Increased telomerase activity in hyperplastic nodules and hepatocellular carcinomas induced by a choline-deficient L-amino acid-defined diet in rats

Japanese Journal of Cancer Research

Volumn 87, Issue 11, 1996, Pages 1111-1115

  Tsujiuchi, Toshifumi ^a   Tsutsumi, Masahiro ^a   Kido, Akira ^a   Kobitsu, Kunihiko ^a   Takahama, Makoto ^a   Majima, Toshimitsu ^a   Denda, Ayumi ^a   Nakae, Dai ^a   Konishi, Yoichi ^a  

^a NARA MEDICAL UNIVERSITY   (Japan)

Author keywords

Choline deficient L amino acid defined diet; Hepatocarcinogenesis; Rat; Telomerase; TRAP assay

Indexed keywords

AMINO ACID; CHOLINE; REPETITIVE DNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIETARY INTAKE; ENZYME ACTIVATION; GENE AMPLIFICATION; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; LIVER HYPERPLASIA; LIVER PARENCHYMA; MALE; NONHUMAN; PRECANCER; PRIORITY JOURNAL; RAT; TELOMERE; VITAMIN DEFICIENCY;

EID: 0029857951     PISSN: 09105050     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1349-7006.1996.tb03119.x     Document Type: Article

References (26)

