-
1
-
-
0020622392
-
Three dimensional architecture of a polytene nucleus
-
AGARD, D.A. and SEDAT, J. W. Three dimensional architecture of a polytene nucleus. Nature 302, 676-681, 1983.
-
(1983)
Nature
, vol.302
, pp. 676-681
-
-
Agard, D.A.1
Sedat, J.W.2
-
2
-
-
0026460896
-
Telomere length predicts replicative capacity in human fibroblasts
-
ALLSOPP, R.C., VAZIRI, H., PATTERSON, C., GOLDSTEIN, S., YOUNGLAI, E.V., FUTCHER, A.B., GREIDER, C.W., and HARLEY, C.B. Telomere length predicts replicative capacity in human fibroblasts. Proc. Natl. Acad. Sci. USA 89, 10114-10118, 1992.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 10114-10118
-
-
Allsopp, R.C.1
Vaziri, H.2
Patterson, C.3
Goldstein, S.4
Younglai, E.V.5
Futcher, A.B.6
Greider, C.W.7
Harley, C.B.8
-
3
-
-
0029145379
-
Evidence for a critical telomere length in senescent human fibroblasts
-
ALLSOPP, R.C. and HARLEY, C.B. Evidence for a critical telomere length in senescent human fibroblasts. Exp. Cell. Res 219, 130-136.
-
Exp. Cell. Res
, vol.219
, pp. 130-136
-
-
Allsopp, R.C.1
Harley, C.B.2
-
4
-
-
0029111404
-
Increased activity of p53 in senescing fibroblasts
-
ATADJA, P., WONG, H., GARKAVTSEV, I., VEILLETTE, C., and RIABOWOL, K. Increased activity of p53 in senescing fibroblasts. Proc. Natl. Acad. Sci. USA 92, 8348-8352, 1995.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 8348-8352
-
-
Atadja, P.1
Wong, H.2
Garkavtsev, I.3
Veillette, C.4
Riabowol, K.5
-
5
-
-
0017166058
-
Specific chromosome aberrations in senescent fibroblast cell lines derived from human embryos
-
BENN, P. Specific chromosome aberrations in senescent fibroblast cell lines derived from human embryos. Am. J. Hum. Genet. 28, 465-473, 1976.
-
(1976)
Am. J. Hum. Genet.
, vol.28
, pp. 465-473
-
-
Benn, P.1
-
6
-
-
0025731583
-
The structure and function of telomeres
-
BLACKBURN, E.H. The structure and function of telomeres. Nature 350, 569-573, 1991.
-
(1991)
Nature
, vol.350
, pp. 569-573
-
-
Blackburn, E.H.1
-
7
-
-
0025222442
-
RAP1 protein interacts with yeast telomeres in vivo: Overproduction alters telomere structure and decreases chromosome stability
-
CONRAD, M.N., WRIGHT, J.H., WOLF, A.J., and ZAKIAN, V.A. RAP1 protein interacts with yeast telomeres in vivo: Overproduction alters telomere structure and decreases chromosome stability. Cell 63, 739-750, 1990.
-
(1990)
Cell
, vol.63
, pp. 739-750
-
-
Conrad, M.N.1
Wright, J.H.2
Wolf, A.J.3
Zakian, V.A.4
-
8
-
-
0026523228
-
Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity
-
COUNTER, C.M., AVILION, A.A., LE FEUVRE, C.E., STEWART, N.G., GREIDER, C.W., HARLEY, C.B., and BACCHETTI, S. Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. EMBO J. 11, 1921-1929, 1992.
-
(1992)
EMBO J
, vol.11
, pp. 1921-1929
-
-
Counter, C.M.1
Avilion, A.A.2
Le Feuvre, C.E.3
Stewart, N.G.4
Greider, C.W.5
Harley, C.B.6
Bacchetti, S.7
-
9
-
-
0028262113
-
Telomerase activity in human ovarian carcinoma
-
COUNTER, C.M., HIRTE, H., BACCHETTI, S., and HARLEY, C.B. Telomerase activity in human ovarian carcinoma. Proc. Natl. Acad. Sci. USA 91, 2900-2904, 1994a.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 2900-2904
-
-
Counter, C.M.1
Hirte, H.2
Bacchetti, S.3
Harley, C.B.4
-
10
-
-
0028198679
-
Stabilization of short telomeres and telomerase activity accompany immortalization of Epstein-Barr virus transformed human B lymphocytes
-
COUNTER, C.M., BOTELHO, F.M., WANG, P., and HARLEY, C.B. Stabilization of short telomeres and telomerase activity accompany immortalization of Epstein-Barr virus transformed human B lymphocytes. J. Virol. 68, 3410-3413, 1994b.
