Comparative Evaluation of Ultrastructural Changes in Articular Cartilage of Ofioxacin-Treated and Magnesium-Deficient Immature Rats

Toxicologic Pathology

Volumn 24, Issue 5, 1996, Pages 580-587

  Shakibaei, Mehdi ^a   Kociok, Katja ^a   Förster, Christian ^a   Vormann, Jürgen ^a   Günther, Theodor ^a   Stahlmann, Ralf ^a   Merker, Hans Joachim ^a  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

chondrocytes; electron microscopy; magnesium; Quinolone induced arthropathy

Indexed keywords

MAGNESIUM; OFLOXACIN;

ANIMAL MODEL; ANIMAL TISSUE; ARTHROPATHY; ARTICLE; ARTICULAR CARTILAGE; ATOMIC ABSORPTION SPECTROMETRY; CARTILAGE CELL; CONTROLLED STUDY; MAGNESIUM DEFICIENCY; MICROSCOPY; NONHUMAN; PRIORITY JOURNAL; RAT; TRANSMISSION ELECTRON MICROSCOPY; ULTRASTRUCTURE;

AGING; ANIMALS; CARTILAGE, ARTICULAR; KNEE JOINT; MAGNESIUM DEFICIENCY; OFLOXACIN; QUINOLONES; RATS; RATS, WISTAR;

ANIMALIA;

EID: 0029854765     PISSN: 01926233     EISSN: None     Source Type: Journal    
DOI: 10.1177/019262339602400507     Document Type: Article

References (48)

