-
1
-
-
0027232037
-
Enhancement of antitumor activity of mitomycin C in vitro and in vivo by UCN-01, a selective inhibitor of protein kinase C
-
AKINAGA, S., NOMURA, K., GOMI, K., OKABE, M.: Enhancement of antitumor activity of mitomycin C in vitro and in vivo by UCN-01, a selective inhibitor of protein kinase C. Cancer Chemother. Pharmacol., 32, 1993, 183-189.
-
(1993)
Cancer Chemother. Pharmacol.
, vol.32
, pp. 183-189
-
-
Akinaga, S.1
Nomura, K.2
Gomi, K.3
Okabe, M.4
-
2
-
-
0027771781
-
Inhibitors of tyrosine phosphorylation induce apoptosis in human leukemic cell lines
-
BERGAMASCHI, G., ROSTI, V., DANOVA, M., PONCHIO, L., LUCOTTI, C., CAZZOLA, M.: Inhibitors of tyrosine phosphorylation induce apoptosis in human leukemic cell lines. Leukemia, 7, 1993, 2012-2018.
-
(1993)
Leukemia
, vol.7
, pp. 2012-2018
-
-
Bergamaschi, G.1
Rosti, V.2
Danova, M.3
Ponchio, L.4
Lucotti, C.5
Cazzola, M.6
-
3
-
-
0027232301
-
Sensitization of tumor cells to tumor necrosis factor action by protein kinase inhibitor staurosporine
-
BEYAERT, R., VANHAESBROEK, B., HEYNINCK, K., BOONE, E., DEVALCK, D., SCHULTZE-OSTHOFF, K., HAEGEMAM, G., VAN ROY, F., FIERS, W.: Sensitization of tumor cells to tumor necrosis factor action by protein kinase inhibitor staurosporine. Cancer Res., 53, 1993, 2623-2630.
-
(1993)
Cancer Res.
, vol.53
, pp. 2623-2630
-
-
Beyaert, R.1
Vanhaesbroek, B.2
Heyninck, K.3
Boone, E.4
Devalck, D.5
Schultze-Osthoff, K.6
Haegemam, G.7
Van Roy, F.8
Fiers, W.9
-
4
-
-
0028107188
-
The phosphoprotein phosphatase calcineurin controls calcium-dependent apoptosis in B cell lines
-
BONNEFOY-BÉRARD, N., GENESTIER, L., FLACHER, N., REVILLARD, J.P.: The phosphoprotein phosphatase calcineurin controls calcium-dependent apoptosis in B cell lines. Eur. J. Immunol., 24, 1994, 325-329.
-
(1994)
Eur. J. Immunol.
, vol.24
, pp. 325-329
-
-
Bonnefoy-Bérard, N.1
Genestier, L.2
Flacher, N.3
Revillard, J.P.4
-
5
-
-
0028170731
-
Down-regulation of Fc receptor IIIA α (CD16-II) on NK cells induced by anti-CD16 MAb is independent of protein tyrosine kinases and protein kinase C
-
BORREGO, F., LOPEZ-BELTRAN, A., PENA, J., SOLANA, R.: Down-regulation of Fc receptor IIIA α (CD16-II) on NK cells induced by anti-CD16 MAb is independent of protein tyrosine kinases and protein kinase C. Cell Immunol., 158, 1994, 208-217.
-
(1994)
Cell Immunol.
, vol.158
, pp. 208-217
-
-
Borrego, F.1
Lopez-Beltran, A.2
Pena, J.3
Solana, R.4
-
6
-
-
0028286135
-
Differential modulation of pharmacologically distinct components of Ca currents by protein kinase C activators and phosphatase inhibitors in nerve-growth-factor-differentiated pheochromocytoma (PC12) cells
-
BOURON, A., REBER, B.F.: Differential modulation of pharmacologically distinct components of Ca currents by protein kinase C activators and phosphatase inhibitors in nerve-growth-factor-differentiated pheochromocytoma (PC12) cells. Pflügers Arch., 427, 1994, 510-516.
-
(1994)
Pflügers Arch.
, vol.427
, pp. 510-516
-
-
Bouron, A.1
Reber, B.F.2
-
7
-
-
0028172837
-
Tyrosine protein kinase inhibitors and cancer
-
BOUTIN, J.: Tyrosine protein kinase inhibitors and cancer. Int. J. Biochem., 26, 1994, 1203-1226.
-
(1994)
Int. J. Biochem.
, vol.26
, pp. 1203-1226
-
-
Boutin, J.1
-
8
-
-
0026501878
-
Different effects of staurosporine, an inhibitor of protein kinases, on the cell cycle and chromatin structure of normal and leukemic lymphocytes
-
BRUNO, S., ARDELT, B., SKIERSKI, S.J., TRAGANOS, F., DARZYNKIEWICZ, Z.: Different effects of staurosporine, an inhibitor of protein kinases, on the cell cycle and chromatin structure of normal and leukemic lymphocytes. Cancer Res., 52, 1992, 470-473.
-
(1992)
Cancer Res.
, vol.52
, pp. 470-473
-
-
Bruno, S.1
Ardelt, B.2
Skierski, S.J.3
Traganos, F.4
Darzynkiewicz, Z.5
-
9
-
-
0027506202
-
Induction of multidrug resistance in human cells by transient exposure to different chemotherapeutic drugs
-
CHAUDHARY, P.M., RONINSON, I.B.: Induction of multidrug resistance in human cells by transient exposure to different chemotherapeutic drugs. J. Natl. Cancer Inst., 85, 1993, 632-639.
-
(1993)
J. Natl. Cancer Inst.
, vol.85
, pp. 632-639
-
-
Chaudhary, P.M.1
Roninson, I.B.2
-
10
-
-
0027076780
-
Regulation by phorbolester and protein kinase C inhibitors and by a protein phosphatase inhibitor (okadaic acid) of P-glycoprotein phosphorylation and relationship to drug accumulation in multidrug-resistant KB cells
-
CHAMBERS, T.C., ZHENG, B., KUO, J.F.: Regulation by phorbolester and protein kinase C inhibitors and by a protein phosphatase inhibitor (okadaic acid) of P-glycoprotein phosphorylation and relationship to drug accumulation in multidrug-resistant KB cells. Mol. Pharmacol., 41, 1992, 1008-1015.
