-
1
-
-
0000607018
-
Synthesis of deoxyribonucleic acid in normal and irradiated cells and its relation to chromosome breakage
-
Howard A, Pelc SR: Synthesis of deoxyribonucleic acid in normal and irradiated cells and its relation to chromosome breakage. Heredity (Suppl) 6:261-273, 1953.
-
(1953)
Heredity (Suppl)
, vol.6
, pp. 261-273
-
-
Howard, A.1
Pelc, S.R.2
-
2
-
-
0002309215
-
Variations in several responses of Hela cells to X-irradiation during the division cycle
-
Terasima T, Tolmach LJ: Variations in several responses of Hela cells to X-irradiation during the division cycle. Biophys J 3:11-33, 1963.
-
(1963)
Biophys J
, vol.3
, pp. 11-33
-
-
Terasima, T.1
Tolmach, L.J.2
-
3
-
-
0009697127
-
Variations in X-ray response during the division cycle of partially synchronized Chinese hamster cells in culture
-
Sinclair W, Morton R: Variations in X-ray response during the division cycle of partially synchronized Chinese hamster cells in culture. Nature 199:1158-1160, 1963.
-
(1963)
Nature
, vol.199
, pp. 1158-1160
-
-
Sinclair, W.1
Morton, R.2
-
4
-
-
0016729499
-
Hydroxyurea
-
Timson J: Hydroxyurea. Mutat Res 32:115-132, 1975.
-
(1975)
Mutat Res
, vol.32
, pp. 115-132
-
-
Timson, J.1
-
5
-
-
0027655796
-
The clinical rationale for S-phase radiosensitization in human tumors
-
McGinn CJ, Kinsella TK: The clinical rationale for S-phase radiosensitization in human tumors. Curr Probl Cancer 17:273-321, 1993.
-
(1993)
Curr Probl Cancer
, vol.17
, pp. 273-321
-
-
McGinn, C.J.1
Kinsella, T.K.2
-
6
-
-
20244364373
-
Hyperfractionation versus conventional fractionation in oropharyngeal carcinoma: Final analysis of a randomized trial of the EORTC cooperative group of radiotherapy
-
Horiot JC, Le Fur R, N'Guyen T, Chenal C, Schraub S, Alfonsi S, Gardani G, van den Boegaert W, Danczak S, Bolla M, van Glabbeke M, De Pauw M: Hyperfractionation versus conventional fractionation in oropharyngeal carcinoma: Final analysis of a randomized trial of the EORTC cooperative group of radiotherapy. Radiother Oncol 25:231-241, 1992.
-
(1992)
Radiother Oncol
, vol.25
, pp. 231-241
-
-
Horiot, J.C.1
Le Fur, R.2
N'Guyen, T.3
Chenal, C.4
Schraub, S.5
Alfonsi, S.6
Gardani, G.7
Van Den Boegaert, W.8
Danczak, S.9
Bolla, M.10
Van Glabbeke, M.11
De Pauw, M.12
-
7
-
-
0029166905
-
In vivo cell kinetics in head and neck squamous cell carcinomas predicts local control and helps guide radiotherapy regimen
-
Corvo R, Giaretti W, Sanguineti G, et al.: In vivo cell kinetics in head and neck squamous cell carcinomas predicts local control and helps guide radiotherapy regimen. J Clin Oncol 13:1843-1850, 1995.
-
(1995)
J Clin Oncol
, vol.13
, pp. 1843-1850
-
-
Corvo, R.1
Giaretti, W.2
Sanguineti, G.3
-
8
-
-
0029102298
-
pot in cancer of the uterine cervix: Correlation between two laboratories and preliminary clinical results
-
pot in cancer of the uterine cervix: Correlation between two laboratories and preliminary clinical results. Int J Radiat Oncol Biol Phys 32:1319-1329, 1995.
-
(1995)
Int J Radiat Oncol Biol Phys
, vol.32
, pp. 1319-1329
-
-
Tsang, R.1
Fyles, A.2
Kirkbridge, P.3
Levin, W.4
Manchul, L.5
Milosevic, M.6
Rawlings, G.7
Banerjee, D.8
Pintilie, M.9
Wilson, G.10
-
9
-
-
0026703325
-
Creative blocks: Cell-cycle checkpoints and feedback controls
-
Murray AW: Creative blocks: Cell-cycle checkpoints and feedback controls. Nature 359:599-604, 1992.
-
(1992)
Nature
, vol.359
, pp. 599-604
-
-
Murray, A.W.1
-
10
-
-
0028307190
-
The molecular basis for cell cycle delays following ionizing radiation: A review
-
Maity A, McKenna WG, Muschel RJ: The molecular basis for cell cycle delays following ionizing radiation: A review. Radiother Oncol 31:1-13, 1994.
-
(1994)
Radiother Oncol
, vol.31
, pp. 1-13
-
-
Maity, A.1
McKenna, W.G.2
Muschel, R.J.3
-
11
-
-
0024425887
-
Checkpoints: Controls that ensure the order of cell cycle events
-
Hartwell LH, Weinert TA: Checkpoints: Controls that ensure the order of cell cycle events. Science 246:629-634, 1989.
-
(1989)
Science
, vol.246
, pp. 629-634
-
-
Hartwell, L.H.1
Weinert, T.A.2
-
12
-
-
0001221768
-
Action of radiation on mammalian cells. IV. Reversible mitotic lag in the S3 Hela cell produced by low doses of X-rays
-
Yamada M, Puck TT: Action of radiation on mammalian cells. IV. Reversible mitotic lag in the S3 Hela cell produced by low doses of X-rays. Proc Natl Acad Sci USA 47:1181-1191, 1961.
-
(1961)
Proc Natl Acad Sci USA
, vol.47
, pp. 1181-1191
-
-
Yamada, M.1
Puck, T.T.2
-
13
-
-
0026318356
-
Participation of p53 protein in the cellular response to DNA damage
-
Kastan MB, Onyekwere O, Sidransky D, Vogelstein B, Craig RW: Participation of p53 protein in the cellular response to DNA damage. Cancer Res 51:6304-6311, 1991.
-
(1991)
Cancer Res
, vol.51
, pp. 6304-6311
-
-
Kastan, M.B.1
Onyekwere, O.2
Sidransky, D.3
Vogelstein, B.4
Craig, R.W.5
-
14
-
-
0016652409
-
X-ray-induced inhibition of DNA synthesis in Chinese hamster ovary, human HeLa, and mouse L cells
-
Painter RB, Young BR: X-ray-induced inhibition of DNA synthesis in Chinese hamster ovary, human HeLa, and mouse L cells. Radiat Res 64:648-656, 1975.
-
(1975)
Radiat Res
, vol.64
, pp. 648-656
-
-
Painter, R.B.1
Young, B.R.2
-
15
-
-
0028568315
-
Cell cycle control and cancer
-
Hartwell L, Kastan M: Cell cycle control and cancer. Science 266:1821-1828, 1994.
-
(1994)
Science
, vol.266
, pp. 1821-1828
-
-
Hartwell, L.1
Kastan, M.2
-
16
-
-
0028587230
-
Radiation checkpoints in model systems
-
Carr A: Radiation checkpoints in model systems. Int J Radiat Biol 66(Suppl 6):S133-139, 1994.
-
(1994)
Int J Radiat Biol
, vol.66
, Issue.6 SUPPL.
