-
1
-
-
0009689979
-
Drug resistance. new approaches to treatment
-
P Chandra (ed.), Plenum Press, New York
-
BERINO, J.R., SRIMATKANDADA, S., CARMAN, M.D., JASTREBOFF, M., MEHIMAN L., MEDINA, W.D., MINI, E., MOROSON, B.A., CASHMORE, A R and DUBE, S.K., Drug resistance. new approaches to treatment. In P Chandra (ed.), New experimental modalities in the control of neoplasia. pp. 183-193, Plenum Press, New York (1986).
-
(1986)
New Experimental Modalities in the Control of Neoplasia
, pp. 183-193
-
-
Berino, J.R.1
Srimatkandada, S.2
Carman, M.D.3
Jastreboff, M.4
Mehiman, L.5
Medina, W.D.6
Mini, E.7
Moroson, B.A.8
Cashmore, A.R.9
Dube, S.K.10
-
2
-
-
0026576765
-
The synthesis and thymidylate-synthase-inhibiton, activity of the poly-γ-glutamyl conjugates of ICI D1694 and other quinazoline anti-folates
-
BISSEI, G.M.F., PAWELCZAK, K., JACKMAN, A.L., CALVERT, A.H. and HUGHES L.R., The synthesis and thymidylate-synthase-inhibiton, activity of the poly-γ-glutamyl conjugates of ICI D1694 and other quinazoline anti-folates. J. med. Chem., 35, 859-866 (1992).
-
(1992)
J. Med. Chem.
, vol.35
, pp. 859-866
-
-
Bissei, G.M.F.1
Pawelczak, K.2
Jackman, A.L.3
Calvert, A.H.4
Hughes, L.R.5
-
3
-
-
0018876308
-
Quinazoline antifolates with dual biochemical loci of action. Biochemical and biological studies directed towards overcoming methotrexate resistance
-
CALVERT, A.H., JONES, T.R., DADY, P.J., GRZELAKOWSKA-SZTABERT, B., PAINE, R.M., TAYLOR, G.A. and HARRAP, K.R., Quinazoline antifolates with dual biochemical loci of action. Biochemical and biological studies directed towards overcoming methotrexate resistance. Europ J. Cancer. 16, 713-722 (1980).
-
(1980)
Europ J. Cancer
, vol.16
, pp. 713-722
-
-
Calvert, A.H.1
Jones, T.R.2
Dady, P.J.3
Grzelakowska-Sztabert, B.4
Paine, R.M.5
Taylor, G.A.6
Harrap, K.R.7
-
4
-
-
0022410582
-
Polyslutamation of methotrexate
-
CHABNER, B.A., ALLEGRA, C.J., CURT, G.A., CLENDENIN, N.J., BARAM, J., KOIZUMI, S., DRAKE, J.C and JOLIVET, J., Polyslutamation of methotrexate. J. clin. Invest., 76, 907-912 (1985).
-
(1985)
J. Clin. Invest.
, vol.76
, pp. 907-912
-
-
Chabner, B.A.1
Allegra, C.J.2
Curt, G.A.3
Clendenin, N.J.4
Baram, J.5
Koizumi, S.6
Drake, J.C.7
Jolivet, J.8
-
5
-
-
0026516892
-
One-hour downward alkaline capillary transfer for blotting of DNA and RNA
-
CHOMCZYNSKI, P., One-hour downward alkaline capillary transfer for blotting of DNA and RNA. Anal. Biochem., 201, 134-139 (1992).
-
(1992)
Anal. Biochem.
, vol.201
, pp. 134-139
-
-
Chomczynski, P.1
-
6
-
-
0023277545
-
Single-step method of RNA isolation by acid-guanidinium-thiocyanate-phenol-chloroform extraction
-
CHOMCZYNSKI, P. and SACCHI, N., Single-step method of RNA isolation by acid-guanidinium-thiocyanate-phenol-chloroform extraction. Anal. Biochem., 162, 156-159 (1987).
-
(1987)
Anal. Biochem.
