-
1
-
-
0030065502
-
Olanzapine versus placebo and haloperidol: Acute phase results of the North American double-blind olanzapine trial
-
Beasley CM, Tollefson GD, Tran P, Satterlee W, Sanger T, Holman S, HGAD Olanzapine Study Group (1996): Olanzapine versus placebo and haloperidol: Acute phase results of the North American double-blind olanzapine trial. Neuropsychopharmacology 14:111-123
-
(1996)
Neuropsychopharmacology
, vol.14
, pp. 111-123
-
-
Beasley, C.M.1
Tollefson, G.D.2
Tran, P.3
Satterlee, W.4
Sanger, T.5
Holman, S.6
-
2
-
-
0030062260
-
Radioreceptor binding profile of the atypical antipsychotic olanzapine
-
Bymaster FP, Calligaro DO, Falcone JF, Marsh RD, Moore ND, Tye NC, Seeman P, Wong DT (1996): Radioreceptor binding profile of the atypical antipsychotic olanzapine. Neuropsychopharmacology 14:87-96
-
(1996)
Neuropsychopharmacology
, vol.14
, pp. 87-96
-
-
Bymaster, F.P.1
Calligaro, D.O.2
Falcone, J.F.3
Marsh, R.D.4
Moore, N.D.5
Tye, N.C.6
Seeman, P.7
Wong, D.T.8
-
3
-
-
0026602564
-
Clozapine: A hypothesized mechanism for its unique clinical profile
-
Bunney BS (1992): Clozapine: A hypothesized mechanism for its unique clinical profile. Br J Psychiatry 160(suppl. 17):17-21
-
(1992)
Br J Psychiatry
, vol.160
, Issue.SUPPL. 17
, pp. 17-21
-
-
Bunney, B.S.1
-
4
-
-
0016133738
-
A comparison of the effects of chlorpromazine, 7-hydroxychlorpromazine and chlorpromazine sulfoxide on the activity of central dopaminergic neurons
-
Bunney BS, Aghajanian GK (1974) : A comparison of the effects of chlorpromazine, 7-hydroxychlorpromazine and chlorpromazine sulfoxide on the activity of central dopaminergic neurons. Life Sci 15:309-318
-
(1974)
Life Sci
, vol.15
, pp. 309-318
-
-
Bunney, B.S.1
Aghajanian, G.K.2
-
5
-
-
0010668220
-
Antipsychotic drugs and central dopaminergic neurons: A model for predicting therapeutic efficacy and incidence of extrapyramidal side effects
-
Sudilovsky A, Gershon S, Beer B (eds), New York, Raven
-
Bunney BS, Aghajanian GK (1975): Antipsychotic drugs and central dopaminergic neurons: A model for predicting therapeutic efficacy and incidence of extrapyramidal side effects. In Sudilovsky A, Gershon S, Beer B (eds), Predictability in Psychopharmacology: Preclinical and Clinical Correlations, New York, Raven, pp 225-245
-
(1975)
Predictability in Psychopharmacology: Preclinical and Clinical Correlations
, pp. 225-245
-
-
Bunney, B.S.1
Aghajanian, G.K.2
-
6
-
-
0018116725
-
Acute and chronic haloperidol treatment: Comparison of effects on nigral dopaminergic cell activity
-
Bunney BS, Grace AA (1978): Acute and chronic haloperidol treatment: Comparison of effects on nigral dopaminergic cell activity. Life Sci 23:1715-1728
-
(1978)
Life Sci
, vol.23
, pp. 1715-1728
-
-
Bunney, B.S.1
Grace, A.A.2
-
7
-
-
0015742027
-
Dopaminergic neurons: Effects of antipsychotic drugs and amphetamine on single cell activity
-
Bunney BS, Walters JR, Roth RH, Aghajanian GK (1973): Dopaminergic neurons: Effects of antipsychotic drugs and amphetamine on single cell activity. J Pharm Exp Ther 185:560-571
-
(1973)
J Pharm Exp Ther
, vol.185
, pp. 560-571
-
-
Bunney, B.S.1