-
(1994)
J. Virol.
, vol.68
, pp. 3410-3413
-
-
Counter, C.M.1
Botelho, F.M.2
Wang, P.3
Harley, C.B.4
-
11
-
-
0025115349
-
Structure and variability of human chromosome ends
-
DE LANGE, T., SHIUE, L., MYERS, R. M., COX, D. R., NAYLOR, S. L., KILLERY, A. M., and VARMUS, H. E. Structure and variability of human chromosome ends. Mol. Cell Biol. 10, 518-527, 1990.
-
(1990)
Mol. Cell Biol.
, vol.10
, pp. 518-527
-
-
De Lange, T.1
Shiue, L.2
Myers, R.M.3
Cox, D.R.4
Naylor, S.L.5
Killery, A.M.6
Varmus, H.E.7
-
12
-
-
0026541384
-
Human telomeres are attached to the nuclear matrix
-
DE LANGE, T. Human telomeres are attached to the nuclear matrix. EMBO J. 11, 717-724, 1992.
-
(1992)
EMBO J
, vol.11
, pp. 717-724
-
-
De Lange, T.1
-
13
-
-
0027970713
-
DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts
-
di LEONARDO, A.I., LINKE, S.P., CLARKIN, K., and WAHL, G.M. DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts. Genes Dev. 8, 2540-2551, 1994.
-
(1994)
Genes Dev.
, vol.8
, pp. 2540-2551
-
-
Di Leonardo, A.I.1
Linke, S.P.2
Clarkin, K.3
Wahl, G.M.4
-
14
-
-
0028220204
-
p53 dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest
-
DULIC, V., KAUFMANN, W.K., WILSON, S.J., TLSTY, T.D., LEES, E., HARPER, J.W., ELLEDGE, S.J., and REED, S.I. p53 dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest. Cell 76, 1013-1023, 1994.
-
(1994)
Cell
, vol.76
, pp. 1013-1023
-
-
Dulic, V.1
Kaufmann, W.K.2
Wilson, S.J.3
Tlsty, T.D.4
Lees, E.5
Harper, J.W.6
Elledge, S.J.7
Reed, S.I.8
-
15
-
-
0027359827
-
WAF1, a potent mediator of p53 tumor suppression
-
EL-DEIRY, W.S., TOKINO, T., VELCULESCU, V.E., LEVY, D.B., PARSONS, R., TRENT, J.M., LIN, D., MERCER, E., KINZLER, K.W., and VOGELSTEIN, B. WAF1, a potent mediator of p53 tumor suppression. Cell 75, 817-825, 1993.
-
(1993)
Cell
, vol.75
, pp. 817-825
-
-
El-Deiry, W.S.1
Tokino, T.2
Velculescu, V.E.3
Levy, D.B.4
Parsons, R.5
Trent, J.M.6
Lin, D.7
Mercer, E.8
Kinzler, K.W.9
Vogelstein, B.10
-
16
-
-
0027529087
-
Telomeres and the functional architecture of the nucleus
-
GILSON, E., LAROCHE, T., and GASSER, S. Telomeres and the functional architecture of the nucleus. Trends Cell Biol. 3, 128-134, 1993.
-
(1993)
Trends Cell Biol.
, vol.3
, pp. 128-134
-
-
Gilson, E.1
Laroche, T.2
Gasser, S.3
-
17
-
-
0022402513
-
Identification of a specific telomere terminal transferase activity in Tet-rahymena extracts
-
GREIDER, C.W. and BLACKBURN, E.H. Identification of a specific telomere terminal transferase activity in Tet-rahymena extracts. Cell 43, 405-414, 1985.
-
(1985)
Cell
, vol.43
, pp. 405-414
-
-
Greider, C.W.1
Blackburn, E.H.2
-
18
-
-
0024978857
-
A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis
-
GREIDER, C.W. and BLACKBURN, E.H. A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis. Nature 337, 331-337, 1989.
-
(1989)
Nature
, vol.337
, pp. 331-337
-
-
Greider, C.W.1
Blackburn, E.H.2
-
19
-
-
0025145238
-
Replicative senescence: The human fibroblast comes of age
-
GOLDSTEIN, S. Replicative senescence: The human fibroblast comes of age. Science 249, 1129-1133, 1991.
