메뉴 건너뛰기




Volumn 9, Issue 4, 1996, Pages 188-198

Multiple autoantigens in the prediction and pathogenesis of Type I diabetes

Author keywords

Autoantibodies; Diabetes risk; Prediction insulin autoantigen; Type I diabetes

Indexed keywords

AUTOANTIBODY; AUTOANTIGEN; GLUTAMATE DECARBOXYLASE; INSULIN; PHOGRIN; UNCLASSIFIED DRUG;

EID: 0029849210     PISSN: 03943402     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (8)

References (98)
  • 1
    • 0003028228 scopus 로고
    • Pathogenesis of insulin-dependent (type I) diabetes mellitus
    • Weir, Kahn C.R., (Eds.), Philadelphia. Lea & Febiger.
    • Eisenbarth G.S., Ziegler A., Colman P.: Pathogenesis of insulin-dependent (type I) diabetes mellitus. In: Weir, Kahn C.R., (Eds.), Joslin's diabetes mellitus. 13th ed. Philadelphia. Lea & Febiger. 1994 pp. 216-239.
    • (1994) Joslin's Diabetes Mellitus. 13th Ed. , pp. 216-239
    • Eisenbarth, G.S.1    Ziegler, A.2    Colman, P.3
  • 2
    • 0026627765 scopus 로고
    • Insulin autoantibodies measured by radioimmunoassay methodology are more related to insulin-dependent diabetes mellitus than those measured by enzyme-linked immunosorbent assay: Results of the fourth international workshop on the standardization of insulin autoantibody measurement
    • Greenbaum C., Palmer J.P., Kuglin B., Kolb H., and Participating Laboratories: Insulin autoantibodies measured by radioimmunoassay methodology are more related to insulin-dependent diabetes mellitus than those measured by enzyme-linked immunosorbent assay: Results of the fourth international workshop on the standardization of insulin autoantibody measurement. J. Clin. Endocrinol. Metab. 74 1040-1044. 1992.
    • (1992) J. Clin. Endocrinol. Metab. , vol.74 , pp. 1040-1044
    • Greenbaum, C.1    Palmer, J.P.2    Kuglin, B.3    Kolb, H.4
  • 4
    • 0025841845 scopus 로고
    • Identification and cloning of a granule autoantigen (carboxypeptidase H) associated with Type I diabetes
    • Castano L., Russo E., Zhou L., Lipes M.A., Eisenbarth G.S.: Identification and cloning of a granule autoantigen (carboxypeptidase H) associated with Type I diabetes. J Clin. Endocrinol. Metab. 73: 1197-1201, 1991.
    • (1991) J Clin. Endocrinol. Metab. , vol.73 , pp. 1197-1201
    • Castano, L.1    Russo, E.2    Zhou, L.3    Lipes, M.A.4    Eisenbarth, G.S.5
  • 6
    • 0029144683 scopus 로고
    • GM2-1 pancreatic islet ganglioside: Identification and characterization of a novel islet-specific molecule
    • Dotta F., Previti, M., Lenti L., Dionisi S., Casetta B., D'Erme M., Eisenbarth G., Di Mario U.: GM2-1 pancreatic islet ganglioside: identification and characterization of a novel islet-specific molecule. Diabetologia 38: 1117-1121, 1995.
    • (1995) Diabetologia , vol.38 , pp. 1117-1121
    • Dotta, F.1    Previti, M.2    Lenti, L.3    Dionisi, S.4    Casetta, B.5    D'Erme, M.6    Eisenbarth, G.7    Di Mario, U.8
  • 8
    • 0027930455 scopus 로고
    • Molecular cloning and identification of a receptor-type protein tyrosine phosphatase, IA-2. from human insulinoma
    • Lan M.S., Lu J., Goto Y., Notkins A.L.: Molecular cloning and identification of a receptor-type protein tyrosine phosphatase, IA-2. from human insulinoma. DNA and Cell Biology 13:505-514, 1994.
    • (1994) DNA and Cell Biology , vol.13 , pp. 505-514
    • Lan, M.S.1    Lu, J.2    Goto, Y.3    Notkins, A.L.4
  • 9
    • 10244228879 scopus 로고
    • Molecular cloning of an insulin secretory granule protein tyrosine phosphatase
    • Abstract
    • Wasmeier C., Hutton J.C.: Molecular cloning of an insulin secretory granule protein tyrosine phosphatase. Diabetologia 38: A69, 1995 (Abstract).
    • (1995) Diabetologia , vol.38
    • Wasmeier, C.1    Hutton, J.C.2
  • 10
    • 0027363484 scopus 로고
    • Islet cell autoantigens in insulin-dependent diabetes
    • Atkinson M.A., Maclaren N.K.: Islet cell autoantigens in insulin-dependent diabetes. J. Clin. Invest. 92: 1608-1616, 1993.
    • (1993) J. Clin. Invest. , vol.92 , pp. 1608-1616
    • Atkinson, M.A.1    Maclaren, N.K.2
  • 12
    • 0025738117 scopus 로고
    • Two genes encode distinct glutamate decarboxylases with different responses to pyridoxal phosphate
    • Erlander M.G., Tillakaratne N.J.K., Feldblum S., Patel N., Tobin A.J.: Two genes encode distinct glutamate decarboxylases with different responses to pyridoxal phosphate. Neuron 7: 91-100, 1991.