Walters, J.R.2
Roth, R.H.3
Aghajanian, G.K.4
-
8
-
-
0020576408
-
Typical and atypical neuroleptics: Differential effects of chronic administration on the activity of A9 and A10 midbrain dopaminergic neurons
-
Chiodo LA, Bunney BS (1983): Typical and atypical neuroleptics: Differential effects of chronic administration on the activity of A9 and A10 midbrain dopaminergic neurons. J Neurosci 3:1607-1619
-
(1983)
J Neurosci
, vol.3
, pp. 1607-1619
-
-
Chiodo, L.A.1
Bunney, B.S.2
-
9
-
-
0023484475
-
The risks and benefits of clozapine versus chlorpromazine
-
Claghorn J, Honigfeld G, Abuzzahab FS Sr, Wang R, Steinbock R, Tuason V, Klerman G (1987): The risks and benefits of clozapine versus chlorpromazine. J Psychopharmacol 7:377-384
-
(1987)
J Psychopharmacol
, vol.7
, pp. 377-384
-
-
Claghorn, J.1
Honigfeld, G.2
Abuzzahab F.S., Sr.3
Wang, R.4
Steinbock, R.5
Tuason, V.6
Klerman, G.7
-
10
-
-
0017255979
-
Dopamine receptor binding predicts clinical and pharmacological potencies of antischizophrenic drugs
-
Creese I, Burt DR, Snyder SH (1976): Dopamine receptor binding predicts clinical and pharmacological potencies of antischizophrenic drugs. Science 192:481-483
-
(1976)
Science
, vol.192
, pp. 481-483
-
-
Creese, I.1
Burt, D.R.2
Snyder, S.H.3
-
11
-
-
0026070134
-
Dopamine in schizophrenia: A review and reconceptualization
-
Davis KL, Kahn RS, Ko G, Davidson M (1991): Dopamine in schizophrenia: A review and reconceptualization. Am J Psychiatry 148:1474-1486
-
(1991)
Am J Psychiatry
, vol.148
, pp. 1474-1486
-
-
Davis, K.L.1
Kahn, R.S.2
Ko, G.3
Davidson, M.4
-
13
-
-
0027264147
-
Prefrontal cortical dopamine systems and the elaboration of functional corticostriatal circuits: Implications for schizophrenia and Parkinson's disease
-
Deutch AY (1993): Prefrontal cortical dopamine systems and the elaboration of functional corticostriatal circuits: Implications for schizophrenia and Parkinson's disease. J Neural Transm [GenSect] 91:197-221
-
(1993)
J Neural Transm [GenSect]
, vol.91
, pp. 197-221
-
-
Deutch, A.Y.1
-
14
-
-
0024498230
-
The effect of acute and chronic treatment with SCH23390 on the spontaneous activity of midbrain dopamine neurons
-
Esposito E, Bunney BS (1988): The effect of acute and chronic treatment with SCH23390 on the spontaneous activity of midbrain dopamine neurons. Eur J Pharmacol 162: 109-113
-
(1988)
Eur J Pharmacol
, vol.162
, pp. 109-113
-
-
Esposito, E.1
Bunney, B.S.2
-
16
-
-
0026651080
-
Neuroendocrine evidence for antagonism of serotonin and dopamine receptors by olanzapine (LY170053), an antipsychotic drug candidate
-
Fuller RW, Snoddy HD (1992): Neuroendocrine evidence for antagonism of serotonin and dopamine receptors by olanzapine (LY170053), an antipsychotic drug candidate. Res Comm Chem Path Pharm 77:87-93
-
(1992)
Res Comm Chem Path Pharm
, vol.77
, pp. 87-93
-
-
Fuller, R.W.1
Snoddy, H.D.2
-
17
-
-
0028211481
-
BMY 14802, a sigma receptor ligand for the treatment of schizophrenia
-
Gewirtz GR, Forman JM, Volavka J, Macaluso J, Gribkoff G, Taylor DP, Borison J (1994): BMY 14802, a sigma receptor ligand for the treatment of schizophrenia. Neuropsychopharm 10:37-40
