Gene marking

Human Gene Therapy

Volumn 7, Issue 16, 1996, Pages 1927-1936

  Brenner, Malcolm ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOGENIC BONE MARROW TRANSPLANTATION; CELL POPULATION; GENE TRANSFER; HEMATOPOIETIC STEM CELL; HUMAN; MARKER GENE; REVIEW; STEM CELL TRANSPLANTATION;

EID: 0029800108     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/hum.1996.7.16-1927     Document Type: Review

References (54)

1. APPELBAUM, F.R., and BUCKNER, C.D. (1986). Overview of the clinical relevance of autologous bone marrow transplantation. Clin. Haematol. 15, 1-18.
2. BIENZLE, D., ABRAMS-OGG, A.C.G., KRUTH, S.A., ACKLAND-SNOW, J., CARTER, R., DICK, J., JACOBS, R., KAMEL-REID, S., and DUBE, I. (1994). Gene transfer into hematopoietic stem cells: Long-term maintenance of in vitro activated progenitors without marrow ablation. Proc. Natl. Acad. Sci. USA 91, 350-354.
3. BJORKSTRAND, B., GAHRTON, G., SIRAC DILBER, M., LJUNGMAN, P., SMITH, C.I.E., and XANTHOPOULOS, K.G. (1994). Retroviral-mediated gene transfer of CD34-enriched bone marrow and peripheral blood cells during autologous stem cell transplantation for multiple myeloma. Hum. Gene Ther. 5, 1279-1286.
4. + bone marrow cells. Blood 82, 1975-1980.
5. BODINE, D.M., SEIDEL, N.B., and ORLIC, D. (1996). Bone marrow collected 14 days after in vivo administration of granulocyte colony-stimulating factor and stem cell factor to mice has 10-fold more repopulating ability than untreated bone marrow. Blood 88, 89-97.
6. BOURGAULT, I., GOMEZ, A., GOMARD, E., and LEVY, J.P. (1991). Limiting-dilution analysis of the HLA restriction of anti-Epstein-Barr virus-specific cytolytic T lymphocytes. Clin. Exp. Immunol. 84, 501-507.
7. BRENNER, M.K., REITTIE, J.E., GROB, J., WIMPERIS, J.Z., STEPHENS, S., PATTERSON, J., HOFFBRAND, A.V., and PRENTICE, H.G. (1986). The contribution of large granular lymphocytes to B cell activation and differentiation after T cell depleted allogeneic bone marrow transplantation. Transplantation 42, 257-261.
8. BRENNER, M., MIRRO, J., JR., HURWITZ, C., SANTANA, V., IHLE, J., KRANCE, R., RIBEIRO, R., ROBERTS, W.M., MAHMOUD, H., SCHELL, M., and GARTH, K. (1991). Autologous bone marrow transplant for children with AML in first complete remission: use of marker genes to investigate the biology of marrow reconstitution and the mechanism of relapse. Hum. Gene Ther. 2, 137-159.
9. BRENNER, M.K., RILL, D.R., HOLLADAY, M.S., HESLOP, H.E., MOEN, R.C., BUSCHLE, M., KRANCE, R.A., SANTANA, V.M., ANDERSON, W.F., and IHLE, J.N. (1993a). Gene marking to determine whether autologous marrow infusion restores long-term haemopoiesis in cancer patients. Lancet 342, 1134-1137.
10. BRENNER, M.K., RILL, D.R., MOEN, R.C., KRANCE, R.A., MIRRO, J., JR., ANDERSON, W.F., and IHLE, J.N. (1993b). Gene-marking to trace origin of relapse after autologous bone marrow transplantation. Lancet 341, 85-86.
11. BRENNER, M., SANTANA, V., BOWMAN, L., FURMAN, W., HESLOP, H., KRANCE, R., MAHMOUD, H., BOYETT, J., MOSS, T., MOEN, R.C., and MILLS, B. (1993). Use of marker genes to investigate the mechanism of relapse and the effect of bone marrow purging in autologous transplantation for stage D neuroblastoma: Hum. Gene Ther. 4, 809-820.