-
(1992)
Mol. Pharmacol.
, vol.41
, pp. 1008-1015
-
-
Chambers, T.C.1
Zheng, B.2
Kuo, J.F.3
-
11
-
-
0028568630
-
The protein kinase C inhibitor, CGP 41 251, reverses decreased daunomycin uptake in a human drug-resistant ovarian carcinoma cell line
-
CHORVÁTH, B., SEDLÁK, J., NOVOTNÝ, L.: The protein kinase C inhibitor, CGP 41 251, reverses decreased daunomycin uptake in a human drug-resistant ovarian carcinoma cell line. Int. J. Cancer, 59, 1994, 852-853.
-
(1994)
Int. J. Cancer
, vol.59
, pp. 852-853
-
-
Chorváth, B.1
Sedlák, J.2
Novotný, L.3
-
12
-
-
0028588560
-
Inhibitors of protein kinase C
-
CORDGE, P.C., RYVES, W.J.: Inhibitors of protein kinase C. Cell. Signal., 6, 1994, 871-882.
-
(1994)
Cell. Signal.
, vol.6
, pp. 871-882
-
-
Cordge, P.C.1
Ryves, W.J.2
-
13
-
-
0028242089
-
Protein kinase C inhibitors induce apoptosis in human malignant glioma cell lines
-
COULDWELL, W.T., HINTON, D.R., HE, S., CHEN, T.C., SEBAT, I., WEISS, M.H., LAW, R.E.: Protein kinase C inhibitors induce apoptosis in human malignant glioma cell lines. FEBS Lett., 23, 1994, 43-46.
-
(1994)
FEBS Lett.
, vol.23
, pp. 43-46
-
-
Couldwell, W.T.1
Hinton, D.R.2
He, S.3
Chen, T.C.4
Sebat, I.5
Weiss, M.H.6
Law, R.E.7
-
14
-
-
0025871634
-
Transformed mammalian cells are deficient in kinase mediated control of progression through the G1 phase of their cell cycle
-
CRISSMAN, H.A., GADBOIS, D.B., TOBEY, R.A., BRADBURY, E.M.: Transformed mammalian cells are deficient in kinase mediated control of progression through the G1 phase of their cell cycle. Proc. Natl. Acad. Sci. USA, 88, 1991, 7580-7584.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 7580-7584
-
-
Crissman, H.A.1
Gadbois, D.B.2
Tobey, R.A.3
Bradbury, E.M.4
-
15
-
-
0029079228
-
Apoptosis in antitumor strategies: Modulation of cell cycle or differentiation
-
DARZYNKIEWICZ, Z.: Apoptosis in antitumor strategies: Modulation of cell cycle or differentiation. J. Cell. Biochem., 58, 1995, 151-159.
-
(1995)
J. Cell. Biochem.
, vol.58
, pp. 151-159
-
-
Darzynkiewicz, Z.1
-
16
-
-
0029068718
-
The protein kinase C inhibitor H7 blocks phosphorylation of stathmin during TPA-induced growth inhibition of human pre-B leukemia REH6 cells
-
DURAJ, J., KOVÁČIKOVÁ, M., SEDLÁK, J., KOPPEL, J., SOBEL, A., CHORVÁTH, B.: The protein kinase C inhibitor H7 blocks phosphorylation of stathmin during TPA-induced growth inhibition of human pre-B leukemia REH6 cells. Leukemia Res., 19, 1994, 457-461.
-
(1994)
Leukemia Res.
, vol.19
, pp. 457-461
-
-
Duraj, J.1
Kováčiková, M.2
Sedlák, J.3
Koppel, J.4
Sobel, A.5
Chorváth, B.6
-
17
-
-
0027267875
-
Reversal of doxorubicin-resistance in sarcoma 180 tumor cells by inhibition of different resistance mechanisms
-
EFFERTH, T., VOLM, M.: Reversal of doxorubicin-resistance in sarcoma 180 tumor cells by inhibition of different resistance mechanisms. Cancer Lett., 70, 1993, 197-202.
-
(1993)
Cancer Lett.
, vol.70
, pp. 197-202
-
-
Efferth, T.1
Volm, M.2
-
18
-
-
0027276494
-
The protein kinase inhibitor staurosporine induces morphological changes typical of apoptosis in MOLT-4 cells without concomitant DNA fragmentation
-
FALCIERI, E., MARTELLI, A.M., BAREGGI, R., CATALDI, A., COCCO, L.: The protein kinase inhibitor staurosporine induces morphological changes typical of apoptosis in MOLT-4 cells without concomitant DNA fragmentation. Biochem. Biophys. Res. Commun., 28, 1993, 19-25.
-
(1993)
Biochem. Biophys. Res. Commun.
, vol.28
, pp. 19-25
-
-
Falcieri, E.1
Martelli, A.M.2
Bareggi, R.3
Cataldi, A.4
Cocco, L.5
-
19
-
-
0028930725
-
Protein kinase A inhibitors enhance radiation-induced apoptosis
-
FINDIK, D., SONG, Q., HIDAKA, H., LAVIN, M.: Protein kinase A inhibitors enhance radiation-induced apoptosis. J. Cell Biochem., 57, 1995, 12-21.
-
(1995)
J. Cell Biochem.
, vol.57
, pp. 12-21
-
-
Findik, D.1
Song, Q.2
Hidaka, H.3
Lavin, M.4
-
20
-
-
0027427501
-
Differential effects of tyrosine kinase inhibition in CD69 antigen expression and lytic activity induced by rIL-2, rIL-12 and rIFN-α in human NK cells
-
GEROSA, F., TOMMASI, M., BENATI, C., GANDINI, G., LIBONATI, M., TRIDENTE, G., CARRA, G., TRINCHIERI, G.: Differential effects of tyrosine kinase inhibition in CD69 antigen expression and lytic activity induced by rIL-2, rIL-12 and rIFN-α in human NK cells. Cell Immunol., 150, 1993, 382-390.
