Amino acid permeases require COPII components and the ER resident membrane protein Shr3p for packaging into transport vesicles in vitro

Journal of Cell Biology

Volumn 135, Issue 3, 1996, Pages 585-595

  Kuehn, Meta J ^a   Schekman, Randy ^a   Ljungdahl, Per O ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b LUDWIG INSTITUTE FOR CANCER RESEARCH   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; AMINO ACID; CHAPERONE; HISTIDINE; MEMBRANE PROTEIN; PERMEASE; PHEROMONE; SECRETORY PROTEIN;

ARTICLE; CELL MEMBRANE TRANSPORT; CYTOSOL; ENDOPLASMIC RETICULUM; ENZYME RELEASE; GOLGI COMPLEX; MEMBRANE VESICLE; MICROSOME; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; SACCHAROMYCES CEREVISIAE; SPHEROPLAST; YEAST;

AMINO ACID TRANSPORT SYSTEMS; AMINO ACID TRANSPORT SYSTEMS, BASIC; ATP-BINDING CASSETTE TRANSPORTERS; BACTERIAL PROTEINS; BIOLOGICAL TRANSPORT, ACTIVE; ENDOPLASMIC RETICULUM; FUNGAL PROTEINS; GOLGI APPARATUS; GTP-BINDING PROTEINS; INTRACELLULAR MEMBRANES; MEMBRANE PROTEINS; MEMBRANE TRANSPORT PROTEINS; MICROSOMES; MONOMERIC GTP-BINDING PROTEINS; NUCLEAR PORE COMPLEX PROTEINS; PEPTIDES; PROTEIN PRECURSORS; PROTON-TRANSLOCATING ATPASES; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SPHEROPLASTS;

SACCHAROMYCES CEREVISIAE;

EID: 0029831539     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.135.3.585     Document Type: Article

References (59)

