Cardiovascular disease in women: Implications of hormone replacement therapy

International Journal of Fertility and Menopausal Studies

Volumn 41, Issue 2, 1996, Pages 90-93

  Sarrel, Philip M ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

cardiovascular disease; coronary artery disease; estrogens; hormone replacement therapy (HRT); nitric oxide; progestins; vasoconstriction; vasodilatation

Indexed keywords

ESTROGEN; GESTAGEN; NITRIC OXIDE;

ADULT; ATHEROSCLEROSIS; CARDIOVASCULAR DISEASE; CONFERENCE PAPER; CORONARY ARTERY DISEASE; DRUG EFFECT; FEMALE; HEMODYNAMICS; HORMONE SUBSTITUTION; HUMAN; PRIORITY JOURNAL; VASOCONSTRICTION; VASODILATATION;

ARTERIOSCLEROSIS; CARDIOVASCULAR DISEASES; ESTROGEN REPLACEMENT THERAPY; FEMALE; HEMODYNAMIC PROCESSES; HUMANS; MIDDLE AGED; PROGESTINS; PROGNOSIS;

EID: 0029964703     PISSN: 10693130     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (20)

1. U.S. Department of Health and Human Services. Public Health Service. Centers for Disease Control. National Center for Health Statistics. Vital Statistics of the United States, 1986.
2. Bush TL, Barrett-Connor E, Cowan LD, et al: Cardiovascular mortality and non-contraceptive use of estrogen in women: Results from the Lipid Research Clinics Program Follow-up Study. Circulation 75:1102-1009, 1987.
3. Sarrel PM: Ovarian hormones and the circulation. Maturitas 12:287-298, 1990.
4. Crook D, Cust MP, Gangar KF, et al: Comparison of transdermal and oral estrogen-progestin in replacement therapy: effects on serum lipids and lipoproteins. Am J Obstet Gynecol 166:950-955, 1992.
5. Adams MR, Kaplan JR, Manuck SB, et al: Inhibition of coronary artery atherosclerosis by 17-beta estradiol in ovariectomized monkeys. Arteriosclerosis 10:1051- 1057, 1990.
6. Sullivan JM, Vander Zwaag R, Hughes JP, et al: Estrogen replacement therapy and coronary artery disease-effect on survival in postmenopausal women. Arch Intern Med 150:2557-2562, 1990.
7. Jiang C, Sarrel PM, Lindsay DC, et al: Endothelium-independent relaxation of rabbit coronary artery by 17 ß-oestradiol in vitro. Br f Pharmacol 104:1033-1037, 1991.
8. Collins P, Rosano GMC, Jiang C, et al: Cardiovascular protection by oestrogen-a calcium antagonist effect? Lancet 341:1264-1265, 1993.
9. Collins P, Rosano CMC, Sarrel PM, et al: Estradiol-17ß attenuates acetylcholine-induced coronary arterial constriction in women but not in men with coronary heart disease. Circulation 92:24-30, 1995.
10. Gilligan DM, Badar DM, Panza JA, et al: Acute vascular effects of estrogen in postmenopausal women. Circulation 90:786-791, 1994.
11. Pines A, Fisman EZ, Levo Y, et al: The effects of hormone replacement therapy in normal postmenopausal women: measurements of Doppler-derived parameters of aortic flow. Am J Obstet Gynecol 164:806-812, 1991.
12. Rosano CMC, Sarrel PM, Poole-Wilson P, et al: Beneficial effects of oestrogen in postmenopausal women. Lancet 342:133-135, 1993.
13. Magness RR, Rosenfeld CR: Local and systemic estradiol17ß: effects on uterine and systemic vasodilatation. Am J Physiol 256(Endocrinol Metab 19):E536-E542, 1989.
14. Caulin-Glaser TL, Sessa W, Sarrel PM, et al: Estradiol stimulates NO production via transcriptional and non-transcriptional pathways. Circulation 90:1-30, 1994.
15. Williams JK, Honore EK, Washburn SA, et al: Effects of hormone replacement therapy on reactivity of atherosclerotic arteries in cynomologous monkeys. J Am Coll Cardiol 24:1757-1761, 1994.
16. Owens JF, Stoney CM, Matthews KA: Menopausal status influences ambulatory blood pressure levels and blood pressure changes during mental stress. Circulation 88:27942802, 1993.
17. Kroneberg F, Cote LJ, Linki DM, et al: Menopausal hot flashes: thermoregulatory, cardiovascular and circulating catecholamine and LH changes. Maturitas 6:31-43, 1984.
18. Sarrel PM, Lindsay DC, Rosano CMC, et al: Angina and normal coronary arteries in women: gynecologic findings. Am J Obstet Gynecol 167:467-471, 1992.
19. Williams JK, Adams MR, Klopfenstein S: Estrogen modulates responses of atheroslcertoic arteries. Circulation 81:16801687, 1990.
20. Sarrel PM: How progestins compromise the cardioprotective effects of estrogens. Menopause 2:187-190, 1995.