Ultraviolet B irradiation and cytomegalovirus infection synergize to induce the cell surface expression of 52-kD/Ro antigen

Clinical and Experimental Immunology

Volumn 103, Issue 1, 1996, Pages 47-53

  Zhu, J ^a,b  

^a MCGILL UNIVERSITY   (Canada)

^b NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

Calreticulin; Cytomegalovirus; Fibroblasts; Irradiation; Ro autoantigens; Ultraviolet B

Indexed keywords

AUTOANTIBODY; RIBONUCLEOPROTEIN;

ARTICLE; CYTOMEGALOVIRUS INFECTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FIBROBLAST; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; PRIORITY JOURNAL; ULTRAVIOLET B RADIATION;

EID: 0030067628     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.1996.00912.x     Document Type: Article

References (47)

1. Deutscher S, Harlet JB, Keene JD. Molecular analysis of the 60-kDa human Ro rionucleoprotein. Proc Natl Acad Sci USA 1988; 85:9479-83.
2. Ben-Chetrit E, Gandy BJ, Tan EM, Sullivan KF. Isolation and characterization of a cDNA clone encoding the 60-kD component of the human SS-A/Ro ribonucleoprotein autoantigen. J Clin Invest 1989;83:1284-92.
3. Chan EKL, Hamel JC, Buyon JP, Tan EM. Molecular definition and sequence motifs of the 52-kD component of human SS-A/Ro autoantigen. J Clin Invest 1991; 87:68-79.
4. McCauliffe DP, Lux FA, Lieu TS et al. Molecular cloning, expression, and chromosome 19 localization of a human Ro/SS-A autoantigen. J Clin Invest 1990; 85:1379-91.
5. Reichlin M, Harley J. Antibodies to Ro (SSA) and the heterogeneity of systemic lupus erythematosus. J Rheumatol 1987; 14:112-7.
6. Hunter FA, Barger BD, Schrohenloher R et al. Autoantibodies to calreticulin in the sera of systemic lupus erythematosus. Arthritis Rheum 1991; 34 (Suppl. 9):S75.
7. Rokeach LA, Haselby JA, Meilof JF et al. Characterization of the autoantigen calreticulin. J Immunol 1991; 147:3031-9.
8. LeFeber WP, Norris DA, Ryan SR et al. Ultraviolet light induces binding of antibodies to selected nuclear antigens on cultured human keratinocytes. J Clin Invest 1984; 74:1545-51.
9. Furukawa F, Kashihara-Sawami M, Lyons MB, Norris DA. Binding of antibodies to the extractable nuclear antigens SS-A/Ro and SS-B/La is induced on the surface of human keratinocytes by ultraviolet light (UVL): implications for the pathogenesis of photosensitive cutaneous lupus. J Invest Dermatol 1990; 94:77-85.
10. Jones SK. Ultraviolet radiation (UVR) induces cell-surface Ro/SSA antigen expression by human keratinocytes in vitro, a possible mechanism for the UVR induction of cutaneous lupus lesions. Br J Dermatol 1992; 126:546-53.
11. Golan TD, Elkon KB, Gharavi AE, Krueger JG. Enhanced membrane binding of autoantibodies to cultured keratinocytes of systemic lupus erythematosus patients after ultraviolet B/ultraviolet A irradiation. J Clin Invest 1992; 90:1067-76.
12. Furukawa F, Lyons MB, Lee LA et al. Estradiol enhances binding to cultured human keratinocytes of antibodies specific for SS-A/Ro and SS-B/La. J Immunol 1988; 141:1480-8.
13. Baboonian C, Venables PWJ, Booth J et al. Virus infection induces redistribution and membrane localization of the nuclear antigen La (SSB): a possible mechanism for autoimmunity. Clin Exp Immunol 1989; 78:454-9.
14. Sharpe NG, Isenberg D, Williams DG, Latchman DS. Elevation of the levels of SmB, B′ and D proteins but not that of the La (SS-B) antigen during HSV infections. J Autoimmun 1989; 2:701-8.
15. Gold E, Nankervis GA. Cytomegalovirus. In: Evans AS, ed. Viral infections of humans: epidemiology and control, 2nd edn. New York: Plenum Press, 1982: 167-86.
16. Alford CA, Britt WJ. Cytomegalovirus. In: Fields BN, Knipe DM, eds. Virology. New York: Raven Press, 1990: 1981-2010.
17. Pincus T, Steinberg AD, Blacklow NR, Decker JL. Reactivities of systemic lupus erythematosus sera with cellular and virus antigen preparations. Arthritis Rheum 1978; 21:873-9.
18. Zhang X, Xu HT, Zhang CY et al. Immunomodulation of human cytomegalovirus infection on interferon system in patients with systemic lupus erythematosus. J Tongji Med Uni 1991; 11:126-8.
19. Vasquez V, Barzaga RA, Cunha BA. Cytomegalovirus-induced flare of systemic lupus erythematosus. Heart Lung 1992; 21:407-8.
20. Bulpitt KJ, Brahn E. Systemic lupus erythematosus and concurrent cytomegalovirus vasculities: diagnosis by antemortem skin biopsy. J Rheumatol 1989; 16:677-80.
