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Volumn 31, Issue 1-2, 1996, Pages 235-243

Models of initiation of replicative senescence by loss of telomeric DNA

Author keywords

DNA damage; replicative senescence; telomere

Indexed keywords

BINDING PROTEIN; DNA; DNA POLYMERASE; FREE RADICAL; NUCLEOPROTEIN; PROTEIN; PROTEIN P21; RNA;

EID: 0029936681     PISSN: 05315565     EISSN: None     Source Type: Journal    
DOI: 10.1016/0531-5565(95)02008-X     Document Type: Article
Times cited : (27)

References (48)
  • 1
    • 0020622392 scopus 로고
    • Three dimensional architecture of a polytene nucleus
    • AGARD, D.A. and SEDAT, J. W. Three dimensional architecture of a polytene nucleus. Nature 302, 676-681, 1983.
    • (1983) Nature , vol.302 , pp. 676-681
    • Agard, D.A.1    Sedat, J.W.2
  • 3
    • 0029145379 scopus 로고    scopus 로고
    • Evidence for a critical telomere length in senescent human fibroblasts
    • ALLSOPP, R.C. and HARLEY, C.B. Evidence for a critical telomere length in senescent human fibroblasts. Exp. Cell. Res 219, 130-136.
    • Exp. Cell. Res , vol.219 , pp. 130-136
    • Allsopp, R.C.1    Harley, C.B.2
  • 5
    • 0017166058 scopus 로고
    • Specific chromosome aberrations in senescent fibroblast cell lines derived from human embryos
    • BENN, P. Specific chromosome aberrations in senescent fibroblast cell lines derived from human embryos. Am. J. Hum. Genet. 28, 465-473, 1976.
    • (1976) Am. J. Hum. Genet. , vol.28 , pp. 465-473
    • Benn, P.1
  • 6
    • 0025731583 scopus 로고
    • The structure and function of telomeres
    • BLACKBURN, E.H. The structure and function of telomeres. Nature 350, 569-573, 1991.
    • (1991) Nature , vol.350 , pp. 569-573
    • Blackburn, E.H.1
  • 7
    • 0025222442 scopus 로고
    • RAP1 protein interacts with yeast telomeres in vivo: Overproduction alters telomere structure and decreases chromosome stability
    • CONRAD, M.N., WRIGHT, J.H., WOLF, A.J., and ZAKIAN, V.A. RAP1 protein interacts with yeast telomeres in vivo: Overproduction alters telomere structure and decreases chromosome stability. Cell 63, 739-750, 1990.
    • (1990) Cell , vol.63 , pp. 739-750
    • Conrad, M.N.1    Wright, J.H.2    Wolf, A.J.3    Zakian, V.A.4
  • 8
    • 0026523228 scopus 로고
    • Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity
    • COUNTER, C.M., AVILION, A.A., LE FEUVRE, C.E., STEWART, N.G., GREIDER, C.W., HARLEY, C.B., and BACCHETTI, S. Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. EMBO J. 11, 1921-1929, 1992.
    • (1992) EMBO J , vol.11 , pp. 1921-1929
    • Counter, C.M.1    Avilion, A.A.2    Le Feuvre, C.E.3    Stewart, N.G.4    Greider, C.W.5    Harley, C.B.6    Bacchetti, S.7
  • 10
    • 0028198679 scopus 로고
    • Stabilization of short telomeres and telomerase activity accompany immortalization of Epstein-Barr virus transformed human B lymphocytes
    • COUNTER, C.M., BOTELHO, F.M., WANG, P., and HARLEY, C.B. Stabilization of short telomeres and telomerase activity accompany immortalization of Epstein-Barr virus transformed human B lymphocytes. J. Virol. 68, 3410-3413, 1994b.
    • (1994) J. Virol. , vol.68 , pp. 3410-3413
    • Counter, C.M.1    Botelho, F.M.2    Wang, P.3    Harley, C.B.4
  • 12
    • 0026541384 scopus 로고
    • Human telomeres are attached to the nuclear matrix
    • DE LANGE, T. Human telomeres are attached to the nuclear matrix. EMBO J. 11, 717-724, 1992.
    • (1992) EMBO J , vol.11 , pp. 717-724