12. BRENNER, M.K., HESLOP, H.E., RILL, D. LI, C., NILSON, T., ROBERTS, M., SMITH, C., and KRANCE, R. (1994a). Gene transfer and bone marrow transplantation. Cold Spring Harbor Symp. Quant. Biol. LIX, 691-697.
13. BRENNER, M.K., KRANCE, R., HESLOP, H.E., SANTANA, V., IHLE, J., RIBEIRO, R., ROBERTS, W.M., MAHMOUD, H., BOYETT, J.M., MOEN, R.C., and KLINGEMANN, H.G. (1994b). Assessment of the efficacy of purging by using gene marked autologous marrow transplantation for children with AML in first complete remission. Hum. Gene Ther. 5, 481-499.
14. BRUGGER, W., HEIMFELD, S., BERENSON, R.J., MERTELSMANN, R., and KANZ, L. (1995). Reconstitution of hematopoiesis after high dose chemotherapy by autologous progenitor cells generated ex vivo. N. Engl. J. Med. 333, 283-287.
15. CORNETTA, K., TRICOT, G., BROUN, E.R., HROMAS, R., SROUR, E., HOFFMAN, R., ANDERSON, W.F., MOEN, R.C., and MORGAN, R.A. (1992). Retroviral-mediated gene transfer of bone marrow cells during autologous bone marrow transplantation for acute leukemia. Hum. Gene Ther. 3, 305-318.
16. CORNETTA, K., SROUR, E.F., MOORE, A., DAVIDSON, A., BROUN, R., HROMAS, R., MOEN, R., MORGAN, R., RUBIN, L., ANDERSON, W.F., HOFFMAN, R., and TRICOT, G. (1996). Retroviral gene transfer in autologous bone marrow transplantation for adult acute leukemia. Hum. Gene Ther. 7, 1323-1329.
17. DEISSEROTH, A.B., KANTARJIAN, H., TALPAZ, M., CHAMPLIN, R., READING, C., ANDERSSON, B., and CLAXTON, D. (1991). Autologous bone marrow transplantation for CML in which retroviral markers are used to discriminate between relapse which arises from systemic disease remaining after preparative therapy versus relapse due to residual leukemia cells in autologous marrow: A pilot trial. Hum. Gene Ther. 2, 359-376.
18. DEISSEROTH, A.B., KANTARJIAN, H., TALPAZ, M., CHAMPLIN, R., READING, C., ANDERSSON, B., and CLAXTON, D. (1993). Use of two retroviral vectors to test relative contribution of marrow and peripheral blood autologous cells to recovery after preparative therapy. Hum. Gene Ther. 4, 71-85.
19. DEISSEROTH, A.B., ZU, Z., CLAXTON, D., HANANIA, E.G., FU, S., ELLERSON, D., GOLDBERG, L., THOMAS, M., JANICEK, J., ANDERSON, W.F., HESTER, J., KORBLING, M., DURETT, A., MOEN, R., and BERENSON, R. (1994). Genetic marking shows that Ph+ cells present in autologous transplants of chronic myelogenous leukemia (CML) contribute to relapse after autologous bone marrow in CML. Blood 83, 3068-3076.
20. DONAHUE, R.E., KESSLER, S.W., BODINE, D., MCDONAGH, K., DUNBAR, C., GOODMAN, S., AGRICOLA, B., MYRNE, E., RAFFELD, M., MOEN, R., BACHER, J., ZSEBO, K.M., and NIENHUIS, A.W. (1992). Helper virus induced T cell lymphoma in non-human primates after retroviral mediated gene transfer. J. Exp. Med. 176, 1125-1135.
21. DUNBAR, C.E., NIENHUIS, A.W., STEWART, F.M., QUESENBERRY, P., O'SHAUGHNESSY, J., COWAN, K., COTTLER-FOX, M., LEITMAN, S., GOODMAN, S., SORRENTINO, B.P., MCDONAGH, K., YOUNG, N.S., DONAHUE, R., BODINE, D., and CASSEL, A. (1993). Genetic marking with retroviral vectors to study the feasibility of stem cell gene transfer and the biology of hemopoietic reconstitution after autologous transplantation in multiple myeloma, chronic myelogenous leukemia, or metastatic breast cancer. Hum. Gene Ther. 4, 205-222.