    • (1991) Neuron , vol.7 , pp. 91-100
    • Erlander, M.G.1    Tillakaratne, N.J.K.2    Feldblum, S.3    Patel, N.4    Tobin, A.J.5
  • 13
    • 0026027134 scopus 로고
    • Two forms of the gamnia-aminobutyric acid synthetic enzyme glutamate decarboxylase have distinct intraneuronal distributions and cofactor interactions
    • Kaufman D.L., Houser C.R., Tobin A.J.: Two forms of the gamnia-aminobutyric acid synthetic enzyme glutamate decarboxylase have distinct intraneuronal distributions and cofactor interactions. J. Neurochem. 56: 720-723, 1991.
    • (1991) J. Neurochem. , vol.56 , pp. 720-723
    • Kaufman, D.L.1    Houser, C.R.2    Tobin, A.J.3
  • 15
    • 0027524041 scopus 로고
    • Human autoantibodies react with glutamic acid decarboxylase antigen in human and rat but not in mouse pancreatic islets
    • Velloso L.A., Kampe O., Eizirik D.L., Hallberg A., Andersson A., Karlsson F.A.: Human autoantibodies react with glutamic acid decarboxylase antigen in human and rat but not in mouse pancreatic islets. Diabetologia 36: 39-46, 1993.
    • (1993) Diabetologia , vol.36 , pp. 39-46
    • Velloso, L.A.1    Kampe, O.2    Eizirik, D.L.3    Hallberg, A.4    Andersson, A.5    Karlsson, F.A.6
  • 17
    • 0001000551 scopus 로고
    • Progressive fluctuating muscular rigiditiy and spasm (stiff-man syndrome) report of a case and some observations in 13 other cases
    • Moersch F.P., Woltman H.W.: Progressive fluctuating muscular rigiditiy and spasm (stiff-man syndrome) report of a case and some observations in 13 other cases. Mayo Clin. Proc. 31: 421-427, 1956.
    • (1956) Mayo Clin. Proc. , vol.31 , pp. 421-427
    • Moersch, F.P.1    Woltman, H.W.2
  • 18
    • 0026016007 scopus 로고
    • Stiff-person syndrome: An autoimmune disease
    • Blum P., Jankovic J.: Stiff-person syndrome: An autoimmune disease. Movement Disorder.1, 6: 12-20, 1991.
    • (1991) Movement Disorder.1 , vol.6 , pp. 12-20
    • Blum, P.1    Jankovic, J.2
  • 19
    • 0025793748 scopus 로고
    • Stiff-man syndrome
    • McEvoy KM: Stiff-man syndrome. Mayo Clin. Proc. 66: 300-304, 1991.
    • (1991) Mayo Clin. Proc. , vol.66 , pp. 300-304
    • McEvoy, K.M.1
  • 20
    • 0025362089 scopus 로고
    • Autoantibodies to GABA-ergic neurons and pancreatic beta cells in Stiff-Man syndrome
    • Solimena M., Folli F., Aparisi R., Pozza G., DeCamilli P.: Autoantibodies to GABA-ergic neurons and pancreatic beta cells in Stiff-Man syndrome. N. Engl. J. Med. 322: 1555-1560, 1990.
    • (1990) N. Engl. J. Med. , vol.322 , pp. 1555-1560
    • Solimena, M.1    Folli, F.2    Aparisi, R.3    Pozza, G.4    DeCamilli, P.5
  • 21
    • 0025781922 scopus 로고
    • Autoimmunity to glutamic acid decarboxylase (GAD) in Stiff-man syndrome and insulin-dependent diabetes mellitus
    • Solimena M., DeCamilli P.: Autoimmunity to glutamic acid decarboxylase (GAD) in Stiff-man syndrome and insulin-dependent diabetes mellitus. Trends in Neurosciences 14: 452-457, 1991.
    • (1991) Trends in Neurosciences , vol.14 , pp. 452-457
    • Solimena, M.1    DeCamilli, P.2
  • 22
    • 0025009438 scopus 로고
    • Stiffman syndrome: A GABAergic autoimmune disorder with autoantigenic heterogeneity
    • Gorin F., Baldwin B., Tait R., Pathak R., Seyal M.: Stiffman syndrome: a GABAergic autoimmune disorder with autoantigenic heterogeneity. Ann. Neurol. 28: 711-714, 1990.
    • (1990) Ann. Neurol. , vol.28 , pp. 711-714
    • Gorin, F.1    Baldwin, B.2    Tait, R.3    Pathak, R.4    Seyal, M.5
  • 23
    • 0019959221 scopus 로고
    • Autoantibodies in newly diagnosed diabetic children immunoprecipitate specific human islet cell proteins
    • Baekkeskov S., Nielsen J.H., Marner B., Bilde T., Ludvigsson J., Lernmark A.: Autoantibodies in newly diagnosed diabetic children immunoprecipitate specific human islet cell proteins. Nature 298: 167-169, 1982.
    • (1982) Nature , vol.298 , pp. 167-169
    • Baekkeskov, S.1    Nielsen, J.H.2    Marner, B.3    Bilde, T.4    Ludvigsson, J.5    Lernmark, A.6
  • 25
    • 0025194668 scopus 로고
    • 64000 Mr autoantibodies as predictors of insulin-dependent diabetes
    • Atkinson M.A., Maclaren N.K., Scharp D.W., Lacy P.E., Riley W.J.: 64000 Mr autoantibodies as predictors of insulin-dependent diabetes. Lancet 335: 1357-1360, 1990.
