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Volumn 124, Issue 1-2, 1996, Pages 87-94

Neurochemical evidence for antagonism by olanzapine of dopamine, serotonin, α1-adrenergic and muscarinic receptors in vivo in rats

Author keywords

Atypical antipsychotic; Dopamine; Dopamine antagonist; Muscarinic; Olanzapine; Serotonin

Indexed keywords

2 ETHOXY 1(2H) QUINOLINECARBOXYLIC ACID ETHYL ESTER; 3 HYDROXYBENZYLHYDRAZINE; 3 O METHYLDOPAMINE; 3,4 DIHYDROXYPHENYLACETIC ACID; 4 HYDROXY 3 METHOXYPHENYLETHYLENE GLYCOL SULFATE; 8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; ACETYLCHOLINE; ALPHA 1 ADRENERGIC RECEPTOR; DOPA; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; DOPAMINE AUTORECEPTOR; DOPAMINE RECEPTOR; GAMMA BUTYROLACTONE; HOMOVANILLIC ACID; KETANSERIN; MUSCARINIC RECEPTOR; NEUROLEPTIC AGENT; NOMIFENSINE; OLANZAPINE; PERGOLIDE; PIRENZEPINE; QUIPAZINE; RADIOLIGAND; SEROTONIN 2 RECEPTOR; SEROTONIN RECEPTOR; SPIPERONE;

EID: 0029880065     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02245608     Document Type: Article
Times cited : (138)

References (47)
  • 3
    • 0030065502 scopus 로고    scopus 로고
    • Olanzapine versus placebo and haloperidol: Acute phase results of the North American double blind olanzapine trial
    • Beasley CM, Tollefson GD, Tran P, Satterlee W, Sanger T, Holman S and the olanzapine HGAD Study Group (1996) Olanzapine versus placebo and haloperidol: acute phase results of the North American double blind olanzapine trial. Neuropsychopharmacology 14: 111-123
    • (1996) Neuropsychopharmacology , vol.14 , pp. 111-123
    • Beasley, C.M.1    Tollefson, G.D.2    Tran, P.3    Satterlee, W.4    Sanger, T.5    Holman, S.6
  • 4
    • 0029073180 scopus 로고
    • Olanzapine increases rates of punished responding in pigeons
    • Benvenga MJ, Leander JD (1995) Olanzapine increases rates of punished responding in pigeons. Psychopharmacology 119: 133-138
    • (1995) Psychopharmacology , vol.119 , pp. 133-138
    • Benvenga, M.J.1    Leander, J.D.2
  • 5
    • 0027361997 scopus 로고
    • Comparative behavioral and neurochemical activities of cholinergic antagonists in rats
    • Bymaster FP, Heath I, Hendrix JC, Shannon HE (1993) Comparative behavioral and neurochemical activities of cholinergic antagonists in rats. J Pharmacol Exp Ther 267: 16-24
    • (1993) J Pharmacol Exp Ther , vol.267 , pp. 16-24
    • Bymaster, F.P.1    Heath, I.2    Hendrix, J.C.3    Shannon, H.E.4
  • 7
    • 0020576408 scopus 로고
    • Typical and atypical neuroleptics: Differential effects of chronic administration on the activity of A9 and A10 midbrain dopaminergic neurons
    • Chiodo LA, Bunney BS (1983) Typical and atypical neuroleptics: differential effects of chronic administration on the activity of A9 and A10 midbrain dopaminergic neurons. J Neurosci 3: 1607-1619
    • (1983) J Neurosci , vol.3 , pp. 1607-1619
    • Chiodo, L.A.1    Bunney, B.S.2
  • 8
    • 0023005971 scopus 로고
    • 2 receptors: Implications for drug mechanism of action
    • 2 receptors: implications for drug mechanism of action. Life Sci 39: 2571-2580
    • (1986) Life Sci , vol.39 , pp. 2571-2580
    • Cohen, B.M.1    Lipinski, J.F.2
  • 9
    • 0017255979 scopus 로고
    • Dopamine receptor binding predicts clinical and pharmacological potencies of antischizophrenic drugs
    • Creese I, Burt DR, Snyder SH (1976) Dopamine receptor binding predicts clinical and pharmacological potencies of antischizophrenic drugs. Science 192: 481-483
