Extracellular nucleotides act through P(2U) purinoceptors to elevate [Ca2+](i) and enhance basic fibroblast growth factor-induced proliferation in sheep chondrocytes

Endocrinology

Volumn 137, Issue 11, 1996, Pages 4757-4766

  Kaplan, Andrew D ^a   Kilkenny, Dawn M ^a,b   Hill, David J ^a,b   Dixon, S Jeffrey ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

^b LAWSON HEALTH RESEARCH INSTITUTE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

2 METHYLTHIOADENOSINE TRIPHOSPHATE; 4ALPHA PHORBOL DIDECANOATE; ADENOSINE; ADENOSINE DIPHOSPHATE; ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; BASIC FIBROBLAST GROWTH FACTOR; BRADYKININ; CALCIUM ION; CELL SURFACE RECEPTOR; DNA; GUANINE NUCLEOTIDE BINDING PROTEIN; INDO 1; LYSOPHOSPHATIDIC ACID; NUCLEOTIDE; PERTUSSIS TOXIN; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C; PURINE P2 RECEPTOR; PURINERGIC RECEPTOR STIMULATING AGENT; PYROPHOSPHATE; RECEPTOR SUBTYPE; SURAMIN; THAPSIGARGIN; URIDINE TRIPHOSPHATE;

ANIMAL CELL; ARTICLE; CARTILAGE CELL; CELL PROLIFERATION; CONTROLLED STUDY; DNA SYNTHESIS; FETUS; NONHUMAN; PRIORITY JOURNAL; SHEEP; SPECTROFLUOROMETRY;

EID: 0029824778     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.137.11.8895344     Document Type: Article

References (52)