    • (1990) Lancet , vol.335 , pp. 1357-1360
    • Atkinson, M.A.1    Maclaren, N.K.2    Scharp, D.W.3    Lacy, P.E.4    Riley, W.J.5
  • 26
    • 0027311069 scopus 로고
    • Demonstration of GAD-65 as the main immunogenic isoform of glutamate decarboxylase in Type I diabetes and determination of autoantibodies using a radioligand produced by eukaryotic expression
    • Velloso L.A., Kampe O., Hallberg A., Christmanson L., Betsholtz C., Karlsson F.A.: Demonstration of GAD-65 as the main immunogenic isoform of glutamate decarboxylase in Type I diabetes and determination of autoantibodies using a radioligand produced by eukaryotic expression. J. Clin. Invest. 91: 2084-2090, 1993.
    • (1993) J. Clin. Invest. , vol.91 , pp. 2084-2090
    • Velloso, L.A.1    Kampe, O.2    Hallberg, A.3    Christmanson, L.4    Betsholtz, C.5    Karlsson, F.A.6
  • 28
    • 0027340217 scopus 로고
    • Characterization of a linear epitope within the human pancreatic 64-kDa glutamic acid decarboxylase and its autoimmune recognition by sera from insulin-dependent diabetes mellitus patients
    • Mauch L., Abney C.C., Berg H., Scherbaum W.A., Liedvogel B., Northemann W.: Characterization of a linear epitope within the human pancreatic 64-kDa glutamic acid decarboxylase and its autoimmune recognition by sera from insulin-dependent diabetes mellitus patients. Eur. J. Biochem. 212: 597-603, 1993.
    • (1993) Eur. J. Biochem. , vol.212 , pp. 597-603
    • Mauch, L.1    Abney, C.C.2    Berg, H.3    Scherbaum, W.A.4    Liedvogel, B.5    Northemann, W.6
  • 30
    • 0028928952 scopus 로고
    • Two distinct glutamic acid decarboxylase autoantibody specificities in IDDM target different epitopes
    • Daw K., Powers A.C.: Two distinct glutamic acid decarboxylase autoantibody specificities in IDDM target different epitopes. Diabetes 44: 216-220, 1995.
    • (1995) Diabetes , vol.44 , pp. 216-220
    • Daw, K.1    Powers, A.C.2
  • 31
    • 0030028799 scopus 로고    scopus 로고
    • Glutamic acid decarboxylase autoantibodies in Stiff-man syndrome and insulin-dependent diabetes meilitus exhibit similarities and differences in epitope recognition
    • Daw K., Ujihara N., Atkinson M., Powers A.C.: Glutamic acid decarboxylase autoantibodies in Stiff-man syndrome and insulin-dependent diabetes meilitus exhibit similarities and differences in epitope recognition. J. Immunol. 156: 818-825, 1996.
    • (1996) J. Immunol. , vol.156 , pp. 818-825
    • Daw, K.1    Ujihara, N.2    Atkinson, M.3    Powers, A.C.4
  • 32
    • 0028989040 scopus 로고
    • HLADQB1 0602 is associated with dominant protection from diabetes even among isiet cell antibody positive first degree relatives of patients with insulin-dependent diabetes
    • Pugliese A., Gianani R., Moromisato R., Awdeh Z.L., Alper C A., Erlich H.A., Jackson R.A., Eisenbarth G.S.: HLADQB1 0602 is associated with dominant protection from diabetes even among isiet cell antibody positive first degree relatives of patients with insulin-dependent diabetes. Diabetes 44: 608-613, 1995.
    • (1995) Diabetes , vol.44 , pp. 608-613
    • Pugliese, A.1    Gianani, R.2    Moromisato, R.3    Awdeh, Z.L.4    Alper, C.A.5    Erlich, H.A.6    Jackson, R.A.7    Eisenbarth, G.S.8
  • 33
    • 0028132553 scopus 로고
    • Identification of glutamic acid decarboxylase autoantibody heterogeneity and epitope regions in Type I diabetes
    • Ujihara N., Daw K., Gianani R., Boel E., Yu L., Powers A.C. Identification of glutamic acid decarboxylase autoantibody heterogeneity and epitope regions in Type I diabetes. Diabetes 43: 968-975, 1994.
    • (1994) Diabetes , vol.43 , pp. 968-975
    • Ujihara, N.1    Daw, K.2    Gianani, R.3    Boel, E.4    Yu, L.5    Powers, A.C.6
  • 35
    • 0027908753 scopus 로고
    • Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice
    • Tisch R., Yang X., Singer S.M., Liblau R.S., Fugger L., McDevitt H.O.: Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice. Nature 366: 72-75, 1993.
    • (1993) Nature , vol.366 , pp. 72-75
    • Tisch, R.1    Yang, X.2    Singer, S.M.3    Liblau, R.S.4    Fugger, L.5    McDevitt, H.O.6
  • 36
    • 0027176158 scopus 로고
    • Inverse relationship between humoral and cellular immunity to glutamic acid decarboxylase in subjects at risk of insulin-dependent diabetes
    • Harrison L.C., Honeyman M.C., De Aizpurua H.J., Schmidli R.S., Colman P.G., Tait B.D., Cram D.S.: Inverse relationship between humoral and cellular immunity to glutamic acid decarboxylase in subjects at risk of insulin-dependent diabetes. Lancet 341: 1365-1369, 1993.