21. Lord PCW, Rothschild CB, DeRose RT, Kilpatrick BA. Human cytomegalovirus RNAs immunoprecipitated by multiple systemic lupus erythematosus antisera. J Gen Virol 1989; 70:2383-96.
22. Zhu, JH, Newkirk MM. Viral induction of the human autoantigen calreticulin. Clin Invest Med 1994; 17:196-205.
23. Sissons JGP, Borysiewica LK, Rodgers B, Scott D. Cytomegalovirus - its cellular immunology and biology. Immunol Today 1986; 7:57-61.
24. Apperley JF, Goldman JM. Cytomegalovirus: biology, clinical features and methods for diagnosis. Bone Marrow Transplant 1988; 3:253-64.
25. Iton K, Iton Y, Frank MB. Protein heterogeneity in the human Ro/ SSA ribonucleoproteins. The 52- and 60-Kd Ro/SSA autoantigens are encoded by separate genes. J Clin Invest 1991; 87:177-86.
26. Lovering R, Hanson IM, Borden KLB et al. Identification and preliminary characterization of a protein motif related to the zinc linger. Proc Natl Acad Sci USA 1993; 90:2112-6.
27. Blange I, Ringertz NR, Pettersson I. Identification of antigenic regions of the human 52kDa Ro/SS-A protein recognized by patient sera. J Autoimmun 1994; 7:263-74.
28. Kastner P, Perez A, Lutz Y et al. Structure, localization and transcriptional properties of two classes of retinoic acid receptor α fusion proteins in acute promyeolocytic leukermia (APL): structural similarities with a new family of oncoproteins. EMBO J 1992; 11:629-42.
29. Casciola-Rosen LA, Anhalt G, Rosen A. Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes. J Exp Med 1994; 179:1317-30.
30. Umansky SR, Korol BA, Nelipovich PA. In vivo DNA degradation in thymocytes of r-irradiated or hydrocortisone-treated rats. Biochem Biophys Acta 1981; 655:9-17.
31. Gobe GC, Axelsen RA, Harmon BV, Allan DJ. Cell death by apoptosis following X-irradiation of the foetal and neonatal rat kidney. Int J Radiat Biol 1988; 54:567-76.
32. Mosser DD, Martin LH. Induced thermotolerance to apoptosis in a human T lymphocyte cell line. J Cell Physiol 1992; 151:561-70.
33. Levine B, Huang Q, Isaacs JT et al. Conversion of lytic to persistent alphavirus infection by the bcl-2 cellular oncogene. Nature 1993; 361:739-41.
34. Dawson CW, Eliopoulos AG, Dawson J, Young LS. BHRF1, a viral homologue of the Bcl 2 oncogene, disturbs epithelial cell differentiation. Oncogene 1995; 10:69-77.
35. Booth C, Koch GLE. Perturbation of cellular calcium induces secretion of luminal ER proteins. Cell 1989; 59:729-37.
36. Nguyen TQ, Capra JD, Sontheimer RD. Calreticulin is transcriptionally regulated by heat shock (abstra). Clin Res 1993; 41:443A.
37. McCauliffe DP, Yang YS, Wilson J et al. The 5′ flanking sequence region of the human calreticulin gene shares homology with the human GRP78, GRP94, and protein disulfide isomerase promoters. J Biol Chem 1992; 267:2557-62.
38. Winfield JB. Stress proteins, arthritis, and autoimmunity. Arthritis Rheum 1989; 32:1497-504.
39. Winrow VR, McLean L, Morris CJ, Blake DR. The heat shock protein response and its role in inflammatory disease. Ann Rheum Dis 1990; 49:128-32.
40. Schlesinger ML. Heat shock proteins. J Biol Chem 1990; 265:12111-4.
41. Erkeller-Yuksel FM, Isenberg DA, Dhillon VB et al. Surface expression of heat shock protein 90 by blood mononuclear cells from patients with systemic lupus erythematosus. J Autoimmun 1992; 5:803-14.
42. Peek P, Westphal JR, Pruijn JGM et al. Adenovirus infection induces loss of HLA class I and CD3 antigens, but does not induce cell surface presentation of the La (SS-B) autoantigen. Clin Exp Immunol 1994; 96:395-402.
43. Chretien P, Soulic E, Johanet C, Abuaf N. Comparisons of double immunodiffusion, ELISA, Western blot and cape blot for the detection of anti-SSA antibody: study of anti-SSA prevalence in systemic lupus erythematosus. J Autoimmun 1994; 7:397-88.
44. McCauliffe DP, Lux F, Lieu TS et al. Ro/SS-A and the pathogenic significance of its antibodies. J Autoimmun 1989; 2:375-81.
45. Sontheimer RD, McCauliffe DP, Pathogenesis of anti-Ro/SS-A autoantibody-associated cutaneous lupus erythematosus. Dermatol Clin 1990; 8:751-8.
46. Lee LA, Weslon WL. New findings in neonatal lupus syndrome. Am J Dis Child 1984; 138:233-6.
47. Ben-Chetrit E. The molecular basis of the SSA/Ro antigens and the clinical significance of their autoantibodies. Br J Dermatol 1993; 32:396-402.