-
(1994)
Neuropsychopharm
, vol.10
, pp. 37-40
-
-
Gewirtz, G.R.1
Forman, J.M.2
Volavka, J.3
Macaluso, J.4
Gribkoff, G.5
Taylor, D.P.6
Borison, J.7
-
18
-
-
0023690611
-
Spontaneous activity of A9 and A10 dopamine neurons after acute and chronic administration of the selective dopamine D-1 receptor antagonist SCH23390
-
Goldstein JM, and Litwin LC (1988a): Spontaneous activity of A9 and A10 dopamine neurons after acute and chronic administration of the selective dopamine D-1 receptor antagonist SCH23390. Eur J Pharmacol 155:175-180
-
(1988)
Eur J Pharmacol
, vol.155
, pp. 175-180
-
-
Goldstein, J.M.1
Litwin, L.C.2
-
19
-
-
0007831386
-
Antipsychotic-like activity of ritanserin following chronic treatment in rats
-
Goldstein JM, Litwin LC (1988b): Antipsychotic-like activity of ritanserin following chronic treatment in rats. FASEB 2:A1404
-
(1988)
FASEB
, vol.2
-
-
Goldstein, J.M.1
Litwin, L.C.2
-
22
-
-
0026059697
-
Phasic versus tonic release and the modulation of dopamine system responsivity: A hypothesis for the etiology of schizophrenia
-
Grace AA (1919): Phasic versus tonic release and the modulation of dopamine system responsivity: A hypothesis for the etiology of schizophrenia. Neurosci 41:1-24
-
(1919)
Neurosci
, vol.41
, pp. 1-24
-
-
Grace, A.A.1
-
23
-
-
0026611393
-
The depolarization block hypothesis of neuroleptic action: Implications for the etiology and treatment of schizophrenia
-
Grace AA (1992): The depolarization block hypothesis of neuroleptic action: Implications for the etiology and treatment of schizophrenia. J Neural Transm 36:91-131
-
(1992)
J Neural Transm
, vol.36
, pp. 91-131
-
-
Grace, A.A.1
-
24
-
-
0016842979
-
Clozapine and agranulocytosis
-
Griffith RW, Saameli K (1975): Clozapine and agranulocytosis. Lancet 2:657
-
(1975)
Lancet
, vol.2
, pp. 657
-
-
Griffith, R.W.1
Saameli, K.2
-
25
-
-
0027524707
-
Improvement in cognitive functions and psychiatric symptoms in treatment-refractory schizophrenic patients receiving clozapine
-
Hagger C, Buckley P, Kenny JT, Friedman L, Ubogy D, Meltzer HY (1993): Improvement in cognitive functions and psychiatric symptoms in treatment-refractory schizophrenic patients receiving clozapine. Biol Psychiatry 34: 702-712
-
(1993)
Biol Psychiatry
, vol.34
, pp. 702-712
-
-
Hagger, C.1
Buckley, P.2
Kenny, J.T.3
Friedman, L.4
Ubogy, D.5
Meltzer, H.Y.6
-
26
-
-
0027251133
-
The dopamine hypothesis of schizophrenia: Limbic interactions with serotonin and norepinephrine
-
Joyce JN (1993): The dopamine hypothesis of schizophrenia: Limbic interactions with serotonin and norepinephrine. Psychopharmacology 112:S16-S34
-
(1993)
Psychopharmacology
, vol.112
-
-
Joyce, J.N.1
-
27
-
-
0021962263
-
Tolerability and therapeutic effect of clozapine: A retrospective investigation of 216 patients treated with clozapine for up to 12 years
-
Juul Povlsen U, Noring U, Fog R, Gerlach J (1985): Tolerability and therapeutic effect of clozapine: A retrospective investigation of 216 patients treated with clozapine for up to 12 years. Acta Psychiatr Scand 71:176-185
-
(1985)
Acta Psychiatr Scand
, vol.71
, pp. 176-185
-
-
