-
1
-
-
0026760470
-
Differential inhibition of the epidermal growth factor-, platelet derived growth factor-, and protein kinase C-mediated transduction pathways by the staurosporine derivative CGP 41 251
-
ANDREJAUSKAS-BUCHDUNGER, E., REGENASS, U.: Differential inhibition of the epidermal growth factor-, platelet derived growth factor-, and protein kinase C-mediated transduction pathways by the staurosporine derivative CGP 41 251. Cancer Res., 52, 1992, 5353-5358.
-
(1992)
Cancer Res.
, vol.52
, pp. 5353-5358
-
-
Andrejauskas-Buchdunger, E.1
Regenass, U.2
-
2
-
-
0028874795
-
Apoptosis induced by protein kinase C inhibition in a neuroblastoma cell line
-
BEHRENS, M.M., MARTINEZ, J.L., MORATILLA, C., RENART, J.: Apoptosis induced by protein kinase C inhibition in a neuroblastoma cell line. Cell Growth Differ., 6, 1995, 1373-1380.
-
(1995)
Cell Growth Differ.
, vol.6
, pp. 1373-1380
-
-
Behrens, M.M.1
Martinez, J.L.2
Moratilla, C.3
Renart, J.4
-
3
-
-
10544250925
-
-
Czech Patent 1502, 1977
-
BERÁNEK, J., BROKEŠ, J., HŘEBABECKÝ, H.: Preparation of 1-beta-arabinofuranosylcytosine. Czech Patent 1502, 1977.
-
Preparation of 1-beta-arabinofuranosylcytosine
-
-
Beránek, J.1
Brokeš, J.2
Hřebabecký, H.3
-
4
-
-
0028568630
-
The protein kinase C inhibitor CGP 41 251 reverses decreased daunomycin uptake in a human drug-resistant ovarian carcinoma cell line
-
CHORVÁTH, B., SEDLÁK, J., NOVOTNÝ, L.: The protein kinase C inhibitor CGP 41 251 reverses decreased daunomycin uptake in a human drug-resistant ovarian carcinoma cell line. Int. J. Cancer, 59, 1994, 852-853.
-
(1994)
Int. J. Cancer
, vol.59
, pp. 852-853
-
-
Chorváth, B.1
Sedlák, J.2
Novotný, L.3
-
5
-
-
0029927545
-
Protein kinase inhibitors: Induction of apoptosis and drug resistance modulation in neoplastic cell lines. Minireview
-
CHORVÁTH, B., SEDLÁK, J.: Protein kinase inhibitors: Induction of apoptosis and drug resistance modulation in neoplastic cell lines. Minireview. Neoplasma, 43, 1996, 3-9.
-
(1996)
Neoplasma
, vol.43
, pp. 3-9
-
-
Chorváth, B.1
Sedlák, J.2
-
6
-
-
0021367846
-
Glucocorticoid activation of a calcium-dependent endonuclease in thymocyte model leads to cell death
-
COHEN, J.J., DUKE, R.C.: Glucocorticoid activation of a calcium-dependent endonuclease in thymocyte model leads to cell death. J. Immunol., 132, 1984, 38-42.
-
(1984)
J. Immunol.
, vol.132
, pp. 38-42
-
-
Cohen, J.J.1
Duke, R.C.2
-
7
-
-
0026788002
-
Key morphological features of apoptosis may occur in the absence of internucleosomal DNA fragmentation
-
COHEN, G.M., SUN, X.M., SNOWDEN, R.R., DINSDALE, D., SKILLETER, D.N.: Key morphological features of apoptosis may occur in the absence of internucleosomal DNA fragmentation. Biochem. J., 286, 1992, 331-336.
-
(1992)
Biochem. J.
, vol.286
, pp. 331-336
-
-
Cohen, G.M.1
Sun, X.M.2
Snowden, R.R.3
Dinsdale, D.4
Skilleter, D.N.5
-
8
-
-
0026505081
-
Microfilament disrupting agents prevents the formation of apoptotic bodies in tumor cells undergoing apoptosis
-
COTTER, T.G., LENNON, S.V., CLYNN, J.M., GREEN, D.R.: Microfilament disrupting agents prevents the formation of apoptotic bodies in tumor cells undergoing apoptosis. Cancer Res., 52, 1992, 997-1005.
