-
1
-
-
0025694966
-
History of aspirin and its mechanism of action
-
Vane JR, Flower RJ, Botting RM: History of aspirin and its mechanism of action. Stroke 1990, 21[suppl IV]:IV-12-IV-23.
-
(1990)
Stroke
, vol.21
, Issue.4 SUPPL.
-
-
Vane, J.R.1
Flower, R.J.2
Botting, R.M.3
-
2
-
-
0027121751
-
Current concepts: The use of aspirin in ischemic heart disease
-
Willard JE, Lange RA, Hillis LD: Current concepts: the use of aspirin in ischemic heart disease. N Engl J Med 1992, 327:175-181.
-
(1992)
N Engl J Med
, vol.327
, pp. 175-181
-
-
Willard, J.E.1
Lange, R.A.2
Hillis, L.D.3
-
3
-
-
0027446426
-
Aspirin as a therapeutic agent in cardiovascular disease
-
Fuster V, Dyken ML, Vokonas PS, Hennekens C: Aspirin as a therapeutic agent in cardiovascular disease. Circulation 1993, 87:659-675.
-
(1993)
Circulation
, vol.87
, pp. 659-675
-
-
Fuster, V.1
Dyken, M.L.2
Vokonas, P.S.3
Hennekens, C.4
-
4
-
-
0027516875
-
Antiplatelet therapy: Part 1 & 2
-
Goodnight SH, Coull BM, McAnulty JH, Taylor LM: Antiplatelet therapy: part 1 & 2. West J Med 1993, 158:385-514.
-
(1993)
West J Med
, vol.158
, pp. 385-514
-
-
Goodnight, S.H.1
Coull, B.M.2
McAnulty, J.H.3
Taylor, L.M.4
-
5
-
-
0028354308
-
Drug therapy, aspirin as an antiplatelet drug
-
Patrono C: Drug therapy, aspirin as an antiplatelet drug. N Engl J Med 1994, 330:1287-1294.
-
(1994)
N Engl J Med
, vol.330
, pp. 1287-1294
-
-
Patrono, C.1
-
6
-
-
0028118792
-
Aspirin, platelets, and thrombosis: Theory and practice
-
Roth GJ, Calverley DC: Aspirin, platelets, and thrombosis: theory and practice. Blood 1994, 83:885-898.
-
(1994)
Blood
, vol.83
, pp. 885-898
-
-
Roth, G.J.1
Calverley, D.C.2
-
7
-
-
0029080229
-
Antiplatelet therapy with aspirin: From clinical trials to practice
-
Goodnight SH: Antiplatelet therapy with aspirin: from clinical trials to practice. Thromb Haemost 1995, 74:401-405.
-
(1995)
Thromb Haemost
, vol.74
, pp. 401-405
-
-
Goodnight, S.H.1
-
8
-
-
0015237292
-
Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs
-
Vane JR: Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nature 1971, 231:232-235.
-
(1971)
Nature
, vol.231
, pp. 232-235
-
-
Vane, J.R.1
-
9
-
-
0015237275
-
Aspirin selectively inhibits prostaglandin production in human platelets
-
Smith JB, Willis AL: Aspirin selectively inhibits prostaglandin production in human platelets. Nature 1971, 231:235-237.
-
(1971)
Nature
, vol.231
, pp. 235-237
-
-
Smith, J.B.1
Willis, A.L.2
-
10
-
-
0029056992
-
The structural basis of aspirin activity inferred from the crystal structure of inactivated prostaglandin H2 synthase
-
Loll PJ, Picot D, Garavito RM: The structural basis of aspirin activity inferred from the crystal structure of inactivated prostaglandin H2 synthase. Nat Struct Biol 1995, 2:637-643.
-
(1995)
Nat Struct Biol
, vol.2
, pp. 637-643
-
-
Loll, P.J.1
Picot, D.2
Garavito, R.M.3
-
11
-
-
0029047415
-
Aspirin: Now we can see it
-
Allen KN: Aspirin: now we can see it Nature Med 1995, 1:882-883.