-
(1993)
Cell Immunol.
, vol.150
, pp. 382-390
-
-
Gerosa, F.1
Tommasi, M.2
Benati, C.3
Gandini, G.4
Libonati, M.5
Tridente, G.6
Carra, G.7
Trinchieri, G.8
-
21
-
-
0028170263
-
Modulation of 1-[β-D-arabinofuranosyl] cytosine-induced apoptosis in human myeloid leukemia cells by staurosporine and other pharmacological inhibitors of protein kinase C
-
GRANT, S., TURNER, A.J., BARTIMOLE, T.M., NELMS, P.A., JOE, V.C., JARVIS, W.D.: Modulation of 1-[β-D-arabinofuranosyl] cytosine-induced apoptosis in human myeloid leukemia cells by staurosporine and other pharmacological inhibitors of protein kinase C. Oncol. Res., 6, 1994, 87-99.
-
(1994)
Oncol. Res.
, vol.6
, pp. 87-99
-
-
Grant, S.1
Turner, A.J.2
Bartimole, T.M.3
Nelms, P.A.4
Joe, V.C.5
Jarvis, W.D.6
-
22
-
-
0026481364
-
Potentiation of the activity of 1[β-D-arabinofuranosyl] cytosine by the protein kinase C activator bryostatin 1: Association with enhanced fragmentation of mature DNA
-
GRANT, S., JARVIS, W.D., SWERDLOW, P.S., TURNER, A.J., TRAYLOR, R.S., WALLACE, J.H., LIN, P.S., PETTIT, G. R., GEWIRTZ, D.A.: Potentiation of the activity of 1[β-D-arabinofuranosyl] cytosine by the protein kinase C activator bryostatin 1: Association with enhanced fragmentation of mature DNA. Cancer Res., 52, 1992, 6270-6278.
-
(1992)
Cancer Res.
, vol.52
, pp. 6270-6278
-
-
Grant, S.1
Jarvis, W.D.2
Swerdlow, P.S.3
Turner, A.J.4
Traylor, R.S.5
Wallace, J.H.6
Lin, P.S.7
Pettit, G.R.8
Gewirtz, D.A.9
-
23
-
-
0027957568
-
Effect of calphostin C (PKC inhibitor) on daunorubicin resistance in P388/AR cells and HL60/AR cells: Reversal of drug resistance possibly via P-glycoprotein
-
GUPTA, S., PATEL, K., SINGH, H., GOLAPUDI, S.: Effect of calphostin C (PKC inhibitor) on daunorubicin resistance in P388/AR cells and HL60/AR cells: Reversal of drug resistance possibly via P-glycoprotein. Cancer Lett., 76, 1994, 139-145.
-
(1994)
Cancer Lett.
, vol.76
, pp. 139-145
-
-
Gupta, S.1
Patel, K.2
Singh, H.3
Golapudi, S.4
-
24
-
-
0028302712
-
Protein kinase C mediates basic fibroblast growth factor protection of endothelial cells against radiation-induced apoptosis
-
HAIMOWITZ-FRIEDMAN, A., BALABAN, N., MCLOUGHLIN, M., EHLEITER, D., MICHAELI, J., VLODAVSKY, I., FUKS, Z.: Protein kinase C mediates basic fibroblast growth factor protection of endothelial cells against radiation-induced apoptosis. Cancer Res., 54, 1994, 2591-2597.
-
(1994)
Cancer Res.
, vol.54
, pp. 2591-2597
-
-
Haimowitz-Friedman, A.1
Balaban, N.2
Mcloughlin, M.3
Ehleiter, D.4
Michaeli, J.5
Vlodavsky, I.6
Fuks, Z.7
-
25
-
-
0027738598
-
The selective protein kinase inhibitor GF 109203X inhibits phorbol ester-induced morphological and functional differentiation of SH-SY5Y human neuroblastoma cells
-
HEIKKILA, J., JALAVA, A., ERIKSSON, K.: The selective protein kinase inhibitor GF 109203X inhibits phorbol ester-induced morphological and functional differentiation of SH-SY5Y human neuroblastoma cells. Biochem. Biophys. Res. Commun., 197, 1993, 1185-1193.
-
(1993)
Biochem. Biophys. Res. Commun.
, vol.197
, pp. 1185-1193
-
-
Heikkila, J.1
Jalava, A.2
Eriksson, K.3
-
26
-
-
0027931144
-
Mechanism of interferon action, translational control and the RNA-dependent protein kinase (PKR): Antagonists of PKR enhance the translational activity of mRNAs that include a 161 nucleotide region from reovirus s1 mRNA
-
HENRY, G.L., MCCORMACK, S.J., THOMIS, D.C., SAMUEL, C. J.: Mechanism of interferon action, translational control and the RNA-dependent protein kinase (PKR): antagonists of PKR enhance the translational activity of mRNAs that include a 161 nucleotide region from reovirus s1 mRNA. J. Biol. Regul. Homeost Agents, 8, 1994, 15-24.
-
(1994)
J. Biol. Regul. Homeost Agents
, vol.8
, pp. 15-24
-
-
Henry, G.L.1
Mccormack, S.J.2
Thomis, D.C.3
Samuel, C.J.4
-
27
-
-
0024599749
-
Induction of erythroid differentiation of K-562 human leukemic cells by herbimycin A, an inhibitor of tyrosine kinase activity
-
HONMA, Y., OKABE-KADO, J., HOZUMI, M., UEHARA, M., MIZUNO, S.: Induction of erythroid differentiation of K-562 human leukemic cells by herbimycin A, an inhibitor of tyrosine kinase activity. Cancer Res., 49, 1989, 331-334.
-
(1989)
Cancer Res.
, vol.49
, pp. 331-334
-
-
Honma, Y.1
Okabe-Kado, J.2
Hozumi, M.3
Uehara, M.4
Mizuno, S.5
-
28
-
-
0026587326
-
Effects of herbimycin a derivatives on growth and differentiation of K-562 human leukemic cells
-
HONMA, Y., KASUKABE, T., HOZUMI, M., SHIBATA, K., OMURA, S.: Effects of herbimycin A derivatives on growth and differentiation of K-562 human leukemic cells. Anti-Cancer Res., 12, 1992, 189-192.