22. DUNBAR, C.E., BODINE, D.M., SORRENTINO, B., DONAHUE, R., COTTLER-FOX, M., O'SHAUGHNESSY, J., COWAN, K., CARTER, C., DOREN, S., CASSEL, A., and NIENHUIS, A.W. (1994). Gene transfer into hematopoietic cells: Implications for cancer therapy. Ann. NY Acad. Sci. 716, 216-224.
23. DUNBAR, C.E., COTTLER-FOX, M., O'SHAUNESSY, J.A., DOREN, S., CARTER, C., BERENSON, R., BROWN, S., MOEN, R.C., GREENBLATT, J., STEWART, F.M., LEITMAN, S.F., WILSON, W.H., COWAN, K., YOUNG, N.S., and NIENHUIS, A.W. (1995). Retrovirally marked CD34-enriched peripheral blood and marrow cells contribute to long term engraftment after autologous transplantation. Blood 85, 3048-3057.
24. HANENBERG, H., XIAO, X.L., DILLOO, D., HASHINO, K., KATO, I., and WILLIAMS, D.A. (1996). Co-localization of retrovirus and target cells on specific fibronection adhesion domains for increased genetic transduction of mammalian cells. Nature Med. 2, 876.
25. HESLOP, H.E., BRENNER, M.K., and ROONEY, C.M. (1994a). Donor T cells to treat EBV-associated lymphoma. N. Engl. J. Med. 331, 679-680.
26. HESLOP, H.E., BRENNER, M.K., ROONEY, C.M., KRANCE, R.A., ROBERTS, W.M., ROCHESTER, R., SMITH, C.A., TURNER, V., SIXBEY, J., MOEN, R., and BOYETT, J.M. (1994b). Admini-stration of neomycin-resistance-gene-marked EBV-specific cytotoxic T lymphocytes to recipients of mismatched-related or phenotypically similar unrelated donor marrow grafts. Hum. Gene Ther. 5, 381-397.
27. HESLOP, H.E., NG, C.Y.C., LI, C., SMITH, C.A., LOFTIN, S.K., KRANCE, R.A., BRENNER, M.K., and RODNEY, C.M. (1996). Long-term restoration of immunity against Epstein-Barr virus infection by adoptive transfer of gene-modified virus-specific T lymphocytes. Nature Med. 2, 551-555.
28. JONES, R.J. (1993). Autologous bone marrow transplantation. Curr. Opin. Oncol. 5, 270-275.
29. JUNG, S., and SCHLUESNER, H.J. (1991). Human T lymphocytes recognize a peptide of single point-mutated, oncogenic ras proteins. J. Exp. Med. 173, 273-276.
30. KOHN, D.B., WEINBERG, K.I., NOLTA, J.A., HEISS, L.N., LENARSKY, C., CROOKS, G.M., HANLEY, M.E., ANNETT, G., BROOKS, J.S., EL-KHOUREIY, A., LAWRENCE, K., WELLS, S., MOEN, R.C., BASTIAN, J., WILLIAMS-HERMAN, D.E., ELDER, M., WARA, D., BOWEN, T., HERSHFIELD, M.S., MULLEN, C.A., BLAESE, M., and PARKMAN, R. (1995). Engraftment of gene-modified umbilical cord blood in neonates with adenosine deaminase deficiency. Nature Med. 2, 876.
31. LEDLEY, F.D., WOO, S.L.C., FERRY, G.D., WHISENNAND, H.H., BRANDT, M.L., DARLINGTON, G.J., DEMMLER, G.J., FINEGOLD, M.J., POKORNY, W.J., ROSENBLATT, H., SCHWARTZ, P., ANDERSON, W.F., and MOEN, R.C. (1991). Hepatocellular transplantation in acute hepatic failure and targeting genetic markers to hepatic cells. Hum. Gene Ther. 2, 331-358.