1. Alani, E., L. Cao, and N. Kleckner. 1987. A method for gene disruption that allows repeated use of URA3 selection in the construction of multiply disrupted yeast strains. Genetics. 116:541-545.
2. Allen J.B., and S.J. Elledge. 1994. A family of vectors that facilitate transposon and insertional mutagenesis of cloned genes in yeast. Yeast. 10:1267-1272.
3. Andre, B. 1995. An overview of membrane transport proteins in Saccharomyces cerevisiae. Yeast. 11:1575-1611.
4. +2-ATPase homologue, PMR1, is required for normal Golgi function and localizes in a novel Golgi-like distribution. Mol. Biol. Cell. 3:633-654.
5. Baker, D., L. Hicke, M. Rexach, M. Schleyer, and R. Schekman. 1988. Reconstitution of SEC gene product-dependent intercompartmental protein transport. Cell. 54:335-344.
6. Baker, E.K., N.J. Colley, and C.S. Zuker. 1994. The cyclophilin homolog NinaA functions as a chaperone, forming a stable complex in vivo with its protein target rhodopsin. EMBO (Eur. Mol. Biol. Organ.) J. 13:4886-4895.
7. Barlowe, C., L. Orci, T. Yeung, M. Hosobuchi, S. Hamamoto, N. Salama, M.F. Rexach, M. Ravazzola, M. Amherdt, and R. Schekman. 1994. COPII: a membrane coat formed by Sec proteins that drive vesicle budding from the endoplasmic reticulum. Cell. 77:895-907.
8. Bednarek, S.Y., M. Ravazzola, M. Hosobuchi, M. Amherdt, A. Perrelet, R. Schekman, and L. Orci. 1995. COPI- and COPII-coated vesicles bud directly from the endoplasmic reticulum in yeast. Cell. 83:1183-1196.
9. Boeke, J.D., F. Lacroute, and G.R. Fink. 1984. A positive selection for mutants lacking orotidine 5′-phosphate decarboxylase activity in yeast: 5-fluoroorotic acid resistance. Mol. Gen. Genet. 181:288-291.
10. Brada, D., and R. Schekman. 1988. Coincident localization of secretory and plasma membrane proteins in organelles of the yeast secretory pathway. J. Bacteriol. 170:2775-2783.
11. Bu, G., H.J. Geuze, G.J. Strous, and A.L. Schwartz. 1995. 39 kDa receptor-associated protein is an ER resident protein and molecular chaperone for LDL receptor-related protein. EMBO (Eur. Mol. Biol. Organ.) J. 14:2269-2280.
12. Chang, A., and C.W. Slayman. 1991. Maturation of the yeast plasma membrane [H+]ATPase involves phosphorylation during intracellular transport. J. Cell Biol. 115:289-295.
13. Chang, A., and G.R. Fink. 1995. Targeting of the yeast plasma membrane [H+]ATPase: a novel gene AST1 prevents mislocalization of mutant ATPase to the vacuole. J. Cell Biol. 128:39-49.
14. Chapman, R.E., and S. Munro. 1994. The functioning of the yeast Golgi apparatus requires an ER protein encoded by ANP1, a member of a new family of genes affecting the secretory pathway. EMBO (Eur. Mol. Biol. Organ.) J. 13: 4896-4907.
15. Colley, N.J., E.K. Baker, M.A. Stamnes, and C.S. Zuker. 1991. The cyclophilin homolog ninaA is required in the secretory pathway. Cell. 67:255-263.
16. Courchesne, W.E., and B. Magasanik. 1983. Ammonia regulation of amino acid permeases in Saccharomyces cerevisiae. Mol. Cell. Biol. 3:672-683.
17. de Kerchove d'Exaerde, A., P. Supply, J.P. Dufour, P. Bogaerts, D. Thines, A. Goffeau, and M. Boutry. 1995. Functional complementation of a null mutation of the yeast Saccharomyces cerevisiae plasma membrane H(+)-ATPase by a plant H(+)-ATPase gene. J. Biol. Chem. 270:23828-23837.
18. Doering, T.L., and R. Schekman. 1996. GPI anchor attachment is required for Gas1p transport from the endoplasmic reticulum in COP II vesicles. EMBO (Eur. Mol. Biol. Organ.) J. 15:182-191.
19. Espenshade, P., R.E. Gimeno, E. Holzmacher, P. Teung, and C.A. Kaiser. 1995. Yeast SEC16 gene encodes a multidomain vesicle coat protein that interacts with Sec23p. J. Cell Biol. 131:311-324.
20. Evan, G.I., G.K. Lewis, G. Ramsay, and J.M. Bishop. 1985. Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product. Mol. Cell. Biol. 5:3610-3616.
21. Gething, M.J., and J. Sambrook. 1992. Protein folding in the cell. Nature (Lond.). 355:33-45.
22. Green, N., H. Fang, and P. Walter. 1992. Mutants in three novel complementation groups inhibit membrane protein insertion into and soluble protein translocation across the endoplasmic reticulum membrane of Saccharomyces cerevisiae. J. Cell Biol. 116:597-604.
23. Guthrie, C., and G.R. Fink. 1991. Guide to yeast genetics and molecular biology. Methods Enzymol. 194:186-187.
24. Hammond, C., and A. Helenius. 1995. Quality control in the secretory pathway. Curr. Opin. Cell Biol. 7:523-529.
25. Harris, S.L., S. Na, X. Zhu, D. Seto-Young, D.S. Perlin, J.H. Teem, and J.E. Haber. 1994. Dominant lethal mutations in the plasma membrane H(+)-ATPase gene of Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA. 91: 10531-10535.
26. Harsay, E., and A. Bretscher. 1995. Parallel secretory pathways to the cell surface in yeast. J. Cell Biol. 131:297-310.
27. Hill, K.J., and T.H. Stevens. 1994. Vma21p is a yeast membrane protein retained in the endoplasmic reticulum by a di-lysine motif and is required for the assembly of the vacuolar H(+)-ATPase complex. Mol. Biol. Cell. 5: 1039-1050.
28. Hirata, R., N. Umemoto, M.N. Ho, Y. Ohya, T.H. Stevens, and Y. Anraku. 1993. VMA12 is essential for assembly of the vacuolar H(+)-ATPase subunits onto the vacuolar membrane in Saccharomyces cerevisiae. J. Biol. Chem. 268:961-967.