-
(1992)
Anti-Cancer Res.
, vol.12
, pp. 189-192
-
-
Honma, Y.1
Kasukabe, T.2
Hozumi, M.3
Shibata, K.4
Omura, S.5
-
29
-
-
0026525565
-
Induction of differentiation of human leukemia cells with structurally altered c-abl (bcr-abl) gene by herbimycin A, an inhibitor of tyrosine kinase activity
-
HONMA, Y., KASUKABE, T., HOZUMI, M., MAEKI, N., SAKURAI, M., SAKASHITA, S., TSURUOKA, N.: Induction of differentiation of human leukemia cells with structurally altered c-abl (bcr-abl) gene by herbimycin A, an inhibitor of tyrosine kinase activity. Leukemia, 6, 1992, 229-231.
-
(1992)
Leukemia
, vol.6
, pp. 229-231
-
-
Honma, Y.1
Kasukabe, T.2
Hozumi, M.3
Maeki, N.4
Sakurai, M.5
Sakashita, S.6
Tsuruoka, N.7
-
30
-
-
0027252599
-
Phorbol ester-induced modulation of cell surface antigens on U-937 cells in protein-free medium: Effects of protein kinase and calmodulin inhibitors
-
HUNAKOVÁ, L., SEDLAK, J., CHORVÁTH, B.: Phorbol ester-induced modulation of cell surface antigens on U-937 cells in protein-free medium: Effects of protein kinase and calmodulin inhibitors. Neoplasma, 40, 1993, 141-146.
-
(1993)
Neoplasma
, vol.40
, pp. 141-146
-
-
Hunaková, L.1
Sedlak, J.2
Chorváth, B.3
-
31
-
-
0028282865
-
Tyrosine kinase inhibitor-induced differentiation of K-562 cells: Alterations of cell cycle and cell surface phenotype
-
HUNÁKOVÁ, L., SEDLÁK, J., KLOBUŠICKÁ, M., DURAJ, J., CHORVÁTH, B.: Tyrosine kinase inhibitor-induced differentiation of K-562 cells: Alterations of cell cycle and cell surface phenotype. Cancer Lett., 81, 1994, 81-87.
-
(1994)
Cancer Lett.
, vol.81
, pp. 81-87
-
-
Hunáková, L.1
Sedlák, J.2
Klobušická, M.3
Duraj, J.4
Chorváth, B.5
-
32
-
-
0028790294
-
Phorbol ester (TPA)-mduced differential modulation of cell surface antigens in hemopoietic pluripotential leukemia (K-562) cell line: Effects of protein kinase inhibitors with broad- and PKC selective inhibitory activity
-
HUNÁKOVÁ, L., SEDLAK, J., KLOBUŠICKÁ, M., CHORVÁTH, B.: Phorbol ester (TPA)-mduced differential modulation of cell surface antigens in hemopoietic pluripotential leukemia (K-562) cell line: Effects of protein kinase inhibitors with broad- and PKC selective inhibitory activity. Neoplasma, 42, 1995, 249-253.
-
(1995)
Neoplasma
, vol.42
, pp. 249-253
-
-
Hunáková, L.1
Sedlak, J.2
Klobušická, M.3
Chorváth, B.4
-
33
-
-
0027969199
-
Epidermal growth factor induces PC12 cell differentiation in the presence of the protein kinase inhibitor K-252A
-
ISONO, F., WIDMER, H.R., HEFTI, F., KNUSEL, B.: Epidermal growth factor induces PC12 cell differentiation in the presence of the protein kinase inhibitor K-252A. J. Neurochem., 63, 1994, 1235-1245.
-
(1994)
J. Neurochem.
, vol.63
, pp. 1235-1245
-
-
Isono, F.1
Widmer, H.R.2
Hefti, F.3
Knusel, B.4
-
34
-
-
0027193145
-
Protein kinase inhibitor, staurosporine, induces a mature neuronal phenotype in SH-SYS5 human neuroblastoma cells trough alpha-, beta- and zeta- protein kinase C-independent pathway
-
JALAVA, A., AKERMAN, K., HEIKKILA, J.: Protein kinase inhibitor, staurosporine, induces a mature neuronal phenotype in SH-SYS5 human neuroblastoma cells trough alpha-, beta- and zeta- protein kinase C-independent pathway. J. Cell Physiol., 155, 1993, 301-312.
-
(1993)
J. Cell Physiol.
, vol.155
, pp. 301-312
-
-
Jalava, A.1
Akerman, K.2
Heikkila, J.3
-
35
-
-
0028316195
-
Induction of apoptotic DNA fragmentation and cell death in HL-60 human promyelocytic leukemia cells by pharmacological inhibitors of protein kinase C
-
JARVIS, W.D., TURNER, A.J., POVIRK, L.F., TRAYLOR, R.S., GRANT, S.: Induction of apoptotic DNA fragmentation and cell death in HL-60 human promyelocytic leukemia cells by pharmacological inhibitors of protein kinase C. Cancer Res., 54, 1994, 1707-1714.
-
(1994)
Cancer Res.
, vol.54
, pp. 1707-1714
-
-
Jarvis, W.D.1
Turner, A.J.2
Povirk, L.F.3
Traylor, R.S.4
Grant, S.5
-
36
-
-
0028017571
-
Activation of ras and formation of GAP complex during TPA-induced monocytic differentiation of HL-60 cells
-
KATAGIRI, K., HATTORI, S., NAKAMURA, S., YAMAMOTO, S., YOSHIDA, T., KATAGIRI, T.: Activation of ras and formation of GAP complex during TPA-induced monocytic differentiation of HL-60 cells. Blood, 84, 1994, 1780-1789.
