Immunohistochemical localization of the 11 β-hydroxysteroid dehydrogenase type II enzyme in human kidney and placenta

Journal of Clinical Endocrinology and Metabolism

Volumn 80, Issue 7, 1995, Pages 2203-2209

  Krozowski, Zygmunt ^a   MaGuire, Julie A ^a   Stein Oakley, Alicia N ^a   Dowling, John ^a   Smith, Robin E ^a   Andrews, Robert K ^a  

^a ALFRED HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE; ISOENZYME;

ARTICLE; ENZYME ACTIVITY; ENZYME LOCALIZATION; HORMONE RECEPTOR INTERACTION; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; KIDNEY; MOLECULAR CLONING; PLACENTA; PRIORITY JOURNAL; RECEPTOR AFFINITY; TISSUE DISTRIBUTION;

AMINO ACID SEQUENCE; ANTIBODIES; BLOTTING, WESTERN; CELL LINE; EPITHELIUM; FEMALE; HUMAN; HYDROXYSTEROID DEHYDROGENASES; IMMUNOHISTOCHEMISTRY; ISOENZYMES; KIDNEY; KIDNEY CORTEX; KIDNEY GLOMERULUS; KIDNEY TUBULES, COLLECTING; MICROSOMES; MOLECULAR SEQUENCE DATA; PEPTIDES; PLACENTA; PREGNANCY; RECOMBINANT PROTEINS; TRANSFECTION; TROPHOBLASTS;

EID: 0029026673     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jcem.80.7.7608280     Document Type: Article

References (41)

