Protein engineering of a novel constitutively active hormone-receptor complex

Journal of Biological Chemistry

Volumn 271, Issue 49, 1996, Pages 31638-31642

  Wu, Chengbin ^a   Narayan, Prema ^a   Puett, David ^a  

^a UNIVERSITY OF GEORGIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHORIONIC GONADOTROPIN; CHORIONIC GONADOTROPIN ALPHA SUBUNIT; CHORIONIC GONADOTROPIN BETA SUBUNIT; CHORIONIC GONADOTROPIN RECEPTOR; CYCLIC AMP; GUANINE NUCLEOTIDE BINDING PROTEIN;

ANIMAL CELL; ARTICLE; CELL STRAIN COS1; CONTROLLED STUDY; COVALENT BOND; DNA TRANSFECTION; EMBRYO; GENETIC ENGINEERING; HORMONE RECEPTOR INTERACTION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; CELL LINE; CHORIONIC GONADOTROPIN; COS CELLS; CYCLIC AMP; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; PROTEIN CONFORMATION; PROTEIN ENGINEERING; RECEPTORS, GONADOTROPIN; RECEPTORS, LH; RECOMBINANT FUSION PROTEINS; RESTRICTION MAPPING; TRANSFECTION;

ANIMALIA;

EID: 0029856730     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.49.31638     Document Type: Article

References (28)

1. Pierce, J. G., and Parsons, T. F. (1981) Annu. Rev. Biochem. 50, 465-495
2. Ryan, R. J., Charlesworth, M. C., McCormick, D. J., Milius, R. P., and Keutmann, H. T. (1988) FASEB J. 2, 2661-2669
3. El-Deiry, S., Kaetzel, D., Kennedy, G., Nilson, J., and Puett, D. (1989) Mol. Endocrinol. 3, 1523-1528
4. Matzuk, M. M., Hsueh, A. J. W., Lapolt, P., Tsafriri, A., Keene, J. L., and Boime, I. (1990) Endocrinology 126, 376-383
5. McFarland, K. C., Sprengel, R., Phillips, H. S., Kohler, M., Rosemblit, N., Nikolics, K., Segaloff, D. L., and Seeburg, P. J. (1989) Science 245, 494-499
6. Segaloff, D. L., and Ascoli, M. (1993) Endocrine Rev. 14, 324-347
7. Tsai-Morris, C. H., Buczko, E., Wang, W., and Dufau, M. L. (1990) J. Biol. Chem. 265, 19385-19388
8. Xie, Y.-B., Wang, H., and Segaloff, D. L. (1990) J. Biol. Chem. 265, 21411-21414
9. Braun, T., Schofield, P. R., and Sprengel, R. (1991) EMBO J. 10, 1885-1890
10. Ji, I., and Ji, T. H. (1991) Endocrinology 128, 2648-2650
11. Moyle, W. R., Bernard, M. P., Myers, R. V., Marko, O. M., and Strader, C. D. (1991) J. Biol. Chem. 266, 10807-10812
12. Lapthorn, A. J., Harris, D. C., Littlejohn, A., Lustbader, J. W., Canfleld, R. E., Machin, K. J., Morgan, F. J., and Isaacs, N. W. (1994) Nature 369, 455-461
13. Wu, H., Lustbader, J. W., Liu, Y., Canfield, R. E., and Hendrickson, W. A. (1994) Structure 2, 545-558
14. Moyle, W. R., Campbell, R. K., Rao, S. N. V., Ayad, N. G., Bernard, M. F., Han, Y., and Wang, Y. (1995) J. Biol. Chem. 270, 20020-20032
15. Jiang, X., Dreano, M., Buckler, D. R., Cheng, S., Ythier, A., Wu, H., Hendrickson, W. A., and Tayar, N. E. (1995) Structure 3, 1341-1353
16. Couture, L., Naharisoa, H., Grebert, D., Remy, J.-J., Pajot-Augy, E., Bozon, V., Haertle, T., and Salesse, R. (1996) J. Mol. Endocrinol. 16, 15-25
17. Bhowmick, N., Huang, J., Puett, D., Isaacs, N. W., and Lapthorn, A. J. (1996) Mol. Endocrinol. 10, 1147-1159
18. Narayan, P., Wu, C., and Puett, D. (1995) Mol. Endocrinol. 9, 1720-1726
19. Sugahara, T., Pixley, M. R., Minami, S., Perlas, E., Ben-Menahem, D., Hsueh, A. J., and Boime, I. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 2041-2045
20. Narayan, P., Gray, J., and Puett, D. (1996) Mol. Cell. Endocrinol. 117, 95-100
21. Magnusson, S., Petersen, T. E., Sottrup-Jensen, L., and Claey, H. (1975) in Protease and Biological Control (Reich, E., Rifkin, D. B., and Shaw, E. eds) pp. 123-149, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
22. Huang, J., and Puett, D. (1995) J. Biol. Chem. 270, 30023-30028
23. Fernandez, L. M., and Puett, D. (1996) J. Biol. Chem. 271, 925-930
24. Sugahara, T., Sato, A., Kudo, M., Ben-Menahem, D., Pixley, M. R., Hsueh, A. J. W., and Boime, I. (1996) J. Biol. Chem. 271, 10445-10448
25. Chen, F., Wang, Y., and Puett, D. (1991) J. Biol. Chem. 266, 19357-19361
26. Chen, F., Wang, Y., and Puett, D. (1992) Mol. Endocrinol. 6, 914-919
27. Xia, H., Chen, F., and Puett, D. (1994) Endocrinology 134, 1768-1770
28. Fernandez, L. M., and Puett, D. (1996) Biochemistry 35, 3986-3993