17-β-estradiol increases expression of 52-kDa and 60-kDa SS-A/Ro autoantigens in human keratinocytes and breast cancer cell line MCF-7

Journal of Investigative Dermatology

Volumn 107, Issue 4, 1996, Pages 610-614

  Wang, Dunrui ^a   Chan, Edward K L ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Autoantibody; Estrogen; Gene expression

Indexed keywords

AUTOANTIBODY; ESTRADIOL; MESSENGER RNA;

ADULT; ARTICLE; AUTOIMMUNITY; BREAST CANCER; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; KERATINOCYTE; MALE; NEWBORN; PRIORITY JOURNAL;

EID: 0029842504     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1111/1523-1747.ep12584194     Document Type: Article

References (41)

1. Ansar Ahmed S, Aufdemorte TB, Chen JR, Montoya AI, Olive D, Talal N: Estrogen induces the development of autoantibodies and promotes salivary gland lymphoid infiltrates in normal mice. J Autoimmun 2:543-552, 1989
2. Ansar Ahmed S, Verthelyi D: Antibodies to cardiolipin in normal C57BL/6J mice: induction by estrogen but not dihydrotestosterone. J Autoimmun 6:265-279, 1993
3. Ben-Chetrit E, Chan EKL, Sullivan KF, Tan EM: A 52-kD protein is a novel component of the SS-A/Ro antigenic particle. J Exp Med 167:1560-1571, 1988
4. Ben-Chetrit E, Gaudy BJ, Tan EM, Sullivan KF: Isolation and characterization of a cDNA clone encoding the 60-kD component of the human SS-A/Ro ribonucleoprotein autoantigen. J Clin Invest 83:1284-1292, 1989
5. Burch JB, Evans MI, Friedman TM, O'Malley PJ: Two functional estrogen response elements are located upstream of the major chicken vitellogenin gene. Mol Cell Biol 8:1123-1131, 1988
6. Casciola-Rosen LA, Anhalt G, Rosen A: Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes. J Exp Med 179:1317-1330, 1994
7. Chan EKL: Basis for heterogeneity of SS-A/Ro autoantigens. In: Homma M, Sugai S, Tojo T, Miyasaka N, Akizuki M (eds.). Sjögren's Syndrome: State of the Art. Proceedings of the 4th International Symposium on Sjögren's Syndrome. Kugler Publications, Amsterdam, 1994, pp 125-129
8. Chan EKL, Buyon JP: The SS-A/Ro antigen. In: van Venrooij WJ, Maini RN (eds.). Manual of Biological Markers of Disease. Kluwer Academic Publishers, Dordrecht, The Netherlands, 1994, pp 1-18
9. Chan EKL, Di Donato F, Hamel JC, Tseng CE, Buyon JP: 52-kD SS-A/Ro: genomic structure and identification of an alternatively spliced transcript encoding a novel leucine zipper-minus autoantigen expressed in fetal and adult heart. J Exp Med 182:983-992, 1995
10. Chan EKL, Hamel JC, Buyon JP, Tan EM: Molecular definition and sequence motifs of the 52-kD component of human SS-A/Ro autoantigen. J Clin Invest 87:68-76, 1991
11. Chan EKL, Pollard KM: Antibodies to ribonucleoprotein particles by immunoblotting. In: Rose NR, Conway de Macario H, Fahey JL, Friedman H, Penn GM (eds.). Manual of Clinical Laboratory Immunology. American Society of Microbiology, Washington, DC, 1992, pp 755-761
12. Deutscher SL, Harley JB, Keene JD: Molecular analysis of the 60-kDa human Ro ribonucleoprotein. Proc Natl Acad Sci USA 85:9479-9483, 1988
13. Dörner T, Chaoui R, Feist E, Keyber G, Goldner B, Yamamoto K, Hiepe F: Significantly increased maternal and fetal autoantibody levels to 52kD Ro (SS-A) and La (SS-B) in complete congenital heart block. J Autoimmun 8:675-684, 1995
14. Dörner T, Hucko M, Mayet WJ, Trefzer U, Burmester G, Hiepe F: Enhanced membrane expression of the 52 kD Ro(SSA) and La(SSB) antigens by human keratinocytes induced by TNF alpha. Ann Rheum Dis 54:904-909, 1996
15. Dubik D, Shin RP: Mechanism of estrogen activation of c-myc oncogene expression. Oncogene 7:1587-1594, 1992
16. Furukawa F, Imamura S, Norris DA: Stimulation of anti-RNP antibody binding to cultured keratinocytes by estradiol. Arch Dermatol Res 283:258-261, 1991
17. Furukawa F, Kashihara-Sawami M, Lyons MB, Norris DA: Binding of antibodies to the extractable nuclear antigens SS-A/Ro and SS-B/La is induced on the surface of human keratinocytes by ultraviolet light (UVL): implications for the pathogenesis of photosensitive cutaneous lupus. J Invest Dermatol 94:77-85, 1990