Juul Povlsen, U.1
Noring, U.2
Fog, R.3
Gerlach, J.4
-
28
-
-
0023812652
-
Clozapine for the treatment-resistant schizophrenic: A double-blind comparison with chlorpromazine
-
Kane J, Honigfeld G, Singer J, Meltzer HY, the Clozaril Collaborative Study Group (1988): Clozapine for the treatment-resistant schizophrenic: A double-blind comparison with chlorpromazine. Arch Gen Psychiatry 45:789-796
-
(1988)
Arch Gen Psychiatry
, vol.45
, pp. 789-796
-
-
Kane, J.1
Honigfeld, G.2
Singer, J.3
Meltzer, H.Y.4
-
29
-
-
0023801345
-
Clozapine induced agranulocytosis: Non-cross reactivity with psychotropic drugs
-
Lieberman JA, Johns CA, Kane JM, Rai K, Pisciotta AV, Saltz DL, Howard A (1988): Clozapine induced agranulocytosis: Non-cross reactivity with psychotropic drugs. J Clin Psychiatry 49:271-277
-
(1988)
J Clin Psychiatry
, vol.49
, pp. 271-277
-
-
Lieberman, J.A.1
Johns, C.A.2
Kane, J.M.3
Rai, K.4
Pisciotta, A.V.5
Saltz, D.L.6
Howard, A.7
-
30
-
-
0002728247
-
The dopamine hypothesis of schizophrenia
-
Meltzer HY (ed), New York, Raven
-
Losonczy MF, Davidson M, Davis KL (1987): The dopamine hypothesis of schizophrenia. In Meltzer HY (ed), Psychopharmacology: The third generation of progress, New York, Raven, pp 715-726
-
(1987)
Psychopharmacology: The Third Generation of Progress
, pp. 715-726
-
-
Losonczy, M.F.1
Davidson, M.2
Davis, K.L.3
-
33
-
-
0026091799
-
The mechanism of action of novel antipsychotic drugs
-
Meltzer HY (1991): The mechanism of action of novel antipsychotic drugs. Schizophrenia Bull 17:263-287
-
(1991)
Schizophrenia Bull
, vol.17
, pp. 263-287
-
-
Meltzer, H.Y.1
-
34
-
-
0024443178
-
A prospective study of clozapine in treatment-resistant schizophrenic patients. 1. Preliminary report
-
Meltzer HY, Bastani B, Kwon B, Ramirez L, Burnett S, Shapre J (1989): A prospective study of clozapine in treatment-resistant schizophrenic patients. 1. Preliminary report. Psychopharmacology 99(suppl):S68-S72
-
(1989)
Psychopharmacology
, vol.99
, Issue.SUPPL.
-
-
Meltzer, H.Y.1
Bastani, B.2
Kwon, B.3
Ramirez, L.4
Burnett, S.5
Shapre, J.6
-
35
-
-
0028044565
-
Clozapine's effect on negative symptoms in treatment-refractory schizophrenics
-
Miller DD, Perry PJ, Cadoret RJ, Andreasen NC (1994): Clozapine's effect on negative symptoms in treatment-refractory schizophrenics. Compr Psychiat 35:8-15
-
(1994)
Compr Psychiat
, vol.35
, pp. 8-15
-
-
Miller, D.D.1
Perry, P.J.2
Cadoret, R.J.3
Andreasen, N.C.4
-
36
-
-
0025786633
-
3 receptor antagonist, on the number of spontaneously active midbrain dopamine neurons
-
3 receptor antagonist, on the number of spontaneously active midbrain dopamine neurons. Eur J Pharmacol 209:151-156
-
(1991)
Eur J Pharmacol
, vol.209
, pp. 151-156
-
-
Minabe, Y.1
Ashby, C.R.2
Wang, R.Y.3
-
37
-
-
0026870987
-
Effects produced by acute and chronic treatment with granisetron alone or in combination with haloperidol on midbrain dopamine neurons
-
Minabe Y, Ashby CR, Wang RY (1992): Effects produced by acute and chronic treatment with granisetron alone or in combination with haloperidol on midbrain dopamine neurons. Eur Neuropsychopharm 2:127-133
-
(1992)
Eur Neuropsychopharm