-
-
Carr, A.1
-
17
-
-
0029057336
-
A single ataxia telangiectasia gene with a product similar to PI-3 kinase
-
Savitsky K, Bar-Shira A, Gilad S, et al.: A single ataxia telangiectasia gene with a product similar to PI-3 kinase. Science 268:1749-1753, 1995.
-
(1995)
Science
, vol.268
, pp. 1749-1753
-
-
Savitsky, K.1
Bar-Shira, A.2
Gilad, S.3
-
18
-
-
0028931265
-
Principles of CDK regulation
-
Morgan DO: Principles of CDK regulation. Nature 374:131-134, 1995.
-
(1995)
Nature
, vol.374
, pp. 131-134
-
-
Morgan, D.O.1
-
19
-
-
0028173667
-
Acceleration of the G1/S phase transition by expression of cyclins D1 and e with an inducible system
-
Reznitsky D, Gossen M, Bujard H, Reed S: Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system. Mol Cell Biol 14:1669-1679, 1994.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 1669-1679
-
-
Reznitsky, D.1
Gossen, M.2
Bujard, H.3
Reed, S.4
-
20
-
-
0027193034
-
Cyclin-dependent regulation of G1 in mammalian fibroblasts
-
Ohtsubo M, Roberts JM: Cyclin-dependent regulation of G1 in mammalian fibroblasts. Science 259:1908-1912, 1993.
-
(1993)
Science
, vol.259
, pp. 1908-1912
-
-
Ohtsubo, M.1
Roberts, J.M.2
-
21
-
-
0003418645
-
A restriction point for control of normal cell proliferation
-
Pardee A: A restriction point for control of normal cell proliferation. Proc Natl Acad Sci USA 71:1286-1290, 1974.
-
(1974)
Proc Natl Acad Sci USA
, vol.71
, pp. 1286-1290
-
-
Pardee, A.1
-
22
-
-
0028967830
-
Cyclin D1 oncoprotein aberrantly accumulates in malignancies of diverse histogenesis
-
Bartkova J, Lukas J, Strauss M, Bartek J: Cyclin D1 oncoprotein aberrantly accumulates in malignancies of diverse histogenesis. Oncogene 10:775-778, 1995.
-
(1995)
Oncogene
, vol.10
, pp. 775-778
-
-
Bartkova, J.1
Lukas, J.2
Strauss, M.3
Bartek, J.4
-
23
-
-
0027273790
-
Amplification of cyclin genes in colorectal carcinomas
-
Leach F, Elledge S, Sherr C, Willson J, Markowitz S, Kinzler K, Vogelstein B: Amplification of cyclin genes in colorectal carcinomas. Cancer Res 53:1986-1989, 1993.
-
(1993)
Cancer Res
, vol.53
, pp. 1986-1989
-
-
Leach, F.1
Elledge, S.2
Sherr, C.3
Willson, J.4
Markowitz, S.5
Kinzler, K.6
Vogelstein, B.7
-
24
-
-
0028978274
-
INK4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanoma
-
INK4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanoma. Science 269:1281-1284, 1995.
-
(1995)
Science
, vol.269
, pp. 1281-1284
-
-
Wolfel, T.1
Hauer, M.2
Schneider, J.3
Serrano, M.4
Wolfel, C.5
Klehmann-Heib, E.6
De Plaen, E.7
Hankeln, T.8
Zum Buschenfelde, K.9
Beach, D.10
-
25
-
-
0029111934
-
Cyclin D1 provides a link between development and oncogenesis in the retina and breast
-
Sicinski P, Donaher J, Parker S, Li T, Fazeli A, Gardner H, Haslam S, Bronson R, Elledge S, Weinberg R: Cyclin D1 provides a link between development and oncogenesis in the retina and breast. Cell 82:621-630, 1995.
-
(1995)
Cell
, vol.82
, pp. 621-630
-
-
Sicinski, P.1
Donaher, J.2
Parker, S.3
Li, T.4
Fazeli, A.5
Gardner, H.6
Haslam, S.7
Bronson, R.8
Elledge, S.9
Weinberg, R.10
-
26
-
-
0027374766
-
TGF beta inhibition of Cdk4 synthesis is linked to cell cycle arrest
-
Ewen M, Sluss H, Whitehouse L, Livingston D: TGF beta inhibition of Cdk4 synthesis is linked to cell cycle arrest. Cell 74:1009-1020, 1993.
-
(1993)
Cell
, vol.74
, pp. 1009-1020
-
-
Ewen, M.1
Sluss, H.2
Whitehouse, L.3
Livingston, D.4
-
27
-
-
0029670837
-
p21 disrupts the interactions between cdk2 and E2F
-
Shiyanov P, Bagchi S, Adami G, Kokontis J, Hay N, Arroyo M, Morozov A, Raychaudhuri P: p21 disrupts the interactions between cdk2 and E2F. Mol Cell Biol 16:737-744, 1996.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 737-744
-
-
Shiyanov, P.1
Bagchi, S.2
Adami, G.3
Kokontis, J.4
Hay, N.5
Arroyo, M.6
Morozov, A.7
Raychaudhuri, P.8
-
28
-
-
0027496935
-
The p21 cdk interacting protein cip1 is a potent inhibitor of G1 cyclin dependent kinases
-
Harper J, Adami G, Wei N, Keyomarsi K, Elledge S: The p21 cdk interacting protein cip1 is a potent inhibitor of G1 cyclin dependent kinases. Cell 75:805-816, 1993.
-
(1993)
Cell
, vol.75
, pp. 805-816
-
-
Harper, J.1
Adami, G.2
Wei, N.3
Keyomarsi, K.4
Elledge, S.5
-
29
-
-
0027359827
-
WAF1, a potential mediator of p53 tumor suppression
-
El-Deiry W, Tokino T, Velculescu VE, Levy DB, Parsons R, Trent JM, Lin D, Mercer EW, Kinzler KW, Vogelstein B: WAF1, a potential mediator of p53 tumor suppression. Cell 75:817-825, 1993.
-
(1993)
Cell
, vol.75
, pp. 817-825
-
-
El-Deiry, W.1
Tokino, T.2
Velculescu, V.E.3
Levy, D.B.4
Parsons, R.5
Trent, J.M.6
Lin, D.7
Mercer, E.W.8
Kinzler, K.W.9
Vogelstein, B.10
-
30
-
-
0029134016
-
Role of cyclin dependent kinase inhibitors in the development of cancer
-
Hirami T, Koeffler P: Role of cyclin dependent kinase inhibitors in the development of cancer. Blood 86:841-854, 1995.
-
(1995)
Blood
, vol.86
, pp. 841-854
-
-
Hirami, T.1
Koeffler, P.2
-
31
-
-
0027717617
-
p21 is a universal inhibitor of cyclin kinases
-
Xiong Y, Hannon G, Zhang H, Casso D, Kobayashi R, Beach D: p21 is a universal inhibitor of cyclin kinases. Nature 366:701-704, 1993.
-
(1993)
Nature
, vol.366
, pp. 701-704
-
-
Xiong, Y.1
Hannon, G.2
Zhang, H.3
Casso, D.4
Kobayashi, R.5
Beach, D.6
-
32
-
-
0026849821
-
Definition of a consensus binding site for p53
-
El-Deiry WS, Kern SE, Pietenpol JA, Kinzler KW, Vogelstein B: Definition of a consensus binding site for p53. Nat Genet 1:45-49, 1992.
