Mutations in the yeast SRB2 general transcription factor suppress hpr1- induced recombination and show defects in DNA repair

Genetics

Volumn 143, Issue 4, 1996, Pages 1533-1542

  Piruat, José I ^a   Aguilera, Andrés ^a  

^a UNIVERSITY OF SEVILLE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; TRANSCRIPTION FACTOR;

CONTROLLED STUDY; DNA RECOMBINATION; DNA REPAIR; DNA SEQUENCE; GENE DELETION; NONHUMAN; PRIORITY JOURNAL; REVIEW; YEAST;

ALLELES; DNA REPAIR; DRUG RESISTANCE, MICROBIAL; FUNGAL PROTEINS; GENES, FUNGAL; METHYL METHANESULFONATE; MUTAGENS; MUTATION; PHENOTYPE; POINT MUTATION; RECOMBINATION, GENETIC; REPETITIVE SEQUENCES, NUCLEIC ACID; RESTRICTION MAPPING; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE DELETION; TRANSCRIPTION FACTORS;

EID: 0029820765     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (68)

1. ABOUSSEKHRA, A., and R. D. WOOD, 1994 Repair of UV-damaged DNA by mammalian cells and Saccharomyces cerevisiae. Curr. Opin. Genet. Dev. 4: 212-220.
2. AGUILERA, A., 1995 Gentic evidence for different RAD52-dependent intrachromosomal recombination pathways in Saccharomyces cerevisiae. Curr. Genet. 25: 298-305.
3. AGUILERA, A., and H. L. KLEIN, 1989a Genetic and molecular analysis of recombination events in Saccharomyces cerevisiae occurring in the presence of the hyper-recombination mutation hpr1. Genetics 112: 503-517.
4. AGUILERA, A., and H. L. KLEIN, 1989b Yeast intrachromosomal recombination: long gene conversion tracts are preferentially associated with reciprocal exchange and require the RAD1 and RAD3 gene products. Genetics 123: 683-694.
5. AGUILERA, A., and H. L. KLEIN, 1990 HPR1, a novel yeast gene that prevents intrachromosomal excision recombination, shows carboxy-terminal homology to the Saccharomyces cerevisiae TOP1 gene. Mol. Cell. Biol. 10: 1439-1451.
6. 35S label as an aid to rapid DNA sequence determination. Proc. Natl. Acad. Sci. USA 80: 3963-3965.
7. BOURGAUX-RAMOISY, D., D. GENDRON and P. BOURGAUX, 1995 A hotspot for promoter-dependent recombination in polyomavirus DNA. J. Mol. Biol. 248: 220-224.
8. CHRISTMAN, M. F., F. S. DIETRICH and G. R. FINK, 1988 Mitotic recombination in the rDNA of S. cerevisiae is suppressed by the combined action of DNA topoisomerases I and II. Cell 55: 413-425.
9. CLARK, A. J., and K. B. LOW, 1988 Pathways and systems of general recombination in Escherichia coli, pp.155-215 in The Recombination of the Genetic Material, edited by K. B. LOW. Academic Press, New York.
10. CLEAVER, J. K., 1994 It was a very good year for DNA repair. Cell 76: 1-4.
11. CLEWELL, D., and D. HELINSKI, 1970 Properties of a supercoiled deoxyribonucleic acid-protein relaxation complex and strand specificity of the relaxation event. Biochemistry 9: 4428-4440.
12. DRAPKIN, R., A. SANCAR and D. REINBERG, 1994 Where transcription meets repair. Oil 77: 9-12.
13. DUL J. L., and H. DREXLER, 1988a Transcription stimulates recombination. I. Specialized transduction of Escherichia coli λtrp phages. Virology 162: 466-470.
14. DUL J. L, and H. DREXLER, 1988b Transcription stimulates recombination. II. Generalized transduction of Escherichia coli by phages T1 and T4. Virology 162: 471-477.
15. FAN, H.-Y., and H. L. KLEIN, 1994 Characterization of mutations that suppress the temperature-sensitive growth of the hpr1ΔA mutant of Saccharomyces cerevisiae. Genetics 137: 1-12.
16. FAN, H.-Y., K. K. CHENG and H. L. KLEIN, 1996 Mutations in the RNA polymerase II transcription machinery suppress the hyper-recombination mutant hpr1Δ of Saccharmomyces cerevisiae. Genetics 142: 749-759.
17. FEINBERG, A. P., and B. VOLGELSTEIN, 1984 A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem. 137: 266-267.
18. FISHMAN-LOBELL, J. and J. E. HABER, 1992 Removal of nonhomologous DNA ends in double-strand break recombination: the role of the yeast ultraviolet repair gene RAD1. Science 258: 480-484.
19. FUKUCHI, K., G. M. MARTIN and R. J. MONNAT, JR., 1989 Mutator phenotype of Werner syndrome is characterized by extensive deletions. Proc. Natl. Acad. Sci. USA 86: 5893-5897.