, vol.2
, pp. 127-133
-
-
Minabe, Y.1
Ashby, C.R.2
Wang, R.Y.3
-
38
-
-
0027283733
-
Depolarization inactivation of dopamine neurons. Terminal release characteristics
-
Moghaddam B, Bunney BS (1993): Depolarization inactivation of dopamine neurons. Terminal release characteristics. Synapse 14:195-200
-
(1993)
Synapse
, vol.14
, pp. 195-200
-
-
Moghaddam, B.1
Bunney, B.S.2
-
39
-
-
0026757929
-
The behavioral pharmacology of olanzapine, a novel "atypical" antipsychotic agent
-
Moore NA, Tye NC, Axton MS, Risius F (1992): The behavioral pharmacology of olanzapine, a novel "atypical" antipsychotic agent. J Pharmacol Exp Ther 262:545-551
-
(1992)
J Pharmacol Exp Ther
, vol.262
, pp. 545-551
-
-
Moore, N.A.1
Tye, N.C.2
Axton, M.S.3
Risius, F.4
-
42
-
-
0026582009
-
3 receptor antagonist, causes a selective decrease in the number of spontaneously active dopaminergic neurons in the rat ventral tegmental area
-
3 receptor antagonist, causes a selective decrease in the number of spontaneously active dopaminergic neurons in the rat ventral tegmental area. Eur J Pharmacol 214:13-19
-
(1991)
Eur J Pharmacol
, vol.214
, pp. 13-19
-
-
Prisco, S.1
Pessia, M.2
Ceci, A.3
Borsini, F.4
Esposito, E.5
-
43
-
-
0025918709
-
3 receptor antagonist zatosetron decreases the number of spontaneously active A10 dopamine neurons
-
3 receptor antagonist zatosetron decreases the number of spontaneously active A10 dopamine neurons. Eur J Pharmacol 205:113-116
-
(1991)
Eur J Pharmacol
, vol.205
, pp. 113-116
-
-
Rasmussen, K.1
Stockton, M.E.2
Czachura, J.F.3
-
44
-
-
0026086596
-
Cholecystokinin (CCK) and schizophrenia: The selective CCK-B antagonist LY262691 decreases midbrain dopamine unit activity
-
Rasmussen K, Stockton ME, Czachura JF, Howbert JJ (1991b): Cholecystokinin (CCK) and schizophrenia: The selective CCK-B antagonist LY262691 decreases midbrain dopamine unit activity. Eur J Pharm 209:135-138
-
(1991)
Eur J Pharm
, vol.209
, pp. 135-138
-
-
Rasmussen, K.1
Stockton, M.E.2
Czachura, J.F.3
Howbert, J.J.4
-
45
-
-
0028261434
-
Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors
-
Roth BL Craigo SC, Choudhary MS, Uluer A, Monsma FJ, Shen Y, Meltzer HY, Sibley DR (1994): Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors. J Pharm Exp Ther 268:1403-1410
-
(1994)
J Pharm Exp Ther
, vol.268
, pp. 1403-1410
-
-
Roth, B.L.1
Craigo, S.C.2
Choudhary, M.S.3
Uluer, A.4
Monsma, F.J.5
Shen, Y.6
Meltzer, H.Y.7
Sibley, D.R.8
-
47
-
-
0027439069
-
Schizophrenia as a brain disease: The dopamine receptor story
-
Seeman P (1993): Schizophrenia as a brain disease: The dopamine receptor story. Arch Neurol 50:1093-1095
-
(1993)
Arch Neurol
, vol.50
, pp. 1093-1095
-
-
Seeman, P.1
-
48
-
-
0010686493
-
Brain receptors for antipsychotic drugs and dopamine: Direct binding assays
-
Seeman P, Chau-Wong M, Tedesco J, Wong K (1975): Brain receptors for antipsychotic drugs and dopamine: Direct binding assays. Proc Natl Acad Sci USA 72:4376-4380
-
(1975)
Proc Natl Acad Sci USA
, vol.72
, pp. 4376-4380
-
-
Seeman, P.1
Chau-Wong, M.2
Tedesco, J.3
Wong, K.4
-
49
-
-
0023864292
-