    • (1976) Science , vol.192 , pp. 481-483
    • Creese, I.1    Burt, D.R.2    Snyder, S.H.3
  • 10
    • 0018840421 scopus 로고
    • Accumulation of L-dopa in the median eminence: An index of tuberoinfundibular dopaminergic nerve activity
    • Demarest KT, Moore KE (1980) Accumulation of L-dopa in the median eminence: an index of tuberoinfundibular dopaminergic nerve activity. Endocrinology 106: 463-468
    • (1980) Endocrinology , vol.106 , pp. 463-468
    • Demarest, K.T.1    Moore, K.E.2
  • 11
    • 0024560609 scopus 로고
    • Effects of buspirone and its metabolite, 1-(2-pyrimidinyl)piperazine, on brain monoamines and their metabolites in rats
    • Fuller RW, Perry KW (1989) Effects of buspirone and its metabolite, 1-(2-pyrimidinyl)piperazine, on brain monoamines and their metabolites in rats. J Pharmacol Exp Ther 248: 50-56
    • (1989) J Pharmacol Exp Ther , vol.248 , pp. 50-56
    • Fuller, R.W.1    Perry, K.W.2
  • 12
    • 0026651080 scopus 로고
    • Neuroendocrine evidence for antagonism of serotonin and dopamine receptors by olanzapine, an antipsychotic drug candidate
    • Fuller RW, Snoddy HD (1992) Neuroendocrine evidence for antagonism of serotonin and dopamine receptors by olanzapine, an antipsychotic drug candidate. Res Comm Chem Pathol Pharmacol 77: 87-93
    • (1992) Res Comm Chem Pathol Pharmacol , vol.77 , pp. 87-93
    • Fuller, R.W.1    Snoddy, H.D.2
  • 13
    • 0017843014 scopus 로고
    • Effect of prazosin on norepinephrine concentration and turnover in rat brain and heart
    • Fuller RW, Snoddy HD, Perry KW (1978) Effect of prazosin on norepinephrine concentration and turnover in rat brain and heart. Arch Int Pharmacodyn Ther 231: 30-41
    • (1978) Arch Int Pharmacodyn Ther , vol.231 , pp. 30-41
    • Fuller, R.W.1    Snoddy, H.D.2    Perry, K.W.3
  • 14
    • 0018333268 scopus 로고
    • Effect of (8β)-8-[(methylthio)methyl]-6-propylergoline on dopaminergic function and brain dopamine turnover in rats
    • Fuller RW, Clemens JA, Kornfeld ED, Snoddy HD, Smalstig EB, Bach NJ (1979) Effect of (8β)-8-[(methylthio)methyl]-6-propylergoline on dopaminergic function and brain dopamine turnover in rats. Life Sci 24: 375-382
    • (1979) Life Sci , vol.24 , pp. 375-382
    • Fuller, R.W.1    Clemens, J.A.2    Kornfeld, E.D.3    Snoddy, H.D.4    Smalstig, E.B.5    Bach, N.J.6
  • 16
    • 0025245752 scopus 로고
    • A new and highly sensitive method for measuring 3-methoxytyramine using HPLC with electrochemical detection. Studies with drugs which alter dopamine metabolism in the brain
    • Heal DJ, Frankland ATJ, Buckett WR (1990) A new and highly sensitive method for measuring 3-methoxytyramine using HPLC with electrochemical detection. Studies with drugs which alter dopamine metabolism in the brain. Neuropharmacology 29: 1141-1150
    • (1990) Neuropharmacology , vol.29 , pp. 1141-1150
    • Heal, D.J.1    Frankland, A.T.J.2    Buckett, W.R.3
  • 18
    • 0028206468 scopus 로고
    • Evaluation of nefazodone as a serotonin uptake inhibitor and a serotonin antagonist in vivo
    • Hemrick-Luecke SK, Snoddy HD, Fuller RW (1994) Evaluation of nefazodone as a serotonin uptake inhibitor and a serotonin antagonist in vivo. Life Sci 55: 479-483
    • (1994) Life Sci , vol.55 , pp. 479-483
    • Hemrick-Luecke, S.K.1    Snoddy, H.D.2    Fuller, R.W.3
  • 19