    • (1993) Lancet , vol.341 , pp. 1365-1369
    • Harrison, L.C.1    Honeyman, M.C.2    De Aizpurua, H.J.3    Schmidli, R.S.4    Colman, P.G.5    Tait, B.D.6    Cram, D.S.7
  • 41
    • 0025050449 scopus 로고
    • Distinct antibody specificities to a 64-kD islet cell antigen in Type I diabetes as revealed by trypsin treatment
    • Christie M.R., Vohra G., Champagne P., Daneman D., Delovitch T.L.: Distinct antibody specificities to a 64-kD islet cell antigen in Type I diabetes as revealed by trypsin treatment. J. Exper. Med. 1990.
    • (1990) J. Exper. Med.
    • Christie, M.R.1    Vohra, G.2    Champagne, P.3    Daneman, D.4    Delovitch, T.L.5
  • 42
    • 0029120042 scopus 로고
    • Relationship of the 37,000- And 40,000-Mr tryptic fragments of islet antigens in insulin-dependent diabetes to the protein tyrosine phosphatase-like molecule IA-2 (ICA512)
    • Payton M.A., Hawkes C.J., Christie M.R.: Relationship of the 37,000- and 40,000-Mr tryptic fragments of islet antigens in insulin-dependent diabetes to the protein tyrosine phosphatase-like molecule IA-2 (ICA512). J. Clin. Invest. 96: 1506-1511, 1995.
    • (1995) J. Clin. Invest. , vol.96 , pp. 1506-1511
    • Payton, M.A.1    Hawkes, C.J.2    Christie, M.R.3
  • 43
    • 0028801042 scopus 로고
    • Identification of protein tyrosine phosphaiase-like IA2 (islet call antigen 512) as the insulin-dependent diabetes-related 37/40K autoantigen and a target of islet-cell antibodies
    • Bonifacio E., Lampasona V., Genovese S., Ferrari M., Bosi E.: Identification of protein tyrosine phosphaiase-like IA2 (islet call antigen 512) as the insulin-dependent diabetes-related 37/40K autoantigen and a target of islet-cell antibodies. J. Immunol. 155: 5419-5426, 1995.
    • (1995) J. Immunol. , vol.155 , pp. 5419-5426
    • Bonifacio, E.1    Lampasona, V.2    Genovese, S.3    Ferrari, M.4    Bosi, E.5
  • 44
    • 0029784457 scopus 로고    scopus 로고
    • Autoantibodies to protein tyrosine phosphatase-like proteins in Type I diabetes: Overlapping specificities to phogrin and ICA512/IA-2
    • in press
    • Kawasaki E., Eisenbarth G.S., Wasmeicr C., Hutton J.C.: Autoantibodies to protein tyrosine phosphatase-like proteins in Type I diabetes: Overlapping specificities to phogrin and ICA512/IA-2. Diabetes: in press 1996.
    • (1996) Diabetes
    • Kawasaki, E.1    Eisenbarth, G.S.2    Wasmeicr, C.3    Hutton, J.C.4
  • 46
    • 0027323779 scopus 로고
    • Characterization of insulin autoantibodies in relatives of patients with insulin-dependent diabetes mellitus
    • Castano L., Ziegler A., Ziegler R., Shoelson S., Eisenbarth G.S.: Characterization of insulin autoantibodies in relatives of patients with insulin-dependent diabetes mellitus. Diabetes 42: 1202-1209, 1993.
    • (1993) Diabetes , vol.42 , pp. 1202-1209
    • Castano, L.1    Ziegler, A.2    Ziegler, R.3    Shoelson, S.4    Eisenbarth, G.S.5
  • 49
    • 0028145676 scopus 로고
    • Insulin-specific T cells are a predominant component of islet infiltrates in pre-diabetic NOD mice
    • Wegmann D., Norbury-Glaser M., Daniel D.: Insulin-specific T cells are a predominant component of islet infiltrates in pre-diabetic NOD mice. Ear. J. Immunol. 24: 1853-1857, 1994.
    • (1994) Ear. J. Immunol. , vol.24 , pp. 1853-1857
    • Wegmann, D.1    Norbury-Glaser, M.2    Daniel, D.3
  • 51
    • 0028914351 scopus 로고
    • Epitope specificity, cytokine production profile and diabetogenic activity of insulin-specific T cell clones isolated from NOD mice
    • Daniel D., Gill R.G., Schloot N., Wegmann D.: Epitope specificity, cytokine production profile and diabetogenic activity of insulin-specific T cell clones isolated from NOD mice. Eur. J. Immunol. 25: 1056-1062, 1995.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 1056-1062
    • Daniel, D.1    Gill, R.G.2    Schloot, N.3    Wegmann, D.4
  • 52
    • 0026351576 scopus 로고
    • Autoantibodies to glutamic acid decarboxylase (GAD) detected by an immuno-trapping enzyme activity assay: Relation to insulin-dependent diabetes mellitus and islet cell antibodies
    • Martino G.V., Tappaz M.L., Braghi S., Dozio N., Canal N., Pozza G., Bottazzo G.F.: Autoantibodies to glutamic acid decarboxylase (GAD) detected by an immuno-trapping enzyme activity assay: relation to insulin-dependent diabetes mellitus and islet cell antibodies. J. Autoimmunity 4: 915-923, 1991.
