document Type: Article

References (31)

1. BENAVIDES J., GUILLOX F., ALLAM D.E. et al.: Opposite effects of an agonist, RO 5-4864, and an antagonist, PK 11185, of the peripheral type benzodiazepine binding sites on audiogenic seizures in DBA/2 J mice. Life, Sei. 34: 2613-2620, 1984.
2. BERKOVICH A., FERRARESE C., CAVALETTI G., ALHO H., MARZORATI C., BIANCHI G., GUIDOTTI A., COSTA E.: Topology of two DBI receptors in human lymphocytes. Life Sciences, 52: 1265-1277, 1993.
3. BESMAN M.J., YANAGIBASHI L., LEE T.D., KAWAMURA M., HALL P.P., SHIVELY J.E.: Identification of des-(GlyIle)-endozepine as an effector of corticotropin-dependent adrenal steroidogenesis: stimulation of cholesterol delivery is mediated by the peripheral benzodiazepine receptor. Proc. Natl. Acad. Sei. (U.S.A.), 86: 4897-4901, 1989.
4. BESSLER H., WEIZMAN R., GAVISH M., NOTTI L, DJALDETTI M.: Immunomodulatory effect of peripheral benzodiazepine receptor ligands on human mononuclear cells. J. Neuroimmunol., 38: 19-26, 1992.
5. BOYUM A.: Separation of white blood cells. Nature, 204: 793-828, 1964.
6. Commission on Classification and Terminology of the In-ternational League Against Epilepsy. Proposal for Revised Classification of Epilepsies and Epileptic Syndromes. Epilepsia 30(4): 389-399, 1989.
7. DOSCH H.M., JASON J., GELFAND E.W.: Transient antibod\ deficiency and abnormal T-suppressor cell induced byphenytoin. N. Engl. J. Med. 306: 406, 1982.
8. ëEG-OLOFSSON O., PRCHAL J.F., ANDERMANN F.: Abnormalities of T-lymphocyte subsets in epileptic patients. Acta Neurol'. Scand. 72: 140-144, 1985.
9. FERRARESE C, AEHO H., GUIDOTTI A., COSTA E.: Colocatiz.ation and co-release of GABA and putative allosteric modulators of GABA receptors. Neuropharmacology 26: 1011-1018, 1987.
10. FERRARESE C., APPOLLONIO I., BIANCHI G., FRIGO M., MARZORATI C., PECORA N., PEREGO M., PIERPAOEI C., FRATTOLA L.: Benzodiazepine receptors and diazepam binding inhibitor: a possible link between stress, anxiety and the immune system. Psychoneuroendocrinology 18: 3-22, 1993.
11. FERRARESE C., APPOLLONIO I., FRIGO M., PEREGO M., PIOLTI R., TRABUCCHI M., FRATTOLA L.: Decreased density of benzodiazepine receptors in lymphocytes of anxious patients: reversal after chronic diazepam treatment. Acta Psychiatr. Scand. 82: 169-173, 1990.
12. FERRARESE C., APPOLLONIO I., FRIGO M., PIOLTI R., TAMMA F., FRATTOLA L.: Distribution of a putative endogenous modulator of the GABAergic system in human brain. Neurology, 39: 443-445, 1989.
13. FERRARESE C., MARZORATI C.. PEREGO M., BIANCHI G., CAVARRETTA R., PIERPAOLI C.. MORETTI G., FRATTOLA L.: Effect of anticonvulsant drugs on peripheral benzodiazepine receptors of human lymphocytes. Neuropharmacology, 34: 427-431, 1995.
14. FERRARESE C., VACCARINO F., ALHO H., MELLSTROM B., COSTA E., GUIDOTTI A.: Subcellular location and neuronal release of diazepam binding inhibitor (DBI). J. Neurochem. 48:' 1093-1102, 1987.
15. FERRERO P., COSTA E., CONTI-TRONCONI B., GUIDOTTI A.: A diazepam binding inhibitor (DBI)-like neuropeptide is detected in human brain. Brain Res. 399: 136-142, 1986.
16. FILE S.E.: Pro- and anti-convulsant properties of PK 11195, a ligand for benzodiazepine binding sites: development of tolerance. Br. J. Pharmacol. 83: 471-476, 1984.