    • De Lange, T.1
  • 13
    • 0027970713 scopus 로고
    • DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts
    • di LEONARDO, A.I., LINKE, S.P., CLARKIN, K., and WAHL, G.M. DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts. Genes Dev. 8, 2540-2551, 1994.
    • (1994) Genes Dev. , vol.8 , pp. 2540-2551
    • Di Leonardo, A.I.1    Linke, S.P.2    Clarkin, K.3    Wahl, G.M.4
  • 14
    • 0028220204 scopus 로고
    • p53 dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest
    • DULIC, V., KAUFMANN, W.K., WILSON, S.J., TLSTY, T.D., LEES, E., HARPER, J.W., ELLEDGE, S.J., and REED, S.I. p53 dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest. Cell 76, 1013-1023, 1994.
    • (1994) Cell , vol.76 , pp. 1013-1023
    • Dulic, V.1    Kaufmann, W.K.2    Wilson, S.J.3    Tlsty, T.D.4    Lees, E.5    Harper, J.W.6    Elledge, S.J.7    Reed, S.I.8
  • 16
    • 0027529087 scopus 로고
    • Telomeres and the functional architecture of the nucleus
    • GILSON, E., LAROCHE, T., and GASSER, S. Telomeres and the functional architecture of the nucleus. Trends Cell Biol. 3, 128-134, 1993.
    • (1993) Trends Cell Biol. , vol.3 , pp. 128-134
    • Gilson, E.1    Laroche, T.2    Gasser, S.3
  • 17
    • 0022402513 scopus 로고
    • Identification of a specific telomere terminal transferase activity in Tet-rahymena extracts
    • GREIDER, C.W. and BLACKBURN, E.H. Identification of a specific telomere terminal transferase activity in Tet-rahymena extracts. Cell 43, 405-414, 1985.
    • (1985) Cell , vol.43 , pp. 405-414
    • Greider, C.W.1    Blackburn, E.H.2
  • 18
    • 0024978857 scopus 로고
    • A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis
    • GREIDER, C.W. and BLACKBURN, E.H. A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis. Nature 337, 331-337, 1989.
    • (1989) Nature , vol.337 , pp. 331-337
    • Greider, C.W.1    Blackburn, E.H.2
  • 19
    • 0025145238 scopus 로고
    • Replicative senescence: The human fibroblast comes of age
    • GOLDSTEIN, S. Replicative senescence: The human fibroblast comes of age. Science 249, 1129-1133, 1991.
    • (1991) Science , vol.249 , pp. 1129-1133
    • Goldstein, S.1
  • 20
    • 0025201982 scopus 로고
    • Position effect at S. cerevisiae telomeres: Reversible repression of Pol II transcription
    • GOTTSCHLING, D.E., APARICIO, O.M., BILLINGTON, B.L., and ZAKIAN, V.A. Position effect at S. cerevisiae telomeres: Reversible repression of Pol II transcription. Cell 63, 751-762, 1990.
    • (1990) Cell , vol.63 , pp. 751-762
    • Gottschling, D.E.1    Aparicio, O.M.2    Billington, B.L.3    Zakian, V.A.4
  • 21
    • 0025279931 scopus 로고
    • Telomeres shorten during aging of human fibroblasts
    • HARLEY, C.B., FUTCHER, A.B., and GREIDER, C.W. Telomeres shorten during aging of human fibroblasts. Nature 345, 458-460, 1990.
    • (1990) Nature , vol.345 , pp. 458-460
    • Harley, C.B.1    Futcher, A.B.2    Greider, C.W.3
  • 22
    • 0025787643 scopus 로고
    • Telomere loss: Mitotic clock or genetic time bomb?
    • HARLEY, C.B. Telomere loss: Mitotic clock or genetic time bomb? Mutat. Res. 256, 271-282, 1991.
    • (1991) Mutat. Res. , vol.256 , pp. 271-282
    • Harley, C.B.1
  • 23
    • 0027496935 scopus 로고
    • The p21 cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
    • HARPER, J.W., ADAMI, G.R., WEI, N., KEYOMARSI, K., and ELLEDGE, S. The p21 cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell 75, 805-816, 1993.