-
(1992)
Nat Genet
, vol.1
, pp. 45-49
-
-
El-Deiry, W.S.1
Kern, S.E.2
Pietenpol, J.A.3
Kinzler, K.W.4
Vogelstein, B.5
-
33
-
-
0027731971
-
Inhibition of CDK2 activity in vivo by an associated 20K regulatory sub-unit
-
Gu Y, Turck CW, Morgan DO: Inhibition of CDK2 activity in vivo by an associated 20K regulatory sub-unit. Nature 366:707-710, 1993.
-
(1993)
Nature
, vol.366
, pp. 707-710
-
-
Gu, Y.1
Turck, C.W.2
Morgan, D.O.3
-
34
-
-
0028978183
-
Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control
-
Deng C, Zhang P, Harper JW, Harper JW, Elledge SJ, Leder P: Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control. Cell 82:675-684, 1995.
-
(1995)
Cell
, vol.82
, pp. 675-684
-
-
Deng, C.1
Zhang, P.2
Harper, J.W.3
Harper, J.W.4
Elledge, S.J.5
Leder, P.6
-
35
-
-
0029097759
-
Radiation-induced cell cycle arrest compromised by p21 deficiency
-
Brugarolas J, Chandrasekaran C, Gordon JI, Beach D, Jacks T, Hannon GJ: Radiation-induced cell cycle arrest compromised by p21 deficiency. Nature 377:552-557, 1995.
-
(1995)
Nature
, vol.377
, pp. 552-557
-
-
Brugarolas, J.1
Chandrasekaran, C.2
Gordon, J.I.3
Beach, D.4
Jacks, T.5
Hannon, G.J.6
-
36
-
-
0028204160
-
DNA strand breaks: The DNA template alterations that trigger p53-dependent DNA damage response pathways
-
Nelson WG, Kastan MB: DNA strand breaks: The DNA template alterations that trigger p53-dependent DNA damage response pathways. Mol Cell Biol 14:1815-1823, 1994.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 1815-1823
-
-
Nelson, W.G.1
Kastan, M.B.2
-
37
-
-
0029038135
-
Apoptosis, cancer and the p53 tumour suppressor gene
-
Lee J, Bernstein A: Apoptosis, cancer and the p53 tumour suppressor gene. Cancer Met Rev 14:149-161, 1995.
-
(1995)
Cancer Met Rev
, vol.14
, pp. 149-161
-
-
Lee, J.1
Bernstein, A.2
-
38
-
-
0026656853
-
Wild-type p53 is a cell cycle checkpoint determinant following irradiation
-
Kuerbitz SJ, Plunkett BS, Walsh WV, Kastan MB: Wild-type p53 is a cell cycle checkpoint determinant following irradiation. Proc Natl Acad Sci USA 89:7491-7495, 1992.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 7491-7495
-
-
Kuerbitz, S.J.1
Plunkett, B.S.2
Walsh, W.V.3
Kastan, M.B.4
-
39
-
-
0028074603
-
Differential effects of the p21 CDK inhibitor on PCNA-dependent DNA replication and repair
-
Li R, Waga S, Hannon GJ, Beach D, Stillman B: Differential effects of the p21 CDK inhibitor on PCNA-dependent DNA replication and repair. Nature 371:534-537, 1994.
-
(1994)
Nature
, vol.371
, pp. 534-537
-
-
Li, R.1
Waga, S.2
Hannon, G.J.3
Beach, D.4
Stillman, B.5
-
41
-
-
0028569767
-
Interaction of the p53-regulated protein gadd45 with proliferating cell nuclear antigen
-
Smith ML, Chen I-T, Zhan Q, Bae I, Chen C-Y, Gilmer TM, Kastan MB, O'Connor PM, Fornace AJ Jr: Interaction of the p53-regulated protein gadd45 with proliferating cell nuclear antigen. Science 266:1376-1380, 1994.
-
(1994)
Science
, vol.266
, pp. 1376-1380
-
-
Smith, M.L.1
Chen, I.-T.2
Zhan, Q.3
Bae, I.4
Chen, C.-Y.5
Gilmer, T.M.6
Kastan, M.B.7
O'Connor, P.M.8
Fornace Jr., A.J.9
-
42
-
-
0029028353
-
Stimulation of E2F/DP1 transcriptional activity by MDM2 oncoprotein
-
Martin K, Trouche D, Hagemeier C, Sorenson T, La Thangue N, Kouzarides T: Stimulation of E2F/DP1 transcriptional activity by MDM2 oncoprotein. Nature 375:691-694, 1995.
-
(1995)
Nature
, vol.375
, pp. 691-694
-
-
Martin, K.1
Trouche, D.2
Hagemeier, C.3
Sorenson, T.4
La Thangue, N.5
Kouzarides, T.6
-
43
-
-
0029028354
-
Interaction between the retinoblastoma protein and the oncoprotein MDM2
-
Xiao Z, Chen J, Levine A, Modjtahedi N, Xing J, Sellers W, Livingston D: Interaction between the retinoblastoma protein and the oncoprotein MDM2. Nature 375:694-698, 1995.
-
(1995)
Nature
, vol.375
, pp. 694-698
-
-
Xiao, Z.1
Chen, J.2
Levine, A.3
Modjtahedi, N.4
Xing, J.5
Sellers, W.6
Livingston, D.7
-
44
-
-
0027944206
-
p53 status and the efficacy of cancer therapy in vivo
-
Lowe SW, Bodis S, McClatchey A, Remington L, Ruley HE, Fisher DE, Housman DE, Jacks T: p53 status and the efficacy of cancer therapy in vivo. Science 266:807-810, 1994.
-
(1994)
Science
, vol.266
, pp. 807-810
-
-
Lowe, S.W.1
Bodis, S.2
McClatchey, A.3
Remington, L.4
Ruley, H.E.5
Fisher, D.E.6
Housman, D.E.7
Jacks, T.8
-
45
-
-
0025894713
-
p53 mutations in human cancers
-
Hollstein M, Sidransky D, Vogelstein B, Harris CC: p53 mutations in human cancers. Science 253:49-53, 1991.
-
(1991)
Science
, vol.253
, pp. 49-53
-
-
Hollstein, M.1
Sidransky, D.2
Vogelstein, B.3
Harris, C.C.4
-
46
-
-
0028953478
-
Implications of the p53 tumor-suppressor gene in clinical oncology
-
Chang F, Syrjanen S, Syrjanen K: Implications of the p53 tumor-suppressor gene in clinical oncology. J Clin Oncol 13:1009-1022, 1995.
-
(1995)
J Clin Oncol
, vol.13
, pp. 1009-1022
-
-
Chang, F.1
Syrjanen, S.2
Syrjanen, K.3
-
47
-
-
0028025563
-
Apoptosis in cancer therapy: Crossing the threshold
-
Fisher DE: Apoptosis in cancer therapy: Crossing the threshold. Cell 78:539-542, 1994.
-
(1994)
Cell
, vol.78
, pp. 539-542
-
-
Fisher, D.E.1
-
48
-
-
0027285380
-
p53 mutations increase resistance to ionizing radiation
-
Lee J, Bernstein A: p53 mutations increase resistance to ionizing radiation. Proc Natl Acad Sci USA 90:5742-5746, 1993.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 5742-5746
-
-
Lee, J.1
Bernstein, A.2
-
49
-
-
0028318694
-
Mutant p53 increases radioresistance in rat embryo fibroblasts simultaneously transfected with HPV16-E7 and/or activated H-ras
-
Bristow RG, Jang A, Peacock J, Chung S, Benchimol S, Hill RP: Mutant p53 increases radioresistance in rat embryo fibroblasts simultaneously transfected with HPV16-E7 and/or activated H-ras. Oncogene 9:1527-1536, 1994.
