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Volumn 15, Issue 7-8, 1996, Pages 1383-1395

An extended phosphate linkage: Synthesis, hybridization and modeling studies of modified oligonucleotides

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; COMPLEMENTARY DNA; OLIGONUCLEOTIDE; PHOSPHORAMIDIC ACID DERIVATIVE; RIBONUCLEASE; THYMIDINE DERIVATIVE;

EID: 0029894166     PISSN: 07328311     EISSN: None     Source Type: Journal    
DOI: 10.1080/07328319608002438     Document Type: Article
Times cited : (9)

References (46)
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    • 0004261876 scopus 로고
    • R. G. Landes Company: Austin, Texas
    • Selected books and reviews published in 1995 (a) Therapeutic Applications of Oligonucleotides Crooke, S.T., Ed.; R. G. Landes Company: Austin, Texas, 1995; (b) Carbohydrate Modifications in Antisense Research Sanghvi, Y.S.; Cook, P.D., Eds.; ACS Publications, Symposium Series 580: Washington, DC, 1995; (c) Crooke, S.T. Hematologie Path. 1995, 9, 59 (d) Crooke, S.T. in Burger's Medicinal Chemistry and Drug Discovery, Vol 1; Wolff, M.E., Ed.; John Wiley: New York, 1995; p. 863 (e) Mesmaeker, A.D.; Häner, R.; Martin, P.; Moser, H.E. Acc. Chem. Res. 1995, 28, 366.
    • (1995) Therapeutic Applications of Oligonucleotides
    • Crooke, S.T.1
  • 2
    • 8944230922 scopus 로고
    • ACS Publications, Symposium Series 580: Washington, DC
    • Selected books and reviews published in 1995 (a) Therapeutic Applications of Oligonucleotides Crooke, S.T., Ed.; R. G. Landes Company: Austin, Texas, 1995; (b) Carbohydrate Modifications in Antisense Research Sanghvi, Y.S.; Cook, P.D., Eds.; ACS Publications, Symposium Series 580: Washington, DC, 1995; (c) Crooke, S.T. Hematologie Path. 1995, 9, 59 (d) Crooke, S.T. in Burger's Medicinal Chemistry and Drug Discovery, Vol 1; Wolff, M.E., Ed.; John Wiley: New York, 1995; p. 863 (e) Mesmaeker, A.D.; Häner, R.; Martin, P.; Moser, H.E. Acc. Chem. Res. 1995, 28, 366.
    • (1995) Carbohydrate Modifications in Antisense Research
    • Sanghvi, Y.S.1    Cook, P.D.2
  • 3
    • 0028916028 scopus 로고
    • Selected books and reviews published in 1995 (a) Therapeutic Applications of Oligonucleotides Crooke, S.T., Ed.; R. G. Landes Company: Austin, Texas, 1995; (b) Carbohydrate Modifications in Antisense Research Sanghvi, Y.S.; Cook, P.D., Eds.; ACS Publications, Symposium Series 580: Washington, DC, 1995; (c) Crooke, S.T. Hematologie Path. 1995, 9, 59 (d) Crooke, S.T. in Burger's Medicinal Chemistry and Drug Discovery, Vol 1; Wolff, M.E., Ed.; John Wiley: New York, 1995; p. 863 (e) Mesmaeker, A.D.; Häner, R.; Martin, P.; Moser, H.E. Acc. Chem. Res. 1995, 28, 366.
    • (1995) Hematologie Path. , vol.9 , pp. 59
    • Crooke, S.T.1
  • 4
    • 0001675653 scopus 로고
    • Wolff, M.E., Ed.; John Wiley: New York
    • Selected books and reviews published in 1995 (a) Therapeutic Applications of Oligonucleotides Crooke, S.T., Ed.; R. G. Landes Company: Austin, Texas, 1995; (b) Carbohydrate Modifications in Antisense Research Sanghvi, Y.S.; Cook, P.D., Eds.; ACS Publications, Symposium Series 580: Washington, DC, 1995; (c) Crooke, S.T. Hematologie Path. 1995, 9, 59 (d) Crooke, S.T. in Burger's Medicinal Chemistry and Drug Discovery, Vol 1; Wolff, M.E., Ed.; John Wiley: New York, 1995; p. 863 (e) Mesmaeker, A.D.; Häner, R.; Martin, P.; Moser, H.E. Acc. Chem. Res. 1995, 28, 366.