-
(1995)
Nature Med
, vol.1
, pp. 882-883
-
-
Allen, K.N.1
-
13
-
-
0028787224
-
Cyclooxygenase-2: Regulation and relevance in inflammation
-
Mitchell JA, Larkin S, Williams TJ: Cyclooxygenase-2: regulation and relevance in inflammation. Biochem Pharmacol 1995, 50:1535-1542. A comprehensive review of the action of the two isoforms of cyclooxygenase, COX-1 and COX-2, as they relate to thrombosis, inflammation and toxicity.
-
(1995)
Biochem Pharmacol
, vol.50
, pp. 1535-1542
-
-
Mitchell, J.A.1
Larkin, S.2
Williams, T.J.3
-
14
-
-
0028167846
-
Inhibition of NF-κB by sodium salicylate and aspirin
-
Kopp E, Ghosh S: Inhibition of NF-κB by sodium salicylate and aspirin. Science 1994, 265:956-959. A provocative paper describing a potential mechanism for the anti-inflammatory action of high-dose aspirin and sodium salicylate via the inhibition of activation of NF-κB, a nuclear transcription factor.
-
(1994)
Science
, vol.265
, pp. 956-959
-
-
Kopp, E.1
Ghosh, S.2
-
15
-
-
0029556412
-
The effect of sodium salicylate and aspirin on NF-κB
-
Frantz B, O'Neill EA: The effect of sodium salicylate and aspirin on NF-κB. Science 1995, 270:2017-2018.
-
(1995)
Science
, vol.270
, pp. 2017-2018
-
-
Frantz, B.1
O'Neill, E.A.2
-
16
-
-
0029556412
-
The effect of sodium salicylate and aspirin on NF-κB: Response
-
Ghosh S, Kopp E: The effect of sodium salicylate and aspirin on NF-κB: response. Science 1995, 270:2018-2019.
-
(1995)
Science
, vol.270
, pp. 2018-2019
-
-
Ghosh, S.1
Kopp, E.2
-
17
-
-
0028951498
-
Aspirin inhibits nuclear factor-κB mobilization and monocyte adhesion in stimulated human endothelial cells
-
Weber C, Erl W, Pietsch A, Weber PC: Aspirin inhibits nuclear factor-κB mobilization and monocyte adhesion in stimulated human endothelial cells. Circulation 1995, 91:1914-1917. This study shows that salicylates (but not other NSAIDs) inhibit NF-κB mobilization, block induction of cell surface adhesion molecules, and inhibit monocyte binding to stimulated endothelial cells.
-
(1995)
Circulation
, vol.91
, pp. 1914-1917
-
-
Weber, C.1
Erl, W.2
Pietsch, A.3
Weber, P.C.4
-
18
-
-
0028858127
-
Salicylates inhibit lipopolysaccharide-induced transcriptional activation of the tissue factor gene in human monocytic cells
-
Oeth P, Mackman N: Salicylates inhibit lipopolysaccharide-induced transcriptional activation of the tissue factor gene in human monocytic cells. Blood 1995, 86:4144-4152. Another potential link between anti-inflammatory doses of salicylates and atherosclerosis or thrombosis via the suppression of tissue factor synthesis in monocytes.
-
(1995)
Blood
, vol.86
, pp. 4144-4152
-
-
Oeth, P.1
Mackman, N.2
-
19
-
-
0027193894
-
Biology of disease. Endothelial nuclear factor-κB and the initiation of the atherosclerotic lesion
-
Collins T: Biology of disease. Endothelial nuclear factor-κB and the initiation of the atherosclerotic lesion. Lab Invest 1993, 68:499-508.
-
(1993)
Lab Invest
, vol.68
, pp. 499-508
-
-
Collins, T.1
-
20
-
-
0028012437
-
Role of inflammation in coronary plaque disruption
-
Buja LM, Willerson JT: Role of inflammation in coronary plaque disruption. Circulation 1994, 89:503-505.
-
(1994)
Circulation
, vol.89
, pp. 503-505
-
-
Buja, L.M.1
Willerson, J.T.2
-
21
-
-
0025985340
-
The effect of chronic platelet inhibition with low-dose aspirin on atherosclerotic progression and acute thrombosis: Clinical evidence from the Physicians' Health Study
-
Ridker PM, Manson JE, Buring JE, Goldhaber SZ, Hennekens CH: The effect of chronic platelet inhibition with low-dose aspirin on atherosclerotic progression and acute thrombosis: clinical evidence from the Physicians' Health Study. Am Heart J 1991, 122:1588-1592.