    • (1991) J. Autoimmunity , vol.4 , pp. 915-923
    • Martino, G.V.1    Tappaz, M.L.2    Braghi, S.3    Dozio, N.4    Canal, N.5    Pozza, G.6    Bottazzo, G.F.7
  • 53
    • 0026632265 scopus 로고
    • Antibodies to glutamic acid decarboxylase discriminate major types of diabetes mellitus
    • Rowley M.J., Mackay I.R., Chen Q., Knowles W.J., Zimmet P.Z.: Antibodies to glutamic acid decarboxylase discriminate major types of diabetes mellitus. Diabetes 41: 548-551, 1992
    • (1992) Diabetes , vol.41 , pp. 548-551
    • Rowley, M.J.1    Mackay, I.R.2    Chen, Q.3    Knowles, W.J.4    Zimmet, P.Z.5
  • 57
    • 0026803258 scopus 로고
    • An ELISA for antibodies to recombinant glutamic acid decarboxylase in IDDM
    • DeAizpurua H.J., Harrison L.C., Cram D.S.: An ELISA for antibodies to recombinant glutamic acid decarboxylase in IDDM. Diabetes 41: 1182-1187, 1992.
    • (1992) Diabetes , vol.41 , pp. 1182-1187
    • Deaizpurua, H.J.1    Harrison, L.C.2    Cram, D.S.3
  • 58
    • 0029000791 scopus 로고
    • Disease sensitivity and specificity of 52 assays for glutamic acid decarboxylase antibodies. the second international GADAb workshop
    • Schmidli R.S., Colman P.G., Bonifacio E. and Participating Laboratories: Disease sensitivity and specificity of 52 assays for glutamic acid decarboxylase antibodies. The second international GADAb workshop. Diabetes 44: 636-640, 1995.
    • (1995) Diabetes , vol.44 , pp. 636-640
    • Schmidli, R.S.1    Colman, P.G.2    Bonifacio, E.3
  • 59
    • 0025141413 scopus 로고
    • Quantitative islet cell antibody measurement assists in the prediction of insulin-dependent diabetes
    • Bonifacio E., Bingley P.J. Shattock M., Dean B.M., Dunger D., Gale E.A.M., Bottazzo G.F.: Quantitative islet cell antibody measurement assists in the prediction of insulin-dependent diabetes. Lancet 335: 147-149, 1990.
    • (1990) Lancet , vol.335 , pp. 147-149
    • Bonifacio, E.1    Shattock M, B.P.J.2    Dean, B.M.3    Dunger, D.4    Gale, E.A.M.5    Bottazzo, G.F.6
  • 61
    • 0025003308 scopus 로고
    • Precision of the islet-cell antibody assav depends on the pancreas
    • Landin-Olsson M.: Precision of the islet-cell antibody assav depends on the pancreas. J. Clin. Lab. Annal. 4: 289-294, 1990.
    • (1990) J. Clin. Lab. Annal. , vol.4 , pp. 289-294
    • Landin-Olsson, M.1
  • 63
    • 0029995958 scopus 로고    scopus 로고
    • Prediction of Type I diabetes in first degree relatives using a combination of insulin, glutamic acid decarboxylase and ICA512 autoantibodies
    • Verge C.F., Gianani R., Kawasaki E., Yu L., Pietroapolo M., Jackson R.A., Chase H.P., Eisenbarth G.S.: Prediction of Type I diabetes in first degree relatives using a combination of insulin, glutamic acid decarboxylase and ICA512 autoantibodies. Diabetes 45: 926-933, 1996.
    • (1996) Diabetes , vol.45 , pp. 926-933
    • Verge, C.F.1    Gianani, R.2    Kawasaki, E.3    Yu, L.4    Pietroapolo, M.5    Jackson, R.A.6    Chase, H.P.7    Eisenbarth, G.S.8
  • 65
    • 0025966519 scopus 로고
    • Major cross-country differences in risk of dying for people with IDDM
    • Diabetes Epidemiology Research Intl Mortality Study Group: Major cross-country differences in risk of dying for people with IDDM. Diabetes Care 14: 49-60, 1991.
    • (1991) Diabetes Care , vol.14 , pp. 49-60
  • 68
    • 0021249781 scopus 로고
    • Differences in nsk of insulin-dependent diabetes in offspring of diabetic mothers and diabetic fathers
    • Warram H.H., Krolewski A.S., Gottlieb M.S., Kahn C.R.: Differences in nsk of insulin-dependent diabetes in offspring of diabetic mothers and diabetic fathers. N. Engl. J. Med 311: 149-152, 1984.
    • (1984) N. Engl. J. Med , vol.311 , pp. 149-152
    • Warram, H.H.1    Krolewski, A.S.2    Gottlieb, M.S.3    Kahn, C.R.4
  • 69
    • 0023550313 scopus 로고
    • Age-correlated empirical genetic risk estimates for first degree relatives of IDDM patients
    • Tillil H., Kobberling J.: Age-correlated empirical genetic risk estimates for first degree relatives of IDDM patients. Diabetes 36: 93-99, 1987.
