A glutathione S-transferases isozyme (bGST 5.8) involved in the metabolism of 4-hydroxy-2-trans-nonenal is localized in bovine lens epithelium

Experimental Eye Research

Volumn 63, Issue 3, 1996, Pages 329-337

  Srivastava, Sanjay K ^a   Singhal, Sharad S ^b   Awasthi, Sanjay ^b   Pikula, Slawomir ^a,c   Ansari, Naseem H ^a   Awasthi, Yogesh C ^a  

^a UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

^b University of Texas Medical Branch School of Medicine   (United States)

^c NENCKI INSTITUTE OF EXPERIMENTAL BIOLOGY   (Poland)

Author keywords

4 hydroxy 2 trans nonenal; bovine lens epithelium; glutathione; glutathione S transferases; lipid hydroperoxides; lipid peroxidation

Indexed keywords

4 HYDROXYNONENAL; GLUTATHIONE TRANSFERASE;

ANIMAL TISSUE; ARTICLE; CATTLE; ELECTROPHORESIS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; LENS EPITHELIUM; LIPID PEROXIDATION; NONHUMAN; PRIORITY JOURNAL;

EID: 0030249229     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1006/exer.1996.0122     Document Type: Article

References (49)

1. Ahmad, H., Sharma, R., Mansour, A. and Awasthi, Y. C. (1992). t-Butylated hydroxytoluene enhances intracellular levels of glutathione and related enzymes of rat lens in vitro organ culture. Exp. Eye Res. 54, 41-8.
2. Alin, P., Danielson, U. H. and Mannervik, B. (1985). 4-Hydroxy-2-enals are substrates for glutathione transferase. FEBS Lett. 179, 267-70.
3. Augusteyn, R. C. (1981). Protein modification in cataract: possible oxidative mechanisms. In Mechanisms of Cataract Formation in the Human Lens. (Ed. Duncan, G.). Pp. 72-115, Academic Press, New York, U.S.A.
4. Awasthi, Y. C., Dao, D. D. and Saneto, R. P. (1980). Interrelationship between anionic and cationic forms of glutathione S-transferases of human liver. Biochem. J. 191, 1-10.
5. Awasthi, Y. C., Zimniak, P., Singhal, S. S. and Awasthi, S. (1995). Physiological role of glutathione S-transferases in protection mechanisms against lipid peroxidation. A commentary. Biochem. Arch. 11, 47-54.
6. Babizhayev, M. A. and Deyev, A. I. (1986). Free radical oxidation of lipid and thiol groups in genesis of cataract. Biophysics 31, 119-25.
7. Babizhayev, M. A., Deyev, A. I. and Linberg, L. F. (1988). Lipid peroxidation as a possible cause of cataract. Mech. Ageing Develop. 44, 69-89.
8. Bhatnagar, A., Ansari, H. N., Zacarias, A. and Srivastava, S. K. (1993). Digital image analysis of cultured rat lens during oxidative stress-induced cataractogenesis. Exp. Eye Res. 56, 385-91.
9. Bhuyan, K. C. and Bhuyan, D. K. (1983). Molecular mechanism of cataractogenesis: II. Evidence of lipid peroxidation and membrane damage. In Oxy Radicals and their Scavenger Systems (Eds. Greenwald, R. A. and Cohen, G.), Pp. 349-56, Elsevier Science Publishing: New York, U.S.A.
10. Bhuyan, K. C. and Bhuyan, D. K. (1984). Molecular mechanism of cataractogenesis: III. Toxic metabolites of oxygen as initiators of lipid peroxidation and cataract. Curr. Eye Res. 3, 67-81.
11. Bhuyan, K. C., Bhuyan, D. K. and Podos, S. M. (1979). Lipid peroxidation and membrane damage in the pathogenesis of cataract. Invest. Ophthalmol. Vis. Sci. 18 (Suppl.), 97 (Abs. 4).
12. Bhuyan, K. C., Bhuyan, D. K. and Podos, S. M. (1981). Evidence of increased lipid peroxidation in cataracts. I.R.C.S. Med. Sci. 9, 126-7.
13. Bjornestedt, R., Tardioli, S. and Mannervik, B. (1995). The high activity of rat glutathione transferase 8-8 with alkene substrates is dependent on a glycine residue in the active site. J. Biol. Chem. 270, 29705-9.