-
(1991)
Am Heart J
, vol.122
, pp. 1588-1592
-
-
Ridker, P.M.1
Manson, J.E.2
Buring, J.E.3
Goldhaber, S.Z.4
Hennekens, C.H.5
-
22
-
-
0027238587
-
Dose-dependent effect of aspirin on carotid atherosclerosis
-
Ranke C, Hecker H, Creutzig A, Alexander K: Dose-dependent effect of aspirin on carotid atherosclerosis. Circulation 1993, 87:1873-1879.
-
(1993)
Circulation
, vol.87
, pp. 1873-1879
-
-
Ranke, C.1
Hecker, H.2
Creutzig, A.3
Alexander, K.4
-
23
-
-
0029916612
-
Aspirin in ischemic cerebrovascular disease: How strong is the case for a different dosing regimen?
-
Patrono C, Roth GJ: Aspirin in ischemic cerebrovascular disease: how strong is the case for a different dosing regimen? Stroke 1996, 27:756-760. An excellent summary of the current status of the controversy concerning the optimal dose of aspirin for the prevention of stroke and death in patients with ischemic cerebral vascular disease.
-
(1996)
Stroke
, vol.27
, pp. 756-760
-
-
Patrono, C.1
Roth, G.J.2
-
24
-
-
0027976322
-
The aspirin papers
-
Underwood MJ, More RS: The aspirin papers. BMJ 1994, 308:71-72.
-
(1994)
BMJ
, vol.308
, pp. 71-72
-
-
Underwood, M.J.1
More, R.S.2
-
25
-
-
0030021512
-
Aspirin at any dose above 30 mg offers only modest protection after cerebral ischaemia
-
Algra A, van Gijn J: Aspirin at any dose above 30 mg offers only modest protection after cerebral ischaemia. J Neurol Neurosurg Psychiatry 1996, 60:197-199.
-
(1996)
J Neurol Neurosurg Psychiatry
, vol.60
, pp. 197-199
-
-
Algra, A.1
Van Gijn, J.2
-
26
-
-
0029982983
-
Aspirin dose in stroke prevention: Beautiful hypotheses slain by ugly facts
-
Barnett HJM, Kaste M, Meldrum H, Eliasziw M: Aspirin dose in stroke prevention: beautiful hypotheses slain by ugly facts. Stroke 1996, 27:588-592.
-
(1996)
Stroke
, vol.27
, pp. 588-592
-
-
Barnett, H.J.M.1
Kaste, M.2
Meldrum, H.3
Eliasziw, M.4
-
27
-
-
0028837190
-
Drugs and surgery in the prevention of ischemic stroke
-
Barnett HM, Eliasziw M, Meldrum H: Drugs and surgery in the prevention of ischemic stroke. N Engl J Med 1995, 332:238-248.
-
(1995)
N Engl J Med
, vol.332
, pp. 238-248
-
-
Barnett, H.M.1
Eliasziw, M.2
Meldrum, H.3
-
28
-
-
0027970934
-
Development of aspirin resistance in persons with previous ischemic stroke
-
Helgason CM, Bolin KM, Hoff JA, Winkler SR, Mangat A, Tortorice KL, Brace LD: Development of aspirin resistance in persons with previous ischemic stroke. Stroke 1994, 25:2331-2336.
-
(1994)
Stroke
, vol.25
, pp. 2331-2336
-
-
Helgason, C.M.1
Bolin, K.M.2
Hoff, J.A.3
Winkler, S.R.4
Mangat, A.5
Tortorice, K.L.6
Brace, L.D.7
-
29
-
-
0027488901
-
Platelet aggregation in patients with atrial fibrillation taking aspirin or warfarin
-
Helgason CM, Hoff JA, Kondos GT, Brace LD: Platelet aggregation in patients with atrial fibrillation taking aspirin or warfarin. Stroke 1993, 24:1458-1461.
