Progesterone does not potentiate the acrosome reaction in human spermatozoa: Flow cytometric analysis using CD46 antibody

Human Reproduction

Volumn 11, Issue 1, 1996, Pages 121-126

  Carver Ward, J A ^a   Hollanders, J M G ^a,b   Jaroudi, K A ^a   Einspenner, M ^a   Al Sedairy, S T ^a   Sheth, K V ^a  

^a KING FAISAL SPECIALIST HOSPITAL AND RESEARCH CENTER   (Saudi Arabia)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Acrosome reaction; CD46; Flow cytometry; Progesterone

Indexed keywords

IONOPHORE; MEMBRANE COFACTOR PROTEIN; PROGESTERONE;

ACROSOME REACTION; ARTICLE; CONTROLLED STUDY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MALE; NORMAL HUMAN; SPERMATOZOON; SPERMATOZOON CAPACITATION; SPERMATOZOON MOTILITY;

EID: 0030029779     PISSN: 02681161     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.humrep.a019003     Document Type: Article

References (54)

1. Aitken, R.J., Ross, A., Hargreave, T., Richardson, D. and Best, F. (1984) Analysis of human sperm function following exposure to the ionophore A23187. J. Androl., 5, 321-329.
2. Aitken, R.J., Buckingham, D.W. and Fang, H.G. (1993) Analysis of the response of human spermatozoa to A23187 employing a novel technique for assessing acrosome reaction. J. Androl., 14, 132-141.
3. Aitken, J., Buckingham, D. and Harkiss, D. (1994) Analysis of the extent to which sperm movement can predict the results of ionophore-enhanved functional assays of the acrosome reaction and sperm-oocyte fusion. Hum. Reprod., 9, 1867-1874.
4. Baldi, E, Casano, R., Falsetti, C., Krausz, C., Maggi, M. and Forti, G. (1991) Intracellular calcium accumulation and responsiveness to progesterone in capacitating human spermatozoa. J. Androl., 12, 323-330.
5. Ballard, L.L., Seya, T., Teckman, J., Lublin, D.M. and Atkinson, J.R (1987) A polymorphism of the complement regulatory protein MCP (membrane cofactor protein or gp45-70). J. Immunol., 138, 3850-3855.
6. Ballard, L.L, Bora, N.S., Yu, G.H. and Atkinson. J.P. (1988) Biochemical characterisation of membrane cofactor protein of the complement system. J. Immunol., 141, 3923-3929.
7. Blackmore, P.F., Beebe, S.J., Danforth, D.R. and Alexander, N. (1990) Progesterone and 17α-hydroxyprogesterone. Novel stimulators of calcium influx in human sperm. J. Biol. Chem., 265, 1376-1380.
8. Brucker, C., Kassner, G., Loser, C., Hinrichsen, M. and Lipford, G.B. (1994) Progesterone-induced acrosome reaction: potential role for sperm acrosome antigen-1 in fertilization. Hum. Reprod., 9, 1897-1902.
9. Calvo, L., Dennison-Lagos, L. Banks, S.M., Fugger, E.F. and Sherins, R.J. (1993) Chemical composition and protein source in the capacitation medium significantly affect the ability of human spermatozoa to undergo follicular fluid induced acrosome reaction. Hum. Reprod., 8, 575-580.
10. Carver-Ward, J.A., Jaroudi, K.A., Einspenner, M., Parhar, R.S., Al-Sedairy, S.T. and Sheth. K V. (1994) Pentoxifylline potentiates ionophore (A23187) mediated acrosome reaction in human sperm, flow cytometric analysis using CD46 antibody. Hum. Reprod. 9, 71-76.
11. Chan, S YW, Tang, L.C.H. and Ma, H.K. (1983) Stimulation of the zonafree hamster ova penetration efficiency by human spermatozoa after 17β-estradiol treatment. Fertil. Steril., 39, 80-84.
12. Cross, N.L., Morales, P., Overstreet, J.W. and Hanson, F.W. (1986) Two simple methods for detecting acrosome-reacted human sperm. Gamete Res., 15, 213-226.
13. Cross, N.L., Morales, P., Overstreet, J.W. and Hanson, F.W. (1988) Induction of acrosome reactions by the human zona pellucida. Biol. Reprod., 38, 235-244.
