Properties and anti-HIV activity of nicked dumbbell oligonucleotides

Nucleosides and Nucleotides

Volumn 15, Issue 1-3, 1996, Pages 519-529

  Yamakawa, Hidefumi ^a,b   Hosono, Kazumi ^a   Ishibashi, Toshiaki ^a   Nakashima, Hideki ^c   Inagawa, Takafumi ^c   Yamamoto, Naoki ^d   Takai, Kazuyuki ^a   Takaku, Hiroshi ^a  

^a CHIBA INSTITUTE OF TECHNOLOGY   (Japan)

^b Rational Drug Design Laboratories   (Japan)

^c UNIVERSITY OF YAMANASHI   (Japan)

^d TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; ANTIVIRUS AGENT; OLIGONUCLEOTIDE;

ANTIVIRAL ACTIVITY; ARTICLE; DNA RNA HYBRIDIZATION; DRUG STABILITY; DRUG STRUCTURE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS;

EID: 0029988580     PISSN: 07328311     EISSN: None     Source Type: Journal    
DOI: 10.1080/07328319608002402     Document Type: Article

References (25)

1. Oligonucleotides, Antisense Inhibitions of Gene Expression (Cohen, J.S., ed.) (1989) Mac Millan Press.
2. Hélène, C. and Toulmé, J.J. (1990) Biochem.Biophys.Acta 1049, 99-125.
3. Prospects of Antisense Nucleic Acid Therapy of Cancer and AIDS (Wickstrom, E., ed.) (1991) Wiley-Liss Inc. New York.
4. Antisense RNA and DNA (Murray, J.A.H. ed.) (1992) Wiley-Liss Inc. New York.
5. Crooke, S.T. (1993) FASEB J. 7, 533-539.
6. Design and Targeted Reactions of oligonucleotide Derivatives (Knorre, D.G., Vlassov, V.V., Zarytova, V.F., Lebedev, A.V. and Fedorova, O.S. eds.) (1994) CRC Press, Boca Raton, Florida.
7. Carbohydrate Modifications in Antisense Research (Sanghvi, Y.S. and Dan Cook, P. eds.) (1994) ACS books, Washington, DC.
8. Agrawal, S. (1992) Trends in Biotechnology, 10, 152-158.
9. Tang, J.Y., Temsamani, J. and Agrawal, S. (1993) Nucleic Acids Res. 21, 2729-2735.
10. Zamecnik, P.C. and Stephenson, M.L. (1978) Proc.Natl.Acad.Sci. USA 75, 280-284.
11. Zamecnik, P.C., Goodchild, J., Taguchi, Y. and Sarin, P.S. (1986) Proc.Natl.Acad. Sci. USA 83, 4143-4146.
12. Matsukura, M., Shinozuka, K., Zon, G., Mitsuya, H., Reit, M., Cohen, J.C. and Broder, S. (1987) Proc.Natl.Acad.Sci. USA 84, 7706-7710.
13. Kim, S.-G., Suzuki, Y., Nakashima, H., Yamamoto, N. and Takaku, H. (1991) Biochem.Biophys.Res. Commun. 179, 1614-1619.
14. Miller, P.S., Agris, C.H., Aurelain, L., Blake, K.R., Murakami, A., Reddy, M.P., Spitz, S.A. and Ts'o, P.O.P. (1985) Biochimie 67, 769-776.
15. Lemaitre, M., Bayard, B. and Lebleu, B. (1987) Proc.Natl.Acad.Sci. USA 84, 648-652.
16. Smith, C.C., Aurelian, L., Reddy, M.P., Miller, P.S. and Ts'o, P.O.P. (1986) Proc. Natl.Acad.Sci. USA 83, 2787-2791.
17. Zerial, A., Thoug, N.T. and Hélène, C. (1987) Nucleic Acids Res. 15, 9909-9919.
18. Letiter, J.M.E., Agrawal, S., Palese, P. and Zamecnik, P.C. (1990) Proc.Natl.Acad. Sci. USA 87, 3430-3434.
19. Agrawal, S., Temsamani, J. and Tang, J.-Y. (1991) Proc.Natl.Acad.Sci. USA 88, 7595-7599.
20. Iverson, P. (1991) Anti-Cancer Drug Design 6, 531-538.
21. Sadaie, M.R., Rappaport, J., Benter, T., Josephs, S.F., Willis, R. and Wong-Staal, F. (1988) Proc.Natl.Acad.Sci. USA 85, 9224-9228.
22. Iyer, R.P., Phillips, L.R., Egan, W., Regan, J.B. and Beaucage, S.L. (1990) J.Org. Chem. 55, 4693-4698.
23. Newman, P.C., Nwosu, V.U., Williams, D.M., Cosstick, R., Seela, F. and Connolly, B.A. Biochemistry 29, 9891-9901.
24. Pauwels, R., Balzarini, J., Baba, M., Snoeck, R., Schols, D., Herdewijn, P., Desmyter, J. and De Clercq, E. (1988) J. Virol.Methods 20, 309-321.
25. Nakashima, H., Pauwels, R., Baba, M., Schols, D., Desmyter, J. and De Clercq, E. (1989) J. Virol.Methods 26, 319-330.