Is maternal obesity a risk factor for anencephaly and spina bifida?

Epidemiology

Volumn 7, Issue 5, 1996, Pages 507-512

  Watkins, Margaret L ^a,b   Scanlon, Kelley S ^a,c   Mulinare, Joseph ^a   Khoury, Muin J ^a  

^a NATIONAL CENTER FOR ENVIRONMENTAL HEALTH   (United States)

^b CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^c NATIONAL CENTER FOR CHRONIC DISEASE PREVENTION AND HEALTH PROMOTION   (United States)

Author keywords

abnormalities; anencephaly; fatness; obesity; pregnancy outcome; spina bifida

Indexed keywords

ANENCEPHALUS; ARTICLE; BODY MASS; CONTROLLED STUDY; FEMALE; HIGH RISK PREGNANCY; HUMAN; MAJOR CLINICAL STUDY; MORBID OBESITY; NEURAL TUBE DEFECT; NUTRITIONAL STATUS; PREGNANCY COMPLICATION; PRIORITY JOURNAL; SPINA BIFIDA;

EID: 0029799199     PISSN: 10443983     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001648-199609000-00010     Document Type: Article

References (32)

1. Cragan JD, Roberts HE, Edmonds LD, Khoury MJ, Kirby RS, Shaw GM, Velie EM, Merz RD, Forrester MB, Williamson RA, Krishnamurti DS, Stevenson RE, Dean JH. Surveillance for anencephaly and spina bifida and the impact of prenatal diagnosis - United States, 1985-1994. In: CDC Surveillance Summaries, August 25, 1995 (No. SS-4). MMWR 1995;44:1-13.
2. Centers for Disease Control. Recommendations for the use of folic acid to reduce the number of cases of spina bifida and other neural tube defects (No. RR-14). MMWR 1992;41:1-7.
3. Xavier Pi-Sunyer F. Obesity. In: Shils ME, Olson JA, Shike M, eds. Modern Nutrition in Health and Disease. 8th ed. Philadelphia: Lea & Febiger, 1993;984-1001.
4. Kuczmarski RJ, Flegal KM, Campbell SM, Johnson CL. Increasing prevalence of overweight among US adults. JAMA 1994;272:205-211.
5. National Center for Health Statistics. Public Use Data Tape Documentation - 1988 National Maternal and Infant Health Survey. Hyattsville, MD: Department of Health and Human Services, 1991.
6. Czeizel AE, Dudas I. Prevention of the first occurrence of neural-tube defects by periconceptional vitamin supplementation. N Engl J Med 1992;327: 1832-1835.
7. MRC Vitamin Study Research Group. Prevention of neural tube defects: results of the Medical Research Council Vitamin Study. Lancet 1991;338: 131-137.
8. Mulinare J, Cordero JF, Erickson JD, Berry RJ. Periconceptional use of multivitamins and the occurrence of neural tube defects. JAMA 1988;260: 3141-3145.
9. Werler MM, Cheaper S, Mitchell AA. Periconceptional folic acid exposure and risk of occurrent neural tube defects. JAMA 1993;269:1257-1261.
10. Hötzel D. Suboptimal nutritional status in obesity (selected nutrients). Bibl Nutr Dieta 1986;21:36-41.
11. Beccera JE, Khoury MJ, Cordero JF, Erickson JD. Diabetes mellitus during pregnancy and the risks for specific birth defects: a population-based case-control study. Pediatrics 1990;85:1-9.
12. Richards IDG. Congenital malformations and environmental influences in pregnancy. Br J Prev Soc Med 1969;23:218-225.
13. Naeye RL. Maternal body weight and pregnancy outcome. Am J Clin Nutr 1990;52:273-279.
14. Wald NJ, Cuckle HS. Recent advances in screening for neural tube defects and Down's syndrome. Baillieres Clin Obstet Gynaecol 1987;1:649-676.
15. Johnson AM, Palomaki GE, Haddow JE. The effect of adjusting maternal serum alpha-fetoprotein levels for maternal weight in pregnancies with fetal open spina bifida. Am J Obstet Gynecol 1990;163:9-11.
16. Haddow JE, Smith DE, Sever J. The effect of maternal weight on maternal serum alpha-fetoprotein. Br J Obstet Gynaecol 1982;89:93.
17. Waller DK, Mills JL, Simpson JL, Cunningham GC, Conley MR, Lassman MR, Rhoads GC. Are obese women at higher risk for producing malformed offspring? Am J Obstet Gynecol 1994;170:541-548.
18. Lynberg MC, Edmonds LG. Surveillance of birth defects. In: Halperin W, Baker EL, eds. Public Health Surveillance. New York: Van Nostrand Reinhold, 1992;157-177.
19. Erickson JD, Mulinare J, McClain PW, Fitch TG, James LM, McClearn AB, Adams MJ. Vietnam veterans' risk for fathering babies with birth defects. JAMA 1984;252:903-912.
20. Erickson JD, Mulinare J, McClain PW, Fitch TG, James LM, McClearn AB, Adams MJ. Vietnam Veterans' Risk for Fathering Babies with Birth Defects. Atlanta: Centers for Disease Control and Prevention, 1984.
21. Subcommittee on Nutritional Status and Weight Gain during Pregnancy, Institute of Medicine. Nutrition during Pregnancy. Washington DC: National Academy Press, 1990.
22. SAS Institute. SAS/STAT User's Guide. Version 6. Cary, NC: SAS Institute, 1989.
23. Greenland S. Dose-response and trend analysis in epidemiology: alternatives to categorical analysis. Epidemiology 1995;6:356-365.
24. Cogswell ME, Serdula MK, Mokdad AH, Williamson DF. Intentional weight loss during pregnancy (Abstract). American Public Health Association Epidemiology Exchange, Late-Breaker Session: 1993, San Francisco, CA. Washington DC: American Public Health Association, 1993.
25. Reece EA, Homko CJ, Wu YK, Wiznitzer A. Metabolic fuel mixtures and diabetic embryopathy. Clin Perinatol 1993;20:517-532.
26. Considine RV, Sinha MK, Heiman ML, Kriauciunas A, Stephens TW, Nyce MR, Ohannesian JP, Marco CC, McKee LJ, Bauer TL, Caro JF. Serum immunoreactive-leptin concentrations in normal-weight and obese humans. N Engl J Med 1996;334:292-295.
27. Senti FR, Pilch SM. Assessment of the folate nutritional status of the U.S. population based on data collected in the second National Health and Nutrition Examination Survey, 1976-1980. Bethesda, MD: Life Sciences Research Office, Federation of American Societies for Experimental Biology, 1984.
28. Kaufman FL, Gold EB, Schenker MB, Hammond SK. The effects of exposure to smoke on folate status (Abstract). In: Proceedings of the Twenty-sixth Annual Meeting of the Society for Epidemiologic Research, June 16-28, 1993, Keystone, CO, 1993;166.
29. Assessment of the status of folate and vitamin B-12. In: Gibson RS. Principles of Nutritional Assessment. New York: Oxford University Press, 1990; 465.
30. Stewart AL. The reliability and validity of self-reported weight and height. J Chron Dis 1982;35:295-309.
31. Perry GS, Byers TE, Mokdad AH, Serdula MK, Williamson DF. The validity of self-reports of past body weights by U.S. adults. Epidemiology 1995;6:61-66.
32. Miettinen OS. Proportion of disease caused or prevented by a given exposure, trait or intervention. Am J Epidemiol 1974;99:325-332.