-
(1994)
Blood
, vol.84
, pp. 1780-1789
-
-
Katagiri, K.1
Hattori, S.2
Nakamura, S.3
Yamamoto, S.4
Yoshida, T.5
Katagiri, T.6
-
37
-
-
0027746249
-
Inhibition of Abelson oncogene function by erbstatin analogues
-
KAWADA, M., TAWARA, J., TSUJI, T., HONMA, Y., HOZUMI, M., WANG, J.Y., UMEZAWA, K.: Inhibition of Abelson oncogene function by erbstatin analogues. Drugs Exp. Clin. Res., 19, 1993, 235-241.
-
(1993)
Drugs Exp. Clin. Res.
, vol.19
, pp. 235-241
-
-
Kawada, M.1
Tawara, J.2
Tsuji, T.3
Honma, Y.4
Hozumi, M.5
Wang, J.Y.6
Umezawa, K.7
-
38
-
-
0022842651
-
The role of protein kinase C in transmembrane signalling
-
KIKKAWA, U., NISHIZUKA, Y.: The role of protein kinase C in transmembrane signalling. Ann. Rev. Cell Biol., 2, 1986, 149-168.
-
(1986)
Ann. Rev. Cell Biol.
, vol.2
, pp. 149-168
-
-
Kikkawa, U.1
Nishizuka, Y.2
-
39
-
-
0028332026
-
Double-stranded RNA-dependent protein kinase activates transcription factor NF-B by phosphorylating I-B
-
KUMAR, A., HAQUE, J., LACOSTE, J., HISCOTT, J., WILLIAMS, B.R.: Double-stranded RNA-dependent protein kinase activates transcription factor NF-B by phosphorylating I-B. Proc. Natl. Acad. Sci: USA, 91, 1994, 6288-6292.
-
(1994)
Proc. Natl. Acad. Sci: USA
, vol.91
, pp. 6288-6292
-
-
Kumar, A.1
Haque, J.2
Lacoste, J.3
Hiscott, J.4
Williams, B.R.5
-
40
-
-
0028285894
-
Effect of protein kinase C inhibitor staurosporine on chemosensitivity to daunorubicin of normal and leukemic fresh myeloid cells
-
LAREDO, J., HUYNH, A., MULLER, C., JAFFREZOU, J.P., BAILLY, J.D., CASSAR, G., LAURENT, G., DEMUR, C.: Effect of protein kinase C inhibitor staurosporine on chemosensitivity to daunorubicin of normal and leukemic fresh myeloid cells. Blood, 84, 1994, 229-237.
-
(1994)
Blood
, vol.84
, pp. 229-237
-
-
Laredo, J.1
Huynh, A.2
Muller, C.3
Jaffrezou, J.P.4
Bailly, J.D.5
Cassar, G.6
Laurent, G.7
Demur, C.8
-
41
-
-
0028290902
-
The interferon-induced double-stranded RNA-activated protein kinase induces apoptosis
-
LEE, S.B., ESTEBAN, M.: The interferon-induced double-stranded RNA-activated protein kinase induces apoptosis. Virology, 199, 1994, 491-496.
-
(1994)
Virology
, vol.199
, pp. 491-496
-
-
Lee, S.B.1
Esteban, M.2
-
42
-
-
3643066352
-
The role of P-glycoprotein in drug resistance
-
Eds: Fortner, J.G., Rhoads, J.E. Philadelphia, J.B. Lippincott
-
LING, V.: The role of P-glycoprotein in drug resistance. In: Accomplishments in Cancer Research. Eds: Fortner, J.G., Rhoads, J.E. Philadelphia, J.B. Lippincott 1990.
-
(1990)
Accomplishments in Cancer Research
-
-
Ling, V.1
-
43
-
-
0027968951
-
Evidence for involvement of tyrosine phosphorylation in taxol-induced apoptosis in a human ovarian tumor cell lines
-
LIU, Y., BHALLA, K., HILL, C., PRIEST, D.G.: Evidence for involvement of tyrosine phosphorylation in taxol-induced apoptosis in a human ovarian tumor cell lines. Biochem. Pharmacol., 15, 1994, 1265-1272.
-
(1994)
Biochem. Pharmacol.
, vol.15
, pp. 1265-1272
-
-
Liu, Y.1
Bhalla, K.2
Hill, C.3
Priest, D.G.4
-
44
-
-
0024215837
-
The role of protein phosphorylation in the control of cell growth and differentiation
-
LORD, J.M., BUNCE, C.M., BROWN, G.: The role of protein phosphorylation in the control of cell growth and differentiation. Br. J. Cancer, 58, 1988, 549-553.
-
(1988)
Br. J. Cancer
, vol.58
, pp. 549-553
-
-
Lord, J.M.1
Bunce, C.M.2
Brown, G.3
-
45
-
-
0028326740
-
Protein kinase C activation promotes cell survival in mature lymphocytes prone to apoptosis
-
LUCAS, M., SANCHEZ-MARGALET, V., SANZ, A., SOLANO, F.: Protein kinase C activation promotes cell survival in mature lymphocytes prone to apoptosis. Biochem. Pharmacol., 47, 1994, 667-672.
-
(1994)
Biochem. Pharmacol.
, vol.47
, pp. 667-672
-
-
Lucas, M.1
Sanchez-Margalet, V.2
Sanz, A.3
Solano, F.4
-
46
-
-
3643104906
-
Cell cycle inhibitory protein kinases
-
Eds: Fortner, J.G., Rhoads, J.E. Philadelphia, J.B. Lippincott
-
LUNDGREN, K., BEACH, D.: Cell cycle inhibitory protein kinases. In: Accomplishments in Cancer Research 1990. Eds: Fortner, J.G., Rhoads, J.E. Philadelphia, J.B. Lippincott 1990, 162-173.
-
(1990)
Accomplishments in Cancer Research 1990
, pp. 162-173
-
-
Lundgren, K.1
Beach, D.2
-
47
-
-
0027076780
-
Regulation by phorbol ester and protein kinase C inhibitors and by protein phosphatase inhibitor (okadaic acid) of P-glycoprotein phosphorylation and relationship to drug accumulation in multidrug-resistant human KB cells
-
MA, L., MARQUARDT, L., TAKEMOTO, L., CENTER, M.S.: Regulation by phorbol ester and protein kinase C inhibitors and by protein phosphatase inhibitor (okadaic acid) of P-glycoprotein phosphorylation and relationship to drug accumulation in multidrug-resistant human KB cells. Mol. Pharmacol., 41, 1992, 1008-1015.