-
(1994)
Oncogene
, vol.9
, pp. 1527-1536
-
-
Bristow, R.G.1
Jang, A.2
Peacock, J.3
Chung, S.4
Benchimol, S.5
Hill, R.P.6
-
50
-
-
0027931008
-
Cell cycle arrests and radiosensitivity of human tumor cell lines: Dependence on wild-type p53 for radiosensitivity
-
McIlwrath AJ, Vasey PA, Ross GM, Brown R: Cell cycle arrests and radiosensitivity of human tumor cell lines: Dependence on wild-type p53 for radiosensitivity. Cancer Res 54:3718-3722, 1994.
-
(1994)
Cancer Res
, vol.54
, pp. 3718-3722
-
-
McIlwrath, A.J.1
Vasey, P.A.2
Ross, G.M.3
Brown, R.4
-
51
-
-
0027421045
-
Role of the p53 tumor suppressor gene in cell cycle arrest and radiosensitivity of Burkitt's lymphoma cell lines
-
O'Connor PM, Jackman J, Jondle D, Bhatia K, Magrath I, Kohn KW: Role of the p53 tumor suppressor gene in cell cycle arrest and radiosensitivity of Burkitt's lymphoma cell lines. Cancer Res 53:4776-4780, 1993.
-
(1993)
Cancer Res
, vol.53
, pp. 4776-4780
-
-
O'Connor, P.M.1
Jackman, J.2
Jondle, D.3
Bhatia, K.4
Magrath, I.5
Kohn, K.W.6
-
52
-
-
0027893001
-
Loss of a p53-associated G1 checkpoint does not decrease cell survival following DNA damage
-
Slichenmyer WJ, Nelson WG, Slebos RJ, Kastan MB: Loss of a p53-associated G1 checkpoint does not decrease cell survival following DNA damage. Cancer Res 53:4164-4168, 1993.
-
(1993)
Cancer Res
, vol.53
, pp. 4164-4168
-
-
Slichenmyer, W.J.1
Nelson, W.G.2
Slebos, R.J.3
Kastan, M.B.4
-
53
-
-
0029023560
-
Dissection of the genetic programs of p53-mediated G1 growth arrest and apoptosis: Blocking p53-induced apoptosis unmasks G1 arrest
-
Guillouf C, Grana X, Selvakumaran M, De Luca A, Giordano A, Hoffman B, Liebermann DA: Dissection of the genetic programs of p53-mediated G1 growth arrest and apoptosis: Blocking p53-induced apoptosis unmasks G1 arrest. Blood 85:2691-2698, 1995.
-
(1995)
Blood
, vol.85
, pp. 2691-2698
-
-
Guillouf, C.1
Grana, X.2
Selvakumaran, M.3
De Luca, A.4
Giordano, A.5
Hoffman, B.6
Liebermann, D.A.7
-
54
-
-
0026388063
-
Apoptosis in irradiated murine tumors
-
Stephens LC, Ang KK, Schultheiss TE, Milas L, Meyn RE: Apoptosis in irradiated murine tumors. Radiat Res 127:308-316, 1991.
-
(1991)
Radiat Res
, vol.127
, pp. 308-316
-
-
Stephens, L.C.1
Ang, K.K.2
Schultheiss, T.E.3
Milas, L.4
Meyn, R.E.5
-
55
-
-
0028575336
-
Radiation-induced apoptosis in sensitive and resistant cells isolated from a mouse lymphoma
-
Story MD, Voehringer DW, Malone CG, Hobbs ML, Meyn RE: Radiation-induced apoptosis in sensitive and resistant cells isolated from a mouse lymphoma. Int J Radiat Biol 66:659-668, 1994.
-
(1994)
Int J Radiat Biol
, vol.66
, pp. 659-668
-
-
Story, M.D.1
Voehringer, D.W.2
Malone, C.G.3
Hobbs, M.L.4
Meyn, R.E.5
-
56
-
-
20644471948
-
-
Unpublished data
-
Rudoltz MS, Kao G, Bernhard EJ, Bakanauskas VJ, Muschel RJ, McKenna WG: Unpublished data.
-
-
-
Rudoltz, M.S.1
Kao, G.2
Bernhard, E.J.3
Bakanauskas, V.J.4
Muschel, R.J.5
McKenna, W.G.6
-
57
-
-
0028818126
-
Bcl-2 expression delays drug-induced apoptosis but does not increase clonogenic survival after drug treatment in HeLa cells
-
Yin DX, Schimke RT: Bcl-2 expression delays drug-induced apoptosis but does not increase clonogenic survival after drug treatment in HeLa cells. Cancer Res 55:4922-4928, 1995.
-
(1995)
Cancer Res
, vol.55
, pp. 4922-4928
-
-
Yin, D.X.1
Schimke, R.T.2
-
58
-
-
0024809865
-
Complex formation of human papillomavirus E7 proteins with the retinoblastoma tumor suppressor gene product
-
Munger K, Werness B, Dyson N, Phelps W, Harlow E, Howley P: Complex formation of human papillomavirus E7 proteins with the retinoblastoma tumor suppressor gene product. EMBO J 8:4099-4105, 1989.
-
(1989)
EMBO J
, vol.8
, pp. 4099-4105
-
-
Munger, K.1
Werness, B.2
Dyson, N.3
Phelps, W.4
Harlow, E.5
Howley, P.6
-
59
-
-
0025639158
-
The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53
-
Scheffner M, Werness B, Huibregtse J, Levine A, Howley P: The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53. Cell 63:1129-1136, 1990.
-
(1990)
Cell
, vol.63
, pp. 1129-1136
-
-
Scheffner, M.1
Werness, B.2
Huibregtse, J.3
Levine, A.4
Howley, P.5
-
60
-
-
0027938209
-
Cyclins and cancer. II: Cyclin D and CDK inhibitors come of age
-
Hunter T, Pines J: Cyclins and cancer. II: Cyclin D and CDK inhibitors come of age. Cell 79:573-582, 1994.
-
(1994)
Cell
, vol.79
, pp. 573-582
-
-
Hunter, T.1
Pines, J.2
-
61
-
-
0028100903
-
Germline p16 mutations in familial melanoma
-
Hussussian C, Struewing J, Goldstein A, Higgins P, Ally D, Sheahan M, Clark WJ, Tucker M, Dracopoli N: Germline p16 mutations in familial melanoma. Nat Genet 8:15-21, 1994.
-
(1994)
Nat Genet
, vol.8
, pp. 15-21
-
-
Hussussian, C.1
Struewing, J.2
Goldstein, A.3
Higgins, P.4
Ally, D.5
Sheahan, M.6
Clark, W.J.7
Tucker, M.8
Dracopoli, N.9
-
62
-
-
0029129816
-
Increased risk of pancreatic cancer in melanoma-prone kindreds with p16INK4 mutations
-
Goldstein A, Fraser M, Struewing J, et al.: Increased risk of pancreatic cancer in melanoma-prone kindreds with p16INK4 mutations. N Engl J Med 333:970-974, 1995.