, vol.162
, pp. 156-159
-
-
Chomczynski, P.1
Sacchi, N.2
-
7
-
-
0018874761
-
Evidence for the cytotoxic activity of polyglutamate derivatives of methotrexate
-
GALIVAN, J., Evidence for the cytotoxic activity of polyglutamate derivatives of methotrexate, Mol. Pharmacol., 17, 105-110 (1980).
-
(1980)
Mol. Pharmacol.
, vol.17
, pp. 105-110
-
-
Galivan, J.1
-
8
-
-
0026686811
-
Expression cloning of a human cDNA encoding folylpoly(γ-glutamate) synthetase and determination of its primary structure
-
GARROW, T.A., ADMON, A. and SHANE, B., Expression cloning of a human cDNA encoding folylpoly(γ-glutamate) synthetase and determination of its primary structure. Proc. nat. Acad, Sci. (Wash.), 89, 9151-9155 (1992).
-
(1992)
Proc. Nat. Acad, Sci. (Wash.)
, vol.89
, pp. 9151-9155
-
-
Garrow, T.A.1
Admon, A.2
Shane, B.3
-
9
-
-
0027502819
-
The measurement of polyglut0amate metabolites of the thymidylate-synthase inhibitor. ICI D1694. in mouse and human cultured cells
-
GIBSON, W., BISSET, G.M.F., MARSHAM, P.R., KELLAND, L.R., JUDSON, I.R. and JACKMAN, A.L., The measurement of polyglut0amate metabolites of the thymidylate-synthase inhibitor. ICI D1694. in mouse and human cultured cells. Biochem. Pharmacol., 45, 863-869 (1993).
-
(1993)
Biochem. Pharmacol.
, vol.45
, pp. 863-869
-
-
Gibson, W.1
Bisset, G.M.F.2
Marsham, P.R.3
Kelland, L.R.4
Judson, I.R.5
Jackman, A.L.6
-
10
-
-
0022500826
-
10-propargyl-5.8-dideazafolic acid (CB3717): Development, characterization, and cross-resistance studies
-
10-propargyl-5.8-dideazafolic acid (CB3717): development, characterization, and cross-resistance studies. Cancer Res., 46, 2810-2815 (1986).
-
(1986)
Cancer Res.
, vol.46
, pp. 2810-2815
-
-
Jackman, A.L.1
Alison, D.L.2
Calvert, A.H.3
Harrap, K.R.4
-
11
-
-
0029031286
-
Mechanisms of acquired resistance to the quinazoline thymidylate-synthase inhibitor ZD1694 (Tomudex) in one mouse and three human cell lines
-
JACKMAN, A.L., KELLAND, L.R., KIMBELL, R., BROWN, M., GIBSON, W., AHERNE, G.W., HARDCASTLE, A. and BOYLE, T., Mechanisms of acquired resistance to the quinazoline thymidylate-synthase inhibitor ZD1694 (Tomudex) in one mouse and three human cell lines. Bru. J. Cancer, 71, 914-924 (1995).
-
(1995)
Bru. J. Cancer
, vol.71
, pp. 914-924
-
-
Jackman, A.L.1
Kelland, L.R.2
Kimbell, R.3
Brown, M.4
Gibson, W.5
Aherne, G.W.6
Hardcastle, A.7
Boyle, T.8
-
12
-
-
0026054878
-
10-substituted-5.8-dideazafolates
-
10-substituted-5.8-dideazafolates. Advanc. Enzyme Regul., 31, 13-27 (1991b).
-
(1991)
Advanc. Enzyme Regul.
