메뉴 건너뛰기




Volumn 26, Issue 11, 1996, Pages 1131-1141

In vitro and in vivo oxidative biotransformation in the West-African dwarf goat (Caprus hircus aegagrus): Substrate activities and effects of inducers

Author keywords

[No Author keywords available]

Indexed keywords

APOPROTEIN; BETA NAPHTHOFLAVONE; CAFFEINE; CYTOCHROME P450; ISONIAZID; PHENAZONE; PHENOBARBITAL; SULFADIMIDINE; TROLEANDOMYCIN;

EID: 0029860247     PISSN: 00498254     EISSN: None     Source Type: Journal    
DOI: 10.3109/00498259609050258     Document Type: Article
Times cited : (18)

References (42)
  • 1
    • 0023884027 scopus 로고
    • Selective inhibition of drug oxidation after simultaneous administration of two probe drugs, antipyrine and tolbutamide
    • BACK, D. J., TJIA, J., MÖNIG, H., OHNAUS, E. E., and PARK, B. K., 1988, Selective inhibition of drug oxidation after simultaneous administration of two probe drugs, antipyrine and tolbutamide. European Journal of Clinical Pharmacology, 34, 157-163.
    • (1988) European Journal of Clinical Pharmacology , vol.34 , pp. 157-163
    • Back, D.J.1    Tjia, J.2    Mönig, H.3    Ohnaus, E.E.4    Park, B.K.5
  • 2
    • 0026646696 scopus 로고
    • Interspecies variations in caffeine metabolism related to cytochrome P4501A enzymes
    • BERTHOU, F., GUILLOIS, B., RICHE, C., DREANO, Y., JACQZ-AIGRAIN, E., and BEAUNE, P. H., 1992, Interspecies variations in caffeine metabolism related to cytochrome P4501A enzymes. Xenobiotica, 22, 671-680.
    • (1992) Xenobiotica , vol.22 , pp. 671-680
    • Berthou, F.1    Guillois, B.2    Riche, C.3    Dreano, Y.4    Jacqz-Aigrain, E.5    Beaune, P.H.6
  • 3
    • 0024343858 scopus 로고
    • pa (P4501A2), the phenacetin o-deethylase is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines
    • pa (P4501A2), the phenacetin o-deethylase is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines. Proceedings of the National Academy of Sciences, USA, 86, 7696-7700.
    • (1989) Proceedings of the National Academy of Sciences, USA , vol.86 , pp. 7696-7700
    • Butler, M.A.1    Iwasaki, M.2    Guengerich, F.P.3    Kadlubar, F.K.4
  • 4
    • 0015341509 scopus 로고
    • A comparative study of two procedures used in the determination of hepatic microsomal aniline hydroxylation
    • CHHABRA, R. S., GRAM, T. E., and FOUTS, J. R., 1972, A comparative study of two procedures used in the determination of hepatic microsomal aniline hydroxylation. Toxicology and Applied Pharmacology, 22, 50-58.
    • (1972) Toxicology and Applied Pharmacology , vol.22 , pp. 50-58
    • Chhabra, R.S.1    Gram, T.E.2    Fouts, J.R.3
  • 5
    • 0021261819 scopus 로고
    • Comparative metabolism of tolbutamide by isolated hepatocytes from rat, rabbit, dog and squirrel monkey
    • GEE, S. J., GREEN, C. E., and TYSON, C. A., 1984, Comparative metabolism of tolbutamide by isolated hepatocytes from rat, rabbit, dog and squirrel monkey. Drug Metabolism and Disposition, 12, 174-178.
    • (1984) Drug Metabolism and Disposition , vol.12 , pp. 174-178
    • Gee, S.J.1    Green, C.E.2    Tyson, C.A.3
  • 7
    • 0026353141 scopus 로고
    • High-performance liquid chromatographic assay of debrisoquine and its 4-hydroxy metabolite in human urine
    • GOUBIER, C., GIRARD, I., and FERRY, S., 1991, High-performance liquid chromatographic assay of debrisoquine and its 4-hydroxy metabolite in human urine. Chromatographia, 32, 523-526.
    • (1991) Chromatographia , vol.32 , pp. 523-526
    • Goubier, C.1    Girard, I.2    Ferry, S.3
  • 9
    • 0013958297 scopus 로고
    • Evidence for biochemically different types of vesicles in the hepatic microsomal fraction
    • IMAI, Y., ITO, A., and SATO, R., 1966, Evidence for biochemically different types of vesicles in the hepatic microsomal fraction. Journal of Biochemistry, 60, 417-428.
    • (1966) Journal of Biochemistry , vol.60 , pp. 417-428
    • Imai, Y.1    Ito, A.2    Sato, R.3
  • 10
    • 0018760985 scopus 로고
    • Characteristics and differences in the hepatic mixed function oxidases of different species