1. Adam D. (1989). Use of quinolones in pediatric patients. Rev. Infect. Dis. 11 (suppl. 5): 1113-1116.
2. Burkhardt JE, Hill MA, and Carlton WW (1992). Morphologic and biochemical changes in articular cartilages of immature beagle dogs dosed with difloxacin. Toxicol. Pathol. 20: 246-252.
3. Burkhardt JE, Hill MA, Carlton WW, and Kesterson JW (1990). Histologic and histochemical changes in articular cartilage of immature beagle dogs dosed with difloxacin, a fluoroquinolone. Vet. Pathol. 27: 162-170.
4. Burkhardt JE, Hill MA, Lamar CH, Smith GN, and Carlton WW (1993). Effects of difloxacin on the metabolism of glycosaminoglycans and collagen in organ cultures of articular cartilage. Fund. Appl. Toxicol. 20: 257-263.
5. Burkhardt JE, Hill MA, Turek JJ, and Carlton WW (1992). Ultrastructural changes in articular cartilages of immature beagle dogs dosed with difloxacin, a fluoroquinolone. Vet. Pathol. 29: 230-238.
6. Carlson CS, Hilley HD, and Henrikson CK (1985). Ultrastructure of normal epiphyseal cartilage of the articular epiphyseal cartilage complex in growing swine. Am. J. Vet. Res. 46: 306-313.
7. Chevalier X., Albengres E., Voisin M-C., Tillement J-P., Larget-Piet B. (1992). A case of destructive polyarthropathy in a 17-year-old youth following pefloxacin treatment. Drug Safety 7: 310-314.
8. Dinarello CA, Cannon JG, Wolff SM, Bernheim HA, Beutler B., Cerami A., Figari IS, Palladino MA Jr, O'Connor JV (1986). Tumor necrosis factor (catectin) is an endogenous pyrogen and induces interleukin-1. J. Exp. Med. 163: 1433-1450.
9. Dingle JT, Page TPD, King B., and Bard DR (1987). In vivo studies of articular tissue damage mediated by catabolin/interleukin 1. Ann. Rheum. Dis. 46: 527-533.
10. Dürr J., Goodman S., Potocnik A., von der Mark H., and von der Mark K. (1993). Localization of β1-integrins in human cartilage and their role in chondrocyte adhesion to collagen and fibronectin. Exp. Cell Res. 207: 235-244.
11. Enomoto M., Leboy PS, Menko AS, and Boettiger D. (1993). β1-integrins mediate chondrocyte interaction with type I collagen, type II collagen, and fibronectin. Exp. Cell Res. 205: 276-285.
12. Förster C., Kociok K., Shakibaei M., Merker HJ, Vormann J., Günther T., and Stahlmann R. (1996). Integrins on joint cartilage chondrocytes and alterations by ofloxacin or magnesium deficiency in immature rats. Arch. Toxicol. 70: 261-270.
13. Gough AW, Kasali OB, Sigler RE, and Baragi V. (1992). Quinolone arthropathy-Acute toxicity to immature cartilage. Toxicol. Pathol. 20: 436-450.
14. Günther T., Schümann K., and Vormann J. (1995). Tumor necrosis factor-Â, prostanoids and immunoglobulins in magnesium deficiency. Magnes. Bull. 17: 109-114.
15. Henderson B. and Pettipher ER (1989). Arthritogenic actions of recombinent IL-1 and tumor necrosis factor in the rabbit: Evidence for synergistic interactions between cytokines in vivo. Clin. Exp. Immunol. 75: 306-310.
16. Hewitt AT, Varner HH, Silver MH, Dessau W., Wilkes CM, and Martin GR (1982). The isolation and partial characterization of chondronectin, an attachment factor for chondrocytes. J. Cell Biol. 257: 2330-2334.
17. Kato M. and Onodera T. (1988). Effect of ofloxacin on the uptake of [3H] thymidine by articular cartilage cells in the rat. Toxicol. Lett. 44: 131-142.
18. Kato M. and Onodera T. (1988). Morphological investigation of cavity formation in articular cartilage induced by ofloxacin in rats. Fund. Appl. Toxicol. 11: 110-119.
19. Kato M., Takada S., Ogawara S., and Takayama S. (1995). Effect of levofloxacin on glycosaminoglycan and DNA synthesis of cultured rabbit chondrocytes at concentrations inducing cartilage lesions in vivo. Antimicrob. Agents Chemother. 39: 1979-1983.
20. Kosher RA and Church RL (1975). Stimulation of in vitro somite chondrogenesis by procollagen and collagen. Nature (London) 258: 327-330.
21. Kosher RA, Lash JW, and Minor RR (1973). Environmental enhancement of in vitro chondrogenesis. IV. Stimulation of somite chondrogenesis by exogenous chondromucoprotein. Dev. Biol. 35: 210-220.
22. Landis WJ and Hodgens KJ (1990). Visualization of sulfur-containing components associated with proliferating chondrocytes from rat epiphyseal growth plate cartilage: possible proteoglycan and collagen co-migration. Anat. Rec. 226: 153-167.
23. Loeser RF (1993). Integrin-mediated attachment of articular chondrocytes to extracellular matrix proteins. Arthritis Rheum. 36: 1103-1110.