17. GILHUS N.E., MATRE R.: Carbamazepine effects on mononuclear blood cells in epileptic patients. Acta Neurol. Scand. 74: 181-185, 1986.
18. GUIDOTTI A., BERKOVITCH A., FERRARESE C., SANTI MR., COSTA E.: Neuronal- glial differential processing of DBI to yield ligands to central or peripheral benzodiazepine recognition sites. In: Sauvanet P., Langer S.Z., Morselli P.L. (Eds.)., Imidazopyridines in Sleep Disorders. Raven Press, New York, pp. 25-38, 1988.
19. JOHNSON E.W., DE LANEROLLE N.C., LIM J.H., SUNDERSAN S., SPENCER D.D., MATTSON R.H., ZOGHBI S.S.. BALDWIN R.M., HOFFER P.B., SEIBYL J.P., INNIS R.B.: Central and peripheral benzodiazepine receptors: opposite changes in human epileptogenic tissue. Neurology 42: 811-815, 1992.
20. LARKIN J.G., McKEE P.J., THOMPSON G.G., BRODIE M.J.: Peripheral benzodiazepine receptors in platelets of epileptic patients. Br. J. Clin. Pharmacol. 36(1): 71-74, 1993.
21. LlEDERMAN D.B., CSERNANSKY J.G., MOSES J.A. jr.: Neuroendocrinology and limbic epilepsy: relationship to psychopatholog\, seizure variables, and neuropsvchological function. Epilepsia 31: 270-274, 1990.
22. PACIFICI R., PARIS L., Di CARLO S., PICHINI S., ZUCCARO P.: Immunologie aspects of carbamazepine treatment in epileptic patients. Epilepsia 32: 122-127, 1991.
23. PAPADOPULOS V., GUARNERI P., KRUEGER K.E., GuiDOTTI A., COSTA E.: Pregnenolone biosynthesis in C6-2B glioma cell mitochondria: regulation by a mitochondrial diazepam binding inhibitor receptor. Proc. Natl. Acad. Sei. (USA), 89: 5113-5117, 1992.
24. ROCCA P., FERRERO P., GUALERZI A., ZANALDA E., MAINA G., BERGAMASCO B., RAVIZZA L.: Peripheral-type benzodiazepine receptors in anxiety disorders. Acta Psychiatr. Seand. 84: 537-544, 1991.
25. RUFF M.R., PERT C.B., WEBER R.J., WAHL L.M., WAHL S.M., PAUL S.M.: Benzodiazepine receptor-mediated chemotaxis of human monocvtes. Science 229: 1281-1283, 1985.
26. STRANDJORD R.E., JOHANNESSEN S.I., AARLI J.A.: Serum concentrations of immunoglobulins in patients with epilepsy treated with carbamazepine. Acta Neurol. Scand. 61: 260-263, 1980.
27. TAUPIN V., HERBELIN A., DESCAMPS-LATSCHA B., ZAVALA F.: Endogenous anxiogenic peptide, ODN-diazepam- binding inhibitor, and benzodiazepine s enhance the production of interleukin-1 and tumor necrosis factor by human monocvtes. Lymphokine and Cytokine Research 10: 7-13, 1991'.
28. VEZZANI A., SERAFINI R., STASI M.A., SAMANIN R., FERRARESE C.: Epileptogenic activity of two peptides derived from diazepam binding inhibitor after intrahippocampal injection in rats. Epilepsia 32(5): 597-603, 1991.
29. WEISS S.R.B., POST R.M.: Contingent tolerance to carbamazepine: a peripheral-type benzodiazepine mechanisms. Eur. J. Pharmacol. 193: 159-163, 1991.
30. WEISS S.R.B., POST R.M., PATEL J., MARANGOS P.J.: Differential mediation of the anticonvulsant effects of carbamazepine and diazepam. Life Sei. 36: 2413, 1985.
31. WEIZMAN A., TANNE Z., KARP L., MARTFELD Y., TYANO S., GAVISH M.: Carbamazepine up-regulates the binding of [3H]PK 11195 to platelets of epileptic patients. Eur. J. Pharmacol. 141: 471-474. 1987.