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Volumn 16, Issue 5, 1996, Pages 999-1009

Mutations in a C. elegans Gqα gene disrupt movement, egg laying, and viability

Author keywords

[No Author keywords available]

Indexed keywords

ARECOLINE; GUANINE NUCLEOTIDE BINDING PROTEIN; PHOSPHOLIPASE C;

EID: 0029898923     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0896-6273(00)80123-3     Document Type: Article
Times cited : (161)

References (52)
  • 1
    • 0028330364 scopus 로고
    • Cloning and characterization of the choline acetyltransferase structural gene (cha-1) from C. Elegans
    • Alfonso, A., Grundahl, K., McManus, J.R., and Rand, J.B. (1994). Cloning and characterization of the choline acetyltransferase structural gene (cha-1) from C. elegans. J. Neurosci. 14, 2290-2300.
    • (1994) J. Neurosci. , vol.14 , pp. 2290-2300
    • Alfonso, A.1    Grundahl, K.2    McManus, J.R.3    Rand, J.B.4
  • 2
    • 0027391513 scopus 로고
    • Splicing in Caenorhabditis elegans does not require an AG at the 3′ splice acceptor site
    • Aroian, R.V., Levy, A.D., Koga, M., Ohshima, Y., Kramer, J. M., Sternberg, P. W. (1993) Splicing in Caenorhabditis elegans does not require an AG at the 3′ splice acceptor site. Mol. Cell. Biol. 13, 626-637.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 626-637
    • Aroian, R.V.1    Levy, A.D.2    Koga, M.3    Ohshima, Y.4    Kramer, J.M.5    Sternberg, P.W.6
  • 3
    • 0027528788 scopus 로고
    • The genetics of feeding in Caenorhabditis elegans
    • Avery, L. (1993a). The genetics of feeding in Caenorhabditis elegans. Genetics 133, 897-917.
    • (1993) Genetics , vol.133 , pp. 897-917
    • Avery, L.1
  • 4
    • 0027548890 scopus 로고
    • Motor-neuron M3 controls pharyngeal muscle relaxation timing in Caenorhabditis elegans
    • Avery, L. (1993b). Motor-neuron M3 controls pharyngeal muscle relaxation timing in Caenorhabditis elegans. J. Exp. Biol. 175, 283-297.
    • (1993) J. Exp. Biol. , vol.175 , pp. 283-297
    • Avery, L.1
  • 5
    • 0023663870 scopus 로고
    • A cell that dies during wild-type C. Elegans development can function as a neuron in a ced-3 mutant
    • Avery, L., and Horvitz, H.R. (1987). A cell that dies during wild-type C. elegans development can function as a neuron in a ced-3 mutant. Cell 51, 1071-1078.
    • (1987) Cell , vol.51 , pp. 1071-1078
    • Avery, L.1    Horvitz, H.R.2
  • 6
    • 0025063432 scopus 로고
    • Effects of starvation and neuroactive drugs on feeding in Caenorhabditis elegans
    • Avery, L., and Horvitz, H. R. (1990). Effects of starvation and neuroactive drugs on feeding in Caenorhabditis elegans. J. Exp. Zool. 253, 263-270.
    • (1990) J. Exp. Zool. , vol.253 , pp. 263-270
    • Avery, L.1    Horvitz, H.R.2
  • 7
    • 0028227013 scopus 로고
    • Structure and function of receptors coupled to G proteins
    • Baldwin, J.M. (1994). Structure and function of receptors coupled to G proteins. Curr. Opin. Cell Biol. 6, 180-190.
    • (1994) Curr. Opin. Cell Biol. , vol.6 , pp. 180-190
    • Baldwin, J.M.1
  • 8
    • 0024319166 scopus 로고
    • The basal component of the nematode dense-body is vinculin
    • Barstead, R.J., and Waterston, R.H. (1989). The basal component of the nematode dense-body is vinculin. J. Biol. Chem. 264, 10177-10185.
    • (1989) J. Biol. Chem. , vol.264 , pp. 10177-10185
    • Barstead, R.J.1    Waterston, R.H.2
  • 9
    • 0028609612 scopus 로고
    • Interaction of endothelin-3 with endothelin-B receptor is essential for development of epidermal melanocytes and enteric neurons
    • Baynash, A.G., Hosoda, K., Giaid, A., Richardson, J.A., Emoto, N., Hammer, R.E., and Yanagisawa, M. (1994). Interaction of endothelin-3 with endothelin-B receptor is essential for development of epidermal melanocytes and enteric neurons. Cell 79, 1277-1285.