    • KATO, R., 1979, Characteristics and differences in the hepatic mixed function oxidases of different species. Pharmacology and Therapeutics, 6, 41-98.
    • (1979) Pharmacology and Therapeutics , vol.6 , pp. 41-98
    • Kato, R.1
  • 11
    • 0027390703 scopus 로고
    • Hepatic cytochrome P450 induction in goats: Effects of model inducers on the metabolism of alkoxyresorufins, testosterone end ethylmorphine, and on apoprotein and mRNA levels
    • KLOOSTER VAN 'T, G. A. E., HORBACH, G. J. M. J., NATSUHORI, M., BLAAUBOER, B. J., NOORDHOEK, J., and MIERT VAN, A. S. J. P. A. M., 1993, Hepatic cytochrome P450 induction in goats: effects of model inducers on the metabolism of alkoxyresorufins, testosterone end ethylmorphine, and on apoprotein and mRNA levels. Biochemical Pharmacology, 45, 113-122.
    • (1993) Biochemical Pharmacology , vol.45 , pp. 113-122
    • Klooster Van 't, G.A.E.1    Horbach, G.J.M.J.2    Natsuhori, M.3    Blaauboer, B.J.4    Noordhoek, J.5    Miert Van, A.S.J.P.A.M.6
  • 13
    • 0021806780 scopus 로고
    • Immunochemical evidence for induction of the alcohol-oxidizing cytochrome P-450 of rabbit liver microsomes by diverse agents: Ethanol, imidazole, trichloroethylene, acetone, pyrazole, and isoniazid
    • KOOP, D. R., CRUMP, B. L., NORDBLOM, G. D., and COON, M. J., 1985, Immunochemical evidence for induction of the alcohol-oxidizing cytochrome P-450 of rabbit liver microsomes by diverse agents: ethanol, imidazole, trichloroethylene, acetone, pyrazole, and isoniazid. Proceedings of the National Academy of Sciences, USA, 82, 4065-4069.
    • (1985) Proceedings of the National Academy of Sciences, USA , vol.82 , pp. 4065-4069
    • Koop, D.R.1    Crump, B.L.2    Nordblom, G.D.3    Coon, M.J.4
  • 14
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • LAEMMLI, U. K., 1970, Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature, 227, 680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 15
    • 0021236705 scopus 로고
    • Purification and characterization of the rat liver microsomal cytochrome P450 involved in the 4-hydroxylation of debrisoquine, a prototype for genetic variation in oxidative drug metabolism
    • LARREY, D., DISTLERATH, L. M., DANNAN, G. A., WILKINSON, G. R., and GUENGERICH, F. P., 1984, Purification and characterization of the rat liver microsomal cytochrome P450 involved in the 4-hydroxylation of debrisoquine, a prototype for genetic variation in oxidative drug metabolism. Biochemistry, 23, 2787-2795.
    • (1984) Biochemistry , vol.23 , pp. 2787-2795
    • Larrey, D.1    Distlerath, L.M.2    Dannan, G.A.3    Wilkinson, G.R.4    Guengerich, F.P.5
  • 17
    • 0022350885 scopus 로고
    • Dealkylation of pentoxyresorufin : A rapid and sensitive assay for measuring induction of cytochrome(s) P450 by phenobarbital and other xenobiotics in the rat
    • LUBET, R. A., MAYER, R. T., CAMERON, J. W., NIMS, R. W., BURKE, M. D., WOLFE, T., and GUENGERICH, F. P., 1985, Dealkylation of pentoxyresorufin : a rapid and sensitive assay for measuring induction of cytochrome(s) P450 by phenobarbital and other xenobiotics in the rat. Archives of Biochemistry and Biophysics, 238, 43-48.
    • (1985) Archives of Biochemistry and Biophysics , vol.238 , pp. 43-48
    • Lubet, R.A.1    Mayer, R.T.2    Cameron, J.W.3    Nims, R.W.4    Burke, M.D.5    Wolfe, T.6    Guengerich, F.P.7
  • 18
    • 0026519363 scopus 로고
    • Debrisoquine 4-monooxygenase and bufuralol 1′-monooxygenase activities in bovine and rabbit tissues
    • MATSUO, Y. IWAHASHI, K., and ICHIKAWA, Y., 1992, Debrisoquine 4-monooxygenase and bufuralol 1′-monooxygenase activities in bovine and rabbit tissues. Biochemical Pharmacology, 43, 1911-1919.
    • (1992) Biochemical Pharmacology , vol.43 , pp. 1911-1919
    • Matsuo, Y.1    Iwahashi, K.2    Ichikawa, Y.3
  • 20
    • 0025735191 scopus 로고
    • Microsomal cytochrome P450-dependent steroid metabolism in male sheep liver. Quantitative importance of 6β-hydroxylation and evidence for the involvement of a P450 from the IIIA subfamily in the pathway