Effect of chronic treatment with SCH23390 and haloperidol on spontaneous activity of dopamine neurons in substantia nigra pars compacta (SNc) and ventral tegmental area (VTA) in rats
-
Skarsfeldt T (1988a): Effect of chronic treatment with SCH23390 and haloperidol on spontaneous activity of dopamine neurons in substantia nigra pars compacta (SNc) and ventral tegmental area (VTA) in rats. Eur J Pharmacol 145:239-243
-
(1988)
Eur J Pharmacol
, vol.145
, pp. 239-243
-
-
Skarsfeldt, T.1
-
50
-
-
0023873613
-
Differential effects after repeated treatment with haloperidol, clozapine, thioridazine and tefludazine on SNc and VTA dopamine neurons in rats
-
Skarsfeldt T (1988b). Differential effects after repeated treatment with haloperidol, clozapine, thioridazine and tefludazine on SNc and VTA dopamine neurons in rats. Life Sci 42:1037-1044
-
(1988)
Life Sci
, vol.42
, pp. 1037-1044
-
-
Skarsfeldt, T.1
-
51
-
-
0026571852
-
Electrophysiological profile of the new atypical neuroleptic, sertindole, on midbrain dopamine neurons in rats: Acute and repeated treatment
-
Skarsfeldt T (1992): Electrophysiological profile of the new atypical neuroleptic, sertindole, on midbrain dopamine neurons in rats: Acute and repeated treatment. Synapse 10:25-33
-
(1992)
Synapse
, vol.10
, pp. 25-33
-
-
Skarsfeldt, T.1
-
52
-
-
0027226187
-
Comparison of the effect of substituted benzamides on midbrain dopamine neurons after treatment of rats for 21 days
-
Skarsfeldt T (1993): Comparison of the effect of substituted benzamides on midbrain dopamine neurons after treatment of rats for 21 days. Eur J Pharmacol 240:269-275
-
(1993)
Eur J Pharmacol
, vol.240
, pp. 269-275
-
-
Skarsfeldt, T.1
-
55
-
-
0023877507
-
Electrophysiological effects of BMY14802, a new potential antipsychotic drug, on midbrain dopamine neurons in the rat: Acute and chronic studies
-
Wachtel SR, White FJ (1988): Electrophysiological effects of BMY14802, a new potential antipsychotic drug, on midbrain dopamine neurons in the rat: Acute and chronic studies. J Pharmacol Exp Ther 244:410-416
-
(1988)
J Pharmacol Exp Ther
, vol.244
, pp. 410-416
-
-
Wachtel, S.R.1
White, F.J.2
-
56
-
-
0026576084
-
The effect of continuous and repeated administration of Di dopamine receptor antagonist on midbrain dopamine neurons
-
Watchtel SR, White FJ (1992): The effect of continuous and repeated administration of Di dopamine receptor antagonist on midbrain dopamine neurons. Neurochem Int 20:129S-133S
-
(1992)
Neurochem Int
, vol.20
-
-
Watchtel, S.R.1
White, F.J.2
-
57
-
-
0023215296
-
Implications of normal brain development for the pathogenesis of schizophrenia
-
Weinberger DR (1987): Implications of normal brain development for the pathogenesis of schizophrenia. Arch Gen Psych 44:660-669
-
(1987)
Arch Gen Psych
, vol.44
, pp. 660-669
-
-
Weinberger, D.R.1
-
58
-
-
0020637803
-
Differential effects of classical and atypical antipsychotic drugs on A9 and A10 dopamine neurons
-
White FJ, Wang RY (1983): Differential effects of classical and atypical antipsychotic drugs on A9 and A10 dopamine neurons. Science 221:1054-1057
-
(1983)
Science
, vol.221
, pp. 1054-1057
-
-
White, F.J.1
Wang, R.Y.2
|