-
(1992)
Cancer Res.
, vol.52
, pp. 997-1005
-
-
Cotter, T.G.1
Lennon, S.V.2
Clynn, J.M.3
Green, D.R.4
-
9
-
-
0029097704
-
Protective effect of N-acetylcysteine in TNF alpha-induced apoptosis in U-937 cells: The role of mitochondria
-
COSSARIZZA, A., FRANCESCHI, C., MONTI, D., SALVIOLI, S., BELLESIA, E., RIVABENE, R., BIONDO, L., RAINALDI, G., TINARI, A., MALORNI, W.: Protective effect of N-acetylcysteine in TNF alpha-induced apoptosis in U-937 cells: The role of mitochondria. Exp. Cell Res., 220, 1995, 232-240.
-
(1995)
Exp. Cell Res.
, vol.220
, pp. 232-240
-
-
Cossarizza, A.1
Franceschi, C.2
Monti, D.3
Salvioli, S.4
Bellesia, E.5
Rivabene, R.6
Biondo, L.7
Rainaldi, G.8
Tinari, A.9
Malorni, W.10
-
10
-
-
0028175192
-
Tumor necrosis factor-alpha induces apoptosis in human leukemia T cell line MOLT-16: Its relation to bcl-2 and c-myc expression
-
DAO, T., ARIYASU, T., MICALEFF, M., MINOWADA, J.: Tumor necrosis factor-alpha induces apoptosis in human leukemia T cell line MOLT-16: Its relation to bcl-2 and c-myc expression. Int. J. Oncol., 4, 1994, 1471-1475.
-
(1994)
Int. J. Oncol.
, vol.4
, pp. 1471-1475
-
-
Dao, T.1
Ariyasu, T.2
Micaleff, M.3
Minowada, J.4
-
11
-
-
0028898591
-
Flow cytometric determination of apoptosis in heterogenous cell populations
-
DOLZHANSKY, A., BASCH, R.S.: Flow cytometric determination of apoptosis in heterogenous cell populations. J. Immunol. Meth., 180, 1993, 131-140.
-
(1993)
J. Immunol. Meth.
, vol.180
, pp. 131-140
-
-
Dolzhansky, A.1
Basch, R.S.2
-
12
-
-
10544234863
-
Expression of apoptosis-related oncoproteins and modulation of apoptosis by caffeine in human leukemic cells
-
EFFERTH, T., FABRY, U., GLATTE, P., OSIEKA, R.: Expression of apoptosis-related oncoproteins and modulation of apoptosis by caffeine in human leukemic cells. J. Cancer Res. Clin. Oncol., 121, 1955, 468-656.
-
(1955)
J. Cancer Res. Clin. Oncol.
, vol.121
, pp. 468-656
-
-
Efferth, T.1
Fabry, U.2
Glatte, P.3
Osieka, R.4
-
13
-
-
0028294605
-
CIP1 is induced in p53-mediated G1 arrest and apoptosis
-
CIP1 is induced in p53-mediated G1 arrest and apoptosis. Cancer Res., 54, 1994, 1169-1174.
-
(1994)
Cancer Res.
, vol.54
, pp. 1169-1174
-
-
El-Deiry, W.S.1
Harper, J.W.2
O'Connor, P.M.3
Velculescu, P.E.4
Jackman, J.5
Pietenpol, J.A.6
Burrell, M.7
Hill, D.E.8
Wang, Y.9
-
14
-
-
0028025563
-
Apoptosis in cancer therapy: Crossing the threshold
-
FISHER, D.E.: Apoptosis in cancer therapy: Crossing the threshold. Cell, 78, 1994, 539-542.