    • (1995) Burger's Medicinal Chemistry and Drug Discovery , vol.1 , pp. 863
    • Crooke, S.T.1
  • 5
    • 0345706517 scopus 로고
    • Selected books and reviews published in 1995 (a) Therapeutic Applications of Oligonucleotides Crooke, S.T., Ed.; R. G. Landes Company: Austin, Texas, 1995; (b) Carbohydrate Modifications in Antisense Research Sanghvi, Y.S.; Cook, P.D., Eds.; ACS Publications, Symposium Series 580: Washington, DC, 1995; (c) Crooke, S.T. Hematologie Path. 1995, 9, 59 (d) Crooke, S.T. in Burger's Medicinal Chemistry and Drug Discovery, Vol 1; Wolff, M.E., Ed.; John Wiley: New York, 1995; p. 863 (e) Mesmaeker, A.D.; Häner, R.; Martin, P.; Moser, H.E. Acc. Chem. Res. 1995, 28, 366.
    • (1995) Acc. Chem. Res. , vol.28 , pp. 366
    • Mesmaeker, A.D.1    Häner, R.2    Martin, P.3    Moser, H.E.4
  • 30
    • 8944229437 scopus 로고    scopus 로고
    • note
    • Conventionally modified backbones are incorporated utilizing a dimer strategy which may require synthesis of 16-dimers, whereas, construction of a stretched backbone can be accomplished by the use of four nucleosidic monomers (e.g. a thymidine analog 21).
  • 33
    • 8944230921 scopus 로고
    • Noordwijkerhout, The Netherlands, 6-11 August, Abstract # 016
    • (a) Synthesis of oligonucleotides containing stretched backbones 12 and 13 for triplex studies was reported at a recent meeting. However, an antisense related DNA:RNA duplex study was not reported. Pedersen, E.B.; Larson, E.; Kofoed, T.; Abdel-Aleem, A-A. Nucleic Acids Symposium, Noordwijkerhout, The Netherlands, 6-11 August, 1995, Abstract # 016.
    • (1995) Nucleic Acids Symposium
    • Pedersen, E.B.1    Larson, E.2    Kofoed, T.3    Abdel-Aleem, A.-A.4
  • 34
    • 0011950120 scopus 로고
    • Washington, DC, August 21-25, CARB 45
    • (b) Part of this work was first presented by us at an ACS meeting. Haly, B.; Bellon, L.; Sanghvi, Y.S. 208th ACS National meeting, Washington, DC, August 21-25, 1994, CARB 45.
    • (1994) 208th ACS National Meeting
    • Haly, B.1    Bellon, L.2    Sanghvi, Y.S.3
  • 40
    • 0026606239 scopus 로고
    • 4OH solution (∼30%, 1.5 ml) and heated at 55 °C (metal block) for 12 h. For more details see: Beaucage, S.L.; Iyer, R.P. Tetrahedron 1992, 48, 2223.
    • (1992) Tetrahedron , vol.48 , pp. 2223
    • Beaucage, S.L.1    Iyer, R.P.2
  • 43
    • 8944226342 scopus 로고    scopus 로고
    • note
    • CFF93 force field as implemented in Insight II/Discover software from BIOSYM Technologies, San Diego, CA 92121.
  • 45
    • 0029194414 scopus 로고
    • For experimental details see: (a) Greig, M.; Griffey, R.H. Rapid Commun. Mass Spectrom. 1995, 9, 97. (b) Srivasta, G.S.; Batt, M.; Schuette, J.; Carson, R.H.; Fitchett, J.; Lee, C.; Cole, D. J. Chrom. A, 1994, 680, 469.
    • (1995) Rapid Commun. Mass Spectrom. , vol.9 , pp. 97
    • Greig, M.1    Griffey, R.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.