-
(1991)
Science
, vol.249
, pp. 1129-1133
-
-
Goldstein, S.1
-
20
-
-
0025201982
-
Position effect at S. cerevisiae telomeres: Reversible repression of Pol II transcription
-
GOTTSCHLING, D.E., APARICIO, O.M., BILLINGTON, B.L., and ZAKIAN, V.A. Position effect at S. cerevisiae telomeres: Reversible repression of Pol II transcription. Cell 63, 751-762, 1990.
-
(1990)
Cell
, vol.63
, pp. 751-762
-
-
Gottschling, D.E.1
Aparicio, O.M.2
Billington, B.L.3
Zakian, V.A.4
-
21
-
-
0025279931
-
Telomeres shorten during aging of human fibroblasts
-
HARLEY, C.B., FUTCHER, A.B., and GREIDER, C.W. Telomeres shorten during aging of human fibroblasts. Nature 345, 458-460, 1990.
-
(1990)
Nature
, vol.345
, pp. 458-460
-
-
Harley, C.B.1
Futcher, A.B.2
Greider, C.W.3
-
22
-
-
0025787643
-
Telomere loss: Mitotic clock or genetic time bomb?
-
HARLEY, C.B. Telomere loss: Mitotic clock or genetic time bomb? Mutat. Res. 256, 271-282, 1991.
-
(1991)
Mutat. Res.
, vol.256
, pp. 271-282
-
-
Harley, C.B.1
-
23
-
-
0027496935
-
The p21 cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
-
HARPER, J.W., ADAMI, G.R., WEI, N., KEYOMARSI, K., and ELLEDGE, S. The p21 cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell 75, 805-816, 1993.
-
(1993)
Cell
, vol.75
, pp. 805-816
-
-
Harper, J.W.1
Adami, G.R.2
Wei, N.3
Keyomarsi, K.4
Elledge, S.5
-
24
-
-
0344622606
-
The serial cultivation of human diploid strains
-
HAYFLICK, L. and MOORHEAD, P. The serial cultivation of human diploid strains Exp. Cell Res. 25, 585-621, 1961.
-
(1961)
Exp. Cell Res.
, vol.25
, pp. 585-621
-
-
Hayflick, L.1
Moorhead, P.2
-
25
-
-
0024573115
-
An overhanging 3′ terminus is a conserved feature of telomeres
-
HENDERSON, E.R. and BLACKBURN, E.H. An overhanging 3′ terminus is a conserved feature of telomeres. Mol. Cell. Biol. 9, 345-348, 1989.
-
(1989)
Mol. Cell. Biol.
, vol.9
, pp. 345-348
-
-
Henderson, E.R.1
Blackburn, E.H.2
-
26
-
-
0028564951
-
Specific association of telomerase activity with immortal cells and cancer
-
KIM, N.W., PIATYSZEK, M.A., PROWSE, K.R., HARLEY, C.B., WEST, M.D., HO, P.L., COVIELLO, G.M., WRIGHT, W.E. WEINRICH, S.L., and SHAY, J.W. Specific association of telomerase activity with immortal cells and cancer. Science 266, 2011-2014, 1994.
-
(1994)
Science
, vol.266
, pp. 2011-2014
-
-
Kim, N.W.1
Piatyszek, M.A.2
Prowse, K.R.3
Harley, C.B.4
West, M.D.5
Ho, P.L.6
Coviello, G.M.7
Wright, W.E.8
Weinrich, S.L.9
Shay, J.W.10
-
27
-
-
0028140264
-
Restoration of telomeres in human papillomavirus-immortalized human anogenital epithelial cells
-
KLINGELHUTZ, A.J., BARBER, S.A., SMITH, P.P., DYER, K., and MC DOUGALL, J.K. Restoration of telomeres in human papillomavirus-immortalized human anogenital epithelial cells. Mol. Cell. Biol. 14, 961-969, 1994.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 961-969
-
-
Klingelhutz, A.J.1
Barber, S.A.2
Smith, P.P.3
Dyer, K.4
Mc Dougall, J.K.5
-
28
-
-
0019568388
-
All gene-sized DNA molecules in 4 species of hypotrichs have the same terminal sequence and an unusual 3′ terminus
-
KLOBUTCHER, L.A., SWANTON, M.T., DONINI, P., and PRESCOTT, D.M. All gene-sized DNA molecules in 4 species of hypotrichs have the same terminal sequence and an unusual 3′ terminus. Proc. Natl. Acad. Sci. USA 78, 3015-3019, 1981.