-
(1994)
Cell
, vol.78
, pp. 539-542
-
-
Fisher, D.E.1
-
15
-
-
0029115973
-
Taxol cytotoxicity on human leukemia cell lines is a function of their susceptibility to programmed cell death
-
GANGEMI, R.M.R., TISO, M., MARCHETTI, C., BARGELLESI, M., SEVERI, A., FABBI, M.: Taxol cytotoxicity on human leukemia cell lines is a function of their susceptibility to programmed cell death. Cancer Chemother. Pharmacol., 36, 1995, 385-392.
-
(1995)
Cancer Chemother. Pharmacol.
, vol.36
, pp. 385-392
-
-
Gangemi, R.M.R.1
Tiso, M.2
Marchetti, C.3
Bargellesi, M.4
Severi, A.5
Fabbi, M.6
-
16
-
-
0010508307
-
The cell cycle-related differences in susceptibility of HL-60 cells to apoptosis induced by various antitumor agents
-
GORCYCZA, W., GONG, J., ARDELT, B., TRAGANOS, F., DARZYNKIEWICZ, Z.: The cell cycle-related differences in susceptibility of HL-60 cells to apoptosis induced by various antitumor agents. Cancer Res., 52, 1992, 6270-6278.
-
(1992)
Cancer Res.
, vol.52
, pp. 6270-6278
-
-
Gorcycza, W.1
Gong, J.2
Ardelt, B.3
Traganos, F.4
Darzynkiewicz, Z.5
-
17
-
-
0028170263
-
Modulation of 1-(beta-D-arabinofuranosyl) cytosine-induced apoptosis in human myeloid leukemia cells by staurosporine and other pharmacological inhibitors of protein kinase C
-
GRANT, S., TURNER, A.J., BARTIMOLE, T.N., NELMS, P.A., JOE, V.C., JARVIS, W.D.: Modulation of 1-(beta-D-arabinofuranosyl) cytosine-induced apoptosis in human myeloid leukemia cells by staurosporine and other pharmacological inhibitors of protein kinase C. Oncol. Res., 6, 1994, 87-99.
-
(1994)
Oncol. Res.
, vol.6
, pp. 87-99
-
-
Grant, S.1
Turner, A.J.2
Bartimole, T.N.3
Nelms, P.A.4
Joe, V.C.5
Jarvis, W.D.6
-
18
-
-
0028980030
-
Deoxy-D-glucose enhances sensitivity of human histiocytic lymphoma U937 cells to apoptosis induced by tumor necrosis factor
-
HALICKA, H.D., ARDELT, B., LI, X., MELAMED, M.M., DARZYNKIEWICZ, Z.: Deoxy-D-glucose enhances sensitivity of human histiocytic lymphoma U937 cells to apoptosis induced by tumor necrosis factor. Cancer Res., 55, 1995, 444-449.
-
(1995)
Cancer Res.
, vol.55
, pp. 444-449
-
-
Halicka, H.D.1
Ardelt, B.2
Li, X.3
Melamed, M.M.4
Darzynkiewicz, Z.5
-
19
-
-
0028783440
-
Induction of apoptosis by gemcitabine
-
HUANG, P., PLUNKETT, W.: Induction of apoptosis by gemcitabine. Semin. Oncol., 22, 1995, 19-25.
-
(1995)
Semin. Oncol.
, vol.22
, pp. 19-25
-
-
Huang, P.1
Plunkett, W.2
-
20
-
-
0028790294
-
Phorbol ester (TPA)-induced differential modulation of cell surface antigens in pluripotential leukemia (K-562) cell line: Effects of protein kinase inhibitors with broad- and PKC-selective inhibitory activity
-
HUNÁKOVÁ, L., SEDLÁK, J., KLOBUŠICKÁ, M., CHORVÁTH, B.: Phorbol ester (TPA)-induced differential modulation of cell surface antigens in pluripotential leukemia (K-562) cell line: Effects of protein kinase inhibitors with broad- and PKC-selective inhibitory activity. Neoplasma, 42, 1995, 249-253.