, vol.31
, pp. 13-27
-
-
Jackman, A.L.1
Marsham, P.R.2
Moran, R.G.3
Kimbell, R.4
O'Connor, B.M.5
Hughes, L.R.6
Calvert, A.H.7
-
13
-
-
0025997350
-
ICI D1694. a quinazoline anti-folate thymidylate-synthase inhibitor that is a potent inhibitor of L1210 tumor-cell growth in vitro and in vivo: A new agent for clinical study
-
JACKMAN, A.L., TAYLOR, G.A., GIBSON, W., KIMBELL, R., BROWN, M., CALVERT, A.H., JUDSON, I.R. and HUGHES, L.R., ICI D1694. a quinazoline anti-folate thymidylate-synthase inhibitor that is a potent inhibitor of L1210 tumor-cell growth in vitro and in vivo: a new agent for clinical study. Cancer Res., 51, 5579-5586 (1991a).
-
(1991)
Cancer Res.
, vol.51
, pp. 5579-5586
-
-
Jackman, A.L.1
Taylor, G.A.2
Gibson, W.3
Kimbell, R.4
Brown, M.5
Calvert, A.H.6
Judson, I.R.7
Hughes, L.R.8
-
14
-
-
0017112240
-
Intrinsic resistance to methotrexate of cultured mammalian cells in relation to the inhibition kinetics of their dihydrofolate reductases
-
JACKSON, R.C., HART, L.I. and HARRAP, K.R., Intrinsic resistance to methotrexate of cultured mammalian cells in relation to the inhibition kinetics of their dihydrofolate reductases. Cancer Res., 36, 1991-1997 (1976).
-
(1976)
Cancer Res.
, vol.36
, pp. 1991-1997
-
-
Jackson, R.C.1
Hart, L.I.2
Harrap, K.R.3
-
15
-
-
0022491590
-
Folate requirements of methotrexate-resistant human acute-lymphoblastic-leukemia cell lines
-
KANO, Y., OHNUMA, T. and HOLLAND, J.F., Folate requirements of methotrexate-resistant human acute-lymphoblastic-leukemia cell lines. Blood, 68, 586-591 (1986).
-
(1986)
Blood
, vol.68
, pp. 586-591
-
-
Kano, Y.1
Ohnuma, T.2
Holland, J.F.3
-
16
-
-
0027378870
-
Increased activity of γ-glutamyl hydrolase in human sarcoma cell lines: A novel mechanism of intrinsic resistance to methotrexate
-
J.E. Ayling, M.G. Nair and C.M. Baugh (eds.), Advanc. Exp. Med. Biol., Plenum Press, New York
-
Li, W.W., WALTHAM, M., TONG, W., SCHWEITZER, B.I. and BERTINO, J.R., Increased activity of γ-glutamyl hydrolase in human sarcoma cell lines: a novel mechanism of intrinsic resistance to methotrexate. In: J.E. Ayling, M.G. Nair and C.M. Baugh (eds.), Chemistry and biology of pteridines and folates. Advanc. Exp. Med. Biol., 338, pp. 635-638, Plenum Press, New York (1993).
-
(1993)
Chemistry and Biology of Pteridines and Folates
, vol.338
, pp. 635-638
-
-
Li, W.W.1
Waltham, M.2
Tong, W.3
Schweitzer, B.I.4
Bertino, J.R.5
-
17
-
-
0025817134
-
Decreased folylpolyglutamate-synthetase activity as a mechanism of methotrexate resistance in CCRF-CEM human leukemia sub-lines
-
MCCLOSKEY, D.E., MCGUIRE, J.J., RUSSELL, C.A., ROWAN, B.G., BERTINO, J R., PIZZORNO, G. and MINI, E., Decreased folylpolyglutamate-synthetase activity as a mechanism of methotrexate resistance in CCRF-CEM human leukemia sub-lines. J. biol. Chem., 266, 6181-6187 (1991).
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 6181-6187
-
-
Mccloskey, D.E.1
Mcguire, J.J.2
Russell, C.A.3
Rowan, B.G.4
Bertino, J.R.5
Pizzorno, G.6
Mini, E.7
-
18
-
-
0015394127
-
Rosette-forming human lymphoid cell lines: I. Establishment and evidence for origin of thymus-derived lymphocytes
-
MINOWADA, J., OHNUMA, T. and MOORE, G.E., Rosette-forming human lymphoid cell lines: I. Establishment and evidence for origin of thymus-derived lymphocytes. J nat. Cancer Inst., 49, 891-895 (1972).
