Identification and mapping of human cDNAs homologous to Drosophila mutant genes through EST database searching

Nature Genetics

Volumn 13, Issue 2, 1996, Pages 167-174

  Banfi, Sandro ^a   Borsani, Giuseppe ^a   Rossi, Elena ^b,c   Bernard, Loris ^a   Guffanti, Alessandro ^a   Rubboli, Francesca ^a   Marchitiello, Anna ^a   Giglio, Sabrina ^c   Coluccia, Elisabetta ^c   Zollo, Massimo ^a   Zuffardi, Orsetta ^b,c   Ballabio, Andrea ^a,d  

^a TELETHON INSTITUTE OF GENETICS AND MEDICINE TIGEM   (Italy)

^b Servizio di Citogenetica   (Italy)

^c UNIVERSITY OF PAVIA   (Italy)

^d UNIVERSITY OF SIENA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA;

ARTICLE; DATA BASE; DROSOPHILA; GENE MAPPING; GENE SEQUENCE; GENETIC DISORDER; GENETIC TRANSCRIPTION; HUMAN; PRIORITY JOURNAL; SEQUENCE HOMOLOGY;

MAMMALIA;

EID: 9044223283     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/ng0696-167     Document Type: Article

References (48)

1. Patel, P.I. et al. The gene for the peripheral myelin protein PMP-22 is a candidate for Charcot-Marie-Tooth disease type 1A. Nature Genet. 1, 159-165 (1992).
2. Tugendreich, S., Boguski, M.S., Seldin, M.S. & Hieter, P. Linking yeast genetics to mammalian genomes: Identification and mapping of the human homolog of CDC27 via the expressed sequence tag (EST) data base. Proc. Natl. Acad. Sci. USA 90, 10031-10035 (1993).
3. Bronner, C.E. et al. Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer. Nature 368, 258-260 (1994).
4. Sargent, C.A. et al. Cloning of the X-linked glycerol kinase deficiency gene and its identification by sequence comparison to the Bacillus subtilis homologue. Hum. Mol. Genet. 2, 97-106 (1993).
5. Bassett, D.E., Jr., Boguski, M.S. & Hieter, P. Yeast genes and human disease. Nature 379, 589-590 (1996).
6. Rubin, G.M. Drosophila melanogaster as an experimental organism. Science 240, 1453-1459 (1988).
7. Lindsley, D.L. & Zimm, G.G. in The Genome of Drosophila Melanogaster (Academic Press, San Diego, 1992).
8. The FlyBase Consortium. FlyBase-the Drosophila database. Nucl. Acids Res. 22, 3456-3458 (1994).
9. Bellen, H.J. & Smith, R.F. FlyBase: a virtual Drosophila cornucopia. Trends Genet. 11, 456-457 (1995).
10. Mounkes, L.C., Jones, R.S., Liang, B.-C., Gelbart, W. & Fuller, M.T. A drosophila model for xeroderma pigmentosum and Cockayne's syndrome: haywire encodes the fly homolog of ERCC3, a human excision repair gene. Cell 71, 925-937 (1992).
11. Quiring, R., Walldorf, U., Kloter, U. & Gehring, W.J. Homology of the eyeless gene of Drosophila to the small eye gene in mice and Aniridia in humans. Science 265, 785-789 (1994).
12. Merriam, J., Ashburner, M., Hartl, D.L. & Kafatos, F.C. Toward cloning and mapping the genome of Drosophila. Science 254, 221-225 (1991).
13. Green, E.D., Cox, D.R. & Myers, R.M. in Tne Metabolic and Molecular Bases of Inherited Disease (eds. Scriver, C.R., Beaudet, A.L., Sly, W.S. & Valle, D.) 401-436 (McGraw-Hill, New York, 1995).
14. Guyer, M.S. & Collins, F.S. How is the Human Genome Project doing, and what have we learned so far? Proc. Natl. Acad. Sci. USA 92, 10841-10848 (1995).
15. Adams, M.D. et al. Complementary DNA sequencing: expressed sequence tags and human genome project. Science 252, 1651-1656 (1991).
16. Adams, M.D. et al. Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence. Nature 377, 3-17 (1995).
17. Lennon, G.G., Auffray, C., Polymeropoulos, M. & Soares, M.B. The IMAGE Consortium: an integrated molecular analysis of genomes and their expression. Genomics (in the press).
18. Boguski, M.S., Lowe, T.M.J. & Tolstoshev, C.M. dbEST - database for "expressed sequence tags". Nature Genet. 4, 332-333 (1993).
19. Polymeropoulos, M.H. et al. Chromosomal distribution of 320 genes from a brain cDNA library. Nature Genet. 4, 381-386 (1993).
20. Korenberg, J.R., Chen, X.-N., Adams, M.D. & Venter, J.C. Toward a cDNA map of the human genome. Genomics 29, 364-370 (1995).
21. Hudson, T.J. et al. An STS-based map of the human genome. Science 270, 1945-1954 (1995).