-
(1995)
Neoplasma
, vol.42
, pp. 249-253
-
-
Hunáková, L.1
Sedlák, J.2
Klobušická, M.3
Chorváth, B.4
-
21
-
-
0028316195
-
Induction of apoptotic DNA fragmentation and cell death in HL-60 human promyelocytic leukemia cells by pharmacological inhibitors of protein kinase C
-
JARVIS, W.D., TURNER, A.J., POVIRK, L.F., TRAYLOR, R.S., GRANT, S.: Induction of apoptotic DNA fragmentation and cell death in HL-60 human promyelocytic leukemia cells by pharmacological inhibitors of protein kinase C. Cancer Res., 54, 1994, 1707-1714.
-
(1994)
Cancer Res.
, vol.54
, pp. 1707-1714
-
-
Jarvis, W.D.1
Turner, A.J.2
Povirk, L.F.3
Traylor, R.S.4
Grant, S.5
-
22
-
-
0029166370
-
Induction of tumor suppressor p21 protein by kinase inhibitors in MCF-7 cells
-
JEOUNG, D.I., TANG, B., SONENBERG, M.: Induction of tumor suppressor p21 protein by kinase inhibitors in MCF-7 cells. Biochem. Biophys. Res. Commun., 214, 1995, 361-366.
-
(1995)
Biochem. Biophys. Res. Commun.
, vol.214
, pp. 361-366
-
-
Jeoung, D.I.1
Tang, B.2
Sonenberg, M.3
-
23
-
-
0028901279
-
Induction of apoptosis by enediyne antitumor antibiotic C1027 in HL-60 human promyelocytic leukemia cells
-
JIANG, B., LI, D.D., ZHEN, Y.: Induction of apoptosis by enediyne antitumor antibiotic C1027 in HL-60 human promyelocytic leukemia cells. Biochem. Biophys. Res. Commun., 208, 1995, 238-244.
-
(1995)
Biochem. Biophys. Res. Commun.
, vol.208
, pp. 238-244
-
-
Jiang, B.1
Li, D.D.2
Zhen, Y.3
-
24
-
-
0027249710
-
The MRP-gene associated with a non-P glycoprotein multidrug resistance encodes a 190 kDa membrane bound glycoprotein
-
KRISHNAMACHARY, N., CENTER, M.S.: The MRP-gene associated with a non-P glycoprotein multidrug resistance encodes a 190 kDa membrane bound glycoprotein. Cancer Res., 53, 1993, 3658-3661.
-
(1993)
Cancer Res.
, vol.53
, pp. 3658-3661
-
-
Krishnamachary, N.1
Center, M.S.2
-
25
-
-
0022458951
-
Isolation and characterization of adriamycin-resistant HL-60 cells which are not defective in the initial accumulation of drug
-
MARSH, W., SICHERI, D., CENTER, M.S.: Isolation and characterization of adriamycin-resistant HL-60 cells which are not defective in the initial accumulation of drug. Cancer Res., 46, 1996, 4053-4057.
-
(1996)
Cancer Res.
, vol.46
, pp. 4053-4057
-
-
Marsh, W.1
Sicheri, D.2
Center, M.S.3
-
26
-
-
0024415437
-
Mechanisms of multidrug resistance in HL-60 cells: Analysis of resistance associated membrane proteins and levels of MDR gene expression
-
MCGRATH, T., LATOUD, C., ARNOLD, S.T., SAFA, A.R., FELSTED, R.L., CENTER, M.S.: Mechanisms of multidrug resistance in HL-60 cells: Analysis of resistance associated membrane proteins and levels of MDR gene expression. Biochem. Pharmacol., 38, 1989, 3611-3619.
-
(1989)
Biochem. Pharmacol.
, vol.38
, pp. 3611-3619
-
-
Mcgrath, T.1
Latoud, C.2
Arnold, S.T.3
Safa, A.R.4
Felsted, R.L.5
Center, M.S.6
-
27
-
-
0024379951
-
A derivative of staurosporine (CGP 41 251) shows selectivity for protein kinase C inhibition and in vitro anti-proliferative as well as in vivo anti-tumor activity
-
MEYER, T., REGENASS, U., FABBRO, D., ALTERI, E., ROSSEL, J., MULLER, M., CARAVATTI, G., MATTER, A.: A derivative of staurosporine (CGP 41 251) shows selectivity for protein kinase C inhibition and in vitro anti-proliferative as well as in vivo anti-tumor activity. Int. J. Cancer, 43, 1989, 851-856.