-
(1981)
Proc. Natl. Acad. Sci. USA
, vol.78
, pp. 3015-3019
-
-
Klobutcher, L.A.1
Swanton, M.T.2
Donini, P.3
Prescott, D.M.4
-
29
-
-
0026735646
-
Telomere end-replication problem and cell senescence
-
LEVY, M.L., ALLSOPP, R.C., FUTCHER, A.B., GREIDER, C.W., and HARLEY, C.B. Telomere end-replication problem and cell senescence. J. Mol. Biol. 225, 951-960, 1992.
-
(1992)
J. Mol. Biol.
, vol.225
, pp. 951-960
-
-
Levy, M.L.1
Allsopp, R.C.2
Futcher, A.B.3
Greider, C.W.4
Harley, C.B.5
-
30
-
-
0001294157
-
The stability of broken ends of chromosomes in Zea mays
-
MC CLINTOCK, B. The stability of broken ends of chromosomes in Zea mays. Genetics 26, 234-282, 1941.
-
(1941)
Genetics
, vol.26
, pp. 234-282
-
-
Mc Clintock, B.1
-
31
-
-
0024325562
-
The human telomere terminal transferase is a ribonucleoprotein that synthesizes TTAGGG repeats
-
MORIN, G. The human telomere terminal transferase is a ribonucleoprotein that synthesizes TTAGGG repeats. Cell 59, 521-529, 1990.
-
(1990)
Cell
, vol.59
, pp. 521-529
-
-
Morin, G.1
-
32
-
-
0000049842
-
The remaking of chromosomes
-
MUELLER, H.J. The remaking of chromosomes. Collecting Net. 13, 181-198, 1938.
-
(1938)
Collecting Net.
, vol.13
, pp. 181-198
-
-
Mueller, H.J.1
-
33
-
-
0028342664
-
Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen
-
NODA, A., NING, Y., VENABLE, S.F., PEREIRA-SMITH, O.M., and SMITH, J.R. Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen. Exp. Cell Res. 211, 90-98, 1994.
-
(1994)
Exp. Cell Res.
, vol.211
, pp. 90-98
-
-
Noda, A.1
Ning, Y.2
Venable, S.F.3
Pereira-Smith, O.M.4
Smith, J.R.5
-
34
-
-
0001029496
-
A theory of marginotomy
-
OLOVNIKOV, A.M. A theory of marginotomy. Doklady Biochem. 201, 394-397, 1971.
-
(1971)
Doklady Biochem.
, vol.201
, pp. 394-397
-
-
Olovnikov, A.M.1
-
35
-
-
0027421043
-
Loss of a yeast telomere: Arrest, recovery, and chromosome loss
-
SANDELL, L.L. and ZAKIAN, V. Loss of a yeast telomere: Arrest, recovery, and chromosome loss. Cell 75, 729-739, 1993.
-
(1993)
Cell
, vol.75
, pp. 729-739
-
-
Sandell, L.L.1
Zakian, V.2
-
36
-
-
0028171292
-
G1 phase progression: Cycling on cue
-
SHERR, C.J. G1 phase progression: Cycling on cue. Cell 79, 551-555, 1994.
-
(1994)
Cell
, vol.79
, pp. 551-555
-
-
Sherr, C.J.1
-
37
-
-
0000133469
-
Defining cellular senescence in IMR-90 cells: A How cytometric analysis
-
SHERWOOD, S.W., RUSH, D., ELLSWORTH, J.L., and SCHIMKE, R.T. Defining cellular senescence in IMR-90 cells: A How cytometric analysis. Proc. Natl. Acad. Sci. USA 85, 9086-9090, 1989.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 9086-9090
-
-
Sherwood, S.W.1
Rush, D.2
Ellsworth, J.L.3
Schimke, R.T.4
-
38
-
-
0027949202
-
Oxidative damage and mitochondrial decay in aging
-
SHIGENAGA, M.K., HAGEN, T.M., and AMES, B.N. Oxidative damage and mitochondrial decay in aging. Proc. Natl. Acad. Sci. USA 91, 10771-10778, 1994.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 10771-10778
-
-
Shigenaga, M.K.1
Hagen, T.M.2
Ames, B.N.3
-
39
-
-
0024453646
-
Three-dimensional analysis of the organization of human chromosome domains in human and human-hamster hybrid interphase nuclei
-
VAN DEKKEN, H., PINKEL, D., MULLIKIN, J., TRASK, B., VAN DEN ENGH, G., and GRAY, J. Three-dimensional analysis of the organization of human chromosome domains in human and human-hamster hybrid interphase nuclei. J. Cell Sci. 94, 299-306, 1989.
