The relationship of HsEg5 and the actin cytoskeleton to centrosome separation

Cell Motility and the Cytoskeleton

Volumn 35, Issue 4, 1996, Pages 298-308

  Whitehead, Clark M ^a   Winkfein, Robert J ^a   Rattner, J B ^a  

^a UNIVERSITY OF CALGARY   (Canada)

Author keywords

actin; centrosome separation; HsEg5; mitosis; spindle formation

Indexed keywords

ACTIN FILAMENT; ARTICLE; CENTROSOME; CYTOSKELETON; HELA CELL; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; METAPHASE; MITOSIS SPINDLE; PRIORITY JOURNAL; PROPHASE;

ACTINS; CENTROSOME; CYTOCHALASIN D; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HELA CELLS; HUMANS; KINESIN; METAPHASE; MICROSCOPY, ELECTRON; MICROTUBULES; MITOTIC SPINDLE APPARATUS; PROPHASE; XENOPUS PROTEINS;

EID: 0029956833     PISSN: 08861544     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0169(1996)35:4<298::AID-CM3>3.0.CO;2-3     Document Type: Article

References (19)

1. Ault, J.G., and Rieder, C.L. (1994): Centrosome and kinetochore movement during mitosis. Curr. Opin. Cell Biol. 6:41-49.
2. cdc2 regulates spindle association of Human Eg5, a kinesin-related motor protein essential for bipolar spindle formation in vivo. Cell 83:1159-1169.
3. Boleti, H., Karsenti, E., and Vernos, I. (1996): Xklp2, a novel Xenopus centrosomal kinesin-like protein required for centrosome separation during mitosis. Cell 84:49-59.
4. Karsenti, E., and Hyman, A.A. (1996): Morphogenetic properties of microtubules and mitotic spindle assembly. Cell 84:401-410.
5. Mack, G., and Rattner, J.B. (1993): Centrosome repositioning immediately following karyokinesis and prior to cytokinesis. Cell Motil. Cytoskeleton 26:239-247.
6. Pickett-Heaps, J.D., and Spurck, T.P. (1982): Studies on kinetochore function in mitosis. I. The effects of colchicine and cytochalasin on mitosis in the diatom Hantzschia amphioxys. Eur. J. Cell Biol. 28:77-82.
7. Rattner, J.B., and Berns, M.W. (1976): Distribution of microtubules during centriole separation in rat kangaroo (Potorous) cells. Cytobios 15:37-43.
8. Rattner, J.B., Martin, L., Waisman, D.M., Johnstone, S.A., and Fritzler, M.J. (1991): Autoantibodies to the centrosome (centriole) react with determinants present in the glycolytic enzyme enolase. J. Immunol. 146:2341-2344.
9. Rattner, J.B., Wang, T., Mack, G., Martin, L., and Fritzler, M.J. (1992): MSA-35: A protein identified by human autoantibodies that colocalizes with microtubules. Biochem. Cell Biol. 70: 1115-1122.
10. Sawin, K.E., and Mitchison, T.J. (1991): Mitotic spindle assembly by two different pathways in vivo. J. Cell Biol. 112:925-940.
11. Sluder, G., Miller, F.J., and Rieder, C.L. (1986): The reproduction of centrosomes: Nuclear versus cytoplasmic controls. J. Cell Biol. 103:1873-1881.
12. Theriot, J.A. (1995): The cell biology of infection by intracellular bacterial pathogens. In Spudich, J.A., Gerhart, J., McKnight, S.L., and Schekman, R. (eds.): "Annual Review of Cell and Development Biology." Annual Reviews Inc., Palo Alto, Calif., pp. 213-239.
13. Vaisberg, E.A., Koonce, M.P., and Mclntosh, J.R. (1993): Cytoplasmic dynein plays a role in mammalian mitotic spindle formation. J. Cell Biol. 123:849-858.
14. Walczak, C.E., and Mitchison, T.J. (1996): Kinesin-related proteins at mitotic spindle poles: Function and regulation. Cell 85:943-946.
15. Waters, J.C., Cole, R.W., and Rieder, C.L. (1993): The force-producing mechanism for centrosome separation during spindle formation in vertebrates is intrinsic to each aster. J. Cell Biol. 122:361-372.
16. Whitehead, C.M., Winkfein, R.J., Fritzler, M.J., and Rattner, J.B. (1996): The spindle kinesin-like protein HsEg5 is an autoantigen in systemic lupus erythematosus (SLE). Arthritis Rheum. (in press).
17. Zhang, D., and Nicklas, R.B. (1995): Chromosomes initiate spindle assembly upon experimental dissolution of the nuclear envelope in grasshopper spermatocytes. J. Cell Biol. 131:1125-1131.
18. Zhang, D., and Nicklas, R.B. (1996): The impact of chromosomes and centrosomes on spindle assembly as observed in living cells. J. Cell Biol. 129:1287-1300.
19. Zieve, G.W. (1984): Nocodazole and cytochalasin D induce tetraploidy in mammalian cells. Am. J. Physiol. 246 (Pt. 1):C154-156.