-
(1995)
N Engl J Med
, vol.333
, pp. 970-974
-
-
Goldstein, A.1
Fraser, M.2
Struewing, J.3
-
63
-
-
0028798818
-
MTS-1 (CDKN2) tumor suppressor gene deletions are a frequent event in esophagus squamous cancer and pancreatic adenocarcinoma cell lines
-
Liu Q, Van Y, McClure M, Nakagawa H, Fujimura F, Rustgi A: MTS-1 (CDKN2) tumor suppressor gene deletions are a frequent event in esophagus squamous cancer and pancreatic adenocarcinoma cell lines. Oncogene 10:619-622, 1995.
-
(1995)
Oncogene
, vol.10
, pp. 619-622
-
-
Liu, Q.1
Van, Y.2
McClure, M.3
Nakagawa, H.4
Fujimura, F.5
Rustgi, A.6
-
64
-
-
0028963221
-
In vivo molecular therapy with p53 adenovirus for microscopic residual head and neck squamous carcinoma
-
Clayman GL, el-Naggar AK, Roth JA, Zhang WW, Goepfert H, Taylor DL, Liu TJ: In vivo molecular therapy with p53 adenovirus for microscopic residual head and neck squamous carcinoma. Cancer Res 55:1-6, 1995.
-
(1995)
Cancer Res
, vol.55
, pp. 1-6
-
-
Clayman, G.L.1
El-Naggar, A.K.2
Roth, J.A.3
Zhang, W.W.4
Goepfert, H.5
Taylor, D.L.6
Liu, T.J.7
-
65
-
-
0028069906
-
Growth suppression of human head and neck cancer cells by the introduction of a wild-type p53 gene via a recombinant adenovirus
-
Liu TJ, Zhang WW, Taylor DL, Roth JA, Goepfert H, Clayman GL: Growth suppression of human head and neck cancer cells by the introduction of a wild-type p53 gene via a recombinant adenovirus. Cancer Res 54:3662-3667, 1994.
-
(1994)
Cancer Res
, vol.54
, pp. 3662-3667
-
-
Liu, T.J.1
Zhang, W.W.2
Taylor, D.L.3
Roth, J.A.4
Goepfert, H.5
Clayman, G.L.6
-
66
-
-
0029017333
-
Apoptosis induction mediated by wild-type p53 adenoviral gene transfer in squamous cell carcinoma of the head and neck
-
Liu TJ, el-Naggar AK, McDonnell TJ, Steck KD, Wang M, Taylor DL, Clayman GL: Apoptosis induction mediated by wild-type p53 adenoviral gene transfer in squamous cell carcinoma of the head and neck. Cancer Res 55:3117-3122, 1995.
-
(1995)
Cancer Res
, vol.55
, pp. 3117-3122
-
-
Liu, T.J.1
El-Naggar, A.K.2
McDonnell, T.J.3
Steck, K.D.4
Wang, M.5
Taylor, D.L.6
Clayman, G.L.7
-
67
-
-
0027499524
-
Prolonged cell cycle delay in radioresistant human cell lines transfected with acivated ras oncogene and/or simian virus 40 T-antigen
-
Su LN, Little JB: Prolonged cell cycle delay in radioresistant human cell lines transfected with acivated ras oncogene and/or simian virus 40 T-antigen. Radiat Res 133:73-79, 1993.
-
(1993)
Radiat Res
, vol.133
, pp. 73-79
-
-
Su, L.N.1
Little, J.B.2
-
69
-
-
0018092001
-
The action of caffeine on X-irradiated HeLa cells. III. enhancement of X-ray induced killing during G2 arrest
-
Busse PM, Bose SK: The action of caffeine on X-irradiated HeLa cells. III. enhancement of X-ray induced killing during G2 arrest. Radiat Res 76:292-307, 1978.
-
(1978)
Radiat Res
, vol.76
, pp. 292-307
-
-
Busse, P.M.1
Bose, S.K.2
-
70
-
-
0029025461
-
Gene-specific and strand-specific DNA repair in the G1 and G2 phases of the cell cycle
-
Peterson L, Orren D, Bohr V: Gene-specific and strand-specific DNA repair in the G1 and G2 phases of the cell cycle. Mol Cell Biol 15:3731-3737, 1995.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 3731-3737
-
-
Peterson, L.1
Orren, D.2
Bohr, V.3
-
71
-
-
0026485696
-
Effects of ionizing radiation on cyclin expression in HeLa cells
-
Muschel RJ, Zhang HB, Iliakis G, McKenna WG: Effects of ionizing radiation on cyclin expression in HeLa cells. Radiat Res 132:153-157, 1992.
-
(1992)
Radiat Res
, vol.132
, pp. 153-157
-
-
Muschel, R.J.1
Zhang, H.B.2
Iliakis, G.3
McKenna, W.G.4
-
73
-
-
0029140452
-
Cyclin-dependent kinases. CAK-handed kinase activation
-
Clarke P: Cyclin-dependent kinases. CAK-handed kinase activation. Curr Biol 5:40-42, 1995.
-
(1995)
Curr Biol
, vol.5
, pp. 40-42
-
-
Clarke, P.1
-
74
-
-
0025922083
-
cdc2/cyclin B complex in vitro by human CDC25 protein
-
cdc2/cyclin B complex in vitro by human CDC25 protein. Nature 351:242-245, 1991.
-
(1991)
Nature
, vol.351
, pp. 242-245
-
-
Strausfeld, U.1
Labbe, J.C.2
Fesquet, D.3
Cavadore, J.C.4
Picard, A.5
Sadhu, K.6
Russell, P.7
Doree, M.8
-
75
-
-
0025938467
-
The CDC25 protein contains an intrinsic phosphatase activity
-
Dunphy WG, Kumagai A: The CDC25 protein contains an intrinsic phosphatase activity. Cell 67:189-196, 1991.
-
(1991)
Cell
, vol.67
, pp. 189-196
-
-
Dunphy, W.G.1
Kumagai, A.2
-
76
-
-
0027509501
-
Phosphorylation and activation of human CDC25-C by cdc2 -cyclin B and its involvement in the self-amplification of MPF at mitosis
-
Hoffmann I, Clarke PR, Marcote MJ, Karsenti E, Draetta G: Phosphorylation and activation of human CDC25-C by cdc2 -cyclin B and its involvement in the self-amplification of MPF at mitosis. EMBO J 12:53-63, 1993.
-
(1993)
EMBO J
, vol.12
, pp. 53-63
-
-
Hoffmann, I.1
Clarke, P.R.2
Marcote, M.J.3
Karsenti, E.4
Draetta, G.5
-
77
-
-
0026616796
-
cdc2-cyclin B complex by the human weel tyrosine kinase
-
cdc2-cyclin B complex by the human weel tyrosine kinase. Science 257:1955-1957, 1992.
-
(1992)
Science
, vol.257
, pp. 1955-1957
-
-
Parker, L.L.1
Piwnica-Worms, H.2
-
79
-
-
0025021753
-
Mutation of fission yeast cell cycle control genes abolishes dependence of mitosis on DNA replication
-
Enoch T, Nurse P: Mutation of fission yeast cell cycle control genes abolishes dependence of mitosis on DNA replication. Cell 60:665-673, 1990.
-
(1990)
Cell
, vol.60
, pp. 665-673
-
-
Enoch, T.1
Nurse, P.2
-
80
-
-
0026587204
-
The weel protein kinase is required for radiation-induced mitotic delay
-
Rowley R, Hudson J, Young PG: The weel protein kinase is required for radiation-induced mitotic delay. Nature 356:353-355, 1992.