    • 0021966825 scopus 로고
    • On the presence in the cerebral cortex of muscarinic receptor subtypes which differ in neuronal localization, function and pharmacological properties
    • Marchi M, Raiteri M (1985) On the presence in the cerebral cortex of muscarinic receptor subtypes which differ in neuronal localization, function and pharmacological properties. J Pharmacol Exp Ther 235: 230-233
    • (1985) J Pharmacol Exp Ther , vol.235 , pp. 230-233
    • Marchi, M.1    Raiteri, M.2
  • 20
    • 0019935003 scopus 로고
    • A pharmacologic comparison of 6,7-dihydroxy-2-dimethylaminotetralin (TL-99) and N-n-propyl-3-(3-hydroxyphenyl)piperidine with (3-PPP) selected dopamine agonists
    • Martin GE, Williams M, Haubrich DR (1982) A pharmacologic comparison of 6,7-dihydroxy-2-dimethylaminotetralin (TL-99) and N-n-propyl-3-(3-hydroxyphenyl)piperidine with (3-PPP) selected dopamine agonists. J Pharmacol Exp Ther 223: 298-304
    • (1982) J Pharmacol Exp Ther , vol.223 , pp. 298-304
    • Martin, G.E.1    Williams, M.2    Haubrich, D.R.3
  • 21
    • 0016140107 scopus 로고
    • Influence of noncholinergic drugs on rat striatal acetylcholine levels
    • McGeer PL, Grewaal DS, McGeer EG (1974) Influence of noncholinergic drugs on rat striatal acetylcholine levels. Brain Res 80: 211-217
    • (1974) Brain Res , vol.80 , pp. 211-217
    • McGeer, P.L.1    Grewaal, D.S.2    McGeer, E.G.3
  • 22
    • 0027381650 scopus 로고
    • Pharmacological characterization of the rat hippocampal autoreceptor
    • McKinney M, Miller JH, Aagaard PJ (1993) Pharmacological characterization of the rat hippocampal autoreceptor. J Pharmacol Exp Ther 264: 74-78
    • (1993) J Pharmacol Exp Ther , vol.264 , pp. 74-78
    • McKinney, M.1    Miller, J.H.2    Aagaard, P.J.3
  • 23
    • 0018225681 scopus 로고
    • Comparative effects of clozapine and α-adrenergic blocking drugs on regional noradrenaline metabolism in rat brain
    • McMillen BA, Shore P (1978) Comparative effects of clozapine and α-adrenergic blocking drugs on regional noradrenaline metabolism in rat brain. Eur J Pharmacol 52: 225-230
    • (1978) Eur J Pharmacol , vol.52 , pp. 225-230
    • McMillen, B.A.1    Shore, P.2
  • 24
    • 0015597721 scopus 로고
    • The rate of formation of 3-methoxy-4-hydroxyphenylethyleneglycol sulfate in brain as an estimate of the rate of formation of norepinephrine
    • Meek JL, Neff NH (1973) The rate of formation of 3-methoxy-4-hydroxyphenylethyleneglycol sulfate in brain as an estimate of the rate of formation of norepinephrine. J Pharmacol Exp Ther 184: 570-575
    • (1973) J Pharmacol Exp Ther , vol.184 , pp. 570-575
    • Meek, J.L.1    Neff, N.H.2
  • 25
    • 0021893269 scopus 로고
    • 2 dopamine receptors by N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline in vivo: Selective protection by neuroleptics
    • 2 dopamine receptors by N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline in vivo: selective protection by neuroleptics. J Pharmacol Exp Ther 233: 656-662
    • (1985) J Pharmacol Exp Ther , vol.233 , pp. 656-662
    • Meller, E.1    Bohmaker, K.2    Goldstein, M.3    Friedhoff, A.J.4
  • 26
    • 0024466603 scopus 로고
    • Classification of typical and atypical antipsychotic drugs on the basis of dopamine D-1, D-2 and serotonin2 pKi values
    • Meltzer HY, Matsubara S, Lee J-C (1989) Classification of typical and atypical antipsychotic drugs on the basis of dopamine D-1, D-2 and serotonin2 pKi values. J Pharmacol Exp Ther 251: 238-246
