Structural and functional conservation of the Drosophila doublesex splicing enhancer repeat elements

RNA

Volumn 2, Issue 10, 1996, Pages 969-981

  Hertel, Klemens J ^a   Lynch, Kristen W ^a   Hsiao, Edward C ^a   Liu, Eric H T ^a   Maniatis, Tom ^a  

^a HARVARD UNIVERSITY   (United States)

Author keywords

phylogeny; regulated splicing; RNA structure; RNA protein interactions

Indexed keywords

ARTICLE; DROSOPHILA; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROTEIN RNA BINDING; RNA SEQUENCE; RNA SPLICING; RNA STRUCTURE;

ALTERNATIVE SPLICING; ANIMALS; BASE SEQUENCE; CONSERVED SEQUENCE; DNA-BINDING PROTEINS; DROSOPHILA; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; ENHANCER ELEMENTS (GENETICS); EXONS; FEMALE; HELA CELLS; HUMANS; INSECT HORMONES; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; OLIGONUCLEOTIDES, ANTISENSE; REPETITIVE SEQUENCES, NUCLEIC ACID; RIBONUCLEOPROTEINS; RNA; SEQUENCE ANALYSIS, DNA;

DROSOPHILA MELANOGASTER; DROSOPHILA VIRILIS; MELANOGASTER;

EID: 0029853580     PISSN: 13558382     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Amrein H, German M, Nöthiger R. 1988. The sex-determining gene tra-2 of Drosophila encodes a putative RNA binding protein. Cell 55:1025-1035.
2. Amrein H, Medley ML, Maniatis T. 1994. The role of specific protein-RNA and protein-protein interactions in positive and negative control of pre-mRNA splicing by Transformer 2. Cell 76:735-746.
3. Baker BS. 1989. Sex in flies: The splice of life. Nature 340:521-524.
4. Bandziulis RJ, Swanson MS, Dreyfuss G. 1989. RNA-binding proteins as developmental regulators. Genes & Dev 3:431-437.
5. Blackman RK, Meselson M. 1986. Interspecific nucleotide sequence comparisons used to identify regulatory and structural features of the Drosophila hsp82 gene. J Mol Biol 188:499-515.
6. Boggs RT, Gregor P, Idriss S, Belote JM, McKeown M. 1987. Regulation of sexual differentiation in D. melanogaster via alternative splicing of RNA from the transformer gene. Cell 50:739-747.
7. Burtis KC, Baker BS. 1989. Drosophila doublesex gene controls somatic sexual differentiation by producing alternative spliced mRNAs encoding related sex-specific polypeptides. Cell 56:997-1010.
8. Conway L, Wickens M. 1989. Modification interference analysis of reactions using RNA substrates. Methods Enzymol 380:369-379.
9. Dominski Z, Kole R. 1994. Identification of exon sequences involved in splice site selection. J Biol Chem 269:23590-23596.
10. Fu XD. 1995. The superfamily of arginine/serine-rich splicing factors. RNA 2:663-680.
11. Gott JM, Pan T, LeCuyer KA, Uhlenbeck OC. 1993. Using circular permutation analysis to redefine the R17 coat protein binding site. Biochemistry 32:13399-13404.
12. Hedley ML, Maniatis T. 1991. Sex-specific splicing and polyadenylation of dsx pre-mRNA requires a sequence that binds specifically to tra-2 protein in vitro. Cell 65:579-586.
13. Heinrichs V, Baker BS. 1995. The Drosophila SR protein RBP1 contributes to the regulation of doublesex alternative splicing by recognizing RBP1 RNA target sequences. EMBO J 16:3987-4000.
14. Hoshijima K, Inoue K, Higuchi I, Sakamoto H, Shimura Y. 1991. Control of doublesex alternative splicing by transformer and transfonner-2 in Drosophila. Science 252:833-836.
15. Inoue K, Hoshijima K, Higuchi I, Sakamoto H, Shimura Y. 1992. Binding of the Drosophila Transformer and Transformer-2 proteins to the regulatory elements of doublesex primary transcripts for sex-specific RNA processing. Proc Natl Acad Sci USA 89:8092-8096.
16. Jaeger JA, Turner DH, Zuker M. 1989. Improved predictions of secondary structures for RNA. Proc Natl Acad Sci USA 86:7706-7710.
17. Knapp G. 1989. Enzymatic approaches to probing of RNA secondary and tertiary structure. Methods Enzymol 180:192-212.
18. Krol A, Carbon P. 1989. A guide for probing native small nuclear RNA and ribonucleoprotein structures. Methods Enzymol 180:212-227.
19. Lynch KW, Maniatis T. 1995. Synergistic interactions between two distinct elements of a regulated splicing enhancer. Genes & Dev 9:284-293.
20. Lynch KW, Maniatis T. 1996. Assembly of specific SR protein complexes on distinct regulatory elements of the Drosophila doublesex splicing enhancer. Genes & Dev 10:2089-2101.
21. Maniatis T. 1991. Mechanisms of alternative pre-mRNA splicing. Science 251:33-34.
22. Nagai K, Oubridge C, Ito N, Avis J, Evans P. 1995. The RNP domain: A sequence-specific RNA binding domain involved in processing and transport of RNA. Trends Biochem Sci 20:235-240.
23. Newfeld SJ, Smoller DA, Yedvobnick B. 1991. Interspecific comparison of the unusually repetitive Drosophila locus mastermind. J Mot Evol 32:415-420.
24. Noller HF. 1984. Structure of ribosomal RNA. Annu Rev Biochem 53:119-162.
25. O'Neil MT, Belote JM. 1992. Interspecific comparison of the transformer gene of Drosophila reveals an unusually high degree of evolutionary divergence. Genetics 131:113-128.
26. Oubridge C, Ito N, Evans PR, Teo C-H, Nagai K. 1994. Crystal structure at 1.92 A resolution of the RNA-binding domain of the U1A spliceosomal protein complexed with an RNA hairpin. Nature 372:432-438.
27. Ramchatesingh J, Zahler AM, Neugebauer KM, Roth MB, Cooper TA. 1995. A subset of SR proteins activates splicing of the cardiac troponin T alternative exon by direct interactions with an exonic enhancer. Mol Cell Biol 9:4898-4907.