-
(1992)
Nature
, vol.356
, pp. 353-355
-
-
Rowley, R.1
Hudson, J.2
Young, P.G.3
-
81
-
-
0026482601
-
Fission yeast genes involved in coupling mitosis to completion of DNA replication
-
Enoch T, Carr AM, Nurse P: Fission yeast genes involved in coupling mitosis to completion of DNA replication. Genes Dev 6:2035-2046, 1992.
-
(1992)
Genes Dev
, vol.6
, pp. 2035-2046
-
-
Enoch, T.1
Carr, A.M.2
Nurse, P.3
-
82
-
-
0023835721
-
The ras oncogenes increase the intrinsic resistance of NIH 3T3 cells to ionizing radiation
-
Sklar MD: The ras oncogenes increase the intrinsic resistance of NIH 3T3 cells to ionizing radiation. Science 239:645-647, 1988.
-
(1988)
Science
, vol.239
, pp. 645-647
-
-
Sklar, M.D.1
-
83
-
-
0025282789
-
The role of the H-ras oncogene in radiation resistance and metastasis
-
McKenna W, Weiss M, Bakanauskas V, Sandler H, Kelsten M, Biaglow J, Endlich B, Ling C, Muschel R: The role of the H-ras oncogene in radiation resistance and metastasis. Int J Radiat Oncol Biol Phys 18:849-860, 1990.
-
(1990)
Int J Radiat Oncol Biol Phys
, vol.18
, pp. 849-860
-
-
McKenna, W.1
Weiss, M.2
Bakanauskas, V.3
Sandler, H.4
Kelsten, M.5
Biaglow, J.6
Endlich, B.7
Ling, C.8
Muschel, R.9
-
84
-
-
0026129706
-
2 delay in radiation-resistant cells obtained by transformation of primary rat embryo cells with the oncogenes v-myc and H-ras
-
2 delay in radiation-resistant cells obtained by transformation of primary rat embryo cells with the oncogenes v-myc and H-ras. Radiat Res 125:283-287, 1991.
-
(1991)
Radiat Res
, vol.125
, pp. 283-287
-
-
McKenna, W.G.1
Iliakis, G.2
Weiss, M.C.3
Bernhard, E.J.4
Muschel, R.J.5
-
85
-
-
0026069862
-
Cyclin B expression in HeLa cells during the G2 block induced by radiation
-
Muschel R, Zhang H, Iliakis G, McKenna W: Cyclin B expression in HeLa cells during the G2 block induced by radiation. Cancer Res 51:5113-5117, 1991.
-
(1991)
Cancer Res
, vol.51
, pp. 5113-5117
-
-
Muschel, R.1
Zhang, H.2
Iliakis, G.3
McKenna, W.4
-
86
-
-
0027537380
-
Differential effect of ionizing radiation on the expression of cyclin A and cyclin B in HeLa cells
-
Muschel RJ, Zhang HB, McKenna WG: Differential effect of ionizing radiation on the expression of cyclin A and cyclin B in HeLa cells. Cancer Res 53:1128-1135, 1993.
-
(1993)
Cancer Res
, vol.53
, pp. 1128-1135
-
-
Muschel, R.J.1
Zhang, H.B.2
McKenna, W.G.3
-
87
-
-
0028896811
-
Evidence for posttranscriptional regulation of cyclin B1 mRNA in the cell cycle and following irradiation in HeLa cells
-
Maity A, McKenna WG, Muschel RJ: Evidence for posttranscriptional regulation of cyclin B1 mRNA in the cell cycle and following irradiation in HeLa cells. EMBO J 14:603-609, 1995.
-
(1995)
EMBO J
, vol.14
, pp. 603-609
-
-
Maity, A.1
McKenna, W.G.2
Muschel, R.J.3
-
88
-
-
0029147449
-
Transient failure to dephosphorylate the cdc2-cyclin B1 complex accompanies radiation-induced G2 phase arrest in HeLa cells
-
Metting N, Little J: Transient failure to dephosphorylate the cdc2-cyclin B1 complex accompanies radiation-induced G2 phase arrest in HeLa cells. Radiat Res 143:286-292, 1995.
-
(1995)
Radiat Res
, vol.143
, pp. 286-292
-
-
Metting, N.1
Little, J.2
-
89
-
-
0029883288
-
Radiation with 1 Gy prevents the activation of the mitotic inducers mitosis-promoting factors (MPF) and cdc-25 in HeLa cells
-
Barth H, Hoffmann I, Kinzel V: Radiation with 1 Gy prevents the activation of the mitotic inducers mitosis-promoting factors (MPF) and cdc-25 in HeLa cells. Cancer Res 56:2268-2272, 1996.
-
(1996)
Cancer Res
, vol.56
, pp. 2268-2272
-
-
Barth, H.1
Hoffmann, I.2
Kinzel, V.3
-
90
-
-
0028670266
-
The effect of radiation on G2 blocks, cyclin B expression, and cdc2 expression in human squamous cell lines with different radiosensitivities
-
Smeets M, Mooren E, Begg A: The effect of radiation on G2 blocks, cyclin B expression, and cdc2 expression in human squamous cell lines with different radiosensitivities. Radiother Oncol 33:217-227, 1994.
-
(1994)
Radiother Oncol
, vol.33
, pp. 217-227
-
-
Smeets, M.1
Mooren, E.2
Begg, A.3
-
91
-
-
0028353634
-
Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair
-
Weinert TA, Kiser GL, Hartwell LH: Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair. Genes Dev 8:652-665, 1994.
-
(1994)
Genes Dev
, vol.8
, pp. 652-665
-
-
Weinert, T.A.1
Kiser, G.L.2
Hartwell, L.H.3
-
92
-
-
0029977376
-
Reducing the radiation-induced G2 delay causes HeLa cells to undergo apoptosis instead of mitotic death
-
Bernhard EJ, Muschel RJ, Bakanauskas VJ, McKenna WG: Reducing the radiation-induced G2 delay causes HeLa cells to undergo apoptosis instead of mitotic death. Int J Radiat Biol 69:575-584, 1996.
-
(1996)
Int J Radiat Biol
, vol.69
, pp. 575-584
-
-
Bernhard, E.J.1
Muschel, R.J.2
Bakanauskas, V.J.3
McKenna, W.G.4
-
93
-
-
0028094424
-
The role of cell cycle progression in cisplatin-induced apoptosis in Chinese hamster ovary cells
-
Demarcq C, Bunch R, Creswell D, Eastman A: The role of cell cycle progression in cisplatin-induced apoptosis in Chinese hamster ovary cells. Cell Growth Differ 5:983-993, 1994.
-
(1994)
Cell Growth Differ
, vol.5
, pp. 983-993
-
-
Demarcq, C.1
Bunch, R.2
Creswell, D.3
Eastman, A.4
-
94
-
-
0027941355
-
Concentration-dependent differences in the mechanisms by which caffeine potentiates etoposide cytotoxicity in HeLa cells
-
Lock RB, Galperina OV, Feldhoff RC, Rhodes LJ: Concentration-dependent differences in the mechanisms by which caffeine potentiates etoposide cytotoxicity in HeLa cells. Cancer Res 54:4933-4939, 1994.
-
(1994)
Cancer Res
, vol.54
, pp. 4933-4939
-
-
Lock, R.B.1
Galperina, O.V.2
Feldhoff, R.C.3
Rhodes, L.J.4
-
95
-
-
0028913739
-
A p53-dependent mouse spindle checkpoint
-
Cross SM, Sanchez CA, Morgan CA, Schimke MK, Ramel S, Idzerda RL, Raskind WH, Reid BJ: A p53-dependent mouse spindle checkpoint. Science 267:1353-1356, 1995.