    • (1994) Cell , vol.79 , pp. 1277-1285
    • Baynash, A.G.1    Hosoda, K.2    Giaid, A.3    Richardson, J.A.4    Emoto, N.5    Hammer, R.E.6    Yanagisawa, M.7
  • 10
    • 0016063911 scopus 로고
    • The genetics of Caenorhabditis elegans
    • Brenner, S. (1974). The genetics of Caenorhabditis elegans. Genetics 77, 71-94.
    • (1974) Genetics , vol.77 , pp. 71-94
    • Brenner, S.1
  • 11
    • 0026676806 scopus 로고
    • Isozyme-selective stimulation of phospholipase Cβ2 by G protein βγ subunits
    • Camps, M., Carozzi, A., Schnabel, P., Scheer, A., Parker, P. J., and Gierschik, P. (1992). Isozyme-selective stimulation of phospholipase Cβ2 by G protein βγ subunits. Nature 360, 684-686.
    • (1992) Nature , vol.360 , pp. 684-686
    • Camps, M.1    Carozzi, A.2    Schnabel, P.3    Scheer, A.4    Parker, P.J.5    Gierschik, P.6
  • 12
    • 0000365871 scopus 로고
    • Toward a physical map of the genome of the nematode Caenorhabditis elegans
    • Coulson, A., Sulston, J., Brenner, S., and Karn, J. (1986). Toward a physical map of the genome of the nematode Caenorhabditis elegans. Proc. Natl. Acad. Sci. USA 83, 7821-7825.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 7821-7825
    • Coulson, A.1    Sulston, J.2    Brenner, S.3    Karn, J.4
  • 13
    • 0020633175 scopus 로고
    • Occurrence of muscarinic acetylcholine receptors in wild-type and cholinergic mutants of C. Elegans
    • Culotti, J.G., and Klein, W.L. (1983). Occurrence of muscarinic acetylcholine receptors in wild-type and cholinergic mutants of C. elegans. J. Neurosci. 3, 359-368
    • (1983) J. Neurosci. , vol.3 , pp. 359-368
    • Culotti, J.G.1    Klein, W.L.2
  • 15
    • 0028062726 scopus 로고
    • Palmitoylation but not the extreme amino-terminus of Gqα is required for coupling to the NK2 receptor
    • Edgerton, M.D., Chabert, C., Chollet, A., and Arkinstall, S. (1994). Palmitoylation but not the extreme amino-terminus of Gqα is required for coupling to the NK2 receptor. FEBS Lett. 354, 195-199.
    • (1994) FEBS Lett. , vol.354 , pp. 195-199
    • Edgerton, M.D.1    Chabert, C.2    Chollet, A.3    Arkinstall, S.4
  • 17
    • 0025047347 scopus 로고
    • Characterization of a G-protein α-subunit gene from the nematode Caenorhabditis elegans
    • Fino Silva, I., and Plasterk, R.H.A. (1990). Characterization of a G-protein α-subunit gene from the nematode Caenorhabditis elegans. J. Mol. Biol. 215, 483-487.
    • (1990) J. Mol. Biol. , vol.215 , pp. 483-487
    • Fino Silva, I.1    Plasterk, R.H.A.2
  • 19
    • 0025844789 scopus 로고
    • Kinesin-related gene unc104 is required for axonal transport of synaptic vesicles in C. Elegans
    • Hall, D.H., and Hedgecock, E.M. (1991). Kinesin-related gene unc104 is required for axonal transport of synaptic vesicles in C. elegans. Cell 65, 837-847.
    • (1991) Cell , vol.65 , pp. 837-847
    • Hall, D.H.1    Hedgecock, E.M.2
  • 20
    • 0026676807 scopus 로고
    • Subunits βγ of heterotrimeric G protein activate β2 isoform of phospholipase C
    • Katz, A., Wu, D.Q., and Simon, M.I. (1992). Subunits βγ of heterotrimeric G protein activate β2 isoform of phospholipase C. Nature 360, 686-689.
    • (1992) Nature , vol.360 , pp. 686-689
    • Katz, A.1    Wu, D.Q.2    Simon, M.I.3
  • 21
    • 0030032001 scopus 로고    scopus 로고
    • EGL-10 regulates G proteins signaling in the C. Elegans nervous system and shares a conserved domain with many mammalian proteins
    • Koelle, M.R., and Horvitz, H.R. (1996). EGL-10 regulates G proteins signaling in the C. elegans nervous system and shares a conserved domain with many mammalian proteins. Cell 84, 115-125.
    • (1996) Cell , vol.84 , pp. 115-125
    • Koelle, M.R.1    Horvitz, H.R.2
  • 22
    • 0029664589 scopus 로고    scopus 로고
    • The 2.0 angstrom crystal structure of a heterotrimeric G protein