29. Holcomb, C.L., W.J. Hansen, T. Etcheverry, and R. Schekman. 1988. Secretory vesicles externalize the major plasma membrane ATPase in yeast. J. Cell Biol. 106:641-648.
30. Kolodziej, P.A. and R.A. Young. 1991. Epitope tagging and protein surveillance. Methods Enzymol. 194:508-519.
31. Kunkel, T.A., J.D. Roberts and R.A. Zakour. 1987. Rapid and efficient site-specific mutagenesis without phenotypic selection. Methods Enzymol. 154: 367-382.
32. Lian, J.P., and S. Ferro-Novick. 1993. Bos1p, an integral membrane protein of the endoplasmic reticulum to Golgi transport vesicles, is required for their fusion competence. Cell. 73:735-745.
33. Ljungdahl, P.O., C.J. Gimeno, C.A. Styles, and G.R. Fink. 1992. SHR3: a novel component of the secretory pathway specifically required for localization of amino acid permeases in yeast. Cell. 71:463-478.
34. Ma, H., S. Kunes, P.J. Schatz, and D. Botstein. 1987. Plasmid construction by homologous recombination in yeast. Gene (Amst.). 58:201-216.
35. Palade, G. 1975. Intracellular aspects of the process of protein secretion. Science (Wash. DC). 189:347-358.
36. Pryer, N.K., L.J. Wuestehube, and R. Schekman. 1992. Vesicle mediated protein sorting. Annu. Rev. Biochem. 61:471-516.
37. Rexach, M., and R.W. Schekman. 1991. Distinct biochemical requirements for the budding, targeting, and fusion of ER-derived transport vesicles. J. Cell Biol. 114:219-229.
38. Rexach, M.F., M. Latterich, and R. Schekman. 1994. Characteristics of endoplasmic reticulum-derived transport vesicles. J. Cell Biol. 126:1133-1148.
39. Rothman, J.E. 1994. Mechanisms of intracellular protein transport. Nature (Lond.). 372:55-63.
40. Salama, N.R., T. Yeung, and R.W. Schekman. 1993. The Sec13p complex and reconstitution of vesicle budding from the ER with purified cytosolic proteins. EMBO (Eur. Mol. Biol. Organ.) J. 12:4073-4082.
41. Sanz, P., E. Herrero, and R. Sentandreu. 1987. Secretory pattern of a major integral mannoprotein of the yeast cell wall. Biochim. Biophys. Acta. 924:193-203.
42. Schekman, R. 1992. Genetic and biochemical analysis of vesicular traffic in yeast. Curr. Opin. Cell Biol. 4:587-592.
43. Schekman, R., and L. Orci. 1996. Coat proteins and vesicle budding. Science (Wash. DC). 271:1526-1533.
44. Schimmoller, F., B. Singer-Kruger, S. Schroder, U. Kruger, C. Barlowe, and H. Riezman. 1995. The absence of Emp24p, a component of ER derived COPII-coated vesicles, causes a defect in transport of selected proteins to the Golgi. EMBO (Eur. Mol. Biol. Oragn.) J. 14:1329-1339.
45. Schmidt, A., M.N. Hall, and A. Koller. 1994. Two FK506 resistance-conferring genes in Saccharomyces cerevisiae, TAT1 and TAT2, encode amino acid permeases mediating tyrosine and tryptophan uptake. Mol. Cell. Biol. 14:6597-6606.
46. Serrano, R. 1989. Structure and function of plasma membrane ATPase. Annu. Rev. Plant Physiol. Plant Mol. Biol. 40:61-94.
47. 2+-ATPases. Nature (Lond.). 319:689-693.
48. Sikorski, R.S., and P. Hieter. 1989. A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics. 122:19-27.
49. Stevenson, B.J., B. Ferguson, C. De Virgilio, E. Bi, J.R. Pringle, G. Ammerer, and G.F. Sprague Jr. 1995. Mutation of RGA1, which encodes a putative GTPase-activating protein for polarity-establishment protein Cdc42p, activates the pheromone-response pathway in the yeast Saccharomyces cerevisiae. Genes Dev. 9:2949-2963.
50. Stirling, C.J., J. Rothblatt, M. Hosobuchi, R. Deshaies, and R. Schekman. 1992. Protein translocation mutants defective in the insertion of integral membrane proteins into the endoplasmic reticulum. Mol. Biol. Cell. 3:129-142.
51. Stotz, A. and P. Linder. 1990. The ADE2 gene from Saccharomyces cerevisiae: sequence and new vectors. Gene (Amst.). 95:91-98.
52. Tanaka, J., and G.R. Fink. 1985. The histidine permease gene (HIPI) of Saccharomyces cerevisiae. Gene (Amst.). 38:205-214.
53. Vieira, J., and J. Messing. 1987. Production of single-stranded plasmid DNA. Methods Enzymol. 153:3-11.
54. Villalba, J.M., M.G. Palmgren, G.E. Berberian, C. Ferguson, and R. Serrano. 1992. Functional expression of plant plasma membrane H(+)-ATPase in yeast endoplasmic reticulum. J. Biol. Chem. 267:12341-12349.
55. Walworth, N.C., and P.J. Novick. 1987. Purification and characterization of constitutive secretory vesicles from yeast. J. Cell Biol. 105:163-174.
56. Wilson, I.A., H.L. Niman, R.A. Houghton, A.R. Cherenson, M.L. Connolly, and R.A. Lerner. 1984. The structure of an antigenic determinant in a protein. Cell. 37:767-778.
57. Wuestehube, L.J., and R. Schekman. 1992. Reconstitution of transport from the endoplasmic reticulum to the Golgi complex using an ER-enriched membrane fraction from yeast. Methods Enzymol. 219:124-136.
58. Yeung, T., C. Barlowe, and R. Schekman. 1995. Uncoupled packaging of targeting and cargo molecules during transport vesicle budding from the endoplasmic reticulum. J. Biol. Chem. 270:30567-30570.
59. Ziman, M., J. Chuang, and R. Schekman. 1996. Chs1p and Chs3p, two proteins involved in chitin synthesis, populate a compartment of the Saccharomyces cerevisiae endocytic pathway. Mol. Biol. Cell. In press.