Selection of hepatitis C virus quasispecies during interferon treatment

Archives of Virology

Volumn 141, Issue 10, 1996, Pages 1921-1932

  Sakuma, I ^a   Enomoto, N ^a   Kurosaki, M ^a   Marumo, F ^a   Sato, C ^a,b  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DNA VIRUSES; HEPATITIS C VIRUS;

EID: 0029802735     PISSN: 03048608     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF01718204     Document Type: Article

References (41)

1. Davis GL, Balart LA, Schiff ER, Lindsay K, Bodenheimer HJ, Perrillo RP, Carey W, Jacobson IM, Payne J, Dienstag JL (1989) Treatment of chronic hepatitis C with recombinant interferon alfa. A multicenter randomized, controlled trial. Hepatitis International Therapy Group. N Engl J Med 321: 1 501-1 506
2. Marcellin P, Boyer N, Giostra E, Degott C, Courouce AM, Degos F, Coppere H, Cales P, Couzigou P, Benhamou JP (1991) Recombinant human alpha-interferon in patients with chronic non-A, non-B hepatitis: a multicenter randomized controlled trial from France. Hepatology 13: 393-397
3. Takada N, Takase S, Enomoto N, Takada A, Date T (1992) Clinical backgrounds of the patients having different types of hepatitis C virus genomes. J Hepatol 14: 35-40
4. Yoshioka K, Kakumu S, Wakita T, Ishikawa T, Itoh Y, Takayanagi M, Higashi Y, Shibata M, Morishita T (1992) Detection of hepatitis C virus by polymerase chain reaction to interferon-alpha therapy: relationship to genotypes of hepatitis C virus. Hepatology 16: 293-299
5. Kanai K, Kako M, Okamoto H (1992) HCV genotypes in chronic hepatitis C and response to interferon. Lancet 339: 1 543
6. Tsubota A, Chayama K, Ikeda K, Yasuji A, Koida I, Saitoh S, Hashimoto M, Iwasaki S, Kobayashi M, Hiromitsu K (1994) Factors predictive of response to interferon-alpha therapy in hepatitis C virus infection. Hepatology 19: 1 088-1 094
7. Sieck JO, Ellis ME, Alfurayh O, Ali MA, Ali HA, Ayub A, al-Fadda M, Zafar M, Halim M, Bernvil M (1993) Histologically advanced chronic hepatitis C treated with recombinant alpha-interferon: a randomized placebo-controlled double-blind cross-over study. J Hepatol 19: 418-423
8. Lau JY, Davis GL, Kniffen J, Qian KP, Urdea MS, Chan CS, Mizokami M, Neuwald PD, Wilber JC (1993) Significance of serum hepatitis C virus RNA levels in chronic hepatitis C. Lancet 341: 1 501-1 504
9. Hino K, Sainokami S, Shimoda K, lino S, Wang Y, Okamoto H, Miyakawa Y, Mayumi M (1994) Genotypes and titers of hepatitis C virus for predicting response to interferon in patients with chronic hepatitis C. J Med Virol 42: 299-305
10. Mita E, Hayashi N, Hagiwara H, Ueda K, Kanazawa Y, Kasahara A, Fusamoto H, Kamada T (1994) Predicting interferon therapy efficacy from hepatitis C virus genotype and RNA titer. Dig Dis Sci 9: 977-982
11. Holland JJ, De La Torre JC, Steinhauer DA (1992) RNA virus populations as quasispecies. Curr Top Microbiol Immunol 176: 1-20
12. Martell M, Esteban JI, Quer J, Genesca J, Weiner A, Esteban R, Guardia J, Gomez J (1992) Hepatitis C virus (HCV) circulates as a population of different but closely related genomes: quasispecies nature of HCV genome distribution. J Virol 66: 3 225-3 229