-
(1992)
Mol. Pharmacol.
, vol.41
, pp. 1008-1015
-
-
Ma, L.1
Marquardt, L.2
Takemoto, L.3
Center, M.S.4
-
48
-
-
0027893202
-
Differentiation of human myeloblastic leukemia ML-1 cells into macrophages by staurosporine, an inhibitor of protein kinase activities
-
MAKASHIMA, M., HONMA, Y., HOZUMI, M., SAMPI, K., MOTOYOSHI, K., NAGATA, N., HATTORI, M.: Differentiation of human myeloblastic leukemia ML-1 cells into macrophages by staurosporine, an inhibitor of protein kinase activities. Exp. Hematol., 21, 1993, 839-845.
-
(1993)
Exp. Hematol.
, vol.21
, pp. 839-845
-
-
Makashima, M.1
Honma, Y.2
Hozumi, M.3
Sampi, K.4
Motoyoshi, K.5
Nagata, N.6
Hattori, M.7
-
49
-
-
0028111312
-
Inhibition of DNA topoisomerases I and II and induction of apoptosis by erbstatin and tyrphostin derivatives
-
MARKOVITS, J., LARSEN, A.K., SEGAL-BENDIRDJIAN, E., FOSSE, P., SAUCIER, J.M., GAZIT, A., LEVITZKI, A., UMEZAWA, K., JACQUEMIN-SABLON, A.: Inhibition of DNA topoisomerases I and II and induction of apoptosis by erbstatin and tyrphostin derivatives. Biochem. Pharmacol., 48, 1994, 549-560.
-
(1994)
Biochem. Pharmacol.
, vol.48
, pp. 549-560
-
-
Markovits, J.1
Larsen, A.K.2
Segal-Bendirdjian, E.3
Fosse, P.4
Saucier, J.M.5
Gazit, A.6
Levitzki, A.7
Umezawa, K.8
Jacquemin-Sablon, A.9
-
50
-
-
0028089807
-
Interleukin-3 and bryostatin-1 mediate hyperphosphorylation of bcl-2 alpha in association with suppression of apoptosis
-
MAY, W.S., TYLER, P.G., ITO, T., ARMSTRONG, D.K., QATSHA, K.A., DAVIDSON, N.E.: Interleukin-3 and bryostatin-1 mediate hyperphosphorylation of bcl-2 alpha in association with suppression of apoptosis. J. Biol. Chem., 269, 1994, 26 865-26 870.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 26865-26870
-
-
May, W.S.1
Tyler, P.G.2
Ito, T.3
Armstrong, D.K.4
Qatsha, K.A.5
Davidson, N.E.6
-
51
-
-
0024402595
-
Inhibition of DNA fragmentation in thymocytes and isolated thymocyte nuclei by agents that stimulate protein kinase
-
MCCONKEY, D.J., HARTZELL, P., JONDAL, M., ARRENIUS, S.: Inhibition of DNA fragmentation in thymocytes and isolated thymocyte nuclei by agents that stimulate protein kinase. C. J. Biol. Chem., 264, 1989, 13 399-13 402.
-
(1989)
C. J. Biol. Chem.
, vol.264
, pp. 13399-13402
-
-
Mcconkey, D.J.1
Hartzell, P.2
Jondal, M.3
Arrenius, S.4
-
52
-
-
0024379951
-
A derivative of staurosporine (CGP 41 251) shows selectivity for protein kinase C inhibition and in vitro anti-proliferative as well as in vivo anti-tumor activity
-
MEYER, T., REGENASS, U., FABBRO, D., ALTERI, E., ROSSEL, J., MULLER, M., CARAVATTI, G., MATTER, A.: A derivative of staurosporine (CGP 41 251) shows selectivity for protein kinase C inhibition and in vitro anti-proliferative as well as in vivo anti-tumor activity. Int. J. Cancer, 43, 1989, 851-856.
-
(1989)
Int. J. Cancer
, vol.43
, pp. 851-856
-
-
Meyer, T.1
Regenass, U.2
Fabbro, D.3
Alteri, E.4
Rossel, J.5
Muller, M.6
Caravatti, G.7
Matter, A.8
-
53
-
-
3643133996
-
Studies and prospectives of the protein kinase C family for cellular regulation
-
Eds: Fortner, J.G., Rhoads, J.E. Philadelphia, J.B. Lippincott
-
NISHIZUKA, Y.: Studies and prospectives of the protein kinase C family for cellular regulation. In: Accomplishments in Cancer Research. Eds: Fortner, J.G., Rhoads, J.E. Philadelphia, J.B. Lippincott, 1988, 100-120.
-
(1988)
Accomplishments in Cancer Research
, pp. 100-120
-
-
Nishizuka, Y.1
-
54
-
-
0028150702
-
Growth-inhibitory effects of the natural phytoestrogen genistein in MCF-7 human breast cancer cells
-
PAGLIACCI, M.C., SMACCHIA, M., MIGLIORATI, G., GRIGNANI, F., RICCARDI, C., NICOLETTI, I.: Growth-inhibitory effects of the natural phytoestrogen genistein in MCF-7 human breast cancer cells. Eur. J. Cancer, 30A, 1994, 1675-1682.
-
(1994)
Eur. J. Cancer
, vol.30 A
, pp. 1675-1682
-
-
Pagliacci, M.C.1
Smacchia, M.2
Migliorati, G.3
Grignani, F.4
Riccardi, C.5
Nicoletti, I.6
-
55
-
-
0029046001
-
Changes in protein kinase C isoenzyme expression associated with apoptosis in U937 myelomonocytic cells
-
PONGRACZ, J., TUFFLEY, W., JOHNSON, G.D., DEACON, E.M., BURNETT, D., STOCKLEY, R.A., LORD, J.M.: Changes in protein kinase C isoenzyme expression associated with apoptosis in U937 myelomonocytic cells. Exptl. Cell Res., 218, 1995, 430-438.