-
(1993)
Stroke
, vol.24
, pp. 1458-1461
-
-
Helgason, C.M.1
Hoff, J.A.2
Kondos, G.T.3
Brace, L.D.4
-
30
-
-
0028050259
-
Population variability in the effect of aspirin on platelet function: Implications for clinical trials and therapy
-
Pappas JM, Westengard JC, Bull BS: Population variability in the effect of aspirin on platelet function: implications for clinical trials and therapy. Arch Pathol Lab Med 1994, 118:801-804.
-
(1994)
Arch Pathol Lab Med
, vol.118
, pp. 801-804
-
-
Pappas, J.M.1
Westengard, J.C.2
Bull, B.S.3
-
31
-
-
0027944209
-
Compliance with antiplatelet therapy in patients with ischemic cerebrovascular disease: Assessment by platelet aggregation testing
-
Komiya T, Kudo M, Urabe T, Mizuno Y: Compliance with antiplatelet therapy in patients with ischemic cerebrovascular disease: assessment by platelet aggregation testing. Stroke 1994, 25:2337-2342.
-
(1994)
Stroke
, vol.25
, pp. 2337-2342
-
-
Komiya, T.1
Kudo, M.2
Urabe, T.3
Mizuno, Y.4
-
32
-
-
0029991051
-
Aspirin wars: The optimal dose of aspirin to prevent stroke
-
Hart RG, Harrison MJG: Aspirin wars: the optimal dose of aspirin to prevent stroke. Stroke 1996, 27:585-587.
-
(1996)
Stroke
, vol.27
, pp. 585-587
-
-
Hart, R.G.1
Harrison, M.J.G.2
-
33
-
-
0028876995
-
The relationship among dose, effectiveness, and side effects
-
Hirsh J, Dalen JE, Fuster V, Harker LB, Patrono C, Roth G: The relationship among dose, effectiveness, and side effects. Chest 1995, 108:247S-257S. An excellent review of the current status of aspirin as an antithrombotic agent. This is a chapter from the current American College of Chest Physicians Supplement on Antithrombotic Therapy.
-
(1995)
Chest
, vol.108
-
-
Hirsh, J.1
Dalen, J.E.2
Fuster, V.3
Harker, L.B.4
Patrono, C.5
Roth, G.6
-
34
-
-
10544233557
-
Antiplatelet therapy in cardiovascular disease
-
Edited by Hull R, Pineo GF. Philadelphia: W.B. Saunders
-
Goodnight SH: Antiplatelet therapy in cardiovascular disease. In Disorders of Thrombosis, edn 1. Edited by Hull R, Pineo GF. Philadelphia: W.B. Saunders; 1996:31-43.
-
(1996)
Disorders of Thrombosis, Edn 1
, pp. 31-43
-
-
Goodnight, S.H.1
-
35
-
-
9244251971
-
A randomized comparison of antiplatelet and anticoagulant therapy after the placement of coronary-artery stents
-
Schomig A, Neumann FJ, Kastrati A, Schuhlen H, Blasini R, Hadamitzky M, Walter H, Zitzmann-Roth EM, Richardt G, Alt E, Schmitt C, Ulm K: A randomized comparison of antiplatelet and anticoagulant therapy after the placement of coronary-artery stents. N Engl J Med 1996, 334:1084-1089. A dramatic effect of combined aspirin and ticlopidine compared with intensive anticoagulant therapy in the prevention of cardiac events and complications following coronary artery stenting.
-
(1996)
N Engl J Med
, vol.334
, pp. 1084-1089
-
-
Schomig, A.1
Neumann, F.J.2
Kastrati, A.3
Schuhlen, H.4
Blasini, R.5
Hadamitzky, M.6
Walter, H.7
Zitzmann-Roth, E.M.8
Richardt, G.9
Alt, E.10
Schmitt, C.11
Ulm, K.12
-
36
-
-
0029124114
-
Previous aspirin use may attenuate the severity of the manifestation of acute ischemic syndromes
-
Garcia-Dorado D, Théroux P, Tornos P, Sambola A, Oliveras J, Santos M, Soler JS: Previous aspirin use may attenuate the severity of the manifestation of acute ischemic syndromes. Circulation 1995, 92:1743-1748. This study suggests that patients who develop acute coronary syndromes despite chronic aspirin use have a reduced severity of thrombotic events.