-
(1989)
Int. J. Cancer
, vol.43
, pp. 851-856
-
-
Meyer, T.1
Regenass, U.2
Fabbro, D.3
Alteri, E.4
Rossel, J.5
Muller, M.6
Caravatti, G.7
Matter, A.8
-
28
-
-
0027217084
-
Apoptotic death in epithelial cells: Cleavage of DNA to 300 and/or 50 kb fragments prior to or in the absence of internucleosomal fragmentation
-
OBERHAMMER, F., WILSON, J.W., DIVE, C., MORRIS, I.D., HICKMAN, J.A., WAKELING, A.E., WALKER, P.R., SIKORSKA, M.: Apoptotic death in epithelial cells: Cleavage of DNA to 300 and/or 50 kb fragments prior to or in the absence of internucleosomal fragmentation. EMBO J., 12, 1993, 3679-3684.
-
(1993)
EMBO J.
, vol.12
, pp. 3679-3684
-
-
Oberhammer, F.1
Wilson, J.W.2
Dive, C.3
Morris, I.D.4
Hickman, J.A.5
Wakeling, A.E.6
Walker, P.R.7
Sikorska, M.8
-
29
-
-
0029046001
-
Changes in protein C isoenzyme expression associated with apoptosis in U937 myelomonocytic cells
-
PONGRACZ, J., TUFFLEY, W., JOHNSON, G.D., DEACON, E.M., BURNETT, D., STOCKLEY, R.A., LORD, J.M.: Changes in protein C isoenzyme expression associated with apoptosis in U937 myelomonocytic cells. Exp. Cell Res., 218, 1995, 430-438.
-
(1995)
Exp. Cell Res.
, vol.218
, pp. 430-438
-
-
Pongracz, J.1
Tuffley, W.2
Johnson, G.D.3
Deacon, E.M.4
Burnett, D.5
Stockley, R.A.6
Lord, J.M.7
-
30
-
-
0028959525
-
Effects of protein kinase C inhibitor, staurosporine derivative CGP 41 251, on cell cycle DNA synthesis and drug uptake in neoplastic cell lines
-
SEDLÁK, J., HUNÁKOVÁ, L., DURAJ, J., CHORVÁTH, B., NOVOTNÝ, L.: Effects of protein kinase C inhibitor, staurosporine derivative CGP 41 251, on cell cycle DNA synthesis and drug uptake in neoplastic cell lines. Anti-Cancer Drugs, 6, 1995, 70-76.
-
(1995)
Anti-Cancer Drugs
, vol.6
, pp. 70-76
-
-
Sedlák, J.1
Hunáková, L.2
Duraj, J.3
Chorváth, B.4
Novotný, L.5
-
31
-
-
0029166239
-
Differential effects of protein kinase inhibitors (staurosporine and CGP 41 251) on TPA-induced homotypic aggregation and cell surface adhesion antigen expression in human monoblastoid U-937 cell line
-
SEDLÁK, J., ŠULIKOVÁ, M., HUNÁKOVÁ, L., CHORVÁTH, B.: Differential effects of protein kinase inhibitors (staurosporine and CGP 41 251) on TPA-induced homotypic aggregation and cell surface adhesion antigen expression in human monoblastoid U-937 cell line. Neoplasma, 42, 1995, 159-165.
-
(1995)
Neoplasma
, vol.42
, pp. 159-165
-
-
Sedlák, J.1
Šuliková, M.2
Hunáková, L.3
Chorváth, B.4
-
32
-
-
0023612470
-
Gene induction by gamma-irradiation leads to DNA fragmentation in lymphocytes
-
SELLINS, K.S., COHEN, J.J.: Gene induction by gamma-irradiation leads to DNA fragmentation in lymphocytes. J. Immunol., 139, 1987, 3199-3206.