13. Kurosaki M, Enomoto N, Marumo F, Sato C (1994) Evolution and selection of hepatitis C virus variants in patients with chronic hepatitis C. Virology 205: 161-169
14. Enomoto N, Kurosaki M, Marumo F, Sato C (1994) Fluctuation of hepatitis C virus quasispecies in persistent infection and interferon treatment revealed by single strand conformation polymorphism analysis. J Gen Virol 75: 1 361-1 369
15. Kurosaki M, Enomoto N, Tanaka Y, Hoshino Y, Izumi N, Marumo F, Sato C (1995) Detection and analysis of replicating hepatitis C virus quasispecies in hepatocellular carcinoma tissue. J Hepatol 22: 527-535
16. Kato N, Sekiya H, Ootsuyma Y, Nakazawa T, Hijikata M, Ohkoshi S, Shimotono K (1993) Humoral immune response to hypervariable region 1 of the putative envelope glycoprotein (gp70) of hepatitis C virus. J Virol 67: 3 923-3 030
17. Weiner AJ, Brauer MJ, Rosenblatt J, Richman KH, Tung J, Crawford K, Bonino F, Saracco G, Choo QL, Houghton M (1991) Variable and hypervariable domains are found in the regions of HCV corresponding to the flavivirus envelope and NS1 proteins and the pestivirus envelope glycoproteins. Virology 180: 842-848
18. Kumar U, Monjardino J, Thomas HC (1994) Hypervariable region of hepatitis C virus envelope glycoprotein (E2/NS1) in an agammaglobulinemic patient. Gastroenterology 106: 1 072-1 075
19. Enomoto N, Sato C, Kurosaki M, Marumo F (1994) Hepatitis C virus after interferon treatment has the variation in the hypervariable region of envelope 2 gene. J Hepatol 20: 252-261
20. Higashi Y, Kakumu S, Yoshioka K, Wakita T, Mizokami M, Ohba K, Ito Y, Ishikawa T, Takayanagi M, Nagai Y (1993) Dynamics of genome change in the E2/NS1 region of hepatitis C virus in vivo. Virology 197: 659-668
21. Okada S, Akahane Y, Suzuki H, Okamoto H, Mishiro S (1992) The degree of variability in the amino terminal region of the E2/NS1 protein of hepatitis C virus correlates with responsiveness to interferon therapy in viremic patients. Hepatology 16: 619-624
22. Orita M, Suzuki Y, Sekiya T, Hayashi K (1989) Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction. Genomics 5: 874-879
23. Yap EP-H, Lo Y-MD, Cooper K, Fleming KA, McGee JO (1992) Exclusion of false-positive PCR viral diagnosis by single-strand conformation polymorphism. Lancet 340: 736
24. Okamoto H, Okada S, Sugiyama Y, Tanaka T, Sugai Y, Akahane Y, Machida A, Mishiro S, Yoshizawa H, Miyakawa Y (1990) Detection of hepatitis C virus RNA by a two-stage polymerase chain reaction with two pairs of primers deduced from the 5′-noncoding region. Jpn J Exp Med 60: 215-222
25. Simmonds P, Alberti A, Alter HJ, Bonino F, Bradley DW, Brechot C, Brouwer JT, Chan SW, Chayama K, Chen DS, Choo QL, Colombo M, Cuypers T, Date T, Dusheiko GM, Esteban JI, Fay O, Hadziyanni's SJ, Han J, Hatzakis A, Holmes EC, Hotta H, Houghton M, Irvine B (1994) A proposed system for the nomenclature of hepatitis C viral genotypes. Hepatology 19: 1 321-1 324
26. Okamoto H, Sugiyama Y, Okada S, Kurai K, Akahane Y, Sugai Y, Tanaka T, Sato K, Tsuda F, Miyakawa Y, Mayumi M (1992) Typing hepatitis C virus by polymerase chain reaction with type-specific primers: application to clinical surveys and tracing infectious sources. J Gen Virol 73: 673-679