-
(1995)
Circulation
, vol.92
, pp. 1743-1748
-
-
Garcia-Dorado, D.1
Théroux, P.2
Tornos, P.3
Sambola, A.4
Oliveras, J.5
Santos, M.6
Soler, J.S.7
-
37
-
-
0028846030
-
Lack of effect of aspirin in asymptomatic patients with carotid bruits and substantial carotid narrowing
-
Côté R, Battista RN, Abrahamowicz M, Langlois Y, Bourque F, Mackey A, Leclerc J, Mcllraith D, Wadup L, Berger L, et al.: Lack of effect of aspirin in asymptomatic patients with carotid bruits and substantial carotid narrowing. Ann Intern Med 1995, 123:649-655.
-
(1995)
Ann Intern Med
, vol.123
, pp. 649-655
-
-
Côté, R.1
Battista, R.N.2
Abrahamowicz, M.3
Langlois, Y.4
Bourque, F.5
Mackey, A.6
Leclerc, J.7
Mcllraith, D.8
Wadup, L.9
Berger, L.10
-
38
-
-
0028907193
-
Economics and efficacy in choosing oral anticoagulants or aspirin after myocardial infarction
-
Cairns JA, Markham BA: Economics and efficacy in choosing oral anticoagulants or aspirin after myocardial infarction. JAMA 1995, 273:965-967.
-
(1995)
JAMA
, vol.273
, pp. 965-967
-
-
Cairns, J.A.1
Markham, B.A.2
-
39
-
-
0028340390
-
Atrial fibrillation and stroke. Three new studies, three remaining questions
-
Albers GW: Atrial fibrillation and stroke. Three new studies, three remaining questions. Arch Intern Med 1994, 154:1443-1448.
-
(1994)
Arch Intern Med
, vol.154
, pp. 1443-1448
-
-
Albers, G.W.1
-
40
-
-
0028244264
-
Risk factors for stroke and efficacy of antithrombotic therapy in atrial fibrillation. Analysis of pooled data from five randomized controlled trials
-
Laupacis A, Boysen G, Connolly S, Ezekowitz M, Hart R, James K, Kistler P, Kronmal R, Petersen P, Singer D: Risk factors for stroke and efficacy of antithrombotic therapy in atrial fibrillation. Analysis of pooled data from five randomized controlled trials. Arch Intern Med 1994, 154:1449-1457.
-
(1994)
Arch Intern Med
, vol.154
, pp. 1449-1457
-
-
Laupacis, A.1
Boysen, G.2
Connolly, S.3
Ezekowitz, M.4
Hart, R.5
James, K.6
Kistler, P.7
Kronmal, R.8
Petersen, P.9
Singer, D.10
-
41
-
-
0028785453
-
Antithrombotic therapy in atrial fibrillation
-
Laupacis A, Albers G, Dalen J, Dunn M, Feinberg W, Jacobson A: Antithrombotic therapy in atrial fibrillation. Chest 1995, 108:352S-359S.
-
(1995)
Chest
, vol.108
-
-
Laupacis, A.1
Albers, G.2
Dalen, J.3
Dunn, M.4
Feinberg, W.5
Jacobson, A.6
-
42
-
-
0029059269
-
Randomised comparison of subcutaneous heparin, intravenous heparin, and aspirin in unstable angina
-
Serneri GGN, Modesti PA, Gensini GF, Branzi A, Melandri G, Poggesi L, Rostagno C, Tamburini C, Carnovali M, Magnani B: Randomised comparison of subcutaneous heparin, intravenous heparin, and aspirin in unstable angina. Lancet 1995, 345:1201-1204.
-
(1995)
Lancet
, vol.345
, pp. 1201-1204
-
-
Serneri, G.G.N.1
Modesti, P.A.2
Gensini, G.F.3
Branzi, A.4
Melandri, G.5
Poggesi, L.6
Rostagno, C.7
Tamburini, C.8
Carnovali, M.9
Magnani, B.10
-
43
-
-
0029121472
-
Efficacy and safety of combined anticoagulant and antiplatelet therapy versus anticoagulant monotherapy after mechanical heart-valve replacement: A metaanalysis
-
Cappelleri JC, Fiore LD, Brophy MT, Deykin D, Lau J: Efficacy and safety of combined anticoagulant and antiplatelet therapy versus anticoagulant monotherapy after mechanical heart-valve replacement: a metaanalysis. Am Heart J 1995, 130:547-552.