    • (1987) Diabetes , vol.36 , pp. 93-99
    • Tillil, H.1    Kobberling, J.2
  • 70
    • 0027165390 scopus 로고
    • Decreased risk of Type I diabetes in offspring of mothers who acquire diabetes durins adrenarchy
    • Bleich D., Polak M., Eisenbarth G.S., Jackson R.A.: Decreased risk of Type I diabetes in offspring of mothers who acquire diabetes durins adrenarchy. Diabetes 42: 1433-1439, 1993.
    • (1993) Diabetes , vol.42 , pp. 1433-1439
    • Bleich, D.1    Polak, M.2    Eisenbarth, G.S.3    Jackson, R.A.4
  • 71
    • 0028882604 scopus 로고
    • Sexual dimorphism in transmission of expression of islet autoantibodies to offspring
    • Yu L., Chase H.P., Falorni A., Rewers M., Lernmark A., Eisenbarth G.S.: Sexual dimorphism in transmission of expression of islet autoantibodies to offspring. Diabetologia 38: 1353-1357, 1995.
    • (1995) Diabetologia , vol.38 , pp. 1353-1357
    • Yu, L.1    Chase, H.P.2    Falorni, A.3    Rewers, M.4    Lernmark, A.5    Eisenbarth, G.S.6
  • 72
    • 0028911293 scopus 로고
    • High diagnostic sensitivity of glutamate decarboxylase autoantibodies in insulin-dependent diabetes mellitus with clinical onset between age 20 and 40 years
    • Vandewalle C.L., Falorni A., Svanholm S., Lernmark A., Pipeleers D.G., Gorus F.K. and the Belgian Diabetes Registry: High diagnostic sensitivity of glutamate decarboxylase autoantibodies in insulin-dependent diabetes mellitus with clinical onset between age 20 and 40 years. J. Clin. Endocrinol. Metab. 80: 846-851, 1995.
    • (1995) J. Clin. Endocrinol. Metab. , vol.80 , pp. 846-851
    • Vandewalle, C.L.1    Falorni, A.2    Svanholm, S.3    Lernmark, A.4    Pipeleers, D.G.5    Gorus, F.K.6
  • 73
    • 0025131118 scopus 로고
    • A unified hypothesis for the complex genetics of HLA associations with IDDM
    • Nepom G.T.: A unified hypothesis for the complex genetics of HLA associations with IDDM. Diabetes 39: 1153-1157, 1990.
    • (1990) Diabetes , vol.39 , pp. 1153-1157
    • Nepom, G.T.1
  • 74
    • 0025331496 scopus 로고
    • Analysis of HLA-DQ genotypes and susceptibility in insulin-dependent diabetes mellitus
    • Baisch J.M., Week T., Giles, R., Hoover M., Stastny P., Capra D.: Analysis of HLA-DQ genotypes and susceptibility in insulin-dependent diabetes mellitus. N. Engl. J. Med. 322: 1836-1841, 1990.
    • (1990) N. Engl. J. Med. , vol.322 , pp. 1836-1841
    • Baisch, J.M.1    Week, T.2    Giles, R.3    Hoover, M.4    Stastny, P.5    Capra, D.6
  • 75
    • 0026500805 scopus 로고
    • HLA and insulin-dependent diabetes
    • Sheehy M.J.: HLA and insulin-dependent diabetes. Diabetes 41: 123-129, 1992.
    • (1992) Diabetes , vol.41 , pp. 123-129
    • Sheehy, M.J.1
  • 76
    • 0025896881 scopus 로고
    • Specific association of HLA-DR4 with incresased prevalence and level of insulin autoantibodies in first degree relatives of patients with Type I diabetes
    • Ziegler R., Alper CA., Awdeh Z.L., Castano L., Brink S.J., Soeldner J.S., Jackson R.A., Eisenbarth G.S.: Specific association of HLA-DR4 with incresased prevalence and level of insulin autoantibodies in first degree relatives of patients with Type I diabetes. Diabetes 40: 709-714, 1991.
    • (1991) Diabetes , vol.40 , pp. 709-714
    • Ziegler, R.1    Alper, C.A.2    Awdeh, Z.L.3    Castano, L.4    Brink, S.J.5    Soeldner, J.S.6    Jackson, R.A.7    Eisenbarth, G.S.8
  • 77
    • 0025899032 scopus 로고
    • HLA-associated insulin autoantibody formation in newly diagnosed Type I diabetic patients
    • Ziegler A.G., Standl E., Albert E., Mehnert H.: HLA-associated insulin autoantibody formation in newly diagnosed Type I diabetic patients. Diabetes 40: 1146-1149, 1991.
    • (1991) Diabetes , vol.40 , pp. 1146-1149
    • Ziegler, A.G.1    Standl, E.2    Albert, E.3    Mehnert, H.4
  • 78
    • 0027490736 scopus 로고
    • Insulin autoantibodies and high titre islet cell antibodies are preferentially associated with the HLA DQA*0301-DQB 1*0302 haplotype at clinical onset of Type I (insulin-dependent) diabetes mellitus before age 10 years, but not at onset between age 10 and 40 years
    • Vandewalle C.L., Decraene T., Schuit F.C., De Leeuw I.H., Pipeleers D.G., Gorus F.K.: Insulin autoantibodies and high titre islet cell antibodies are preferentially associated with the HLA DQA*0301-DQB 1*0302 haplotype at clinical onset of Type I (insulin-dependent) diabetes mellitus before age 10 years, but not at onset between age 10 and 40 years. Diabetologia 36: 1155-1162, 1993.
