The extragenomic action of progesterone on human spermatozoa: Evidence for a ubiquitous response that is rapidly down-regulated

Endocrinology

Volumn 137, Issue 9, 1996, Pages 3999-4009

  Aitken, R John ^a   Buckingham, Donna W ^a   Irvine, D Stewart ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; BOVINE SERUM ALBUMIN; FLUORESCENT DYE; GUANINE NUCLEOTIDE BINDING PROTEIN; MUSCIMOL; PHOSPHOLIPASE C; PROGESTERONE; PROGESTERONE RECEPTOR;

ACROSOME REACTION; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CONTROLLED STUDY; DOWN REGULATION; FERTILIZATION; GENOME; HORMONE ACTION; HUMAN; HUMAN CELL; MALE; MALE FERTILITY; PRIORITY JOURNAL; SECOND MESSENGER; SEMEN ANALYSIS; SIGNAL TRANSDUCTION; SPERMATOZOON;

EID: 0029793695     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.137.9.8756577     Document Type: Article

References (43)

1. Blackmore PF, Fisher JF, Spilman CH, Im WB, Bleasdale JE 1995 Effect of steroids on calcium fluxes in human sperm. In: Fenichel P, Parinaud J (eds) Human Sperm Acrosome Reaction. J Libbey, London, pp 165-179
2. Osman RA, Andria ML, Jones AD, Meizel S 1989 Steroid induced exocytosis: the human sperm acrosome reaction. Biochem Biophys Res Commun 160:828-834
3. Sueldo CE, Oehninger S, Subias E, Mahony M, Alexander NJ, Burkman LJ, Acosta AA 1993 Effect of progesterone on human zona pellucida sperm binding and oocyte penetrating capacity. Fertil Steril 60:137-140
4. Blackmore PF, Beebe S J Danforth D R, Alexander N 1990 Progesterone and 17α-hydroxy-progesterone. Novel stimulators of calcium influx in human spermatozoa. J Biol Chem 265:1376-1380
5. Blackmore PF, Neulin J, Lattanzio F, Beebe SJ 1991 Cell surface binding sites for progesterone mediate calcium uptake in human sperm. J Biol Chem 266:18655-18659
6. 2+ influx. Biochem J 264:539-546
7. Wistrom CA, Meizel S 1993 Evidence suggesting involvement of a unique human sperm steroid receptor/CI channel complex in the progesterone initiated acrosome reaction. Dev Biol 159:679-690
8. A-like receptor is involved in progesterone-induced acrosomal exocytosis in mouse spermatozoa. Biol Reprod 52:373-381
9. Tesarik J, Mendoza C, Moos J, Carreras A 1992 Selective expression of a progesterone receptor on the human sperm surface. Fertil Steril 58:784-792
10. Biggers JD, Whitten WK, Whittingham DG 1971 The culture of mouse embryos in vitro. In: Daniel Jr JC (ed) Methods in Mammalian Embryology. Freeman, San Francisco, pp 86-94
11. Aitken RJ, Clarkson JS 1988 Significance of reactive oxygen species and anti-oxidants in defining the efficacy of sperm preparation techniques. J Androl 9:367-376
12. Aitken RJ 1986 The zona-free hamster oocyte penetration test and the diagnosis of male fertility. Int J Androl [Suppl] 6:1-199
13. Yanagimachi R, Yanagimachi H, Rogers BJ 1976 The use of zona free animal ova as a test system for the assessment of the fertilizing capacity of human spermatozoa. Biol Reprod 15:471-476
14. Aitken RJ, Palerson M, Fisher H, Buckingham DW, van Duin M 1995 Redox regulation of tyrosine phosphorylation in human spermatozoa and its role in the control of human sperm function. J Cell Science 108:2017-2025
15. 2+ are initiated by the zona pellucida during acrosomal exocytosis. Dev Biol 165:152-164
16. Anderson L, Hoyland J, Mason WT, Eidne KA 1992 Characterization of the gonadotrophin-releasing hormone calcium response in single αT3-1 pituitary gonadotroph cells. Mol Cell Endocrinol 86:167-175
17. Anderson L, Alexander CL, Faccenda E, Eidne KA 1995 Rapid desensitisation of the thyrotrophin releasing hormone receptor expressed in single human embryonal kidney 293 cells. Biochem J 311:385-392
18. Fraser LR, McIntyre K 1989 Calcium channel antagonists modulate the acrosome reaction but not capacitation in mouse spermatozoa. J Reprod Fertil 86:223-233
19. Florman HM, Corron ME, Kim TDH, Babcock DF 1992 Activation of voltage sensitive calcium channels of mammalian sperm is required for zona pellucida-induced acrosomal exocytosis. Dev Biol 152:304-314
