New insight into the mechanisms of ethanol effects on GABA(A) receptor function and expression, and their relevance to behavior

Alcoholism: Clinical and Experimental Research

Volumn 20, Issue 8 SUPPL., 1996, Pages

  Buck, Kari J ^a   Reynolds, James N ^b  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b QUEEN S UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; ALCOHOL; RECEPTOR SUBUNIT;

ALCOHOL ABUSE; BEHAVIOR; CONFERENCE PAPER; GENE CLUSTER; GENE LOCUS; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; QUANTITATIVE TRAIT;

EID: 0029852074     PISSN: 01456008     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1530-0277.1996.tb01776.x     Document Type: Conference Paper

References (16)

1. Little HJ: Mechanisms that may underlie the behavioural effects of ethanol. Prog Neurobiol 36:171-194, 1991
2. A receptor channels. Ann Rev Neurosci 17:569-602, 1994
3. 2 subunit FEBS Lett 313:113-117, 1992
4. McCreery MJ, Hunt WA: Physico-chemical correlates of alcohol intoxication. Neuropharmacol 17:451-461, 1978
5. Aguayo LG, Pancetti PC: Ethanol modulation of the γ-aminobutyric acid A- and glycine-activated chloride current in cultured mouse neurons. J Pharmacol Exp Ther 270:61-69, 1994
6. Harris RA, McQuilkin SJ, Paylor R, Abeliovich A, Tonegawa S, Wehner JM: Mutant mice lacking the γ isoform of protein kinase C show decreased behavioral actions of ethanol and altered function of γaminobutyrate type A receptors. Proc Natl Acad Sci USA 92:3658-3662, 1995
7. Lin AM-Y, Bickford PC, Palmer MR: The effects of ethanol on γ-aminobutyric acid-induced depressions of cerebellar Purkinje neurons: Influence of beta-adrenergic receptor action in young and aged Fischer 344 rats. J Pharmacol Exp Ther 264: 951-957, 1993
8. A mediated synaptic current by ethanol in hippocampal CA1 neurons: possible role of protein kinase C. J Pharmacol Exp Ther 268:1388-1395, 1994
9. A receptors expressed in mammalian cells and Xenopus oocytes. (submitted)
10. A receptors in rat hippocampal CA1 neurons: Role of PKC. (submitted)
11. Nissim A, Hoogenboom HR, Tomlinson IM, Flynn G, Midgley C, Lane D, Winter G: Antibody fragments from a single pot phage display library asimmunochemical reagents. EMBO J 13:692-698, 1994
12. Buck KJ, Metten P, Belknap JK, Crabbe JC: Loci influencing genetic predisposition to acute alcohol dependence and withdrawal map to murine chromosomes 1, 4, and 11. (submitted)
13. Belknap JK, Mitchell SR, O'Toole LA, Helms ML, Crabbe JC: Type I and type II error rates for quantitative trait loci (QTL) mapping studies using recombinant inbred mouse strains. Behav Genet 26:149-160, 1996
14. Lander ES, Kruglyak L: Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results. Nature Genet 11:241-247, 1995
15. A receptor subunit mRNAs: Relationship to genetic differences in ethanol withdrawal seizure severity. J Neurochem 57:1452-1455, 1991
16. A receptor-operated chloride channels by benzodiazepine inverse agonists is related to genetic differences in ethanol withdrawal seizure severity, J Neurochem 57:2100-2105, 1991