20. GOTTLIEB, S., J. WAGSTAFF and R. E. ESPOSITO, 1989 Evidence for two pathways of meiotic intrachromosomal recombination in yeast. Proc. Natl. Acad. Sci. USA 86: 7072-7076.
21. GUARENTE, L. R., 1983 Yeast promoters and LacZ, fusions designed to study expression of cloned genes in yeast. Methods Enzymol. 101: 181-191.
22. GUARENTE, L. R., R. YOCUM and P. GIFFORD. 1982 A GAL10-CYC1 hybrid yeast promoter identifies the GAL4 regulatory region as an upstream site. Proc. Natl. Acad. Sci. USA 79: 7410-7414.
23. HILL, J. E., A. M. MYERS, T. J. KOERNER and A. TZAGALOFF, 1986 Yeast/E. coli shuttle vectors with multiple unique restriction sites. Yeast 2: 163-167.
24. HOFFMAN, C. S., and F. WINSTON, 1987 A ten-minute DNA preparation from yeast efficiently releases autonomous plasmids for transformation of Escherichia coli. Gene 57: 267-272.
25. ITO, H., Y. FUKUDA, K. MURATA and A. KIMURA, 1983 Transformation of intact cells treated with alkali cations. J. Bacteriol. 153: 163-168.
26. IVANOV, E. L., and J. E. HABER, 1995 RAD1 and RAD10, but not other excision repair genes, are required for double-strand break-induced recombination in Saccharomyces cerevisiae. Mol. Cell. Biol. 15: 2245-2251.
27. JACKSON, J. A., and G. R. FINK, 1981 Gene conversion between duplicated genetics elements in yeast. Nature 292: 306-311.
28. KEIL, R. L., and A. D. MCWILLIANS, 1993 A gene with specific and global effects on recombination of sequences from tandemly repeated genes in Saccharomyces cerevisiae. Genetics 135: 711-718.
29. KEIL, R. L., and G. S. ROEDER, 1984 cis-acting, recombination-stimulating activity in a fragment of the ribosomal DNA of S. cerevisiae. Cell 57: 377-386.
30. KIM, Y.-J., S. BJORKLUND, L. Y. LI, M. SAYRE and R. KORNBERG, 1994 A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II. Cell 77: 599-608.
31. KLEIN, H. L., 1988 Different types of recombination events are controlled by the RAD1 and RAD52 genes of Saccharomyces cerevisiae. Genetics 120: 367-377.
32. KOLESKE, A. J., and R. A. YOUNG, 1994 An RNA polymerase II holoenzyme responsive to activators. Nature 368: 466-469.
33. KOLESKE, A. J., S. BURATOWSKI, M. NONET and R. A. YOUNG, 1992 A novel transcription factor reveals a functional link betwen the RNA polymerase II CTD and TFIID. Cell 69: 883-894.
34. KUZMINOV, A., 1995 Collapse and repair of replication forks in Escherichia call. Mol. Microbiol. 16: 373-384.
35. LIEFSHITZ, B., A. PARKET, R. MAYA and M. KUPIEC, 1995 The role of DNA repair genes in recombination between repeated sequences in yeast. Genetics 140: 1199-1211.
36. MCDONALD, J. P., and R. ROTHSTEIN, 1994 Unrepaired heteroduplex DNA in Saccharomyces cerevisiae is decreased in RAD1 RAD52-independent recombination. Genetics 137: 393-405.
37. MEAD, D. A., E. SZCZESNA-SKORUPA and B. KEMPER, 1986 Single-stranded DNA 'blue' T7 promoter plasmids: a versatile tandem promoter system for cloning and protein engineering. Protein Eng. 1: 67-74.
38. MEYN, M. S., 1993 High spontaneous intrachromosomal recombination rates in Ataxia-Telangiectasia. Science 260: 1327-1330.
39. MEZARD, C., and A. NICOLAS, 1994 Homologous, homeologous, and illegitimate repair of double-strand breaks during transformation of a wild-type strain and rad52 mutant strain of Saccharomyces cerevisiae. Mol. Cell. Biol. 14: 1278-1292.
40. NICKOLOFF, J. A., J. D. SINGER, M. F. HOEKSTRA and F. HEFFRON, 1989 Double-strand breaks stimulate alternative mechanisms of recombination repair. J. Mol. Biol. 27: 527-541.
41. NONET, M. L., and R. A. YOUNG, 1989 Intragenic and extragenic suppressors of mutations in the heptapeptide repeat domain of Saccharomyces cerevisiae RNA polymerase II. Genetics 123: 715-724.
42. OZENBERGERG, B. A., and G. S. ROEDER, 1991 A unique pathway of double-strand break repair operates in tandemly repeated genes. Mol. Cell. Biol. 11: 1222-1231.
43. PEARSON, W. R., and D. J. LIPMAN, 1988 Improved tools for biological sequence comparison. Proc. Natl. Acad. Sci. USA 85: 2444-2448.
44. PETES, T. D., R. E. MALONE and L. S. SYMINGTON, 1991 Recombination in yeast, pp. 407-521 in The Molecular and Celular Biology of the Yeast Saccharomyces: Genome, Vol. 1, edited by J. BROACH, E. W. JONES and J. R. PRINGLE. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