-
(1972)
J Nat. Cancer Inst.
, vol.49
, pp. 891-895
-
-
Minowada, J.1
Ohnuma, T.2
Moore, G.E.3
-
19
-
-
0028895532
-
Expression of variant dihydrofolate reductase with decreased binding affinity to anti-folates in MOLT-3 human leukemia cell lines resistant to trimetrexate
-
MIYACHI, H., TAKEMURA, Y., KOBAYASHI, H. and ANDO, Y., Expression of variant dihydrofolate reductase with decreased binding affinity to anti-folates in MOLT-3 human leukemia cell lines resistant to trimetrexate. Cancer Lett., 88, 93-99 (1995).
-
(1995)
Cancer Lett.
, vol.88
, pp. 93-99
-
-
Miyachi, H.1
Takemura, Y.2
Kobayashi, H.3
Ando, Y.4
-
20
-
-
0026549002
-
10-propargyl-5.8-dideazafolic acid: A novel folate-based thymidylate-synthase inhibitor
-
10-propargyl-5.8-dideazafolic acid: a novel folate-based thymidylate-synthase inhibitor. Cancer Res., 52, 1137-1143 (1992).
-
(1992)
Cancer Res.
, vol.52
, pp. 1137-1143
-
-
O'Connor, B.M.1
Jackman, A.L.2
Crossley, P.H.3
Freemantle, S.E.4
Lunec, J.5
Calvert, A.H.6
-
21
-
-
0021844160
-
Evolution of methotrexate resistance of human acute lymphoblastic leukemia cells in vitro
-
OHNUMA, T., LO, R.J., SCANLON, K.J., KAMEN, B.A., OHNOSHI, T., WOLMAN, S.R. and HOLLAND, J.F., Evolution of methotrexate resistance of human acute lymphoblastic leukemia cells in vitro. Cancer Res., 45, 1815-1822 (1985).
-
(1985)
Cancer Res.
, vol.45
, pp. 1815-1822
-
-
Ohnuma, T.1
Lo, R.J.2
Scanlon, K.J.3
Kamen, B.A.4
Ohnoshi, T.5
Wolman, S.R.6
Holland, J.F.7
-
22
-
-
0023935785
-
Impaired polyglutamylation of methotrexate as a cause of resistance in CCRF-CEM cells after short-term, high-dose treatment with this drug
-
PIZZORNO, G., MINI, E., CORONNELLO, M., MCGUIRE, J.J., MOROSON, B.A , CASHMORE, A R., DREYER, R.N., LIN, J.T., MAZZEI, T., PERIE, P. and BERTINO, J.R., Impaired polyglutamylation of methotrexate as a cause of resistance in CCRF-CEM cells after short-term, high-dose treatment with this drug. Cancer Res.. 48, 2149-2155 (1988).
-
(1988)
Cancer Res.
, vol.48
, pp. 2149-2155
-
-
Pizzorno, G.1
Mini, E.2
Coronnello, M.3
Mcguire, J.J.4
Moroson, B.A.5
Cashmore, A.R.6
Dreyer, R.N.7
Lin, J.T.8
Mazzei, T.9
Perie, P.10
Bertino, J.R.11
-
23
-
-
0027222801
-
Acquisition of resistance to antifolates caused by enhanced γ-glutamyl hydrolase activity
-
RHEE, M.S., WANG, Y., NAIR, M.G. and GALIVAN, J., Acquisition of resistance to antifolates caused by enhanced γ-glutamyl hydrolase activity. Cancer Res . 53, 2227-2230 (1993).
-
(1993)
Cancer Res .
, vol.53
, pp. 2227-2230
-
-
Rhee, M.S.1
Wang, Y.2
Nair, M.G.3
Galivan, J.4
-
24
-
-
0020030888
-
Biochemical correlates of responsiveness and collateral sensitivity of some methotrexate-resistant murine tumors to the lipophilic antifolate. metoprine
-
SIROTNAK, P.M., MOCCIO, D.M., GOUTAS, L.J., KELLEHER, L.E. and MONTGOMERY, J.A., Biochemical correlates of responsiveness and collateral sensitivity of some methotrexate-resistant murine tumors to the lipophilic antifolate. metoprine. Cancer Res.. 42, 924-930 (1982).