-
(1995)
Am Heart J
, vol.130
, pp. 547-552
-
-
Cappelleri, J.C.1
Fiore, L.D.2
Brophy, M.T.3
Deykin, D.4
Lau, J.5
-
44
-
-
0027291341
-
A comparison of aspirin with placebo in patients treated with warfarin after heart-valve replacement
-
Turpie AGG, Gent M, Laupacis A, Latour Y, Gunstensen J, Basile F, Klimek M, Hirsh J: A comparison of aspirin with placebo in patients treated with warfarin after heart-valve replacement N Engl J Med 1993, 329:524-529.
-
(1993)
N Engl J Med
, vol.329
, pp. 524-529
-
-
Turpie, A.G.G.1
Gent, M.2
Laupacis, A.3
Latour, Y.4
Gunstensen, J.5
Basile, F.6
Klimek, M.7
Hirsh, J.8
-
45
-
-
0026634106
-
Extracranial bleeding and other symptoms due to low dose aspirin and low intensity oral anticoagulation
-
Meade TW, Roderick PJ, Brennan PJ, Wilkes HC, Kelleher CC: Extracranial bleeding and other symptoms due to low dose aspirin and low intensity oral anticoagulation. Thromb Haemost 1992, 68:1-6.
-
(1992)
Thromb Haemost
, vol.68
, pp. 1-6
-
-
Meade, T.W.1
Roderick, P.J.2
Brennan, P.J.3
Wilkes, H.C.4
Kelleher, C.C.5
-
46
-
-
0027213615
-
Transdermal modification of platelet function: A dermal aspirin preparation selectively inhibits platelet cyclooxygenase and preserves prostacyclin biosynthesis
-
Keimowitz RM, Pulvermacher G, Mayo G, Fitzgerald DJ: Transdermal modification of platelet function: a dermal aspirin preparation selectively inhibits platelet cyclooxygenase and preserves prostacyclin biosynthesis. Circulation 1993, 88:556-561.
-
(1993)
Circulation
, vol.88
, pp. 556-561
-
-
Keimowitz, R.M.1
Pulvermacher, G.2
Mayo, G.3
Fitzgerald, D.J.4
-
47
-
-
0028800359
-
Antithrombotic effects of a nitric oxide-releasing, gastric-sparing aspirin derivative
-
Wallace JL, McKnight W, Del Soldato P, Baydoun AR, Cirino G: Antithrombotic effects of a nitric oxide-releasing, gastric-sparing aspirin derivative. J Clin Invest 1995, 96:2711-2718. A new and innovative formulation of aspirin in which a nitric oxide moiety has been linked to aspirin in an attempt to increase its antithrombotic effects and to decrease toxicity.
-
(1995)
J Clin Invest
, vol.96
, pp. 2711-2718
-
-
Wallace, J.L.1
McKnight, W.2
Del Soldato, P.3
Baydoun, A.R.4
Cirino, G.5
-
48
-
-
0030045279
-
Oral antiplatelet, antithrombotic efficacy of DMP 728, a novel platelet GPIIb/IIIa antagonist
-
Mousa SA, DeGrado WF, Mu DX, Kapil RP, Lucchesi BR, Reilly TM: Oral antiplatelet, antithrombotic efficacy of DMP 728, a novel platelet GPIIb/IIIa antagonist Circulation 1996, 93:537-543.
-
(1996)
Circulation
, vol.93
, pp. 537-543
-
-
Mousa, S.A.1
DeGrado, W.F.2
Mu, D.X.3
Kapil, R.P.4
Lucchesi, B.R.5
Reilly, T.M.6
-
49
-
-
0029059195
-
Novel antithrombotic drugs in development
-
Verstraete M, Zoldhelyi P: Novel antithrombotic drugs in development Drugs 1995, 49:856-884.
-
(1995)
Drugs
, vol.49
, pp. 856-884
-
-
Verstraete, M.1
Zoldhelyi, P.2
|