32. MAVILIO, F., FERRARI, G., ROSSINI, S., NOBILI, N., BONINI, C., CASORATI, G., TRAVERSARI, C., and BORDIGNON, C. (1994). Peripheral blood lymphocytes as target cells of retroviral vector-mediated gene transfer. Blood 83, 1988-1997.
33. PAPADOPOULOS, E.B., LADANYI, M., EMANUEL, D., MACKINNON, S., BOULAD, F., CARABASI, M.H., CASTRO-MALASPINA, H., CHILDS, B.H., GILLIO, A.P., SMALL, T.N., YOUNG, J.W., KERNAN, N.A., and O'REILLY, R.J. (1994). Infusions of donor leukocytes to treat Epstein-Barr virus-associated lymphoproliferative disorders after allogeneic bone marrow transplantation. N Engl. J. Med. 330, 1185-1191.
34. PAWLIUK, R., KAY, R., LANSDORP, P., and HUMPHRIES, R.K. (1994). Selection of retrovirally transduced hematopoietic progenitor cells using CD24 as a marker of gene transfer. Blood 84, 2868-2877.
35. RICKINSON, A.B., MOSS, D.J., WALLACE, L.E., ROWE, M., MISKO, I.S., EPSTEIN, M.A., and POPE, J.H. (1981). Long-term cell-mediated immunity to Epstein-Barr virus. Cancer Res 41, 4216.
36. RIDDELL, S.R., WATANABE, K.S., GOODRICH, J.M., LI, C.R., AGHA, M.E., and GREENBERG, P.D. (1992). Restoration of viral immunity in immunodeficient humans by the adoptive transfer of T cell clones. Science 257, 238-241.
37. RIDDELL, S.R., ELLIOT, M., LEWINSOHN, D.A., GILBERT, M.J., WILSON, L., MANLEY, S.A., LUPTON, S.D., OVERELL, R.W., REYNOLDS, T.C., COREY, L., and GREENBERG, P.D. (1996). T-cell mediated rejection of gene-modified HIV-specific cytotoxic T lymphocytes in HIV-infected patients. Nature Med. 2, 216-223.
38. RILL, D.R., SANTANA, V.M., ROBERTS, W.M., NILSON, T., BOWMAN, L.C., KRANCE, R.A., HESLOP, H.E., MOEN, R.C., IHLE, J.N., and BRENNER, M.K. (1994). Direct demonstration that autologous bone marrow transplantation for solid tumors can return a multiplicity of tumorigenic cells. Blood 84, 380-383.
39. RIVERA, G.K., PINKEL, D., SIMONE, J.V., HANCOCK, M.L., and CRIST, W.M. (1993). Treatment of acute lymphoblastic leuklemia - 30 year's experience at St. Jude Children's Research Hospital. N. Engl. J. Med. 329, 1289-1295.
40. ROONEY, C.M., SMITH, C.A., NG, C., LOFTIN, S.K., LI, C., KRANCE, R.A., BRENNER, M.K., and HESLOP, H.E. (1995). Use of gene-modified virus-specific T lymphocytes to control Epstein-Barr virus-related lymphoproliferation. Lancet 345, 9-13.
41. ROSENBERG, S.A., AEBERSOLD, P., CORNETTA, K., KASID, A., MORGAN, R.A., MOEN, R., KARSON, E.M., LOTZE, M.T., YANG, J.C., TOPALIAN, S.L., MERINO, M.J., CULVER, J., MILLER, D., BLAESE, R.M., and ANDERSON, W.F. (1990a). Gene transfer into humans - immunotherapy of patients with advanced melanoma, using tumor-infiltrating lymphocytes modified by retroviral gene transduction. N. Engl. J. Med. 323, 570-578.
42. ROSENBERG, S.A., BLAESE, R.M., and ANDERSON, W.F. (1990b). The N2-TIL human gene transfer clinical protocol. Hum. Gene Ther. 1, 73-92.