    • (1989) J Pharmacol Exp Ther , vol.251 , pp. 238-246
    • Meltzer, H.Y.1    Matsubara, S.2    Lee, J.-C.3
  • 27
    • 0016332289 scopus 로고
    • Anti-muscarinic properties of neuroleptics and drug-induced parkinsonism
    • Miller RJ, Hiley CR (1974) Anti-muscarinic properties of neuroleptics and drug-induced parkinsonism. Nature 248: 596-597
    • (1974) Nature , vol.248 , pp. 596-597
    • Miller, R.J.1    Hiley, C.R.2
  • 28
    • 0026757929 scopus 로고
    • The behavioral pharmacology of olanzapine a novel "atypical" antipsychotic agent
    • Moore NA, Tye NC, Axton MS, Risius FC (1992) The behavioral pharmacology of olanzapine a novel "atypical" antipsychotic agent. J Pharmacol Exp Ther 262: 545-551
    • (1992) J Pharmacol Exp Ther , vol.262 , pp. 545-551
    • Moore, N.A.1    Tye, N.C.2    Axton, M.S.3    Risius, F.C.4
  • 30
    • 0028301260 scopus 로고
    • Effect of olanzapine and other antipsychotic agents on responding maintained by a conflict schedule
    • Moore NA, Rees G, Sanger G, Tye NC (1994) Effect of olanzapine and other antipsychotic agents on responding maintained by a conflict schedule. Behav Pharmacol 5: 196-202
    • (1994) Behav Pharmacol , vol.5 , pp. 196-202
    • Moore, N.A.1    Rees, G.2    Sanger, G.3    Tye, N.C.4
  • 33
    • 9244243547 scopus 로고
    • Serotonergic drugs increase MHPG-SO4 in rat hypothalamus
    • Perry KW, Fuller RW (1991) Serotonergic drugs increase MHPG-SO4 in rat hypothalamus. Soc Neurosci Abstr 17: 1178
    • (1991) Soc Neurosci Abstr , vol.17 , pp. 1178
    • Perry, K.W.1    Fuller, R.W.2
  • 34
    • 0019429841 scopus 로고
    • Chronic treatment with some atypical antidepressants increases the brain level of 3-methoxy-4-hydroxyphenylglycol (MHPG) in rats
    • Przegalinski E, Kordecka-Magiera A, Mogilnicka E, Maj J (1981) Chronic treatment with some atypical antidepressants increases the brain level of 3-methoxy-4-hydroxyphenylglycol (MHPG) in rats. Psychopharmacology 74: 187-190
    • (1981) Psychopharmacology , vol.74 , pp. 187-190
    • Przegalinski, E.1    Kordecka-Magiera, A.2    Mogilnicka, E.3    Maj, J.4
  • 35
    • 0024210281 scopus 로고
    • Potency of antipsychotics in reversing the effects of a hallucinogenic drug on locus coeruleus neurons correlates with 5HT2 binding affinity
    • Rasmussen K, Aghajanian GK (1988) Potency of antipsychotics in reversing the effects of a hallucinogenic drug on locus coeruleus neurons correlates with 5HT2 binding affinity. Neuropsychopharmacology 1: 101-107
    • (1988) Neuropsychopharmacology , vol.1 , pp. 101-107
    • Rasmussen, K.1    Aghajanian, G.K.2
  • 37
    • 0026777391 scopus 로고
    • Metabotropic glutamate receptor activation produces extrapyramidal motor system activation that is mediated by dopamine
    • Sacaan AI, Bymaster FP, Schoepp DD (1992) Metabotropic glutamate receptor activation produces extrapyramidal motor system activation that is mediated by dopamine. J Neurochem 59: 245-251
    • (1992) J Neurochem , vol.59 , pp. 245-251
    • Sacaan, A.I.1    Bymaster, F.P.2    Schoepp, D.D.3
  • 38
    • 0022533114 scopus 로고
    • 3-Methoxytyramine accumulation: Effects of typical neuroleptics and various atypical compounds
    • Saller CF, Salama AI (1986) 3-Methoxytyramine accumulation: effects of typical neuroleptics and various atypical compounds. Naunyn-Schmiedeberg's Arch Pharmacol 334: 125-132