-
(1987)
J. Immunol.
, vol.139
, pp. 3199-3206
-
-
Sellins, K.S.1
Cohen, J.J.2
-
33
-
-
0028973212
-
WAF1/CIP1/ induces growth arrest, giant cell formation and apoptosis in human breast carcinoma cell lines
-
WAF1/CIP1/ induces growth arrest, giant cell formation and apoptosis in human breast carcinoma cell lines. Oncogene, 11, 1995, 1899-1908.
-
(1995)
Oncogene
, vol.11
, pp. 1899-1908
-
-
Sheikh, M.S.1
Rochefort, H.2
Garcia, M.3
-
34
-
-
0027448756
-
Caffeine prevents apoptosis and cell cycle effects induced by camptothecin and topotecan in HL-60 cells
-
TRAGANOS, F., KAPUSCINSKI, J., GONG, J., ARDELT, B., DARZYNKIEWICZ, R.J., DARZYNKIEWICZ, Z.: Caffeine prevents apoptosis and cell cycle effects induced by camptothecin and topotecan in HL-60 cells. Cancer Res., 53, 1993, 4613-4618.
-
(1993)
Cancer Res.
, vol.53
, pp. 4613-4618
-
-
Traganos, F.1
Kapuscinski, J.2
Gong, J.3
Ardelt, B.4
Darzynkiewicz, R.J.5
Darzynkiewicz, Z.6
-
35
-
-
0024347970
-
Monoclonal antibody-mediated tumor regression by induction of apoptosis
-
TRAUTH, B.C., KLAS, C., PETERS, A.M.J., MATZKU, S., MOLLER, P., FALK, W., DEBATIN, K.M., KRAMMER, P.H.: Monoclonal antibody-mediated tumor regression by induction of apoptosis. Science, 245, 1989, 301-304.
-
(1989)
Science
, vol.245
, pp. 301-304
-
-
Trauth, B.C.1
Klas, C.2
Peters, A.M.J.3
Matzku, S.4
Moller, P.5
Falk, W.6
Debatin, K.M.7
Krammer, P.H.8
-
36
-
-
0029005530
-
Growth inhibition an apoptosis of RL human B-lymphoma cells by vitamin E succinate and retinoic acid: Role for transforming factor beta
-
TURLEY, J.M., FUNAKOSHI, S., RUSCETT, F.W., KASPER, J., MURPHY, W.J., LONGO, D.L., BIRCHENALL-ROBERTS, M.: Growth inhibition an apoptosis of RL human B-lymphoma cells by vitamin E succinate and retinoic acid: Role for transforming factor beta. Cell Growth Differ., 6, 1995, 655-663.
-
(1995)
Cell Growth Differ.
, vol.6
, pp. 655-663
-
-
Turley, J.M.1
Funakoshi, S.2
Ruscett, F.W.3
Kasper, J.4
Murphy, W.J.5
Longo, D.L.6
Birchenall-Roberts, M.7
-
37
-
-
0028231242
-
The protein kinase inhibitor CGP 41 251, a staurosporine derivative with anti-tumor activity, reverses multidrug resistance
-
UTZ, I., HOFER, S., REGENASS, U., HILBE, E., THALER, J., GRUNICKE, H., HOFMANN, J.: The protein kinase inhibitor CGP 41 251, a staurosporine derivative with anti-tumor activity, reverses multidrug resistance. Int J. Cancer, 57, 1994, 104-110.
-
(1994)
Int J. Cancer
, vol.57
, pp. 104-110
-
-
Utz, I.1
Hofer, S.2
Regenass, U.3
Hilbe, E.4
Thaler, J.5
Grunicke, H.6
Hofmann, J.7
-
38
-
-
0027074965
-
Effects of staurosporine, K252a and other structurally related protein kinase inhibitors on shape and locomotion of Walker carcinosarcoma cells
-
ZIMMERMANN, A., KELLER, H.: Effects of staurosporine, K252a and other structurally related protein kinase inhibitors on shape and locomotion of Walker carcinosarcoma cells. Br. J. Cancer, 66, 1992, 1077-1082.
-
(1992)
Br. J. Cancer
, vol.66
, pp. 1077-1082
-
-
Zimmermann, A.1
Keller, H.2
|