    • (1993) Diabetologia , vol.36 , pp. 1155-1162
    • Vandewalle, C.L.1    Decraene, T.2    Schuit, F.C.3    De Leeuw, I.H.4    Pipeleers, D.G.5    Gorus, F.K.6
  • 79
    • 0028325393 scopus 로고
    • Influence of age on the associations among insulin autoantibodies, islet cell antibodies, and HLA DQA1 *0301-DQB 1*0302 in siblings of patients with Type I (insulin-dependent) diabetes mellitus
    • Gorus F.K., Vandewalle C.L., Dorchy H., Crombrugge P.V., Schuit F.C., Pipeleers D.G.: Influence of age on the associations among insulin autoantibodies, islet cell antibodies, and HLA DQA1 *0301-DQB 1*0302 in siblings of patients with Type I (insulin-dependent) diabetes mellitus. J. Clin. Endocrinol. Metab. 1172-1 178, 1994.
    • (1994) J. Clin. Endocrinol. Metab. , pp. 1172-1178
    • Gorus, F.K.1    Vandewalle, C.L.2    Dorchy, H.3    Crombrugge, P.V.4    Schuit, F.C.5    Pipeleers, D.G.6
  • 80
    • 0028239150 scopus 로고
    • Two subsets of HLA-DQA1 alleles mark phenotypic variation in levels of insulin autoantibodies in first degree relatives at risk for insulin-dependent diabetes
    • Pugliese A., Bugawan T., Moromisato R., Awdeh Z.L., Alper C.A., Jackson R.A., Erlich H.A., Eisenbarth G.S.: Two subsets of HLA-DQA1 alleles mark phenotypic variation in levels of insulin autoantibodies in first degree relatives at risk for insulin-dependent diabetes. J. Clin. Invest. 93: 2447-2452, 1994.
    • (1994) J. Clin. Invest. , vol.93 , pp. 2447-2452
    • Pugliese, A.1    Bugawan, T.2    Moromisato, R.3    Awdeh, Z.L.4    Alper, C.A.5    Jackson, R.A.6    Erlich, H.A.7    Eisenbarth, G.S.8
  • 81
    • 0023252262 scopus 로고
    • HLA-DQB gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus
    • Todd J.A., Bell J.I., McDevitt H.O.: HLA-DQB gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus. Nature 329: 599-604, 1987.
    • (1987) Nature , vol.329 , pp. 599-604
    • Todd, J.A.1    Bell, J.I.2    McDevitt, H.O.3
  • 83
    • 0025331496 scopus 로고
    • Analysis of HLA-DQ genotypes and susceptibility in insulin-dependent diabetes mellitus
    • Baisch J.M., Weeks T., Giles R., Hoover M., Stastny P., Capra J.D.: Analysis of HLA-DQ genotypes and susceptibility in insulin-dependent diabetes mellitus. N. Engl. J. Med 322: 1836-1841, 1990.
    • (1990) N. Engl. J. Med , vol.322 , pp. 1836-1841
    • Baisch, J.M.1    Weeks, T.2    Giles, R.3    Hoover, M.4    Stastny, P.5    Capra, J.D.6
  • 85
    • 0027480065 scopus 로고
    • Insulin prophylaxis in individuals at high risk of Type I diabetes
    • Keller R.J., Eisenbarth G.S., Jackson R.A.: Insulin prophylaxis in individuals at high risk of Type I diabetes. Lancei 341: 927-928, 1993.
    • (1993) Lancei , vol.341 , pp. 927-928
    • Keller, R.J.1    Eisenbarth, G.S.2    Jackson, R.A.3
  • 86
    • 0026574043 scopus 로고
    • Insulin autoimmunity: The rate limiting factor in pre-Type I diabetes
    • Eisenbarth G.S., Jackson R.A., Pugliese A.: Insulin autoimmunity: the rate limiting factor in pre-Type I diabetes. J. Autoimmunitry 5 (Suppl A): 241-246, 1992.
    • (1992) J. Autoimmunitry , vol.5 , Issue.SUPPL. A , pp. 241-246
    • Eisenbarth, G.S.1    Jackson, R.A.2    Pugliese, A.3
  • 87
    • 0024459097 scopus 로고
    • Life table analysis of progression to diabetes of anti-insulin autoantibody positive relatives of individuals with Type I diabetes
    • Ziegler A.G., Ziegler R., Vardi P., Jackson R.A., Soeldner J.S., Eisenbarth G.S.: Life table analysis of progression to diabetes of anti-insulin autoantibody positive relatives of individuals with Type I diabetes. Diabetes 38: 1320-1325. 1989.
    • (1989) Diabetes , vol.38 , pp. 1320-1325
    • Ziegler, A.G.1    Ziegler, R.2    Vardi, P.3    Jackson, R.A.4    Soeldner, J.S.5    Eisenbarth, G.S.6
  • 88
    • 0024341933 scopus 로고
    • Relationship of insulin autoantibodies to presentation and early course of IDDM in Children
    • Sochett E., Daneman D.: Relationship of insulin autoantibodies to presentation and early course of IDDM in Children. Diabetes Care 12: 517-523, 1989.