20. Zheng L, Paik W-Y, Cesnjaj M, Balla T, Tomic M, Catt KJ, Stojilkovic SS 1995 Effects of the phospholipase-C inhibitor, U73122, on signaling and secretion in pituitary gonadotrophs. Endocrinology 136:1079-1088
21. Merritt JE, Armstrong WP, Benham CD, Hallam TJ, Jacob R, Jaxa-Chamiec A, Leigh BK, McCarthy SA, Moores KE, Rink TJ 1990 SK&F, a novel inhibitor of receptor-mediated calcium entry. Biochem J 271:515-522
22. Tesarik J, Carreras A, Mendoza C 1993 Differential sensitivity of progesterone-and zona pellucida- induced acrosome reactions to pertussis toxin. Mol Reprod Dev 34:183-189
23. Blackmore PF, Lattanzio FA 1991 Cell surface localization of a novel nongenomic progesterone receptor on the sperm head. Biochem Biophys Res Commun 181:331-336
24. Aitken RJ, Buckingham DW, Harkiss D, Paterson M, Fisher H, Irvine DS 1996 The extragenomic action of progesterone on human spermatozoa is influenced by redox regulated changes in tyrosine phosphorylation during capacitation. Mol Cell Endocrinol 117:83-93
25. Uhler ML, Leung A, Chan SYW, Wang C 1992 Direct effects of progesterone and antiprogesterone on human sperm hyperactivated motility and acrosome reaction. Fertil Steril 58:1191-1198
26. Brucker C, Kassner G, Loser C, Hinrichsen M, Lipford GB 1994 Progesteroneinduced acrosome reaction: potential role for sperm acrosome antigen-1 in fertilization. Hum Reprod 9:1897-1902
27. Carver-Ward JA, Hollanders JMG, Jaroudi KA, Einspenner M, Al-Sedairy ST, Sheth KV 1996 Progesterone does not potentiate the acrosome reaction in human spermatozoa: flow cytometric analysis using CD46 antibody. Hum Reprod 11:121-126
28. Visconti PE, Bailey JL, Moore GD, Pan D, Olds-Clarke P, Kopf GS 1995 Capacitation of mouse spermatozoa. 1. Correlation between the capacitation state and protein tyrosine phosphorylation. Development 121:1129-1137
29. Meizel S, Turner KO 1991 Progesterone acts at the plasma membrane of human sperm. Mol Cell Endocrinol 11:R1-R5
30. Blackmore PF 1993 Rapid nongenomic actions of progesterone stimulate Ca2+ influx and the acrosome reaction in human sperm. Cell Signal 5:531-538
31. Tesarik J, Moos J, Mendoza C 1993 Stimulation of protein tyrosine phosphorylation by a progesterone receptor on the cell surface of human sperm. Endocrinology 133:328-335
32. Tesarik J, Mendoza C 1992 Defective function of a nongenomic progesterone receptor as a sole sperm anomaly in infertile patients. Fertil Steril 58:793 -797
33. Plant A, McLaughlin EA, Ford WCL 1995 Intracellular calcium measurements in individual human sperm demonstrate that the majority can respond to progesterone. Fertil Steril 64:1213-1215
34. A receptor/chloride channel. Mol Cell Endocrinol 104:237-243
35. Turner KO, Meizel S 1995 Progesterone mediated efflux of cytosolic chloride during the human sperm acrosome reaction. Biochem Biophys Res Commun 213:774-780
36. Turner KO, Garcia MA, Meizel S 1994 Progesterone initiation of the human sperm acrosome reaction: the obligatory increase in intracellular calcium is independent of the chloride requirement. Mol Cell Endocrinol 101:221-225
37. McLaughlin EA, Ford WCL 1994 Effects of cryopreservation on the intracellular calcium concentration of human spermatozoa and its response to progesterone. Mol Reprod Dev 37:241-246
38. Florman HM, Corron ME, Kim TD-H, Babcock DF 1992 Activation of voltagedependent calcium channels of mammalian sperm is required for zona pellucida-induced acrosomal exocytosis. Dev Biol 152:304-314
39. 2+ /ionophore - induced acrosome reaction of mammalian spermatozoa. Biochem J 259:397-406
40. 2+ influx. Biochem J 264:539-546
41. Kopf GS, Woolkalis MJ, Gerton GL 1986 Evidence for a guanine nucleotidebinding regulatory protein in invertebrate and mammalian sperm. J Biol Chem 261:7327-7331
42. Lee MA, Check JH, Kopf GS 1992 A guanine nucleotide-binding regulatory protein in human sperm mediates acrosomal exocytosis induced by the human zona pellucida. Mol Reprod Dev 31:78-86
43. Tesarik J, Mendoza C, Carreras A 1992 Effects of phosphodiesterase inhibitors caffeine and pentoxifylline on spontaneous and stimulus-induced acrosome reactions in human sperm. Fertil Steril 58:1185-1190 Magnification, ×1000