27. Desmet VJ, Gerber M, Hoofnagle JH, Manns M, Scheuer PJ (1994) Classification of chronic hepatitis: diagnosis, grading and staging. Hepatology 19: 1 513-1 520
28. Chomczynski P, Sacchi N (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162: 156-159
29. Saiki RK, Gelfand DH, Stoffel S, Scharf SJ, Higuchi R, Horn GT, Mullis KB, Erlich HA (1988) Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerese. Science 239: 487-491
30. Gyllensten UB, Erlich HA (1988) Generation of single-stranded DNA by the plymerase chain reaction and its application to direct sequencing of the HLA-DQA locus. Proc Natl Acad Sci USA 85: 7 652-7 656
31. Yap E-PH, McGee JO (1992) Nonisotopic SSCP detection in PCR products by ethidium bromide staining. Trends Genet 8: 49
32. Kato N, Hijikata M, Ootsuyama Y, Nakagawa M, Ohkoshi S, Sugimura T, Shimotohno K (1990) Molecular cloning of the human hepatitis C virus genome from Japanese patients with non-A, non-B hepatitis. Proc Natl Acad Sci USA 87: 9 254-9 528
33. Enomoto N, Sakuma I, Asahina Y, Kurosaki M, Murakami T, Yamamoto C, Izumi N, Marumo F, Sato C (1995) Comparison of full-length sequences of interferon sensitive and resistant hepatitis C virus 1b: sensitivity to interferon is conferred by amino acid substitutions in the NS5A region. J Clin Invest 96: 224-230
34. Enomoto N, Sakuma I, Asahina Y, Kurosaki M, Murakami T, Yamamoto C, Ogura Y, Izumi N, Marumo F, Sato C (1996) Mutations in the nonstructural protein 5A gene and response to interferon in patients with chronic hepatitis C virus 1b infection. N Engl J Med 334: 77-81
35. Sekiya H, Kato N, Ootsuyama Y, Nakazawa T, Yamauchi K, Shimotohno K (1994) Genetic alterations of the putative envelope proteins encoding region of the hepatitis C virus in the progression to relapsed phase from acute hepatitis: humoral immune response to hypervariable region 1. Int J Cancer 57: 664-670
36. Weiner AJ, Geysen HM, Christopherson C, Hall JE, Mason TJ, Saracco G, Bonino F, Crawford K, Marion CD, Crawford KA, Brunetto M, Barr PJ, Miyamura T, McHutchinson J, Houghton M (1992) Evidence for immune selection of hepatitis C virus (HCV) putative envelope glycoprotein variants: potential role in chronic HCV infections. Proc Natl Acad Sci USA 89: 3 468-3 472
37. Kumar U, Brown J, Monjardino J, Thomas HC (1993) Sequence variation in the large envelope glycoprotein (E2/NS1) of hepatitis C virus during chronic infection. J Infect Dis 167: 726-730
38. Kurosaki M, Enomoto N, Marumo F, Sato C (1993) Rapid sequence variation of the hypervariable region of hepatitis C virus during the course of chronic infection. Hepatology 18: 1 293-1 299
39. Nakazawa T, Kato N, Ootsuyama Y, Sekiya H, Fujioka T, Shibuya A, Shimotohno K (1994) Genetic alteration in the hepatitis C virus hypervariable region obtained from an asymptomatic carrier. Int J Cancer 56: 204-207
40. Okamoto H, Kojima M, Okada S, Yoshizawa H, lizuka H, Tanaka T, Muchmore EE, Peterson DA, Ito Y, Mishiro S (1992) Genetic drift of hepatitis C virus during an 8.2-year infection in a chimpanzee: variability and stability. Virology 190: 894-899
41. Ogata N, Alter HJ, Miller RH, Purcell RH (1991) Nucleotide sequence and mutation rate of the H strain of hepatitis C virus. Proc Natl Acad Sci USA 88: 3 392-3 396