1. Fredholm BB, Abbracchio MP, Burnstock G, Daly JW, Harden TK, Jacobson KA, Leff P, Williams M 1994 Nomenclature and classification of purinoceptors. Pharmacol Rev 46:143-156
2. 2-purinergic receptors: subtype-associated signaling responses and structure. Annu Rev Pharmacol Toxicol 35:541-579
3. Burnstock G 1978 A basis for distinguishing two types of purinergic receptors In: Straub RW, Bolis L (eds) Cell Membrane Receptors for Drugs and Hormones. Raven Press, New York, pp 107-118
4. 6 receptors and the distribution and properties of an extended family of ATP-gated ion channels. J Neurosci 16:2495-2507
5. i, in rat osteoblastic cells by interaction with two receptor subtypes. Am J Physiol 263:C1040-C1048
6. 2U purinergic receptors with similar second messenger signaling pathways in UMR-106 osteoblasts. J Pharmacol Exp Ther 269:1049-1061
7. 2-purinoceptors at the surface of human articular chondrocytes in monolayer culture. Biochim Biophys Acta 1074:151-158
8. 2-purinoceptors. Biochim Biophys Acta 1201:298-304
9. Boskey AL, Doty SB, Binderman I 1994 Adenosine 5′-triphosphate promotes mineralization in differentiating chick limb-bud mesenchymal cell cultures. Microsc Res Technol 28:492-504
10. Hatori M, Teixeira CC, Debolt K, Pacifici M, Shapiro IM 1995 Adenine nucleotide metabolism by chondrocytes in vitro: role of ATP in chondrocyte maturation and matrix mineralization. J Cell Physiol 165:468-474
11. Evans RJ, Derkach V, Surprenant A 1992 ATP mediates fast synaptic transmission in mammalian neurons. Nature 357:503-505
12. Huang N, Wang D, Heppel LA 1989 Extracellular ATP is a mitogen for 3T3, 3T6 and A431 cells and acts synergistically with other growth factors. Proc Natl Acad Sci USA 86:7904-7908
13. Huwiler A, Pfeilschifter J 1994 Stimulation by extracellular ATP and UTP of the mitogen-activated protein kinase cascade and proliferation of rat renal mesangial cells. Br J Pharmacol 113:1455-1463
14. Neary JT, Whittemore SR, Zhu Q, Norenberg MD 1994 Synergistic activation of DNA synthesis in astrocytes by fibroblast growth factors and extracellular ATP. J Neurochem 63:490-494
15. Zheng LM, Zychlinsky A, Liu CC, Ojcius DM, Young JDE 1991 Extracellular ATP as a trigger for apoptosis or programmed cell death. J Cell Biol 112:279-288
16. Osipchuk Y, Cahalan M 1992 Cell-to-cell spread of calcium signals mediated by ATP receptors in mast cells. Nature 359:241-244
17. Born GVR, Kratzer MAA 1984 Source and concentration of extracellular adenosine triphosphate during haemostasis in rats, rabbits and man. J Physiol (Lond) 354:419-429
18. Hill DJ, De Sousa D 1990 Insulin is a mitogen for isolated epiphyseal growth plate chondrocytes from the fetal lamb. Endocrinology 126:2661-2670
19. Hill DJ, Logan A 1992 Interactions of peptide growth factors during DNA synthesis in isolated ovine fetal growth plate chondrocytes. Growth Regul 2:122-132
20. 1. J Endocrinol 133:363-373
21. 2+ indicators with greatly improved fluorescence properties. J Biol Chem 260:3440-3450
22. 2+ in platelets and neutrophils. Biochem J 269:513-519
23. 2-purinergic receptors for extracellular ATP and other nucleotides. Am J Physiol 265:C577-C606
24. Benton HP, Jackson TR, Hanley MR 1989 Identification of a novel inflammatory stimulant of chondrocytes. Biochem J 258:861-867
25. Moolenaar WH, Jalink K, van Corven EJ 1992 Lysophosphatidic acid: a bioactive phospholipid with growth factor-like properties. Rev Physiol Biochem Pharmacol 119:47-65
26. 2U signaling pathways. J Cell Physiol 162:305-314
27. Kumagai H, Sacktor B, Filburn CR 1991 Purinergic regulation of cytosolic calcium and phosphoinositide metabolism in rat osteoblast-like osteosarcoma cells. J Bone Miner Res 6:697-708
28. Cockcroft S, Stutchfield J 1989 ATP stimulates secretion in human neutrophils and HL60 cells via a pertussis toxin-sensitive guanine nucleotide-binding protein coupled to phospholipase C. FEBS Lett 245:25-29
29. Davidson JS, Wakefield IK, Sohnius U, van der Merwe PA, Millar RP 1990 A novel extracellular nucleotide receptor coupled to phosphoinositidase-C in pituitary cells. Endocrinology 126:80-87
30. 2U purinergic receptor. Proc Natl Acad Sci USA 90:10449-10453
31. 2+, but not cyclic adenosine 3′,5′-monophosphate response to parathyroid hormone in rat osteoblastic cells. Endocrinology 136:1674-1685
32. 2Y purinergic receptor that couples to phospholipase C. Mol Pharmacol 46:8-14
33. Lustig KD, Shiau AK, Brake AJ, Julius D 1993 Expression cloning of an ATP receptor from mouse neuroblastoma cells. Proc Natl Acad Sci USA 90:5113-5117
34. 2U purinoceptor present in osteoclastoma, bone, and osteoblasts. J Bone Miner Res 10:1137-1145
35. 1 MF-2 vas deferens cells. Eur J Pharmacol 215:317-320
36. 2Y-purinoceptors and nucleotide receptors linked to phospholipase C. Br J Pharmacol 108:689-693
37. 2+-ATPase. Proc Natl Acad Sci USA 87:2466-2470
38. 2u-purinergic receptor. Am J Respir Cell Mol Biol 12:27-32
39. 2U nucleotide receptor, a target for cystic fibrosis pharmacotherapy. Proc Natl Acad Sci USA 91:3275-3279
40. 2-purinergic receptors in human phagocytic leukocytes. Ann NY Acad Sci 603:227-245
41. Garritsen A, Zhang Y, Cooper DMF 1992 Purinergic receptor regulation of signal transduction in NCB-20 cells. Mol Pharmacol 41:743-749
42. Nishizuka Y 1992 Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C. Science 258:607-614
43. Kuroki M, Takeshige K, Minakami S 1989 ATP-induced calcium mobilization in human neutrophils. Biochim Biophys Acta 1012:103-106
44. Pfeilschifter J 1990 Comparison of extracellular ATP and UTP signalling in rat renal mesangial cells. Biochem J 272:469-472
45. 2U partially mediates ATP-induced cell cycle progression of aortic smooth muscle cells. J Cell Physiol 166:57-65
46. Olwin BB, Hauschka SD 1986 Identification of the fibroblast growth factor receptor of Swiss 3T3 cells and mouse skeletal muscle myoblasts. Biochemistry 25:3487-3492
47. Clapham DE 1995 Calcium signaling. Cell 80:259-268
48. van Biesen T, Hawes BE, Luttrell DK, Krueger KM, Touhara K, Porfiri E, Sakaue M, Luttrell LM, Lefkowitz RJ 1995 Receptor-tyrosine-kinase- and Gβγ-mediated MAP kinase activation by a common signalling pathway. Nature 376:781-784
49. Al-Awqati Q 1995 Regulation of ion channels by ABC transporters that secrete ATP. Science 269:805-806
50. Mangham DC, Cannon A, Komiya S, Gendron RL, Dunussi K, Gebhardt MC, Mankin HJ, Arceci RJ 1996 P-Glycoprotein is expressed in the mineralizing regions of the skeleton. Calcif Tissue Int 58:186-191
51. Abraham EH, Prat AG, Gerweck L, Seneveratne T, Arceci RJ, Kramer R, Guidotti G, Cantiello HF 1993 The multidrug resistance (mdr1) gene product functions as an ATP channel. Proc Natl Acad Sci USA 90:312-316
52. 2+ waves in ATP-stimulated articular chondrocytes. J Bone Miner Res 11:946-954