Pharmacokinetics of the anti-HIV bicyclam SID791 (JM3100) in rabbits, as determined by both analytical and bio-assay methods

Antiviral Chemistry and Chemotherapy

Volumn 7, Issue 1, 1996, Pages 27-30

  Witvrouw, Myriam ^a   Seifert, J M ^b   Henson, G W ^c   Martellucci, S A ^c   Desmyter, J ^a   De Clercq, E ^a  

^a REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

^b NOVARTIS PHARMA AG   (Switzerland)

^c Johnson Matthey Pharmaceutical Res   (United States)

Author keywords

Bicyclam; Bio assay; HIV; Pharmacokinetics

Indexed keywords

1,1' [1,4 PHENYLENEBIS(METHYLENE)]BIS(1,4,8,11 TETRAAZACYCLOTETRADECANE); ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; BICYCLAM DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIVIRAL ACTIVITY; AREA UNDER THE CURVE; ARTICLE; BIOASSAY; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG HALF LIFE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; INTERMETHOD COMPARISON; LYMPHOBLASTOID CELL LINE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RABBIT; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0030051924     PISSN: 09563202     EISSN: None     Source Type: Journal    
DOI: 10.1177/095632029600700105     Document Type: Article

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