    • (1989) Diabetes Care , vol.12 , pp. 517-523
    • Sochett, E.1    Daneman, D.2
  • 89
    • 0021857808 scopus 로고
    • Correlates of insulin antibodies in newly diagnosed children with insulin-dependent diabetes before insulin therapy
    • Arslanian S.L., Becker D.J., Rabin B., Atchison R., Eberhardt M., Cavender D., Dorman J., Drash A.L.: Correlates of insulin antibodies in newly diagnosed children with insulin-dependent diabetes before insulin therapy. Diabetes 34: 926-930, 1985.
    • (1985) Diabetes , vol.34 , pp. 926-930
    • Arslanian, S.L.1    Becker, D.J.2    Rabin, B.3    Atchison, R.4    Eberhardt, M.5    Cavender, D.6    Dorman, J.7    Drash, A.L.8
  • 90
    • 0023780153 scopus 로고
    • Insulin autoantibodies are associated with islet cell antibodies: Their relation to insulin antibodies and B cell function in diabetic children
    • Ludvigsson J., Binder C., Mandrup-Poulsen T.: Insulin autoantibodies are associated with islet cell antibodies: their relation to insulin antibodies and B cell function in diabetic children. Diabetologia 31: 647-651, 1988.
    • (1988) Diabetologia , vol.31 , pp. 647-651
    • Ludvigsson, J.1    Binder, C.2    Mandrup-Poulsen, T.3
  • 92
    • 0027200763 scopus 로고
    • Susceptibility to insulin dependent diabetes mellitus maps to a 4.1 kb segment of DNA spanning the insulin gene and associated VNTR
    • Lucassen A.M., Julier C., Beressi J., Boitard C., Froguel P., Lathrop M., Bell J.I.: Susceptibility to insulin dependent diabetes mellitus maps to a 4.1 kb segment of DNA spanning the insulin gene and associated VNTR. Nature Genet. 4: 305-310, 1993.
    • (1993) Nature Genet. , vol.4 , pp. 305-310
    • Lucassen, A.M.1    Julier, C.2    Beressi, J.3    Boitard, C.4    Froguel, P.5    Lathrop, M.6    Bell, J.I.7
  • 93
    • 0027333071 scopus 로고
    • Localization of a type 1 diabetes susceptibility locus to the variable tandem repeat region fianking the insulin gene
    • Owerbach D., Gabbay K.H.: Localization of a type 1 diabetes susceptibility locus to the variable tandem repeat region fianking the insulin gene. Diabetes 42: 1708-1714, 1993.
    • (1993) Diabetes , vol.42 , pp. 1708-1714
    • Owerbach, D.1    Gabbay, K.H.2
  • 94
    • 0025837184 scopus 로고
    • Suppression of diabetes in nonobese diabetic mice by oral administration of porcine insulin
    • Zhang J.Z., Davidson L., Eisenbarth G.S , Weiner H.L.: Suppression of diabetes in nonobese diabetic mice by oral administration of porcine insulin. Proc. Natl. Acad. Sci. (USA) 88: 10252-10256, 1991.
    • (1991) Proc. Natl. Acad. Sci. (USA) , vol.88 , pp. 10252-10256
    • Zhang, J.Z.1    Davidson, L.2    Eisenbarth, G.S.3    Weiner, H.L.4
  • 95
    • 0013690606 scopus 로고
    • Oral insulin induces CD4* regulatory cells that protect NOD mice from adoptive transfer of diabetes
    • Abstract
    • Bergerot I., Fabien N., Maguer V., Thivolet C.: Oral insulin induces CD4* regulatory cells that protect NOD mice from adoptive transfer of diabetes. J. Imnumol. 1994 (Abstract).
    • (1994) J. Imnumol.
    • Bergerot, I.1    Fabien, N.2    Maguer, V.3    Thivolet, C.4
  • 96
    • 0027257390 scopus 로고
    • Perspectives in Diabetes: The 12th international immunology and diabetes workshop
    • Maclaren N., Lafferty K.: Perspectives in Diabetes: The 12th international immunology and diabetes workshop. Diabetes 42: 1099-1104, 19937
    • (1993) Diabetes , vol.42 , pp. 1099-1104
    • Maclaren, N.1    Lafferty, K.2
  • 97
    • 0028861576 scopus 로고
    • Insulin immunization of nonobese diabetic mice induces a protective insulitis characterized by diminished intraislet interferongamma transcription
    • Muir A., Peck A., Clare-Salzler M., Yao-Hua S., Cornelius J., Luchetta R., Krischer J., Maclaren N.: Insulin immunization of nonobese diabetic mice induces a protective insulitis characterized by diminished intraislet interferongamma transcription. J. Clin. Invest. 95: 628-634, 1995.
    • (1995) J. Clin. Invest. , vol.95 , pp. 628-634
    • Muir, A.1    Peck, A.2    Clare-Salzler, M.3    Yao-Hua, S.4    Cornelius, J.5    Luchetta, R.6    Krischer, J.7    Maclaren, N.8
  • 98
    • 10244267266 scopus 로고
    • Protection of NOD mice from diabetes by intranasal or subcutaneous administration of insulin peptide B:9-23
    • In Press
    • Daniel D., Wegmann D.R.: Protection of NOD mice from diabetes by intranasal or subcutaneous administration of insulin peptide B:9-23. Proc. Natl. Acad. Sci. 1995(In Press).
    • (1995) Proc. Natl. Acad. Sci.
    • Daniel, D.1    Wegmann, D.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.