-
(1982)
Cancer Res.
, vol.42
, pp. 924-930
-
-
Sirotnak, P.M.1
Moccio, D.M.2
Goutas, L.J.3
Kelleher, L.E.4
Montgomery, J.A.5
-
25
-
-
0030046343
-
Cellular pharmacokinetics of ZD1694 in cultured human leukaemia cells sensitive, or made resistant, to this drug
-
TAKEMURA, Y., GIBSON, W., KIMBELL, R., KOBAYASHI, H., MIYACHI, H. and JACKMAN, A.L., Cellular pharmacokinetics of ZD1694 in cultured human leukaemia cells sensitive, or made resistant, to this drug. J. Cancer Res. clin. Oncol., 122, 109-117 (1996).
-
(1996)
J. Cancer Res. Clin. Oncol.
, vol.122
, pp. 109-117
-
-
Takemura, Y.1
Gibson, W.2
Kimbell, R.3
Kobayashi, H.4
Miyachi, H.5
Jackman, A.L.6
-
26
-
-
0026015930
-
The influence of tumor cell density on cellular accumulation of doxorubicin or cisplatin in vitro
-
TAKEMURA, Y., KOBAYASHI, H., MIYACHI, H., HAYASHI, K., SEKIGUCHI, S. and OHNUMA, T., The influence of tumor cell density on cellular accumulation of doxorubicin or cisplatin in vitro. Cancer Chemother Pharmacol., 27, 417-422 (1991).
-
(1991)
Cancer Chemother Pharmacol.
, vol.27
, pp. 417-422
-
-
Takemura, Y.1
Kobayashi, H.2
Miyachi, H.3
Hayashi, K.4
Sekiguchi, S.5
Ohnuma, T.6
-
27
-
-
0021978533
-
Biologic and pharmacologic effects of harringtonine on human leukemia-lymphoma cells
-
TAKEMURA, Y., OHNUMA, T., CHOU, T.C., OKANO, T. and HOLLAND, J.F., Biologic and pharmacologic effects of harringtonine on human leukemia-lymphoma cells. Cancer Chemother, Pharmacol., 14, 206-210 (1985).
-
(1985)
Cancer Chemother, Pharmacol.
, vol.14
, pp. 206-210
-
-
Takemura, Y.1
Ohnuma, T.2
Chou, T.C.3
Okano, T.4
Holland, J.F.5
-
28
-
-
2242439960
-
Capillary electrophoresis of methotrexate polyglutamates and its application in evaluation of folylpolyglutamate hydrolase activity
-
TONG, W.P., LIN, S., LI, W.W., WALTHAM, M., GOKER, E. and BERTINO, J.R., Capillary electrophoresis of methotrexate polyglutamates and its application in evaluation of folylpolyglutamate hydrolase activity. Proc. Amer. Ass. Cancer Res., 35, 304 (1994).
-
(1994)
Proc. Amer. Ass. Cancer Res.
, vol.35
, pp. 304
-
-
Tong, W.P.1
Lin, S.2
Li, W.W.3
Waltham, M.4
Goker, E.5
Bertino, J.R.6
-
29
-
-
0026519367
-
Kinetic characteristics of ICI D1694: A quinazoline antifolate which inhibits thymidylate synthase
-
WARD, W.H.J., KIMBELL, R. and JACKMAN, A.L., Kinetic characteristics of ICI D1694: a quinazoline antifolate which inhibits thymidylate synthase. Biochem. Pharmacol., 43, 2029-2031 (1992).
-
(1992)
Biochem. Pharmacol.
, vol.43
, pp. 2029-2031
-
-
Ward, W.H.J.1
Kimbell, R.2
Jackman, A.L.3
|