45. PRADO, F., and A. AGUILERA, 1995 Role of reciprocal exchange, one-ended invasion crossover and single-strand annealing on inverted and direct repeat recombination in yeast: different requirements for the RAD1, RAD10 and RAD52 genes. Genetics 139: 109-123.
46. PRAKASH, L., and S. PRAKASH, 1977 Isolation and characterization of MMS-sensitive mutants of Saccharomyces cerevisiae. Genetics 86: 33-55.
47. RATTRAY, A. J., and L. S. SYMINGTON, 1995 Multiple pathways for homologous recombination in Saccharomyces cerevisiae. Genetics 139: 45-56.
48. ROTHSTEIN, R. J., 1983 One step gene disruption in yeast. Methods Enzymol. 101: 202-211.
49. RUDIN, N., and J. E. HABER, 1988 Efficient repair of HO-induced chromosomal breaks in Saccharomyces cerevisiae by recombination between flanking homologous sequences. Mol. Cell. Biol. 8: 3918-3928.
50. SANGER, F., S. NICKLEN and A. R. COULSON, 1977 DNA sequencing with chain-termination inhibitors. Proc. Natl. Acad. Sci. USA 74: 5463-5467.
51. SANTOS-ROSA, H., and A. AGUILERA, 1994 Increase in incidence of chromosome instability and non-conservative recombination between repeats in Saccharomces cerevisiae hpr1Δ strains. Mol. Gen. Genet. 16: 339-346.
52. SANTOS-ROSA, H., and A. AGUILERA, 1995 Isolation and genetic analysis of extragenic supressors of the hyper-deletion phenotype of the Saccharomyces cerevisiae hpr1Δ mutation. Genetics 139: 57-66.
53. SANTOS-ROSA, H., B. CLEVER, W.-D. HEYER and A. AGUILERA, 1996 The yeast HRS1 gene encodes a polyglutamine-rich nuclear protein required for spontaneous and hpr1-induced deletions between direct repeats. Genetics 142: 705-716.
54. SCHIESTL, R. S., and R. D. GIETZ, 1989 High efficiency transformation of intact yeast cells using single stranded nucleic acids as a carrier. Curr. Genet. 16: 339-346.
55. SCHIESTL, R. H., and S. PRAKASH, 1988 RAD1, an excision repair gene of Saccharomyces cerevisiae, is also involved in recombination. Mol. Cell. Biol. 8: 3619-3626.
56. SCHIESTI., R. H., and S. PRAKASH, 1990 RAD10, an excision repair gene of Saccharomyces cerevisiae, is involved in the RAD1 pathway of mitotic recombination. Mol. Cell. Biol. 10: 2485-2491.
57. SHERMAN, F., G. R. FINK and J. B. HICKS, 1986 Methods in Yeast Genetics. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
58. SIKORSKI, R. S., and P. HIETER, 1989 A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics 122: 19-27.
59. SMITH, G. R., 1988 Homologous recombination in procaryotes. Microbiol. Rev. 52: 1-28.
60. STEWART, S. E., and G. S. ROEDER, 1989 Transcription by RNA polymerase I stimulates mitotic recombination in Saccharomyces cerevisiae. Mol. Cell. Biol. 9: 3464-3472.
61. STRUHL, K., and R. W. DAVIS, 1980 A physical, genetic and transcriptional map of the cloned his3 region of Saccharomyces cerevisiae. J. Mol. Biol. 136: 309-332.
62. THOMAS, B. J., and R. ROTHSTEIN, 1989 Elevated recombination rates in transcriptionally active DNA. Cell 56: 619-630.
63. THOMPSON, C. M., A. KOLESKE, D. M. CHAD and R. A. YOUNG, 1993 A multisubunit complex associated with the RNA polymerase II CTD and TATA-binding protein in yeast. Cell 73: 1361-1375.
64. VILETTE, D., S. D. ERHRLICH and B. MICHEL, 1995 Transcription-induced deletions in Escherichia coli plasmids. Mol. Microbiol. 17: 493-504.
65. VOEKEL-MEIMAN, K., R. L. KEIL and G. S. ROEDER, 1987 Recombination-stimulating sequences in yeast ribosomal DNA correspond to sequences regulating transcription by RNA polymerase I. Cell 48: 1071-1079.
66. WALDHERR, M., A. RAGNINI, B. JANK, R. TEPLY, G. WIESENBERGERN et al., 1993 A multitude of suppressors of group II intron-splicing defects in yeasts. Curr. Genet. 24: 301-306.
67. YUAN, L.-W., and R. L. KEIL, 1990 Distance-independence of mitotic intrachromosomal recombination in Saccharomyces cerevisiae. Genetics 124: 263-273.
68. ZHU, Y, C. L. PETERSON and M. F. CHRISTMAN, 1995 HPR1 encodes a global positive regulator of transcription in Saccharomyces cerevisiae. Mol. Cell. Biol. 15: 1698-1708.