    • (1993) Cell , vol.75 , pp. 805-816
    • Harper, J.W.1    Adami, G.R.2    Wei, N.3    Keyomarsi, K.4    Elledge, S.5
  • 24
    • 0344622606 scopus 로고
    • The serial cultivation of human diploid strains
    • HAYFLICK, L. and MOORHEAD, P. The serial cultivation of human diploid strains Exp. Cell Res. 25, 585-621, 1961.
    • (1961) Exp. Cell Res. , vol.25 , pp. 585-621
    • Hayflick, L.1    Moorhead, P.2
  • 25
    • 0024573115 scopus 로고
    • An overhanging 3′ terminus is a conserved feature of telomeres
    • HENDERSON, E.R. and BLACKBURN, E.H. An overhanging 3′ terminus is a conserved feature of telomeres. Mol. Cell. Biol. 9, 345-348, 1989.
    • (1989) Mol. Cell. Biol. , vol.9 , pp. 345-348
    • Henderson, E.R.1    Blackburn, E.H.2
  • 27
    • 0028140264 scopus 로고
    • Restoration of telomeres in human papillomavirus-immortalized human anogenital epithelial cells
    • KLINGELHUTZ, A.J., BARBER, S.A., SMITH, P.P., DYER, K., and MC DOUGALL, J.K. Restoration of telomeres in human papillomavirus-immortalized human anogenital epithelial cells. Mol. Cell. Biol. 14, 961-969, 1994.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 961-969
    • Klingelhutz, A.J.1    Barber, S.A.2    Smith, P.P.3    Dyer, K.4    Mc Dougall, J.K.5
  • 28
    • 0019568388 scopus 로고
    • All gene-sized DNA molecules in 4 species of hypotrichs have the same terminal sequence and an unusual 3′ terminus
    • KLOBUTCHER, L.A., SWANTON, M.T., DONINI, P., and PRESCOTT, D.M. All gene-sized DNA molecules in 4 species of hypotrichs have the same terminal sequence and an unusual 3′ terminus. Proc. Natl. Acad. Sci. USA 78, 3015-3019, 1981.
    • (1981) Proc. Natl. Acad. Sci. USA , vol.78 , pp. 3015-3019
    • Klobutcher, L.A.1    Swanton, M.T.2    Donini, P.3    Prescott, D.M.4
  • 30
    • 0001294157 scopus 로고
    • The stability of broken ends of chromosomes in Zea mays
    • MC CLINTOCK, B. The stability of broken ends of chromosomes in Zea mays. Genetics 26, 234-282, 1941.
    • (1941) Genetics , vol.26 , pp. 234-282
    • Mc Clintock, B.1
  • 31
    • 0024325562 scopus 로고
    • The human telomere terminal transferase is a ribonucleoprotein that synthesizes TTAGGG repeats
    • MORIN, G. The human telomere terminal transferase is a ribonucleoprotein that synthesizes TTAGGG repeats. Cell 59, 521-529, 1990.
    • (1990) Cell , vol.59 , pp. 521-529
    • Morin, G.1
  • 32
    • 0000049842 scopus 로고
    • The remaking of chromosomes
    • MUELLER, H.J. The remaking of chromosomes. Collecting Net. 13, 181-198, 1938.
    • (1938) Collecting Net. , vol.13 , pp. 181-198
    • Mueller, H.J.1
  • 33
    • 0028342664 scopus 로고
    • Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen
    • NODA, A., NING, Y., VENABLE, S.F., PEREIRA-SMITH, O.M., and SMITH, J.R. Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen. Exp. Cell Res. 211, 90-98, 1994.
    • (1994) Exp. Cell Res. , vol.211 , pp. 90-98
    • Noda, A.1    Ning, Y.2    Venable, S.F.3    Pereira-Smith, O.M.4    Smith, J.R.5
  • 34
    • 0001029496 scopus 로고
    • A theory of marginotomy
    • OLOVNIKOV, A.M. A theory of marginotomy. Doklady Biochem. 201, 394-397, 1971.
    • (1971) Doklady Biochem. , vol.201 , pp. 394-397
    • Olovnikov, A.M.1
  • 35
    • 0027421043 scopus 로고
    • Loss of a yeast telomere: Arrest, recovery, and chromosome loss
    • SANDELL, L.L. and ZAKIAN, V. Loss of a yeast telomere: Arrest, recovery, and chromosome loss. Cell 75, 729-739, 1993.
