Selection of binders from phage displayed antibody libraries using the BIAcore(TM) biosensor

Journal of Immunological Methods

Volumn 198, Issue 1, 1996, Pages 51-57

  Malmborg, Ann Christin ^a   Dueñas, Marta ^a   Ohlin, Mats ^a   Söderlind, Eskil ^a   Borrebaeck, Carl A K ^a  

^a LUND UNIVERSITY   (Sweden)

Author keywords

BIAcore(TM); Dissociation rate constant; Phage display; Selection

Indexed keywords

LYSOZYME; OXAZOLE DERIVATIVE;

ANTIBODY AFFINITY; ARTICLE; BIOSENSOR; DISSOCIATION CONSTANT; KINETICS; MOUSE; NONHUMAN; PHAGE DISPLAY; PRIORITY JOURNAL;

EID: 0029914097     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/0022-1759(96)00159-7     Document Type: Article

References (24)

1. BIAcore™ System Manual, 1991, version September 1991, Pharmacia Biosensor AB, Uppsala, Sweden.
2. Barbas III, C.F., Kang, A.S., Lerner, R.A. and Benkovic, S.J. (1991) Assembly of combinatorial antibody libraries on phage surfaces: the gene III site. Proc. Natl. Acad. Sci. USA 88, 7978.
3. Borrebaeck, C.A.K., Malmborg, A.-C., Furebring, C., Michaëlsson, A., Ward, S., Danielsson, L. and Ohlin, M. (1992) Kinetic analysis of recombinant antibody-antigen interactions: Relation between structural domains and antigen binding. Bio/Technology 10, 697.
4. Burton, D.R., Barbas III, C.F., Persson, M.A.A., Koenig, S., Chanock, R.M. and Lerner, R.A. (1991) A large array of human monoclonal antibodies to type 1 human immunodeficiency virus from combinatorial libraries from asymptomatic seropositive individuals. Proc. Natl. Acad. Sci. USA 88, 10134.
5. Dueñas, M. and Borrebaeck, C.A.K. (1994) Clonal selection and amplification of phage displayed antibodies by linking antigen recognition and phage replication. Bio/Technology 12, 999.
6. Dueñas, M., Chin L.-T., Malmborg, A.-C., Casalvilla, R., Ohlin, M. and Borrebaeck, C.A.K. (1996a) In vitro immunization of naive B cells yields high affinity human IgG antibodies as illustrated by phage display. Immunology, in press.
7. Dueñas, M., Malmborg, A.-C., Casalvilla, R., Ohlin, M. and Borrebaeck, C.A.K. (1996b) Selection of phage displayed antibodies based on kinetic constants. Mol. Immunol. 33, 279.
8. Hawkins, R.E., Russell, S.J. and Winter, G. (1992) Selection of phage antibodies by binding affinity: mimicking affinity maturation. J. Mol. Biol. 226, 889.
9. Hoogenboom, H.R., Griffith, A.D., Johnson, K.S., Hudson, P. and Winter, G. (1991) Multi-subunit proteins on the surface of filamentous phage: methodologies for displaying antibody (Fab) heavy and light chains. Nucleic Acids Res. 19, 4133.
10. Jönsson, U., Fägerstam, L., Ivarsson, B., Lundh, K., Löfås, S., Persson, B., Roos, H., Rönnberg, I., Sjölander, S., Stenberg, E., Ståhlberg, R., Urbaniczky C., Östlin H. and Malmqvist M. (1991) Real-time biospecific interaction analysis using surface plasmon resonance and a sensorchip technology. BioTechniques 11, 620.
11. Karlsson, R., Michaëlsson, A. and Mattsson, L. (1991) Kinetic analysis of monoclonal antibody-antigen interactions with a new biosensor based analytical system. J. Immunol. Methods 145, 229.
12. Lasonder, E., Schellekens, G.A. and Welling, G.W. (1994) A fast and sensitive method for the evaluation of the binding of phage clones selected from a surface displayed library. Nucleic Acids Res. 22,545.
13. Liedberg, B., Nylander, C. and Lundström, I. (1983) Surface plasmon resonance for gas detection and biosensoring. Sensors Actuators 4, 299.
14. Malmborg, A.-C., Michaëlsson, A., Ohlin, M., Jansson B. and Borrebaeck, C.A.K. (1992) Real time analysis of antibody-antigen reaction kinetics. Scand. J. Immunol. 35, 643.
15. Malmqvist, M. (1993) Real-time biospecific interaction analysis for the direct measurement of antibody-antigen interactions. In: J.P. Gosling and D. Reen (Eds.), Immunotechnology Proceedings of the 21st FEBS Meeting, Dublin 1993. Portland Press, London, pp. 61-75.
16. Marks, J.D., Hoogenboom, H.R., Bonnert, T.P., McCafferty, J., Griffith, A.D. and Winter, G. (1991) By-passing humanization: Human antibodies from V-gene libraries displayed on phage. J. Mol. Biol. 222, 581.
17. McCafferty, J., Griffith, A.D., Winter, G. and Chiswell, D.J. (1990) Phage antibodies: filamentous phage displaying antibody variable domains. Nature 348, 552.
18. Meyer, H., Sundqvist, V.-A., Pereira, L. and Mach, M. (1990) The gp116 of the gp58/116 complex of human cytomegalovirus represents the amino-terminal part of the precursor molecule and contains a neutralizing epitope. J. Gen. Virol. 71, 2443.
19. Ohlin, M., Owman, H., Mach, M. and. Borrebaeck C.A.K. (1996) Light Chain shuffling of a high affinity antibody results in a drift in epitope recognition. Mol. Immunol. 33, 47.
20. Pack, P., Kujau, M., Schroeckh, V., Knupfer, U., Wenderoth, R., Riesenberg, D. and Pluckthun, A. (1993) Improved bivalent miniantibodies, with identical avidity as whole antibodies, produced by high cell density fermentation of Escherichia coli. Bio/Technology 11, 1271.
21. Parmley, S.F. and Smith, G.P. (1988) Antibody-selectable filamentous fd phage vectors: affinity purification of target genes. Gene 73, 305.
22. Putney, S.D., Matthews, T.J., Robey, W.G., Lynn, D.L., Robert-Guroff, M., Mueller, W.T., Langlois, A.J., Ghrayeb, J., Petteway, S.R., Weinhold, K.J., Fischinger, P.J., Wong-Staal, F., Gallo, R.C. and Bolognesi, D.P. (1986) HTLV-III/LAV-neutralizing antibodies to an E. coli produced fragment of the virus envelope. Science 234, 1392.
23. Schier, R., Bye, J., Apell, G., McCall, A., Adams, G.P., Malmqvist, M., Weiner, L.M. and Marks, J.D. (1996) Isolation of high-affinity monomeric human anli-c-erb B-2 single chain Fv using affinity-driven selection. J. Mol. Biol. 255, 28.
24. Söderlind, E., Simonsson Lagerkvist, A.C., Dueñas, M., Malmborg, A.-C., Ayala, M., Danielsson, L. and Borrebaeck, C.A.K. (1993) Chaperonin assisted phage display of antibody fragments on filamentous bacteriophages. Bio/Technology 11, 503.