22. Berry, R. et al. Gene-based sequence-tagged-sites (STSs) as the basis for a human gene map. Nature Genet. 10, 415-423 (1995).
23. Ballabio, A. The rise and fall of positional cloning? Nature Genet. 3, 277-279 (1993).
24. Altschul, S.F., Gish, W., Miller, W., Myers, E.W. & Lipman, D.J. Basic local alignment search tool. J. Mol. Biol. 215, 403-410 (1990).
25. Soares, M.B. et al. Construction and characterization of a normalized cDNA library. Proc. Natl. Acad. Sci. USA 91, 9228-9232 (1994).
26. Hahn, SA et al. DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1. Science 271, 350-353 (1995).
27. Wes, P.D. et al. TRPC1, a human homolog of a Drosophila store-operated channel. Proc. Natl. Acad. Sci. USA 92, 9652-9656 (1995).
28. Creasy, C.L. & Chernoff, J. Cloning and characterization of a human protein kinase with homology to Ste20. J. Biol. Chem. 270, 21695-21700 (1995).
29. Boguski, M.S. & Schuler, G.D. ESTablishing a human transcript map. Nature Genet. 10, 369-373 (1995).
30. Aruga, J. et al. A novel zinc finger protein, zic, is involved in neurogenesis, especially in the cell lineage of cerebellar granule cells. J. Neurochem. 63, 1880-1890 (1994).
31. Lindsell, C.E., Shawber, C.J., Boulter, J. & Weinmaster, G. Jagged: a mammalian ligand that activates Notch1. Cell 80, 909-917 (1995).
32. Simeone, A. et al. Two vertebrate homeobox genes related to the Drosophila empty spiracles gene are expressed in the embryonic cerebral cortex. EMBO J. 11, 2541-2550 (1992).
33. Cox, D.R., Burmeister, M., Price, E.R., Kim, S. & Myers, R.M. Radiation hybrid mapping: a somatic cell genetic method for constructing high-resolution maps of mammalian chromosomes. Science 250, 245-250 (1990).
34. Walter, M.A., Spillett, D.J., Thomas, P., Weissenbach, J. & Goodfellow, P.N. A method for constructing radiation hybrid maps of whole genomes. Nature Genet. 7, 22-28 (1994).
35. McGinnis, W. & Krumlauf, R. Homeobox genes and axial patterning. Cell 68, 283-302 (1992).
36. Collins, F.S. Positional cloning moves from perditional to traditional. Nature Genet. 9, 347-350 (1995).
37. Stone, E.M. et al. Genetic linkage of autosomal dominant neovascular inflammatory vitreoretinopathy to chromosome 11q13. Hum. Mol. Genet. 1, 685-689 (1992).
38. Graff, C. et al. Fine mapping of Best's macular dystrophy localizes the gene in close proximity to but distinct from the D11S480/ROM1 loci. Genomes 24, 425-434 (1994).
39. Leppert, M. et al. Bardet-Biedl syndrome is linked to DNA markers on chromosome 11q and is genetically heterogeneous. Nature Genet. 7, 108-112 (1994).
40. Spence, S.E. et al. Genetic localization of Hao-1, blind-sterile (bs), and Emv-13 on mouse chromosome 2. Genomics 12, 403-404 (1992).
41. Dahmane, N. et al. Down syndrome-critical region contains a gene homologous to Drosophila sim expressed during rat and human central nervous system development. Proc. Natl. Acad. Sci. USA 92, 9191-9195 (1995).
42. Chen, H.M., Rossier, C. & Antonarakis, S.E. Identification of human homologs of the drosophila White [W] and enhancer of zeste [E(z)] loci and mapping to human chromosome 21. Am J. Hum. Genet. 57, A40 (1995).
43. Wootton, J.C. & Federhen, S. Statistics of local complexity in amino acid sequences and sequence databases. Computers Chem. 17, 149-163 (1993).
44. Claverie, J.M. & States, D.J. Information enhancement methods for large scale sequence analysis. Computers Chem. 17, 191-201 (1993).
45. Huang, X. A contig assembly program based on sensitive detection of fragment overlaps. Genomics 14, 18-25 (1992).
46. Dutrillaux, B. & Viegas-Pequignot, E. High resolution R- and G-banding on the same preparation. Hum. Genet. 57, 93-95 (1981).
47. Chumakov, I.M. et al. A YAC contig map of the human genome. Nature 377, 175-183 (1995).
48. Smith, R.F. & Smith, T.F. Pattern-induced multi-sequence allignment (PIMA) algorithm employing secondary structure-dependent gap penalties for use in comparative protein modelling. Protein Engng. 5, 35-41 (1992).