    • (1986) Naunyn-Schmiedeberg's Arch Pharmacol , vol.334 , pp. 125-132
    • Saller, C.F.1    Salama, A.I.2
  • 39
    • 0017068246 scopus 로고
    • Antipsychotic drug doses and neuroleptic/dopamine receptors
    • Seeman P, Lee T, Chang-Wong M, Wong K (1976) Antipsychotic drug doses and neuroleptic/dopamine receptors. Nature 261: 717-718
    • (1976) Nature , vol.261 , pp. 717-718
    • Seeman, P.1    Lee, T.2    Chang-Wong, M.3    Wong, K.4
  • 40
    • 0015865299 scopus 로고
    • Antimuscarinic drugs-effect on brain acetylcholine and tremors in rats
    • Sethy VH, Van Woert MH (1973) Antimuscarinic drugs-effect on brain acetylcholine and tremors in rats. Biochem Pharmacol 22: 2685-2691
    • (1973) Biochem Pharmacol , vol.22 , pp. 2685-2691
    • Sethy, V.H.1    Van Woert, M.H.2
  • 41
    • 0016191890 scopus 로고
    • Modification of striatal acetylcholine concentration by dopamine receptor agonists and antagonists
    • Sethy VH, Van Woert MH (1974) Modification of striatal acetylcholine concentration by dopamine receptor agonists and antagonists. Res Comm Chem Pathol Pharmacol 8: 13-28
    • (1974) Res Comm Chem Pathol Pharmacol , vol.8 , pp. 13-28
    • Sethy, V.H.1    Van Woert, M.H.2
  • 42
    • 0030040463 scopus 로고    scopus 로고
    • Electrophysiological effects of olanzapine, a novel atypical antipsychotic, on A9 and A10 dopamine neurons
    • Stockton ME, Rasmussen K (1996) Electrophysiological effects of olanzapine, a novel atypical antipsychotic, on A9 and A10 dopamine neurons. Neuropsychopharmacology 14: 92-104
    • (1996) Neuropsychopharmacology , vol.14 , pp. 92-104
    • Stockton, M.E.1    Rasmussen, K.2
  • 43
    • 0018379943 scopus 로고
    • Effects of drugs on regional brain concentrations of dopamine and dihydroxyphenylacetic acid
    • Umezu K, Moore KE (1979) Effects of drugs on regional brain concentrations of dopamine and dihydroxyphenylacetic acid. J Pharmacol Exp Ther 208: 49-56
    • (1979) J Pharmacol Exp Ther , vol.208 , pp. 49-56
    • Umezu, K.1    Moore, K.E.2
  • 45
    • 0015692339 scopus 로고
    • Dopaminergic neurons: Similar biochemical and histochemieal effects of γ-hydroxy-butyrate and acute lesions of the nigro-neostriatal pathway
    • Walters JR, Roth RH, Aghajanian GK (1973) Dopaminergic neurons: similar biochemical and histochemieal effects of γ-hydroxy-butyrate and acute lesions of the nigro-neostriatal pathway. J Pharmacol Exp Ther 186: 630-639
    • (1973) J Pharmacol Exp Ther , vol.186 , pp. 630-639
    • Walters, J.R.1    Roth, R.H.2    Aghajanian, G.K.3
  • 46
    • 0021963877 scopus 로고
    • Sequence and significance of dopamine metabolism in the rat brain
    • Westerink BHC (1985) Sequence and significance of dopamine metabolism in the rat brain. Neurochem Int 7: 221-227
    • (1985) Neurochem Int , vol.7 , pp. 221-227
    • Westerink, B.H.C.1
  • 47
    • 0021744159 scopus 로고
    • Effect of neuroleptic drugs on striatal dopamine release and metabolism in the awake rat studied by intracerebral dialysis
    • Zetterstrom T, Sharp T, Ungerstedt U (1985) Effect of neuroleptic drugs on striatal dopamine release and metabolism in the awake rat studied by intracerebral dialysis. Eur J Pharmacol 106:27-37
    • (1985) Eur J Pharmacol , vol.106 , pp. 27-37
    • Zetterstrom, T.1    Sharp, T.2    Ungerstedt, U.3


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