Monozygotic twins display differences in their allospecific cytotoxic T-cell repertoire

Scandinavian Journal of Immunology

Volumn 44, Issue 6, 1996, Pages 638-642

  Reisaeter A V ^a   Brinchmann, J E ^a   Lundin, K E A ^a   Thorsby, E ^a  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

HLA ANTIGEN; T LYMPHOCYTE RECEPTOR;

ADULT; ARTICLE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; FEMALE; HUMAN; HUMAN CELL; MALE; MONOZYGOTIC TWINS; NORMAL HUMAN; PRIORITY JOURNAL; STEM CELL;

EID: 0029838791     PISSN: 03009475     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-3083.1996.d01-357.x     Document Type: Article

References (23)

1. Jameson SC, Hogquist KA, Bevan MJ. Positive selection of thymocytes. Ann Rev Immunol 1995;13:93-126.
2. Allen PM. Peptides in positive and negative selection: A delicate balance. Cell 1994;76:593-6.
3. Sprent J. T and B memory cells. Cell 1994;76:315-22.
4. Tough DF, Borrow P, Sprent J. Induction of bystander T cell proliferation by viruses and type I interferon in vivo. Science 1996;272:1947-50.
5. Sherman LA, Chattopadhyay S. The molecular basis of allorecognition. Ann Rev Immunol 1993;11:385-402.
6. Gjertsen HA, Lundin KEA, Hansen T, Thorsby E. T cells specific for viral antigens presented by HLA-Dw4 recognize DR13 on allogeneic cells: a possible mechanism for induction of rejection. Transplant Immunology 1993;1:126-31.
7. Ignatowicz L, Kappler J, Marrack P. The repertoire of T cells shaped by a single MHC/peptide ligand. Cell 1996;84:521-9.
8. Burrows SR, Khanna R, Burrows JM, Moss DJ. An alloresponse in humans is dominated by cytotoxic T lymphocytes (CTL) cross-reactive with a single Epstein-Barr virus CTL epitope: Implications for graft-versus-host disease. J Exp Med 1994;179:1155-61.
9. Vartdal F, Gaudernack G, Funderud S et al. HLA class I and II typing using cells positively selected from blood by immunomagnetic isolation - a fast and reliable technique. Tissue Antigens 1986;28:301-12.
10. Fischer Lindahl K, Wilson DB. Histocompatibility antigen-activated cytotoxic T lymphocytes. I. Estimates of the absolute frequency of killer cells generated in vitro. J Exp Med 1977;145:500-7.
11. Zhang L, Li SG, Vandekerckhove B, Termijtelen A, van Rood JJ, Claas FHJ. Analysis of cytotoxic T cell precursor frequencies directed against individual HLA-A and -B alloantigens. J Immunol Methods 1989;121:39-45.
12. Taswell C. Limiting dilution assays for the determination of immunocompetent cell frequencies. I. Data analysis. J Immunol 1981;126:1614-19.
13. Strijbosch LWG, Buurman WA, Does RJMM, Zinken PH, Groenewegen G. Limiting dilution assays. Experimental design and statistical analysis J Immunol Methods 1987;97:133-40.
14. Sharrock CEM, Man S, Wanachiwanawin W, Batchelor JR. Analysis of the alloreactive T cell repertoire in man. 1. Differences in precursor frequency for cytotoxic T cell responses against allogeneic MHC molecules in unrelated individuals. Transplantation 1987;43:699-703.
15. Davey MP, Meyer MM, Bakke AC. T cell receptor Vβ gene expression in monozygotic twins. Discordance in CD8 subset and in disease states. J Immunol 1994;152:315-21.
16. Gulwani-Akolkar B, Shalon L, Akolkar PN, Fisher SE, Silver J. Analysis of the peripheral blood T-cell receptor (TCR) repertoire in monozygotic twins discordant for Crohn's disease. Autoimmunity 1994;17:241-8.
17. Rebai N, Pantaleo G, Demarest JF et al. Analysis of the T cell receptor beta-chain variable region (V-β) repertoire in monozygotic twins discordant for human immunodeficiency virus: Evidence for perturbations of specific Vβ segments in CD4+ T cells of the virus-positive twins. Proc Natl Acad Sci 1994; 91:1529-33.
18. Brinchmann JE, Dobloug JH, Heger BH, Haaheim LL, Sannes M, Egeland T. Expression of costimulatory molecule CD28 on T cells in human immunodeficiency virus type 1 infection: functional and clinical correlations. J Infect Dis 1994;169:730-8.
19. Azuma M, Phillips JH, Lanier LL. CD28- T lymphocytes. J Immunol 1993;150:1147-59.
20. Brinchmann JE, Janson CH, Klem LB, Haaheim LL, Spurkland A. Strict adherence to a common rank order of T cell receptor Vβ usage in human leucocyte antigen disparate individuals. Scand J Immunol 1996;44:179-84.
21. Breur-Vriesendorp BS, Ivanyi P. Individual differences in the cytotoxic T lymphocyte respons in man to public HLA determinants. Cell Immunol 1986;103:252-71.
22. Maruya E, Takemoto S, Terasaki PI. HLA matching: Identification of permissible HLA mismatches. In: Terasaki PI, Cecka JM, eds. Clinical Transplants. Los Angeles: UCLA Tissue Typing Laboratory, 1994:511-20.
23. Doxiadis HN, Smits JMA, Stobbe I et al. Taboo HLA mismatches in Cadaveric Renal Transplantation: Definition, analysis, and possible implications. Transplant Proc1996;28:224.