-
(1995)
Science
, vol.267
, pp. 1353-1356
-
-
Cross, S.M.1
Sanchez, C.A.2
Morgan, C.A.3
Schimke, M.K.4
Ramel, S.5
Idzerda, R.L.6
Raskind, W.H.7
Reid, B.J.8
-
96
-
-
0029001624
-
p53 involvement in control of G2 exit of the cell cycle: Role in DNA damage-induced apoptosis
-
Guillouf C, Rosselli F, Krishnaraju K, Moustacchi E, Hoffman B, Liebermann DA: p53 involvement in control of G2 exit of the cell cycle: Role in DNA damage-induced apoptosis. Oncogene 10:2263-2270, 1995.
-
(1995)
Oncogene
, vol.10
, pp. 2263-2270
-
-
Guillouf, C.1
Rosselli, F.2
Krishnaraju, K.3
Moustacchi, E.4
Hoffman, B.5
Liebermann, D.A.6
-
97
-
-
0028936626
-
Differential sensitivity of p53- and p53+ cells to caffeine-induced radiosensitization and override of G2 delay
-
Powell S, Defrank J, Connell P, Edgan M, Preffer F, Dombkowski D, Tang W, Friend S: Differential sensitivity of p53- and p53+ cells to caffeine-induced radiosensitization and override of G2 delay. Cancer Res 55:1643-1648, 1995.
-
(1995)
Cancer Res
, vol.55
, pp. 1643-1648
-
-
Powell, S.1
Defrank, J.2
Connell, P.3
Edgan, M.4
Preffer, F.5
Dombkowski, D.6
Tang, W.7
Friend, S.8
-
99
-
-
0028901034
-
Disruption of p53 function sensitizes breast cancer MCF 7 cells to cisplatin and pentoxifylline
-
Fan S, Smith M, Rivet D, Duba D, Zhan Q, Kohn K, Fornace A, O'Connor P: Disruption of p53 function sensitizes breast cancer MCF 7 cells to cisplatin and pentoxifylline. Cancer Res 55:1649-1654, 1995.
-
(1995)
Cancer Res
, vol.55
, pp. 1649-1654
-
-
Fan, S.1
Smith, M.2
Rivet, D.3
Duba, D.4
Zhan, Q.5
Kohn, K.6
Fornace, A.7
O'Connor, P.8
-
100
-
-
0028973293
-
Ras CAAX peptidomimetic FTI-277 selectively blocks oncogenic ras signalling by inducing cytoplasmic accumulation of inactive ras-raf complexes
-
Lerner E, Qian Y, Blaskovich M, Fossum RD, Vogt A, Sun J, Cox A, Der C, Hamilton A, Sebti S: Ras CAAX peptidomimetic FTI-277 selectively blocks oncogenic ras signalling by inducing cytoplasmic accumulation of inactive ras-raf complexes. J Biol Chem 270:26802-26806, 1995.
-
(1995)
J Biol Chem
, vol.270
, pp. 26802-26806
-
-
Lerner, E.1
Qian, Y.2
Blaskovich, M.3
Fossum, R.D.4
Vogt, A.5
Sun, J.6
Cox, A.7
Der, C.8
Hamilton, A.9
Sebti, S.10
-
101
-
-
0016258505
-
Radiation effects on DNA chain growth in mammalian cells
-
Watanabe I: Radiation effects on DNA chain growth in mammalian cells. Radiat Res 58:541-556, 1974.
-
(1974)
Radiat Res
, vol.58
, pp. 541-556
-
-
Watanabe, I.1
-
102
-
-
0016590685
-
Effects of ionizing radiation on DNA replication in cultured mammalian cells
-
Makino F, Okada S: Effects of ionizing radiation on DNA replication in cultured mammalian cells. Radiat Res 62:37-51, 1975.
-
(1975)
Radiat Res
, vol.62
, pp. 37-51
-
-
Makino, F.1
Okada, S.2
-
103
-
-
0017238711
-
Formation of nascent DNA molecules during inhibition of replicon initiation in mammalian cells
-
Painter RB, Young BR: Formation of nascent DNA molecules during inhibition of replicon initiation in mammalian cells. Biochim Biophys Acta 418:146-153, 1976.
-
(1976)
Biochim Biophys Acta
, vol.418
, pp. 146-153
-
-
Painter, R.B.1
Young, B.R.2
-
104
-
-
0028329595
-
Radiation effects on DNA synthesis in a defined chromosomal replicon
-
Larner JM, Lee H, Hamlin JL: Radiation effects on DNA synthesis in a defined chromosomal replicon. Mol Cell Biol 14:1901-1908, 1994.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 1901-1908
-
-
Larner, J.M.1
Lee, H.2
Hamlin, J.L.3
-
105
-
-
20644431676
-
Persistent inhibition of DNA synthesis in cells obtained by transformation of primary rat embryo fibroblasts with oncogenes H-ras and v-myc
-
Wang Y, Cheong N, Iliakis G: Persistent inhibition of DNA synthesis in cells obtained by transformation of primary rat embryo fibroblasts with oncogenes H-ras and v-myc. Cancer Res 53:1993.
-
Cancer Res
, vol.53
, pp. 1993
-
-
Wang, Y.1
Cheong, N.2
Iliakis, G.3
-
106
-
-
0026573626
-
Prolonged inhibition by X-rays of DNA synthesis in cells obtained by transformation of primary rat embryo fibroblasts with oncogenes H-ras and v-myc
-
Wang Y, Iliakis G: Prolonged inhibition by X-rays of DNA synthesis in cells obtained by transformation of primary rat embryo fibroblasts with oncogenes H-ras and v-myc. Cancer Res 52:508-514, 1992.
-
(1992)
Cancer Res
, vol.52
, pp. 508-514
-
-
Wang, Y.1
Iliakis, G.2
-
107
-
-
0029281835
-
DNA structure checkpoints in fission yeast
-
Carr AM: DNA structure checkpoints in fission yeast. Semin Cell Biol 6:65-72, 1995.
-
(1995)
Semin Cell Biol
, vol.6
, pp. 65-72
-
-
Carr, A.M.1
-
109
-
-
0026528685
-
Cancer susceptibility in ataxia-telangiectasia
-
Peterson R, Funkhouser J, Tuck-Muller C, Gatti R: Cancer susceptibility in ataxia-telangiectasia. Leukemia 6(Suppl 1):8-13, 1992.
-
(1992)
Leukemia
, vol.6
, Issue.1 SUPPL.
, pp. 8-13
-
-
Peterson, R.1
Funkhouser, J.2
Tuck-Muller, C.3
Gatti, R.4
-
110
-
-
0028593976
-
Cellular radiosensitivity in ataxia-telangiectasia
-
Thacker J: Cellular radiosensitivity in ataxia-telangiectasia. Int J Radiat Biol 66:S87-S96, 1994.
-
(1994)
Int J Radiat Biol
, vol.66
-
-
Thacker, J.1
-
111
-
-
0028932603
-
Cell cycle regulation in response to DNA damage in mammalian cells; a historical perspective
-
Murname JP: Cell cycle regulation in response to DNA damage in mammalian cells; a historical perspective. Cancer Met Rev 14:17-29, 1995.