    • Lambright, D.G., Sondek, J., Bohm, A., Skiba, N.P., Hamm, H.E., and Sigler, P. B. (1996). The 2.0 angstrom crystal structure of a heterotrimeric G protein. Nature 379, 311-319.
    • (1996) Nature , vol.379 , pp. 311-319
    • Lambright, D.G.1    Sondek, J.2    Bohm, A.3    Skiba, N.P.4    Hamm, H.E.5    Sigler, P.B.6
  • 23
    • 0027120839 scopus 로고
    • Members of the Gqα subunit gene family activate phospholipase Cβ isozymes
    • Lee, C.H., Park, D., Wu, D., Rhee, S.G., and Simon, M.I. (1992). Members of the Gqα subunit gene family activate phospholipase Cβ isozymes. J. Biol. Chem. 267, 16044-16047.
    • (1992) J. Biol. Chem. , vol.267 , pp. 16044-16047
    • Lee, C.H.1    Park, D.2    Wu, D.3    Rhee, S.G.4    Simon, M.I.5
  • 24
    • 0025633502 scopus 로고
    • dgq: a drosophila gene encoding a visual system-specific G α molecule
    • Lee, Y.J., Dobbs, M.B., Verardi, M.L., and Hyde, D.R. (1990). dgq: a drosophila gene encoding a visual system-specific G α molecule. Neuron 5, 889-898.
    • (1990) Neuron , vol.5 , pp. 889-898
    • Lee, Y.J.1    Dobbs, M.B.2    Verardi, M.L.3    Hyde, D.R.4
  • 25
    • 0026112303 scopus 로고
    • Homologous and unique G protein α subunits in the nematode Caenorhabditis elegans
    • Lochrie, M.A., Mendel, J.E., Sternberg, P.W., and Simon, M.I. (1991). Homologous and unique G protein α subunits in the nematode Caenorhabditis elegans. Cell Regul. 2, 135-154.
    • (1991) Cell Regul. , vol.2 , pp. 135-154
    • Lochrie, M.A.1    Mendel, J.E.2    Sternberg, P.W.3    Simon, M.I.4
  • 26
    • 0027272707 scopus 로고
    • Genes required for GABA function in Caenorhabditis elegans
    • McIntire, S.L., Jorgensen, E., and Horvitz, H.R. (1993). Genes required for GABA function in Caenorhabditis elegans. Nature 364, 334-337.
    • (1993) Nature , vol.364 , pp. 334-337
    • McIntire, S.L.1    Jorgensen, E.2    Horvitz, H.R.3
  • 27
    • 0027154645 scopus 로고
    • Two types of sites required for meiotic chromosome-pairing in Caenorhabditis elegans
    • McKim, K.S, Peters, K., and Rose, A.M. (1993). Two types of sites required for meiotic chromosome-pairing in Caenorhabditis elegans. Genetics 134, 749-768.
    • (1993) Genetics , vol.134 , pp. 749-768
    • McKim, K.S.1    Peters, K.2    Rose, A.M.3
  • 30
    • 0027132717 scopus 로고
    • The 2.2 a crystal structure of transducin-α complexed with GTP-γS
    • Noel, J.P., Hamm, H., and Sigler, P.B. (1993). The 2.2 A crystal structure of transducin-α complexed with GTP-γS. Nature 366, 654-663.
    • (1993) Nature , vol.366 , pp. 654-663
    • Noel, J.P.1    Hamm, H.2    Sigler, P.B.3
  • 34
    • 0022476162 scopus 로고
    • Mutations with dominant effects on the behavior and morphology of the nematode Caenorhabditis elegans
    • Park, E.C., and Horvitz, H.R. (1986). Mutations with dominant effects on the behavior and morphology of the nematode Caenorhabditis elegans. Genetics 113, 821-852.
    • (1986) Genetics , vol.113 , pp. 821-852
    • Park, E.C.1    Horvitz, H.R.2
  • 35
    • 0028871952 scopus 로고
    • Interacting genes required for pharyngeal excitation by motor neuron MC in Caenorhabditis elegans
    • Raizen, D.M., Lee, R.Y.N., and Avery, L. (1995). Interacting genes required for pharyngeal excitation by motor neuron MC in Caenorhabditis elegans. Genetics 141, 1365-1382.
    • (1995) Genetics , vol.141 , pp. 1365-1382
    • Raizen, D.M.1    Lee, R.Y.N.2    Avery, L.3
  • 36
    • 0028810710 scopus 로고
    • Analysis of dominant mutations affecting muscle excitation in C. Elegans
    • Reiner, D.J., Weinshenker, D., and Thomas, J.H. (1995). Analysis of dominant mutations affecting muscle excitation in C. elegans. Genetics 141, 961-976.
    • (1995) Genetics , vol.141 , pp. 961-976
    • Reiner, D.J.1    Weinshenker, D.2    Thomas, J.H.3
  • 38
    • 0025834532 scopus 로고