    • (1993) Cell , vol.75 , pp. 729-739
    • Sandell, L.L.1    Zakian, V.2
  • 36
    • 0028171292 scopus 로고
    • G1 phase progression: Cycling on cue
    • SHERR, C.J. G1 phase progression: Cycling on cue. Cell 79, 551-555, 1994.
    • (1994) Cell , vol.79 , pp. 551-555
    • Sherr, C.J.1
  • 39
    • 0024453646 scopus 로고
    • Three-dimensional analysis of the organization of human chromosome domains in human and human-hamster hybrid interphase nuclei
    • VAN DEKKEN, H., PINKEL, D., MULLIKIN, J., TRASK, B., VAN DEN ENGH, G., and GRAY, J. Three-dimensional analysis of the organization of human chromosome domains in human and human-hamster hybrid interphase nuclei. J. Cell Sci. 94, 299-306, 1989.
    • (1989) J. Cell Sci. , vol.94 , pp. 299-306
    • Van Dekken, H.1    Pinkel, D.2    Mullikin, J.3    Trask, B.4    Van Den Engh, G.5    Gray, J.6
  • 42
    • 0029924534 scopus 로고    scopus 로고
    • From telomere loss to p53 activation and induction of a DNA-damage pathway at senescence: The telomere loss/DNA damage model of cell aging
    • VAZIRI, H. From telomere loss to p53 activation and induction of a DNA-damage pathway at senescence: The telomere loss/DNA damage model of cell aging. Exp. Geront. 31 295-302, 1996.
    • (1996) Exp. Geront. , vol.31 , pp. 295-302
    • Vaziri, H.1
  • 43
    • 0015515155 scopus 로고
    • Origin of concatameric T4 DNA
    • WATSON, J. D. Origin of concatameric T4 DNA. Nature New Biol. 239, 197-201, 1972.
    • (1972) Nature New Biol. , vol.239 , pp. 197-201
    • Watson, J.D.1
  • 44
    • 0024366596 scopus 로고
    • Reversible cellular senescence: Implications for immortalization of normal human diploid fibroblasts
    • WRIGHT, W.E., PEREIRA-SMITH, O.M., and SHAY, J.W. Reversible cellular senescence: Implications for immortalization of normal human diploid fibroblasts. Mol. Cell. Biol. 9, 3088-3092, 1989.
    • (1989) Mol. Cell. Biol. , vol.9 , pp. 3088-3092
    • Wright, W.E.1    Pereira-Smith, O.M.2    Shay, J.W.3
  • 45
    • 0026682717 scopus 로고
    • Telomere positional effects and the regulation of cellular senescence
    • WRIGHT, W.E. and SHAY, J.W. Telomere positional effects and the regulation of cellular senescence. Trends Genet. 8, 193-197, 1992.
    • (1992) Trends Genet. , vol.8 , pp. 193-197
    • Wright, W.E.1    Shay, J.W.2
  • 46
    • 0025279059 scopus 로고
    • In vivo alteration of telomere sequences and senescence caused by mutated telomerase RNAs
    • YU, G.-L., BRADLEY, J.D., ATTARDI, L.D., and BLACKBURN, E.H. In vivo alteration of telomere sequences and senescence caused by mutated telomerase RNAs. Nature 344, 126-132, 1990.
    • (1990) Nature , vol.344 , pp. 126-132
    • Yu, G.-L.1    Bradley, J.D.2    Attardi, L.D.3    Blackburn, E.H.4
  • 47
    • 0024788528 scopus 로고
    • The structure and function of telomeres
    • ZAKIAN, V. The structure and function of telomeres. Annu. Rev. Genet. 23, 579-604, 1989.
    • (1989) Annu. Rev. Genet. , vol.23 , pp. 579-604
    • Zakian, V.1
  • 48
    • 0026668731 scopus 로고
    • A mammalian factor that binds telomeric TTAGGG repeats in vitro
    • ZHONG, Z., SHIUE, L., KAPLAN, S., and DE LANGE, T. A mammalian factor that binds telomeric TTAGGG repeats in vitro. Mol. Cell. Biol. 12, 4834-4843, 1992.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 4834-4843
    • Zhong, Z.1    Shiue, L.2    Kaplan, S.3    De Lange, T.4


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