1. Vogelstein, B., Fearon, E. R., Hamilton, S. R., Kern, S. E., Preisinger, A. C., Leppert, M., Nakamura, Y., Whyte, R., Smits, A. M. M. and Bos, J. L. Genetic alterations during colorectal tumor development. N. Engl. J. Med., 319, 525-532 (1988).
2. Miyaki, T., Seki, M., Okamoto, M., Yamanaka, A., Maeda, Y., Tanaka, K., Kikuchi, R., Iwama, T., Ikeuchi, T., Tonomura, A., Nakamura, Y., White, R., Miki, Y., Utsunomiya, J. and Koike, M. Genetic changes and histopathological types in colorectal tumors from patients with familial adenomatous polyposis. Cancer Res., 50, 7166-7173 (1990).
3. Kim, N. W., Piatyszek, M. A., Prowse, K. R., Harley, C. B., West, M. D., Ho, P. L. C., Coviello, G. H., Wright, W. E., Weinrich, S. L. and Shay, J. W. Specific association of human telomerase activity with immortal cells and cancer. Science, 266, 2011-2015 (1994).
4. Harley, C. B., Andrews, W., Chiu, C.-P., Feng, J., Funk, W., Gaeta, F., Hirsch, K., Kim, N. W., Kozlowski, M., Wang, S.-S., Weinrich, S. L., West, M. D., Avillion, A., Le, S., Greider, C. W. and Villeponteau, B. Human telomerase inhibition and cancer. Proc. Am. Assoc. Cancer Res., 36, 671-672 (1995).
5. Hiyama, K., Hirai, Y., Kyoizumi, S., Akiyama, H., Hiyama, E., Piatyszek, M. A., Shay, J. W., Ishioka, S. and Yamakido, M. Activation of telomerase in human lymphocytes. J. Immunol., 155, 3711-3715 (1995).
6. Taylor, R. S., Ramirez, R. D., Ogushi, M., Chaffins, M., Piatyszek, M. A., Shay, J. W. Detection of telomerase activity in malignant and nonmalignant skin conditions. J. Invest. Dermatol., 106, 759-765 (1996).
7. Hiyama, K., Hiyama, E., Ishioka, S., Yamakido, M., Inai, K., Gazdar, A. F., Piatyszek, M. A. and Shay, J. W. Telomerase activity in small-cell and non- small-cell lung cancers. J. Natl. Cancer Inst., 87, 895-902 (1995).
8. Counter, C. M., Hirte, H. W., Bacchetti, S., Harley, C. B. Telomerase activity in human ovarian carcinoma. Proc. Natl. Acad. Sci. USA, 91, 2900-2904 (1994).
9. Tahara, H., Nakanishi, T., Kitamoto, M., Nakashio, R., Shay, J. W., Tahara, E., Kajiyama, G. and Ide, T. Telomerase activity in human liver tissues: comparison between chronic liver disease and hepatocellular carcinomas. Cancer Res., 55, 2734-2736 (1995).
10. Sommerfeld, H.-J., Meeker, A. K., Piatyszek, M. A., Bova, G. S., Shay, J.W., Coffey, D. S. Telomerase activity: a prevalent marker of malignant human prostate tissue. Cancer Res., 56, 218-222 (1996).
11. Chadeneau, C., Hay, K., Hirte, H. W., Gallinger, S., Bacchetti, S. Telomerase activity associated with acquisition of malignancy in human colorectal cancer. Cancer Res., 55, 2533-2536 (1995).
12. Langford, L. A., Piatyszek, M. A., Xu, R., Schold, S. C. Jr., Shay, J. W. Telomerase activity in human brain tumors. Lancet, 346, 1267-1268 (1995).
13. Bacchetti, S., Counter, C. M., Chadeneau, K. C., Gupta, J., Harley, C. B., Leber, B., Gallinger, S., Hirte, H. W., Siegel, P. and Muller, W. J. Telomerase activity in human and murine somatic tissues and tumors. Proc. Am. Assoc. Cancer Res., 36, 674 (1995).
14. Prowse, K. R., Greider, C. W. Developmental and tissue-specific regulation of mouse telomerase and telomere length. Proc. Natl. Acad. Sci. USA, 92, 4818-4822 (1995).
15. Yoshimi, N., Ino, N., Suzui, M., Hara, A., Nakatani, K., Sato, S. and Mori, H. Telomerase activity of normal tissues and neoplasms in rat colon carcinogenesis induced by methylazoxymethanol acetate and its difference from that of human colonic tissues. Mol. Carcinog., 16, 1-5 (1996).
16. Bednarek, A., Budunova, I., Slaga, T. J., Aldaz, C. M. Increased telomerase activity in mouse skin premalignant progression. Cancer Res., 55, 4566-4569 (1995).
17. Nakae, D., Yoshiji, H., Maruyama, H., Kinugasa, T., Denda, A., Konishi, Y. Production of both 8-hydroxydeoxyguanosine in liver DNA and γ-glutamyltransferase-positive hepatocellular lesions in rats given a choline-deficient, L-amino acid-defined diet. Jpn. J. Cancer Res., 81, 1081-1084 (1990).
18. Nakae, D., Yoshiji, H., Mizumoto, Y., Horiguchi, K., Shiraiwa, K., Tamura, K., Denda, A. and Konishi, Y. High incidence of hepatocellular carcinomas induced by a choline deficient L-amino acid defined diet in rats. Cancer Res., 52, 5042-5045 (1992).
19. Enomoto, K., Farber, E. Kinetics of phenotypic maturation of remodeling of hyperplastic nodules during liver carcinogenesis. Cancer Res., 42, 2330-2335 (1982).
20. Kitagawa, T., Watanabe, R., Kayano, T., Sugano, H. In vitro carcinogenesis of hepatocytes obtained from acetylaminofluorene-treated rat liver and promotion of their growth by phenobarbital. Gann, 71, 747-754 (1980).
21. Counter, C. M., Avilion, A. A., LeFeuvre, C. E., Stewart, N. G., Greider, C. W., Harley, C. B. and Bacchetti, S. Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. EMBO J., 11, 1921-1929 (1992).
22. Harley, C. B., Futcher, A. B., Greider, C. W. Telomeres shorten during aging of human fibroblasts. Nature, 345, 458-460 (1990).
23. Hastie, N. D., Dempster, M. G., Dunlop, M. G., Thompson, A. M., Green, D. K., Allshire, R. C. Telomere reduction in human colorectal carcinoma and with aging. Nature, 346, 866-868 (1990).
24. Mehle, C., Ljungberg, B., Roos, G. Telomere shortening in renal cell carcinoma. Cancer Res., 54, 236-241 (1994).
25. Ohashi, K., Tsutsumi, M., Nakajima, Y., Kobitsu, K., Nakano, H., Konishi, Y. Telomere changes in human hepatocellular carcinomas and hepatitis virus infected non-cancerous liver. Cancer, 77, 1747-1751 (1996).
26. Rhyu, M. S. Telomeres, telomerase, and immortality. J. Natl. Cancer Inst., 87, 884-894 (1995).