    • Diversity of G proteins in signal transduction
    • Simon, M.I., Strathmann, M.P., and Gautam, N. (1991). Diversity of G proteins in signal transduction. Science 252, 802-808.
    • (1991) Science , vol.252 , pp. 802-808
    • Simon, M.I.1    Strathmann, M.P.2    Gautam, N.3
  • 40
    • 0025695580 scopus 로고
    • G protein diversity: A distinct class of α subunits is present in vertebrates and invertebrates
    • Strathmann, M., and Simon, M.I. (1990). G protein diversity: a distinct class of α subunits is present in vertebrates and invertebrates. Proc. Natl. Acad. Sci. USA 87, 9113-9117.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 9113-9117
    • Strathmann, M.1    Simon, M.I.2
  • 41
    • 0000182225 scopus 로고
    • Methods
    • W.B. Wood, ed. (Cold Spring Harbor, New York: Cold Spring Harbor Press)
    • Sulston, J., and Hodgkin, J. (1988). Methods. In The Nematode Caenorhabditis elegans, W.B. Wood, ed. (Cold Spring Harbor, New York: Cold Spring Harbor Press), pp. 587-606.
    • (1988) The Nematode Caenorhabditis Elegans , pp. 587-606
    • Sulston, J.1    Hodgkin, J.2
  • 42
    • 0019311310 scopus 로고
    • Regulation and cell autonomy during postembryonic development of C. Elegans
    • Sulston, J.E., and White, J.G. (1980). Regulation and cell autonomy during postembryonic development of C. elegans. Dev. Biol. 78, 577-597.
    • (1980) Dev. Biol. , vol.78 , pp. 577-597
    • Sulston, J.E.1    White, J.G.2
  • 43
    • 0020808726 scopus 로고
    • Egg-laying defective mutants of the nematode Caenorhabditis elegans
    • Trent, C., Tsung, N., and Horvitz, R. (1983). Egg-laying defective mutants of the nematode Caenorhabditis elegans. Genetics 104, 619-647.
    • (1983) Genetics , vol.104 , pp. 619-647
    • Trent, C.1    Tsung, N.2    Horvitz, R.3
  • 44
    • 0025302932 scopus 로고
    • Characterization of a G-protein β-subunit gene from the nematode Caenorhabditis elegans
    • van der Voorn, L., Gebbink, M., Plasterk, R.H.A., and Ploegh, H.L. (1990). Characterization of a G-protein β-subunit gene from the nematode Caenorhabditis elegans. J. Mol. Biol. 213, 17-26.
    • (1990) J. Mol. Biol. , vol.213 , pp. 17-26
    • Van Der Voorn, L.1    Gebbink, M.2    Plasterk, R.H.A.3    Ploegh, H.L.4
  • 45
    • 0018961312 scopus 로고
    • Mutants with altered muscle structure in C. Elegans
    • Waterston, R.H., Thomson, J.N., and Brenner, S. (1980). Mutants with altered muscle structure in C. elegans. Dev. Biol. 77, 271-302.
    • (1980) Dev. Biol. , vol.77 , pp. 271-302
    • Waterston, R.H.1    Thomson, J.N.2    Brenner, S.3
  • 48
    • 0028835184 scopus 로고
    • Genetic and pharmacological analysis of neurotransmitters controlling egg laying in C. Elegans
    • Weinshenker, D., Garriga, G., and Thomas, J.H. (1995). Genetic and pharmacological analysis of neurotransmitters controlling egg laying in C. elegans. J. Neurosci. 15, 6975-6985.
    • (1995) J. Neurosci. , vol.15 , pp. 6975-6985
    • Weinshenker, D.1    Garriga, G.2    Thomas, J.H.3
  • 50
    • 0028089203 scopus 로고
    • Genes critical for muscle development and function in Caenorhabditis elegans identified through lethal mutations
    • Williams, B.D., and Waterston, R.H. (1994). Genes critical for muscle development and function in Caenorhabditis elegans identified through lethal mutations. J. Cell Biol. 124, 475-490.
    • (1994) J. Cell Biol. , vol.124 , pp. 475-490
    • Williams, B.D.1    Waterston, R.H.2
  • 52
    • 0027279671 scopus 로고
    • G protein-coupled signal transduction pathways for interleukin-8
    • Wu, D., LaRosa, G.J., and Simon, M.I. (1993). G protein-coupled signal transduction pathways for interleukin-8. Science 261, 101-103.
    • (1993) Science , vol.261 , pp. 101-103
    • Wu, D.1    LaRosa, G.J.2    Simon, M.I.3


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