24. Loeser RF (1994). Modulation of integrin mediated attachment of chondrocytes to extracellular matrix proteins by cations, retinoic acid and transforming growth factor β. Exp. Cell Res. 211: 17-23.
25. Mohamed-Ali H. (1995). Influence of interleukin-1β, tumour necrosis factor alpha and prostaglandin E2 on chondrogenesis and cartilage matrix breakdown in vitro. Rheumatol. Int. 14: 191-199.
26. Nawroth PP, Bank I., Handley D., Cassimeris J., Chess L., and Stern D. (1986). Tumor necrosis factor/cachectin interacts with endothelial cell receptors to induce release of interleukin 1. J. Exp. Med. 163: 1363-1375.
27. Neu HC (1992). Quinolone antimicrobial agents. Ann. Rev. Med. 43: 465-486.
28. Okazaki O., Kurata T., Hashimoto K., Sudo K., Tsumura M., and Tachizawa H. (1984). Metabolic disposition of DL-8280. The second report: Absorption, distribution and excretion of 14C-DL-8280 in various animal species. Chemotherapy 32(suppl. 1): 1185-1202.
29. Pettipher ER, Higgs GA, and Henderson B. (1986). Interleukin 1 induces leukocyte infiltration and cartilage proteoglycan degradation in the synovial joint. Proc. Natl. Acad. Sci. USA 83: 8749-8753.
30. Ramachandrula A., Tiku K., and Tiku ML (1992). Tripeptide RGDdependent adhesion of articular chondrocytes to synovial fibroblasts. J. Cell Biol. 101: 859-871.
31. Ross DL and Riley M. (1993). Physicochemical properties of the fluoroquinolone antimicrobials V. Effect of fluoroquinolone structure and pH on the complexation of various fluoroquinolones with magnesium and calcium ions. Int. J. Pharm. 93: 121-129.
32. Saklatvala J. (1986). Tumor necrosis factor α stimulates resorption and inhibits synthesis of proteoglycan in cartilage. Nature (London) 322: 547-549.
33. Salter DM, Hughes DE, Simpson R., and Gardner DL (1992). Integrin expression by human articular chondrocytes. Brit. J. Rheumat. 31: 231-234.
34. Samuelson WM, Pleasants RA, and Whitaker MS (1993). Arthropathy secondary to ciprofloxacin in an adult cystic fibrosis patient. Ann. Pharmacother. 27: 302-303.
35. Schaad UB (1992). Role of the new quinolones in pediatric practice. Pediatr. Infect. Dis. J. 11: 1043-1046.
36. Schaad UB and Wedgwood J. (1992). Lack of quinolone-induced arthropathy in children. J. Antimicrob. Chemoth. 30: 414-416.
37. Shakibaei M., Abou-Rebyeh H., and Merker H-J. (1993). Integrins in ageing cartilage tissue in vitro. Histol. Histopathol. 8: 715-723.
38. Shakibaei M., Förster C., Merker H-J., and Stahlmann R. (1995). Effects of ofloxacin on integrin expression on epiphyseal mouse chondrocytes in vitro. Toxic. Vitro 9: 107-116.
39. Shakibaei M., Zimmermann B., and Merker H. -J. (1995). Changes in integrin expression during chondrogenesis in vitro (an immunomorphological study). J. Histochem. Cytochem. 43: 1061-1069.
40. Sommarin Y., Larsson T., and Heinegard D. (1989). Chondrocyte-matrix interactions: Attachment to proteins isolated from cartilage. Exp. Cell Res. 184: 181-192.
41. Stahlmann R. (1990). Safety profile of the quinolones. J. Antimicrob. Chemother. 26(suppl. D): 31-44.
42. Stahlmann R., Förster C., Shakibaei M., Vormann J., Günther T., and Merker H. -J. (1995). Magnesium deficiency induces joint cartilage lesions in juvenile rats which are identical with quinolone-induced arthropathy. Antimicrob. Agents Chemother. 39: 2013-2018.
43. Stahlmann R., Förster C., and Van Sickle D. (1993). Quinolones in children: Are concerns over arthropathy justified? Drug Safety 9: 397-403.
44. Stahlmann R., Merker H. -J., Hinz N., Chahoud I., Webb J., Heger W., and Neubert D. (1990). Ofloxacin in juvenile non-human primates and rats. Arthropathia and drug plasma concentrations. Arch. Toxicol. 64: 193-204.
45. Tatsumi H., Senda H., Yatera S., Takemoto Y., Yamayoshi M., and Ohnishi K. (1978). Toxicological studies on pipemidic acid, V. Effect on diarthrodial joints of experimental animals. J. Toxicol. Sci. 3: 357-367.
46. Weglicki WB, Stafford RE, Dickens BF, Mak IT, Cassidy MM, and Phillips TM (1993). Inhibition of tumor necrosis factor-alpha by thalidomide in magnesium deficiency. Mol. Cell. Biochem. 129: 195-200.
47. Woessner JF Jr (1991). Matrix metalloproteinases and their inhibitors in connective tissue remodeling. FASEB 5: 2145-2154.
48. Woods VL Jr, Schreck PL, Gesink DS, Pacheco HO, Amiel D., Akeson WH, and Lotz M. (1994). Intergrin expression by human articular chondrocytes. Arthritis Rheum. 37: 537-544.