14. Bloemendal, H. (1992). Disorganization of members and abnormal intermediate filament assembly lead to cataract. Proctor Award Lecture. Invest. Ophthalmol. Vis. Sci. 32, 445-55.
15. Bradford, M. M. (1976). A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-54.
16. Dische, Z. and Zil, H. (1951). Studies on the oxidation of cysteine to cystine in lens proteins during cataract formation. Am. J. Ophthalmol. 34, 104-13.
17. Esterbauer, H., Schaur, R. J. and Zollner, H. (1991). Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radical Biol. Med. 11, 81-128.
18. Giblin, F. J., McCready, J. P., Schrimscher, L. and Reddy, V. N. (1987). Peroxide-induced effects on lens cation transport following inhibition of glutathione reductase activity in vitro. Exp. Eye Res. 45, 77-9.
19. Hayes, J. D. (1986). Purification and physical characterization of glutathione S-transferase K : differential use of S-hexylglutathione and glutathione affinity matrices to isolate a novel glutathione S-transferase from rat liver. Biochem. J. 233, 789-98.
20. Hayes, J. D. and Pulford, D.J. (1995). The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemo-protection and drug resistance. Crit. Rev. Biochem. Mol. Biol. 30, 445-600.
21. Jensson, H., Guthenberg, C., Alin, P. and Mannervik, B. (1986). Rat glutathione transferase 8-8, an enzyme efficiently detoxifying 4-hydroxyalk-2-enals. FEBS Lett. 203, 207-9.
22. Khan, M. F., Srivastava, S. K., Singhal, S. S., Chaubey, M., Awasthi, S., Petersen, D. R., Ansari, G. A. S. and Awasthi, Y. C. (1995). Iron induced lipid peroxidation in rat liver is accompanied with preferential induction of glutathione S-transferase 8-8 isozyme. Toxicol. Appl. Pharmacol. 131, 63-72.
23. Kurita, Y., Tsuboi, R., Ueki, R., Rifkin, D. B. and Ogawa, H. (1992). Immunohistochemical localization of basic fibroblast growth factor in wound healing sites of mouse skin. Arch. Dermatol. Res. 284, 193-7.
24. Laemmli, U. K. (1970). Cleavage of structural proteins during the assembly of the head of bacteriophase T4. Nature 227, 680-5.
25. Little, C. and O'Brien, P. J. (1968). An Intracellular GSH-peroxidase with a lipid peroxide substrate. Biochem. Biophys. Res. Commun. 31, 145-50.
26. Medh, R. D., Saxena, M., Singhal, S. S., Ahmad, H. and Awasthi, Y. C. (1991). Characterization of a novel glutathione S-transferase isoenzyme from mouse lung and liver having structural homology with rat GST 8-8. Biochem. J. 278, 793-9.
27. Meyer, D. J., Lalor, E., Coles, B., Kispert, A., Alin, P., Mannervik, B. and Ketterer, B. (1989). Single-step purification and h.p.l.c. analysis of glutathione transferase 8-8 in rat tissues. Biochem. J. 260, 785-8.
28. Prohaska, J. R. and Ganther, H. E. (1977). The glutathione peroxidase activity of glutathione S-transferase. Biochem. Biophys. Res. Commun. 76, 437-45.
29. Schocket, S. S., Esterson, J., Bradford, B., Michaelis, M. and Richards, R. D. (1972). Induction of cataracts in mice by exposure to oxygen. Isr. J. Med. Sci. 8, 1596-601.
30. Sharma, R., Gupta, S., Singhal, S. S., Ansari, G. A. S. and Awasthi, Y. C. (1991). Glutathione S-transferase-catalyzed conjugation of 9,10-epoxystearic acid with glutathione. J. Biochem. Toxicol. 6, 147-53.
31. Singhal, S. S., Saxena, M., Ahmad, H., Awasthi, S., Haque, A. and Awasthi, Y. C. (1992). Glutathione S-transferases of human lung: characterization and evaluation of the protective role of the α-class isozyme against lipid peroxidation. Arch. Biochem. Biophys. 299, 232-41.