-
(1995)
Cancer Met Rev
, vol.14
, pp. 17-29
-
-
Murname, J.P.1
-
112
-
-
0028827312
-
The complete sequence of the coding region of the ATM gene reveals similarity to cell cycle regulators in different species
-
Savitsky K, Sfez S, Tagle DA, Ziv Y, Sartiel A, Collins FS, Shiloh Y, Rotman G: The complete sequence of the coding region of the ATM gene reveals similarity to cell cycle regulators in different species. Hum Mol Genet 4:2025-2032, 1995.
-
(1995)
Hum Mol Genet
, vol.4
, pp. 2025-2032
-
-
Savitsky, K.1
Sfez, S.2
Tagle, D.A.3
Ziv, Y.4
Sartiel, A.5
Collins, F.S.6
Shiloh, Y.7
Rotman, G.8
-
113
-
-
0023244806
-
Breast and other cancers in families with ataxia-telangiectasia
-
Swift M, Reitnauer P, Morrell D, Chase C: Breast and other cancers in families with ataxia-telangiectasia. N Engl J Med 316:1289-1294, 1987.
-
(1987)
N Engl J Med
, vol.316
, pp. 1289-1294
-
-
Swift, M.1
Reitnauer, P.2
Morrell, D.3
Chase, C.4
-
114
-
-
0026409331
-
Incidence of cancer in 161 families affected by ataxia-telangiectasia
-
Swift M, Morrell D, Massey R, Chase C: Incidence of cancer in 161 families affected by ataxia-telangiectasia. N Engl J Med 325:1831-1836, 1991.
-
(1991)
N Engl J Med
, vol.325
, pp. 1831-1836
-
-
Swift, M.1
Morrell, D.2
Massey, R.3
Chase, C.4
-
115
-
-
0026000309
-
Assessment of chronic gamma radiosensitivity as an in vitro assay for heterozygote identification of ataxia-telangiectasia
-
Weeks D, Paterson M, Lange K, Andrais B, Davis R, Yoder F, Gatti R: Assessment of chronic gamma radiosensitivity as an in vitro assay for heterozygote identification of ataxia-telangiectasia. Radiat Res 128:90-99, 1991.
-
(1991)
Radiat Res
, vol.128
, pp. 90-99
-
-
Weeks, D.1
Paterson, M.2
Lange, K.3
Andrais, B.4
Davis, R.5
Yoder, F.6
Gatti, R.7
-
116
-
-
0028880649
-
Ataxia-telangiectasia and cellular responses to DNA damage
-
Meyn M: Ataxia-telangiectasia and cellular responses to DNA damage. Cancer Res 55:5991-6001, 1995.
-
(1995)
Cancer Res
, vol.55
, pp. 5991-6001
-
-
Meyn, M.1
-
117
-
-
0029899035
-
The ATM gene and the radiobiology of ataxia-telangiectasia
-
Jorgenson TJ, Shiloh Y: The ATM gene and the radiobiology of ataxia-telangiectasia. Int J Radiat Biol 69:527-537, 1996.
-
(1996)
Int J Radiat Biol
, vol.69
, pp. 527-537
-
-
Jorgenson, T.J.1
Shiloh, Y.2
-
118
-
-
0026496885
-
A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia
-
Kastan MB, Zhan Q, El-Deiry WS, Carrier F, Jacks T, Walsh WV, Plundett BS, Vogenstein B, Fornace AJ Jr: A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia. Cell 71:587-597, 1992.
-
(1992)
Cell
, vol.71
, pp. 587-597
-
-
Kastan, M.B.1
Zhan, Q.2
El-Deiry, W.S.3
Carrier, F.4
Jacks, T.5
Walsh, W.V.6
Plundett, B.S.7
Vogenstein, B.8
Fornace Jr., A.J.9
-
119
-
-
0029093638
-
Nature of G1/S cell cycle checkpoint defect in ataxia-telangiectasia
-
Khanna K, Beamish H, Yan J, Hobson K, Williams R, Dunn I, Lavin M: Nature of G1/S cell cycle checkpoint defect in ataxia-telangiectasia. Oncogene 10:609-618, 1995.
-
(1995)
Oncogene
, vol.10
, pp. 609-618
-
-
Khanna, K.1
Beamish, H.2
Yan, J.3
Hobson, K.4
Williams, R.5
Dunn, I.6
Lavin, M.7
-
120
-
-
0028171182
-
The p53-dependent G1 cell cycle checkpoint pathway and ataxia-telangiectasia
-
Canman CE, Wolff AC, Chen C-Y, Fornace AJ Jr, Kastan MB: The p53-dependent G1 cell cycle checkpoint pathway and ataxia-telangiectasia. Cancer Res 54:5054-5058, 1994.
-
(1994)
Cancer Res
, vol.54
, pp. 5054-5058
-
-
Canman, C.E.1
Wolff, A.C.2
Chen, C.-Y.3
Fornace Jr., A.J.4
Kastan, M.B.5
-
121
-
-
0028213350
-
Radiosensitivity in ataxia-telangiectasia: Anomalies in radiation-induced cell cycle delay
-
Beamish H, Lavin MF: Radiosensitivity in ataxia-telangiectasia: Anomalies in radiation-induced cell cycle delay. Int J Radiat Biol 65:175-184, 1989.
-
(1989)
Int J Radiat Biol
, vol.65
, pp. 175-184
-
-
Beamish, H.1
Lavin, M.F.2
-
122
-
-
0029664616
-
Rad-dependent response of the chk-1 encoded protein kinase at the DNA damage checkpoint
-
Walworth N, Bernards R: Rad-dependent response of the chk-1 encoded protein kinase at the DNA damage checkpoint. Science 271:353-356, 1996.
-
(1996)
Science
, vol.271
, pp. 353-356
-
-
Walworth, N.1
Bernards, R.2
-
123
-
-
0030593033
-
Elledge S: Regulation of RAD53 by the ATM-like kinases MEC1 and TEL1 in yeast cell cycle checkpoint pathways
-
Sanchez Y, Desany B, Jones W, Liu Q, Wang B, Elledge S: Regulation of RAD53 by the ATM-like kinases MEC1 and TEL1 in yeast cell cycle checkpoint pathways. Science 271:357-360, 1996.
-
(1996)
Science
, vol.271
, pp. 357-360
-
-
Sanchez, Y.1
Desany, B.2
Jones, W.3
Liu, Q.4
Wang, B.5
-
124
-
-
0029977376
-
Reducing the radiation-induced G2 delay causes HeLa cells to undergo apoptosis instead of mitotic death
-
Bernhard EJ, Muschel RJ, Bakanauskas VJ, McKenna WG: Reducing the radiation-induced G2 delay causes HeLa cells to undergo apoptosis instead of mitotic death. Int J Radiat Biol 69:575-584, 1996.
-
(1996)
Int J Radiat Biol
, vol.69
, pp. 575-584
-
-
Bernhard, E.J.1
Muschel, R.J.2
Bakanauskas, V.J.3
McKenna, W.G.4
-
125
-
-
0027533043
-
Enhancement of radiation response of human carcinoma cells in culture by pentoxyfylline
-
Kim SH, Khil MS, Ryu S, Kim JH: Enhancement of radiation response of human carcinoma cells in culture by pentoxyfylline. Int J Radiat Oncol Biol Phys 25:61-65, 1992.
-
(1992)
Int J Radiat Oncol Biol Phys
, vol.25
, pp. 61-65
-
-
Kim, S.H.1
Khil, M.S.2
Ryu, S.3
Kim, J.H.4
|