    • MURRAY, M., 1991, Microsomal cytochrome P450-dependent steroid metabolism in male sheep liver. Quantitative importance of 6β-hydroxylation and evidence for the involvement of a P450 from the IIIA subfamily in the pathway. Journal of Steroid Biochemistry and Molecular Biology, 38, 611-619.
    • (1991) Journal of Steroid Biochemistry and Molecular Biology , vol.38 , pp. 611-619
    • Murray, M.1
  • 21
    • 0038381255 scopus 로고
    • Metabolism of antipyrine and sulphadimidine in dwarf goats: Effects of the enzyme inducing agents phenobarbital, troleandomycin and rifampicin
    • NATSUHORI, M., WITKAMP, R. F., KLOOSTER VAN 'T, G. A. E., and MIERT VAN, A. S. J. P. A. M., 1992, Metabolism of antipyrine and sulphadimidine in dwarf goats: effects of the enzyme inducing agents phenobarbital, troleandomycin and rifampicin. Xenobiotica, 25, 491-199.
    • (1992) Xenobiotica , vol.25 , pp. 491-1199
    • Natsuhori, M.1    Witkamp, R.F.2    Klooster Van 't, G.A.E.3    Miert Van, A.S.J.P.A.M.4
  • 25
    • 0022499774 scopus 로고
    • Evidence that isoniazid and ethanol induce the same microsomal cytochrome P-450 in rat liver, an isozyme homologous to rabbit liver cytochrome P-450 isozyme 3a
    • RYAN, D. E., KOOP, D. R., THOMAS, P. E., COON, M. J., and LEVIN, W., 1986, Evidence that isoniazid and ethanol induce the same microsomal cytochrome P-450 in rat liver, an isozyme homologous to rabbit liver cytochrome P-450 isozyme 3a. Archives of Biochemistry and Biophysics, 246, 663-644.
    • (1986) Archives of Biochemistry and Biophysics , vol.246 , pp. 663-1644
    • Ryan, D.E.1    Koop, D.R.2    Thomas, P.E.3    Coon, M.J.4    Levin, W.5
  • 26
    • 0024370922 scopus 로고
    • Influence of enzyme induction and inhibition on the oxidation of nifedipine, sparteine, mephenytoin and antipyrine in humans as assessed by a 'cocktail' study design
    • SCHELLENS, J. H. M., VAN DER WART, J. H. F., BRUGMAN, M., and BREIMER, D. D., 1989, Influence of enzyme induction and inhibition on the oxidation of nifedipine, sparteine, mephenytoin and antipyrine in humans as assessed by a 'cocktail' study design. Journal of Pharmacology and Experimental Therapeutics, 249, 638-645.
    • (1989) Journal of Pharmacology and Experimental Therapeutics , vol.249 , pp. 638-645
    • Schellens, J.H.M.1    Van Der Wart, J.H.F.2    Brugman, M.3    Breimer, D.D.4
  • 27
    • 0029875703 scopus 로고    scopus 로고
    • Identification of the human hepatic cytochromes P450 involved in the in vitro oxidation of antipyrine
    • SHARER, J. A. and WRIGHTON, S. A., 1996, Identification of the human hepatic cytochromes P450 involved in the in vitro oxidation of antipyrine. Drug Metabolism and Disposition, 24, 487-494.
    • (1996) Drug Metabolism and Disposition , vol.24 , pp. 487-494
    • Sharer, J.A.1    Wrighton, S.A.2
  • 28
    • 0029584297 scopus 로고
    • Age- and sex-related alterations of microsomal drug- and testosterone-oxidizing cytochrome P450 in Sprague-Dawley strain-derived dwarf rats
    • SHIMADA, M. S., MURAYAMA, N., YAMAZOE, Y., HASHIMOTO, H., ISHIKAWA, H., and KATO, R., 1995, Age- and sex-related alterations of microsomal drug- and testosterone-oxidizing cytochrome P450 in Sprague-Dawley strain-derived dwarf rats. Journal of Pharmacology and Experimental Therapeutics, 275, 972-977.
    • (1995) Journal of Pharmacology and Experimental Therapeutics , vol.275 , pp. 972-977
    • Shimada, M.S.1    Murayama, N.2    Yamazoe, Y.3    Hashimoto, H.4    Ishikawa, H.5    Kato, R.6
  • 29
    • 0025772460 scopus 로고
    • Species differences in metabolism and pharmacokinetics: Are we close to understanding?
    • SMITH, D. A., 1991, Species differences in metabolism and pharmacokinetics: are we close to understanding? Drug Metabolism Reviews, 23, 355-373.
    • (1991) Drug Metabolism Reviews , vol.23 , pp. 355-373
    • Smith, D.A.1
  • 31
    • 0009482260 scopus 로고
    • Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
    • TOWBIN, H., STAEHELIN, T., and GORDON, J., 1979, Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proceedings of the National Academy of Sciences, USA, 76, 4350-4354.
    • (1979) Proceedings of the National Academy of Sciences, USA , vol.76 , pp. 4350-4354
    • Towbin, H.1    Staehelin, T.2    Gordon, J.3
  • 34
    • 0028226507 scopus 로고
    • A comparative study of constitutive and induced alkoxyresorufin O-dealkylation and individual cytochrome P450 forms in cynomolgus monkey (Macaca fascicularis), human, mouse, rat and hamster liver microsomes
    • WEAVER, R. J., THOMPSON, S., SMITH, G., DICKINS, M., ELCOMBE, C. R., MAYER, R. T., and BURKE, D., 1994, A comparative study of constitutive and induced alkoxyresorufin O-dealkylation and individual cytochrome P450 forms in cynomolgus monkey (Macaca fascicularis), human, mouse, rat and hamster liver microsomes. Biochemical Pharmacology, 47, 763-773.
    • (1994) Biochemical Pharmacology , vol.47 , pp. 763-773
    • Weaver, R.J.1    Thompson, S.2    Smith, G.3    Dickins, M.4    Elcombe, C.R.5    Mayer, R.T.6    Burke, D.7
  • 36
    • 0026040603 scopus 로고
    • Species- and sex-related differences in the plasma clearance and metabolite formation of antipyrine. A comparative study in four animal species: Cattle, goat, rat and rabbit
    • WITKAMP, R. F., LOHUIS, J. A. C. M., NIJMEIJER, S. M., KOLKER, H. J., NOORDHOEK, J., and MIERT VAN, A. S. J. P. A. M., 1992, Species- and sex-related differences in the plasma clearance and metabolite formation of antipyrine. A comparative study in four animal species: cattle, goat, rat and rabbit. Xenobiotica, 21, 1483-1492.
    • (1992) Xenobiotica , vol.21 , pp. 1483-1492
    • Witkamp, R.F.1    Lohuis, J.A.C.M.2    Nijmeijer, S.M.3    Kolker, H.J.4    Noordhoek, J.5    Miert Van, A.S.J.P.A.M.6
  • 38
    • 0029854216 scopus 로고    scopus 로고
    • Time dependent induction of two distinct hepatic cytochrome P4501A catalytic activities at low temperatures in Arctic charr (Salvelinus alpinus) after oral exposure to benzo(a)pyrene
    • in press
    • WOLKERS, J., JORGENSEN, E. H., NIJMEIJER, S. M., and WITKAMP, R. F., 1996, Time dependent induction of two distinct hepatic cytochrome P4501A catalytic activities at low temperatures in Arctic charr (Salvelinus alpinus) after oral exposure to benzo(a)pyrene. Aquatic Toxicology (in press).
    • (1996) Aquatic Toxicology
    • Wolkers, J.1    Jorgensen, E.H.2    Nijmeijer, S.M.3    Witkamp, R.F.4
  • 39
    • 0025738537 scopus 로고
    • Comparison of cytochrome P450 isoenzyme profiles in rat liver and hepatocyte cultures : The effects of model inducers on apoproteins and biotransformation activities
    • WORTELBOER, H. M., KRUIF DE C. A., IERSEL VAN, A. A. J., FALKE, H. E., NOORDHOEK, J., and BLAAUBOER, B. J., 1991, Comparison of cytochrome P450 isoenzyme profiles in rat liver and hepatocyte cultures : the effects of model inducers on apoproteins and biotransformation activities. Biochemical Pharmacology, 42, 381-390.
    • (1991) Biochemical Pharmacology , vol.42 , pp. 381-390
    • Wortelboer, H.M.1    Kruif De, C.A.2    Iersel Van, A.A.J.3    Falke, H.E.4    Noordhoek, J.5    Blaauboer, B.J.6
  • 40
    • 0025646324 scopus 로고
    • The isoenzyme pattern of cytochrome P450 in rat hepatocytes in primary culture, comparing different enzyme activities in microsomal incubations and in intact monolayers
    • WORTELBOER, H. M., KRUIF DE C. A., IERSEL VAN, A. A. J., FALKE, H. E., NOORDHOEK, J., and BLAAUBOER, B. J., 1990, The isoenzyme pattern of cytochrome P450 in rat hepatocytes in primary culture, comparing different enzyme activities in microsomal incubations and in intact monolayers. Biochemical Pharmacology, 40, 2525-2534.
    • (1990) Biochemical Pharmacology , vol.40 , pp. 2525-2534
    • Wortelboer, H.M.1    Kruif De, C.A.2    Iersel Van, A.A.J.3    Falke, H.E.4    Noordhoek, J.5    Blaauboer, B.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.