32. Singhal, S. S., Zimniak, P., Awasthi, S., Piper, J. T., He, N. G., Teng, J. I., Petersen, D. R. and Awasthi, Y. C. (1994). Several closely related glutathione S-transferase isozymes catalyzing conjugation of 4-hydroxynonenal are differentially expressed in human tissues. Arch. Biochem. Biophys. 311, 242-50.
33. Singhal, S. S., Awasthi, S., Srivastava, S. K., Zimniak, P., Ansari, N. H. and Awasthi, Y. C. (1995). Novel human ocular glutathione S-transferases with high activity towards 4-hydroxynonenal. Invest. Ophthalmol. Vis. Sci. 36, 142-50.
34. Spector, A. (1991). The lens and oxidative stress. In Oxidative Stress, Oxidants and Antioxidants. (Ed. Sies, H.), Pp. 529-558. Academic Press: London.
35. Spector, A., Wang, G. M. and Wang, R. R. (1993). Photochemically induced cataracts in rat lenses can be prevented by AL-3823A, a glutathione peroxidase mimic. Proc. Natl. Acad. Sci., USA 90, 7485-9.
36. 2 and photochemically induced cataract. Curr. Eye Res. 12, 163-79.
37. Srivastava, S. K. and Ansari, N. H. (1988). Prevention of sugar-induced cataractogenesis in rat by butylated hydroxytoluene. Diabetes 37, 1505-8.
38. Srivastava, S. K., Singhal, S. S., Bajpai, K. K., Chaubey, M., Ansari, N. H. and Awasthi, Y. C. (1994). A group of novel glutathione S-transferase isozymes showing high activity towards 4-hydroxy-2-nonenal are present in bovine ocular tissues. Exp. Eye Res. 59, 151-9.
39. Srivastava, S. K., Awasthi, S., Bhatnagar, A. and Awasthi, Y. C. (1996). Lenses of curcumin fed rats are resistant to the cataractogenic effect of 4-hydroxynonenal in organ cultures. ARVO Annual meeting, Fort Lauderdale, Florida. Invest. Ophthalmol. Vis. Sci. 37 (Suppl.), Abs. 4080.
40. Stenberg, G., Ridderstrom, M., Engstrom, A., Pemble, S. E. and Mannervik, B. (1992). Cloning and heterologous expression of cDNA encoding class alpha rat glutathione transferase 8-8, an enzyme with high catalytic activity towards genotoxic α,β-unsaturated carbonyl compounds. Biochem. J. 284, 313-19.
41. Towbin, H., Staehelin, T. and Gordon, J. (1979). Electrophoretic transfer of proteins from acrylamide gels to nitrocellulose sheet: procedure and some applications. Proc. Natl. Acad. Sci., USA 76, 4350-4.
42. Ursini F., Maiorino, M. and Gregolin, C. (1985). The selenoenzyme phospholipid hydroperoxide glutathione peroxidase. Biochim. Biophys. Acta 839, 62-70.
43. Ursini F., Maiorino, M., Valente, M., Ferri, L. and Gregolin, C. (1982). Purification from pig liver of a protein which protects liposomes and biomembranes from peroxidative degradation and exhibits glutathione peroxidase activity on phosphatidylcholine hydroperoxides. Biochim. Biophys. Acta 710, 197-211.
44. Varma, S. D. (1991). Scientific basis for medical therapy of cataracts by antioxidants. Am. J. Clin. Nutr. 53, 335S-45S.
45. Varma, S. D., Devamanoharan, P. S. and Morris, S. M. (1995). Prevention of cataracts by nutritional and metabolic antioxidants. Crit. Rev. Food Sci. Nutr. 35, 111-29.
46. Wendel, A. (1980). Glutathione peroxidase. In Enzymatic Basis of Detoxification (Ed. Jakoby, W. B.). Pp. 333-353, Academic Press: New York, U.S.A.
47. 2 and chelated iron. Free Radical Biol. Med. 7, 499-505.
48. Zimniak, P., Eckles, M. A., Saxena, M. and Awasthi, Y. C. (1992). A subgroup of class a glutathione S-transferases: cloning of a cDNA for mouse lung glutathione S-transferase GST 5.7. FEBS Lett. 313, 173-6.
49. Zimniak, P., Singhal, S. S., Srivastava, S K., Awasthi, S., Sharma, R., Hayden, J. B. and Awasthi, Y. C. (1994). Estimation of genomic complexity, heterologous expression and enzymatic characterization of mouse glutathione S-transferase mGSTA4-4 (GST 5.7). J. Biol. Chem. 269, 992-1000.