18. Furukawa F, Lyons MB, Lee LA, Coulter SN, Norris DA: Estradiol enhances binding to cultured human keratinocytes of antibodies specific for SS-A/Ro and SS-B/La. Another possible mechanism for estradiol influence of lupus erythematosus. J Immunol 141:1480-1488, 1988
19. Goblet C, Prost E, Whalen RG: One-step amplification of transcripts in total RNA using the polymerase chain reaction. Nucleic Acids Res 17:2144, 1989
20. Hyder SM, Nawaz Z, Chiappetta C, Yokoyama K, Stancel GM: The protooncogene c-jun contains an unusual estrogen-inducible enhancer within the coding sequence. J Biol Chem 270:8506-8513, 1995
21. Hyder SM, Stancel GM, Nawar Z, McDonnell DP, Loose-Mitchell DS: Identification of an estrogen response element in the 3′-flanking region of the murine c-fos protooncogene. J Biol Chem 267:18047-18054, 1992
22. Itoh K, Itoh Y, Frank MB: Protein heterogeneity in the human Ro/SSA ribonucleo-proteins. J Clin Invest 87:177-186, 1991
23. Klein-Hitpass L, Ryffel GU, Heitlinger E, Cato AC: A 13 bp palindrome is a functional estrogen responsive element and interacts specifically with estrogen receptor. Nucleic Acids Res 16:647-663, 1988
24. Krishnan AV, Stathis P, Permuth SF, Tokes L, Feldman D: Bisphenol-A: an estrogenic substance is released from polycarbonate flasks during autoclaving. Endocrinology 132:2279-2286, 1993
25. Lahita RG, Bradlow L, Fishman J, Kunkel HG: Estrogen metabolism in systemic lupus erythematosus: patients and family members. Arthritis Rheum 25:843-846, 1982
26. Lahita RG, Bradlow HL, Kunkel HG, Fishman J: Alterations of estrogen metabolism in systemic lupus erythematosus. Arthritis Rheum 22:1195-1198, 1979
27. Levitz M, Young BK: Estrogens in pregnancy. Vitam Horm 35:109-147, 1977
28. McCauliffe DP, Sontheimer RD: Molecular characterization of the Ro/SS-A autoantigens. J Invest Dermatol 100:73S-79S, 1993
29. Niimi Y, Ioannides D, Buyon JP, Bystryn JC: Heterogeneity in the expression of Ro and La antigens in human skin. Arthritis Rheum 38:1271-1276, 1995
30. Pentecost BT, Mattheiss L, Dickerman HW, Kumar SA: Estrogen regulation of creatine kinase-B in the rat uterus. Mol Endocrinol 4:1000-1010, 1990
31. Rader MD, O'Brien C, Liu YS, Harley JB, Reichlin M: Heterogeneity of the Ro/SSA antigen. Different molecular forms in lymphocytes and red blood cells. J Clin Invest 83:1293-1298, 1989
32. Rajendran KG, Lopez T, Parikh I: Estrogenic effect of phenol red in MCF-7 cells is achieved through activation of estrogen receptor by interacting with a site distinct from the steroid binding site. Biochem Biophys Res Commun 142:724-731, 1987
33. Reichlin M: Autoantibodies to the RoRNP particles. Clin Exp Immunol 99:7-9, 1995
34. Shupnik MA, Rosenzweig BA: Identification of an estrogen-responsive element in the rat LH beta gene. DNA-estrogen receptor interactions and functional analysis. J Biol Chem 266:17084-17091, 1991
35. Soto AM, Chung KL, Sonnenschein C: The pesticides endosulfan, toxaphene, and dieldrin have estrogenic effects on human estrogen-sensitive cells. Environ Health Perspect 102:380-383, 1994
36. Sthoeger ZM, Bentwich Z, Zinger H, Mozes E: The beneficial effect of the estrogen antagonist, tamoxifen, on experimental systemic lupus erythematosus. J Rheumatol 21:2231-2238, 1994
37. Tan EM: Autoimmunity and apoptosis. J Exp Med 179:1083-1086, 1994
38. vom Saal FS, Nagel SC, Palanza P, Boechler M, Parmigiani S, Welshons WV: Estrogenic pesticides: binding relative to estradiol in MCF-7 cells and effects of exposure during fetal life on subsequent territorial behaviour in male mice. Toxicol Lett 77:343-350, 1995
39. Wang TT, Phang JM: Effects of estrogen on apoptotic pathways in human breast cancer cell line MCF-7. Cancer Res 55:2487-2489, 1995
40. Wolin SL, Steitz JA: The Ro small cytoplasmic ribonucleoproteins: identification of the antigenic protein and its binding site on the Ro RNAs. Proc Natl Acad Sci USA 81:1996-2000, 1984
41. Zhu J: Ultraviolet B irradiation and cytomegalovirus infection synergize to induce the cell surface expression of 52-kD Ro antigen. Clin Exp Immunol 103:47-53, 1996