-
(1989)
J. Cell Sci.
, vol.94
, pp. 299-306
-
-
Van Dekken, H.1
Pinkel, D.2
Mullikin, J.3
Trask, B.4
Van Den Engh, G.5
Gray, J.6
-
40
-
-
0027486732
-
Loss of telomeric DNA during aging of normal and trisomy 21 human lymphocytes
-
VAZIRI, H., SCHACHTER, F., UCHIDA, I., WEI, L., ZHU, X., EFFROS, R., COHEN, D., and HARLEY, C.B. Loss of telomeric DNA during aging of normal and trisomy 21 human lymphocytes. Am. J. Hum. Genet. 52, 661-667, 1993.
-
(1993)
Am. J. Hum. Genet.
, vol.52
, pp. 661-667
-
-
Vaziri, H.1
Schachter, F.2
Uchida, I.3
Wei, L.4
Zhu, X.5
Effros, R.6
Cohen, D.7
Harley, C.B.8
-
41
-
-
0028077099
-
Evidence for a mitotic clock in human hematopoietic stem cells: Loss of telomeric DNA with age
-
VAZIRI, H., DRAGOWSKA, W., ALLSOPP, R.C., THOMAS, T.E., HARLEY, C.B., and LANSDORP, P.L. Evidence for a mitotic clock in human hematopoietic stem cells: Loss of telomeric DNA with age. Proc. Natl. Acad. Sci. USA 91, 9857-9860, 1994.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 9857-9860
-
-
Vaziri, H.1
Dragowska, W.2
Allsopp, R.C.3
Thomas, T.E.4
Harley, C.B.5
Lansdorp, P.L.6
-
42
-
-
0029924534
-
From telomere loss to p53 activation and induction of a DNA-damage pathway at senescence: The telomere loss/DNA damage model of cell aging
-
VAZIRI, H. From telomere loss to p53 activation and induction of a DNA-damage pathway at senescence: The telomere loss/DNA damage model of cell aging. Exp. Geront. 31 295-302, 1996.
-
(1996)
Exp. Geront.
, vol.31
, pp. 295-302
-
-
Vaziri, H.1
-
43
-
-
0015515155
-
Origin of concatameric T4 DNA
-
WATSON, J. D. Origin of concatameric T4 DNA. Nature New Biol. 239, 197-201, 1972.
-
(1972)
Nature New Biol.
, vol.239
, pp. 197-201
-
-
Watson, J.D.1
-
44
-
-
0024366596
-
Reversible cellular senescence: Implications for immortalization of normal human diploid fibroblasts
-
WRIGHT, W.E., PEREIRA-SMITH, O.M., and SHAY, J.W. Reversible cellular senescence: Implications for immortalization of normal human diploid fibroblasts. Mol. Cell. Biol. 9, 3088-3092, 1989.
-
(1989)
Mol. Cell. Biol.
, vol.9
, pp. 3088-3092
-
-
Wright, W.E.1
Pereira-Smith, O.M.2
Shay, J.W.3
-
45
-
-
0026682717
-
Telomere positional effects and the regulation of cellular senescence
-
WRIGHT, W.E. and SHAY, J.W. Telomere positional effects and the regulation of cellular senescence. Trends Genet. 8, 193-197, 1992.
-
(1992)
Trends Genet.
, vol.8
, pp. 193-197
-
-
Wright, W.E.1
Shay, J.W.2
-
46
-
-
0025279059
-
In vivo alteration of telomere sequences and senescence caused by mutated telomerase RNAs
-
YU, G.-L., BRADLEY, J.D., ATTARDI, L.D., and BLACKBURN, E.H. In vivo alteration of telomere sequences and senescence caused by mutated telomerase RNAs. Nature 344, 126-132, 1990.
-
(1990)
Nature
, vol.344
, pp. 126-132
-
-
Yu, G.-L.1
Bradley, J.D.2
Attardi, L.D.3
Blackburn, E.H.4
-
47
-
-
0024788528
-
The structure and function of telomeres
-
ZAKIAN, V. The structure and function of telomeres. Annu. Rev. Genet. 23, 579-604, 1989.
-
(1989)
Annu. Rev. Genet.
, vol.23
, pp. 579-604
-
-
Zakian, V.1
-
48
-
-
0026668731
-
A mammalian factor that binds telomeric TTAGGG repeats in vitro
-
ZHONG, Z., SHIUE, L., KAPLAN, S., and DE LANGE, T. A mammalian factor that binds telomeric TTAGGG repeats in vitro. Mol. Cell. Biol. 12, 4834-4843, 1992.
-
(1992)
Mol. Cell. Biol.
, vol.12
, pp. 4834-4843
-
-
Zhong, Z.1
Shiue, L.2
Kaplan, S.3
De Lange, T.4
|