-
(1995)
Exptl. Cell Res.
, vol.218
, pp. 430-438
-
-
Pongracz, J.1
Tuffley, W.2
Johnson, G.D.3
Deacon, E.M.4
Burnett, D.5
Stockley, R.A.6
Lord, J.M.7
-
56
-
-
0029022737
-
Human interleukin-3 receptor modulated bcl-2 mRNA and protein levels through protein kinase C in TF-1 cells
-
RINAUDO, M.S., SU, K., FALK, L.A., HALDER, S., MUFSON, A.D.: Human interleukin-3 receptor modulated bcl-2 mRNA and protein levels through protein kinase C in TF-1 cells. Blood, 86, 1995, 80-88.
-
(1995)
Blood
, vol.86
, pp. 80-88
-
-
Rinaudo, M.S.1
Su, K.2
Falk, L.A.3
Halder, S.4
Mufson, A.D.5
-
57
-
-
0028959525
-
Effects of protein kinase C inhibitor, staurosporine derivative CGP 41 251, on cell cycle, DNA synthesis and drug uptake in neoplastic cell lines
-
SEDLÁK, J., HUNÁKOVÁ, L., DURAJ, J., CHORVÁTH, B., NOVOTNÝ, L.: Effects of protein kinase C inhibitor, staurosporine derivative CGP 41 251, on cell cycle, DNA synthesis and drug uptake in neoplastic cell lines. Anti-Cancer Drugs, 6, 1995, 70-76.
-
(1995)
Anti-Cancer Drugs
, vol.6
, pp. 70-76
-
-
Sedlák, J.1
Hunáková, L.2
Duraj, J.3
Chorváth, B.4
Novotný, L.5
-
58
-
-
0029166239
-
Differential effects of protein kinase inhibitors (staurosporine and CGP 41 251) on TPA-induced homotypic aggregation and cell surface adhesion antigen expression in human monoblastoid cell line U-937
-
SEDLÁK, J., ŠULIKOVÁ, M., HUNÁKOVÁ, L., CHORVÁTH, B.: Differential effects of protein kinase inhibitors (staurosporine and CGP 41 251) on TPA-induced homotypic aggregation and cell surface adhesion antigen expression in human monoblastoid cell line U-937. Neoplasma, 42, 1995, 159-165.
-
(1995)
Neoplasma
, vol.42
, pp. 159-165
-
-
Sedlák, J.1
Šuliková, M.2
Hunáková, L.3
Chorváth, B.4
-
59
-
-
0029058436
-
Cisplatin resistance in a murine leukemia cell line is associated with a defective apoptotic process
-
SEGAL-BENDIRDJIAN, E., JACQUEMIN-SABLON, A.: Cisplatin resistance in a murine leukemia cell line is associated with a defective apoptotic process. Exp. Cell Res., 218, 1995, 201-212.
-
(1995)
Exp. Cell Res.
, vol.218
, pp. 201-212
-
-
Segal-Bendirdjian, E.1
Jacquemin-Sablon, A.2
-
60
-
-
0028068084
-
Involvement of protein kinase C and protein tyrosine kinase in lipopolysaccharide-induced TNF-α and IL-1β production by human monocytes
-
SHAPIRA, L., TAKASHIBA, S., CHAMPAGNE, C., AMAR, S., VAN DYKE, T.E.: Involvement of protein kinase C and protein tyrosine kinase in lipopolysaccharide-induced TNF-α and IL-1β production by human monocytes. J. Immunol., 153, 1994, 1818-1824.
-
(1994)
J. Immunol.
, vol.153
, pp. 1818-1824
-
-
Shapira, L.1
Takashiba, S.2
Champagne, C.3
Amar, S.4
Van Dyke, T.E.5
-
61
-
-
0028244459
-
The natural tyrosine kinase inhibitor, genistein produces cell cycle arrest and apoptosis in Jurkat T-leukemia cells
-
SPINOZZI, F., PAGLIACCI, M.C., MIGLIORATI, G., MORACA, R., GRIGNANI, F., RICCARDI, C., NICOLETTI, I.: The natural tyrosine kinase inhibitor, genistein produces cell cycle arrest and apoptosis in Jurkat T-leukemia cells. Leuk. Res., 18, 1994, 431-439.
-
(1994)
Leuk. Res.
, vol.18
, pp. 431-439
-
-
Spinozzi, F.1
Pagliacci, M.C.2
Migliorati, G.3
Moraca, R.4
Grignani, F.5
Riccardi, C.6
Nicoletti, I.7
-
62
-
-
0028328492
-
Effect of staurosporine on MOLT-4 cell progression through G2 and on cytokinesis
-
TRAGANOS, F., GONG, J., ARDELT, B., DARZYNKIEWICZ, Z.: Effect of staurosporine on MOLT-4 cell progression through G2 and on cytokinesis. J. Cell Physiol., 158, 1994, 535-544.
-
(1994)
J. Cell Physiol.
, vol.158
, pp. 535-544
-
-
Traganos, F.1
Gong, J.2
Ardelt, B.3
Darzynkiewicz, Z.4
-
63
-
-
0026781538
-
Ionizing radiation stimulates unidentified tyrosine-specific protein kinases in human B-lymphocyte precursors, triggering apoptosis and clonogenic cell death
-
UCKUN, F.M., TUEL-AHLGREN, L., SONG, C.W., WADDICK, K., MYERS, D.E., KIRIHARA, J., LEDBETTER, J.A., SCHIEVEN, G.L.: Ionizing radiation stimulates unidentified tyrosine-specific protein kinases in human B-lymphocyte precursors, triggering apoptosis and clonogenic cell death. Proc. Natl. Acad Sci. USA, 89, 1992, 9005-9009.
