Processing and activation of CMH-1 by granzyme B

Journal of Biological Chemistry

Volumn 271, Issue 18, 1996, Pages 10816-10820

  Gu, Yong ^a   Sarnecki, Charlyn ^a   Fleming, Mark A ^a   Lippke, Judith A ^a   Chris Bleackley, R ^b   Su, Michael S S ^a  

^a VERTEX PHARMACEUTICALS   (United States)

^b UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE PROTEINASE; GRANZYME B; INTERLEUKIN 1BETA CONVERTING ENZYME; SERINE PROTEINASE;

ANIMAL CELL; ARTICLE; CATALYSIS; CELL KILLING; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PURIFICATION; ENZYME REGULATION; ESCHERICHIA COLI; NONHUMAN; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CASPASE 7; CASPASES; CATALYSIS; CELL DEATH; CELL LINE; CYSTEINE ENDOPEPTIDASES; DNA, COMPLEMENTARY; ENZYME ACTIVATION; GRANZYMES; HYDROLYSIS; MOLECULAR SEQUENCE DATA; PROTEIN PROCESSING, POST-TRANSLATIONAL; SERINE ENDOPEPTIDASES; SUBSTRATE SPECIFICITY; T-LYMPHOCYTES, CYTOTOXIC;

EID: 17544378125     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.18.10816     Document Type: Article

References (22)

1. Sitkovsky, M. V., and Henkart, P. A. (1993) Cytotoxic Cells, Birkhaeuser Boston, Cambridge, MA
2. Berk, G. (1995) Cell 81, 9-12
3. Heusel, J. W., Wesselschmidt, R. L., Shresta, S., Russell, J. H., and Ley, T. J. (1994) Cell 76, 977-987
4. Darmon, A. J., Nicholson, D. W., and Bleackley, R. C. (1995) Nature 377, 446-448
5. Nicholson, D. W., Ali, A., Thornberry, N. A., Vaillancourt, J. P., Ding, C. K., Gallant, M., Gareau, Y., Griffin, P. R., Labelle, M., Lazebnik, Y. A., Munday, N. A., Raju, S. M., Smulson, M. E., Yamin, T.-T., Yu, V. L., and Miller, D. K. (1995) Nature 376, 37-43
6. Kaufmann, S. H., Desnoyers, S., Ottaviano, Y., Davidson, N. E., and Poirier, G. G. (1993) Cancer Res. 53, 3976-3985
7. Martin, S. J., and Green, D. R. (1995) Cell 82, 349-352
8. Yuan, J., Shaham, S., Ledoux, S., Ellis, H. M., and Horvitz, H. R. (1993) Cell 75, 641-652
9. Gagliardini, V., Fernandez, P. A., Lee, R. K., Drexier, H. C., Rotello, R. J., Fishman, M. C., and Yuan, J. (1994) Science 263, 826-828
10. Milligan, C. E., Prevette, D., Yaginuma, H., Homma, S., Cardwell, C., Fritz, L. C., Tomaselli, K.J., Oppenheim, R. W., and Schwartz, L. M. (1995) Neuron 15, 385-393
11. Kuida, K., Lippke, J. A., Ku, G., Harding, M. W., Livingston, D. J., Su, M. S.-S., and Flavell, R. A. (1995) Science 267, 2000-2003
12. Kumar S. (1995) Trends Biochem. Sci. 20, 198-202
13. Lippke, J. A., Gu, Y., Sarnecki, C., Caron, P. R., and Su, M. S.-S. (1996) J. Biol. Chem. 271, 1825-1828
14. Fernandes-Alnemri, T., Takahashi, A., Armstrong, R., Krebs, J., Fritz, L., Tomaselli, K., Wang, L., Yu, Z., Croce, C. M., Salveson, G., Earnshaw, W. C., Litwack, G., and Alnemri, E. S. (1995) Cancer Res. 55, 6045-6052
15. Duan, H., Chinnaiyan, A. M., Hudson, P. L., Wing, J. P., He, W.-W., and Dixit, V. M. (1996) J. Biol. Chem. 271, 1621-1625
16. Caputo, A., Garner, R. S., Winkler, U., Hudig, D., and Bleackley, R. C. (1993) J. Biol. Chem. 268, 17672-17675
17. Takebe, Y., Seiki, M., Fujisawa, J., Hoy, P., Yokota, K., Arai, K., Yoshida, M., and Arai, N. (1988) Mol. Cell. Biol. 8, 466-472
18. Gu, Y., Wu, J., Faucheu, C., Lalanne, J.-L., Diu, A., Livingston, D. J., and Su, M. S.-S. (1995) EMBO J. 14, 1923-1931
19. Hanna, W. L., Zhang, X., Turbov, J., Winkler, U., Hudig, D., and Froelicj, C. J. (1993) Protein Expression Purif. 4, 394-404
20. Kunkel, T. A. (1985) Proc. Natl. Acad. Sci. U. S. A. 82, 488-492
21. Gu, Y., Sarnecki, C., Aldape, R. A., Livingston, D. J., and Su, M. S.-S. (1995b) J. Biol. Chem. 270, 18715-18718
22. Thornberry, N. A., Bull, H. G.., Calaycay, J. R., Chapman, K. T., Howard, A. D., Kostura, M. J., Miller, D. K., Molineaux, S. M., Weidner, J. R., Aunins, J., Elliston, K. O., Ayala, J. M., Casano, F. J., Chin, J., Ding, G. J.-F., Egger, L. A., Gaffney, E. P., Limjuco, G., Palyha, O. C., Faju, S. M., Rolando, A. M., Salley, J. P., Yamin, T.-T., Lee, T. D., Shively, J. E., MacCross, M., Mumford, R. A., Schmidt, J. A., and Tocci, M. J. (1992) Nature 356, 768-774