43. SANTANA, V.M., BRENNER, M.K., IHLE, J., KRANCE, R., FURMAN, W., BOWMAN, L., RIBEIRO, R., HURWITZ, C., MAHMOUD, H., MOEN, R.C., and ANDERSON, W.F. (1991a). A phase I trial of high-dose carboplatin and etoposide with autologous marrow support for treatment of stage D neuroblastoma in first remission: use of marker genes to investigate the biology of marrow reconstitution and the mechanism of relapse. Hum. Gene Ther. 3, 257-272.
44. SANTANA, V.M., BRENNER, M.K., IHLE, J., KRANCE, R., FURMAN, W., BOWMAN, L., RIBEIRO, R., HURWITZ, C., MAHMOUD, H., MOEN, R.C., and ANDERSON, W.F. (1991b). A phase I trial of high-dose carboplatin and etoposide with autologous marrow support for treatment of relapse/refractory neuroblastoma without apparent bone marrow involvement: use of marker genes to investigate the biology of marrow reconstitution and the mechanism of relapse. Hum. Gene Ther. 2, 273-286.
45. SANTOS, G.W., YEAGER, A.M., and JONES, R.J. (1989). Autologous bone marrow transplantation. Annu. Rev. Med. 40, 99-112.
46. SCHUENING, F., MILLER, A.D., TOROK-STORB, B., BENSINGER, W., STORB, R., REYNOLDS, T., FISHER, L., BUCKNER, C.D., and APPELBAUM, F.R. (1994). Study on contribution of genetically marked peripheral blood repopulating cells to hematopoietic reconstitution after transplantation. Hum. Gene Ther. 5, 1523-1534.
47. SELVAGGI, K.J., WILSON, J.W., MILLS, L.E., CORNWELL, G.G., III, HURD, D., DODGE, W., GINGRICH, R., MARTIN, S.E., MCMILLAN, R., MILLER, W., and BALL, E.D. (1994). Improved outcome for high-risk acute myeloid leukemia patients using autologous bone marrow transplantation and monoclonal antibody-purged bone marrow. Blood 83, 1698-1705.
48. SMITH, C.A., NG, C.Y.C., HESLOP, H.E., HOLLADAY, M.S., RICHARDSON, S., TURNER, E.V., LOFTIN, S.K., LI, C., BRENNER, M.K., and ROONEY, C.M. (1995) Production of genetically modified EBV-specific cytotoxic T cells for adoptive transfer to patients at high risk of EBV-associated lymphoproliferative disease. J. Hematother. 4, 73-479.
49. SPITZER, G., VELASQUEZ, W., DUNPHY, F.R., and SPENCER, V. (1992). Autologous bone marrow transplantation in solid tumors. Curr. Opin. Oncol. 4, 272-278.
50. STEWART, A.K., DUBE, I.D., KAMEL-REID, S., and KEATING, A. (1995). A Phase I study of autologous bone marrow transplantation with stem cell gene marking in multiple myeloma. Hum. Gene Ther. 6, 107-110.
51. STRAUS, S.E., COHEN, J.I., TOSATO, G., and MEIER, J. (1992). Epstein-Barr virus infections: Biology, pathogenesis and management. Ann. Intern. Med. 118, 45-58.
52. THE UNIVERSITY OF TEXAS M.D. ANDERSON CANCER CENTER. (1991). Autologous bone marrow transplantation for CML in which retroviral markers are used to discriminate between relapse which arises from systemic disease remaining after preparative therapy versus relapse due to residual leukemia cells in autologous marrow: A pilot trial. Hum. Gene Ther. 2, 359-376.
53. VON MELCHNER, H., and HOUSMAN, D.E. (1987). The expression of neomycin phosphotransferase in human promyelocytic leukemia cells (HL60) delays their differentiation. Oncogene 2, 137-140.
54. WALTER, E.A., GREENBERG, P.D., GILBERT, M.J., FINCH, R.J., WATANABE, K.S., THOMAS, E.D., and RIDDELL, S.R. (1995). Reconstitution of cellular immunity against cytomegalovirus in recipients of allogeneic bone marrow by transfer of T-cell clones from the donor. N. Engl. J. Med. 333, 1038-1044.