-
(1992)
Proc. Natl. Acad Sci. USA
, vol.89
, pp. 9005-9009
-
-
Uckun, F.M.1
Tuel-Ahlgren, L.2
Song, C.W.3
Waddick, K.4
Myers, D.E.5
Kirihara, J.6
Ledbetter, J.A.7
Schieven, G.L.8
-
64
-
-
0028985934
-
Biotherapy of B-cell precursor leukemia by targeting genistein to CD19-associated tyrosine kinases
-
UCKUN, F.M., EVANS, W.E., FORSYTH, C.J., WADDICK, K.G., AHLGREN, L.T., CHELSTROM, L.M., BURKHARDT, A., BOLEN, J., MEYERS, D.E.: Biotherapy of B-cell precursor leukemia by targeting genistein to CD19-associated tyrosine kinases. Science, 267, 1995, 886-891.
-
(1995)
Science
, vol.267
, pp. 886-891
-
-
Uckun, F.M.1
Evans, W.E.2
Forsyth, C.J.3
Waddick, K.G.4
Ahlgren, L.T.5
Chelstrom, L.M.6
Burkhardt, A.7
Bolen, J.8
Meyers, D.E.9
-
65
-
-
0028231242
-
The protein kinase C inhibitor CGP 41 251, a staurosporine derivative with antitumor activity reverses multidrug resistance
-
UTZ, I., HOFER, S., REGENASS, U., HILBE, W., THALER, J., GRUNICKE, H., HOFMANN, J.: The protein kinase C inhibitor CGP 41 251, a staurosporine derivative with antitumor activity reverses multidrug resistance. Int. J. Cancer, 57, 1994, 104-110.
-
(1994)
Int. J. Cancer
, vol.57
, pp. 104-110
-
-
Utz, I.1
Hofer, S.2
Regenass, U.3
Hilbe, W.4
Thaler, J.5
Grunicke, H.6
Hofmann, J.7
-
66
-
-
0027716505
-
Transient exposure of human eosinophils to the protein kinase C inhibitors CGP39-360, CGP41-251 and CGP44-800 leads to priming of the respiratory burst induced by opsonized particles
-
VAN DER BRUGGEN, T., KOK, P.T.M., BLOM, M., VERHOEEVEN, A.J., RAAIJMAKERS, J.A.M., LAMMERS, J.W.J., KOENDERMAN, L.: Transient exposure of human eosinophils to the protein kinase C inhibitors CGP39-360, CGP41-251 and CGP44-800 leads to priming of the respiratory burst induced by opsonized particles. J. Leukocyte Biol., 54, 1993, 552-557.
-
(1993)
J. Leukocyte Biol.
, vol.54
, pp. 552-557
-
-
Van Der Bruggen, T.1
Kok, P.T.M.2
Blom, M.3
Verhoeeven, A.J.4
Raaijmakers, J.A.M.5
Lammers, J.W.J.6
Koenderman, L.7
-
67
-
-
0027482403
-
Genistein modulates the decreased drug accumulation in non-P glycoprotein mediated multidrug resistant tumor cells
-
VERSANTVOORT, C.H.M., SCHUURHUIS, G.J., PINEDO, H.M., EEKMAN, C.A., KUIPER, C.M., LANKELMA, J., BROXTERMAN, H.J.: Genistein modulates the decreased drug accumulation in non-P glycoprotein mediated multidrug resistant tumor cells. Br. J. Cancer, 68, 1993, 939-946.
-
(1993)
Br. J. Cancer
, vol.68
, pp. 939-946
-
-
Versantvoort, C.H.M.1
Schuurhuis, G.J.2
Pinedo, H.M.3
Eekman, C.A.4
Kuiper, C.M.5
Lankelma, J.6
Broxterman, H.J.7
-
68
-
-
0026035529
-
Induction of in vitro differentiation of mouse erythroleukemia cells by genistein, an inhibitor of protein tyrosine kinase
-
WATANABE, T., KONDO, K., OISHI, M.: Induction of in vitro differentiation of mouse erythroleukemia cells by genistein, an inhibitor of protein tyrosine kinase. Cancer Res., 51, 1991, 764-768.
-
(1991)
Cancer Res.
, vol.51
, pp. 764-768
-
-
Watanabe, T.1
Kondo, K.2
Oishi, M.3
-
69
-
-
0027931213
-
Enhanced cell differentiation when Rb is hypophosphorylated and down-regulated by radicicol, a src-kinase inhibitor
-
YEN, A., SOONG, S., KWON, H.J., YOSHIDA, M., BEPPU, T., VARVAYANNIS, S.: Enhanced cell differentiation when Rb is hypophosphorylated and down-regulated by radicicol, a src-kinase inhibitor. Exp. Cell Res., 214, 1994, 163-171.
-
(1994)
Exp. Cell Res.
, vol.214
, pp. 163-171
-
-
Yen, A.1
Soong, S.2
Kwon, H.J.3
Yoshida, M.4
Beppu, T.5
Varvayannis, S.6
-
70
-
-
0028290459
-
Human leukemia K-562 cell mutant (K-562/OA200) selected for resistance to okadaic acid (protein phosphatase inhibitor) lacks protein kinase C epsilon, exhibits multidrug phenotype and expresses drug pump P-glycoprotein
-
ZHENG, B., CHAMBERS, T.C., RAYNOR, R.L., MARKHAM, P.N., GEBEL, H.M., VOGLER, W.R., KUO, J.F.: Human leukemia K-562 cell mutant (K-562/OA200) selected for resistance to okadaic acid (protein phosphatase inhibitor) lacks protein kinase C epsilon, exhibits multidrug phenotype and expresses drug pump P-glycoprotein. J. Biol. Chem., 269, 1994, 12 332-12 338.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 12332-12338
-
-
Zheng, B.1
Chambers, T.C.2
Raynor, R.L.3
Markham, P.N.4
Gebel, H.M.5
Vogler, W.R.6
Kuo, J.F.7
-
71
-
-
0027074965
-
Effects of staurosporine, K-252a and other structurally related protein kinase inhibitors on shape and locomotion of Walker carcinosarcoma cells
-
ZIMMERMANN, A., KELLER, H.: Effects of staurosporine, K-252a and other structurally related protein kinase inhibitors on shape and locomotion of Walker carcinosarcoma cells. Br. J. Cancer, 66, 1992, 1077-1082.
-
(1992)
Br. J. Cancer
, vol.66
, pp. 1077-1082
-
-
Zimmermann, A.1
Keller, H.2
|