1. Edwards CR, Stewart PM, Burt D, et al. 1988 Localisation of 11 β-hydroxysteroid dehydrogenase: Tissue specific protector of the mineralocorticoid receptor. Lancet. 2:986-989.
2. Funder JW, Pearce PT, Smith R, Smith Al. 1988 Mineralocorticoid action: Target tissue specificity is enzyme, not receptor, mediated. Science. 242: 583-585.
3. Stewart PM, Wallace AM, Valentino R, Burt D, Shackleton CH, Edwards CRW. 1987 Mineralocorticoid activity of liquorice: 11-β-hydroxysteroid dehydrogenase comes of age. Lancet, ii: 821-824.
4. Ulick S, Levine SL, Gunczler P, et al. 1979 A syndrome of apparent mineralocorticoid excess associated with defects in the peripheral metabolism of cortisol. J Clin Endocrinol Metab. 49:757-763.
5. Tedde R, Pala A, Melis A, Ulick S. 1992 Evidence for cortisol as the mineralocorticoid in the syndrome of apparent mineralocorticoid excess. J Endocrinol Invest. 15:471-474.
6. Blasco MJ, Lopez-Bernal A, Turnbull AC. 1986 11-β-Hydrox-ysteroid dehydrogenase activity of the human placenta during pregnancy. Horm Metabol Res. 18:638-641.
7. Murphy BEP. 1981 Ontogeny of cortisol-cortisone interconversion in human tissues: A role for cortisone in human fetal development. J Steroid Biochem. 14:811-817.
8. Benediktsson R, Lindsay RS, Noble J, Seckl JR, Edwards C. 1993 Glucocorticoid exposure in utero: new model for adult hypertension. Lancet. 341:339-341.
9. Barker DJ, Bull AR, Osmond C, Simmonds SJ. 1990 Fetal and placental size and risk of hypertension in adult life. 1990 Br Med J. 301:259-262.
10. Duperrex H, Kenouch S, Gaeggeler HP, et al. 1993 Rat liver 11-β-hydroxysteroid dehydrogenase complementary deoxyribonucleic acid encodes oxoreductase activity in a mineralocorticoid-responsive toad bladder cell line. Endocrinology. 132:612-619.
11. Low SC, Chapman KE, Edwards C, Seckl JR. 1994 "Liver-type" 11 β-hydroxysteroid dehydrogenase cDN'A encodes reductase but not dehydrogenase activity in intact mammalian COS-7 cells. J Mol Endocrinol. 13:167-174.
12. Rusvai E, Naray-Fejes-Toth A. A new isoform of 11-β-hydrox-ysteroid dehydrogenase in aldosterone target cells. J Biol Chem. 268:10717-10720.
13. Brown RW, Chapman KE, Edwards C, Seckl JR. Human placental 11-β-hydroxysteroid dehydrogenase: evidence for and partial purification of a distinct NAD-dependent isoform. Endocrinology. 132:2614-2621.
14. Naray-Fejes-Toth A, Watlington CO, Fejes-Toth G. 1991 11-β-hydroxysteroid dehydrogenase activity in the renal target cells of aldosterone. Endocrinology. 129:17-21.
15. Mercer WR, Krozowski ZS. 1992 Localization of an 11 β hy-droxysteroid dehydrogenase activity to the distal nephron: evidence for the existence of two species of dehydrogenase in the rat kidney. Endocrinology. 130:540-543.
16. Albiston AL, Obeyesekere VR, Smith RE, Krozowski ZS. 1994 Cloning and tissue distribution of the human 11-β-hydroxy-steroid dehydrogenase tvpe II enzyme. Mol Cell Endocrinol. 105: R11-R17.
17. Lemer RA, Green N, Alexander H, Liu FT, Sutcliffe JG, Shinnick TM. 1981 Chemically synthesized peptides predicted from the nucleotide sequence of the hepatitis B virus genome elicit antibodies reactive with the native envelope protein of Dane particles. Proc Natl Acad Sci USA. 78:3403-3407.
18. Bemdt MC, Gregory C, Kabral A, Zola H, Fournier D, Castaldi PA. 1985 Purification and preliminary characterization of the glycoprotein ib complex in the human platelet membrane. Eur J Biochem. 151:637-649.
19. Bemdt MC, Chong BH, Bull HA, Zola H, Castaldi PA. 1985 Molecular characterization of quinine/quinidine drug-dependent antibody platelet interaction using monoclonal antibodies. Blood. 66: 1292-1301.
20. Heffeman M, Dennis JW. 1991 Polyoma and hamster papovavirus large T antigen-mediated replication of expression shuttle vectors in Chinese hamster ovary cells. Nucleic Acids Res. 19:85-92.
21. Stein-Oakley AN, Tzanidis A, Fuller PJ, Jablonski P, Thomson NM. 1994 Expression and distribution of epidermal growth factor in acute and chronic renal allograft rejection. Kidney Int. 46:1207-1215.
22. Albiston AL, Obeyesekere VR, Smith RE, Krozowski ZS. Cloning of the 11-β-HSD type II enzyme from human kidney. Endocr Res. In press.
23. Agarwal AK, Mune T, Monder C, White PC. 1994 NAD-dependent isoform of 11-β-hydroxysteroid dehydrogenase. J Biol Chem. 269: 25959-25962.
24. Krozowski ZS, Rundle SE, Wallace C, et al. 1989 Immunolocal-ization of renal mineralocorticoid receptors with an antiserum against a peptide deduced from the complementary deoxyribonucleic acid sequence. Endocrinology. 125:192-198.
25. Lombes M, Harman N, Oblin ME, et al. 1990 Immunohistochemical localization of renal mineralocorticoid receptor by using an anti-idiotvpic antibody that is an internal image of aldosterone. Proc Nat! Acad Sci USA. 87:1086-1088.
26. Fukushima K, Sasann H, Nagura H, Sasaki I, Matsuno S, Krozowski Z. 1991 Immunohistochemical localization of mineralocorticoid receptor in the human gut. Tohoku J Exp Med. 165:155-163.
27. Rundle SE, Funder JW, Lakshmi V, Monder C. 1989 The intrarenal localization of mineralocorticoid receptors and U-β-dehydroge-nase: Immunocytochemical studies. Endocrinology. 125:1700-1704.
28. Kenouch S, Alfaidy N, Bonvalet JP, Farman N. 1994 Expression of 11 β-Ohsd along the nephron of mammals and humans. Steroids. 59:100-104.
29. Naray-Fejes-Toth A, Watlington CO, Fejes-Toth G. 1991 11 β-hydroxysteroid dehydrogenase activity in the renal target cells of aldosterone. Endocrinology. 129:17-21.
30. Naray-Fejes-Toth A, Fejes-Toth G. 1990 Glucocorticoid receptors mediate mineralocorticoid-like effects in cultured collecting duct cells. Am J Physiol. 259:F672-F678.
31. Sasano H, Fukushima K, Sasaki I, Matsuno S, Nagura H, Krozowski ZS. 1992 Immunolocalization of mineralocorticoid receptor in human kidney, pancreas, salivary, mammary, and sweat glands: A light and electron microscopic immunohistochemical study. J Endocrinol. 132:305-310.
32. Stanton BA. 1986 Regulation by adrenal corticosteroids of sodium and potassium transport in loop of Henle and distal tubule of rat kidney. 1986 J Clin Invest. 78:1612-1620.
33. Work J, Jamison RL. 1987 Effect of adrenalectomy on transport in the rat medullary thick ascending limb. J Clin Invest. 80:1160-1164.
34. Funder JW, Pearce IT, Smith R, Campbell J. 1989 Vascular type I aldosterone binding sites are physiological mineralocorticoid receptors. Endocrinology. 125:2224-2226.
35. Sudhir K, Jennings GL, Esler MD, et al. 1989 Hydrocortisone-induced hypertension in humans: pressor responsiveness, and sympathetic function. Hypertension. 13:416-421.
36. Walker BR, Connacher A A, Webb DJ, Edwards C. 1992 Glucocorticoids and blood pressure: A role for the cortisol/cortisone shuttle in the control of vascular tone in man. Clin Sci. 83:171-178.
37. Krozowski ZS, Baker E, Obeyesekere V, Callen DF. Localization of the gene for human 11-β-hydroxysteroid dehydrogenase type 2 enzyme to chromosome 16qCytogenet Cell Genet. In press.
38. Buhler H, Perschel FH, Hierholzer K. 1991 Inhibition of rat renal 11-β-hydroxysteroid dehydrogenase by steroidal compounds and triterpenoids: structure function relationship. Biochim Biophys Acta. 1075:206-212.
39. Morris DJ, Semafuko WE, Latif SA, Vogel B, Grimes CA, Sheff MF. 1992 Detection of glycyrrhetinic acid-like factors (GALFs) in human urine. Hypertension. 20:356-360.
40. Smith MA, Thomford PJ, Mattison DR, Slikker WJ. 1988 Transport and metabolism of dexamethasone in the dually perfused human placenta. Reprod Toxicol. 2:37-43.
41. Althaus ZR, Bailey JR, Leakey JE, Slikker WJ. 1986 Transplacental metabolism of dexamethasone and cortisol in the late gestational age rhesus monkey (Macaca mulatta). Dev Pharmacol Ther. 9:332-349.