14. Cummins, J.M., Pember, S M , Jequier, A.M., Yovich, J.L. and Hartmann, P.E. (1991) A test of the human sperm acrosome reaction following ionophore challenge. J. Androl., 12, 98-103.
15. DasGupta, S., O'Toole, C.O., Mills, C.L. and Fraser, L.R. (1994) Effect of pentoxifylline and progesterone on human sperm capacitation and acrosomal exocytosis. Hum. Reprod., 9, 2103-2109.
16. D'Cruz, O.J. and Haas, G.G. (1992) How cytometric quantitation of the expression of membrane cofactor protein as a marker for the human sperm acrosome reaction. Fertil. Steril., 58, 633-636.
17. De Jonge, C.J., Mack, S.R. and Zaneveld, LJ.D. (1989) Synchronous assay for human sperm capacitation and the acrosome reaction. J. Androl., 10, 232-239
18. Dravland, J.E. and Mortimer, D. (1985) A simple discontinuous Percoll gradient procedure for washing human spermatozoa. IRCS Med. Sci., 13, 16-17.
19. 2+ and pH that mediate mammalian sperm acrosomal exocytosis Dev. Biol., 135, 133-146.
20. Gearon, C.M., Mortimer, D., Chapman, M.G. and Forman, R.G. (1994) Artificial induction of the acrosome reaction in human spermatozoa. Hum. Reprod.. 9, 77-82.
21. Gruenrt, J.-H., De Geyter. C. and Nieschlag, E. (1990) Objective identification of hyperactivated human spermatozoa by computerized sperm motion analvsis with the Hamilton-Thorn sperm motility analyzer. Hum. Reprod., 5, 593-599.
22. 2-/ionophore-induced acrosome reaction. Cell. Signal., 2, 277-284.
23. Holden, C.A. and Trounson, A.O. (1991) Staining of the inner acrosomal membrane of human spermatozoa with concanavalin A lectin as an indicator of potential egg penetration ability. Fertil Steril., 56, 967-974.
24. Krausz, C., Gervasi, G., Forti, G. and Baldi. E. (1994) Effect of platelet-activating factor on motility and acrosome reaction of human spermatozoa. Hum. Reprod., 9, 471-476.
25. Kruger, T.F., Menkveld, R., Stander, F.S.H., Lombard, C.J , Van der Merwe, J.P., van Zyl, J.A. and Smith, K. (1986) Sperm morphologic features as a prognostic factor in in vitro fertilization. Fenil. Steril., 46, 1118-1123.
26. Leyton, L. and Saling, P.M. (1989) Evidence that aggregation of mouse sperm receptors by ZP3 triggers the acrosome reaction. J Cell. Biol., 108, 2163-2168.
27. Liszewski, M.K., Post, T.W and Atkinson, J.P. (1991) Membrane cofactor protein (MCP or CD46): newest member of the regulators of complement activation gene cluster. Annu. Rev. Immunol., 9, 431-455.
28. Liu, D.Y. and Baker, H.W.G. (1988) The proportion of sperm with poor morphology but normal intact acrosome detected with Pisum sativum agglutinin and fertilization in vitro. Fertil. Steril., 50, 288-293.
29. Margalioth, E.J., Bronson, R.A., Cooper, G.W. and Rosenfeld, D.L. (1988) Luteal phase sera and progesterone enhance sperm penetration in the hamster egg assay. Fertil Steril. 50, 117-122.
30. Mendoza, C. and Tesarik, J. (1993) A plasma-membrane progesterone receptor in human sperm is switched on by increasing intracellular free calcium. FEBS Lett., 330, 57-60.
31. Modotti, M., Togni, G., Medici, G., Revelli, A., Stamm, J., Piffaretti-Yanez, A., Massobrio, M. and Balema, M. (1994) Effect of peritoneal fluid supplemented with exogenous progesterone on sperm motility in vitro. Hum. Reprod., 9, 303-309.
32. Mortimer, D. and Mortimer, ST. (1988) Influence of system parameter settings on human sperm motility analysis using CellSoft. Hum. Reprod., 3, 621-625.
33. Mortimer, D., Curtis, E.F., Camenzind, A R. and Tanaka, S. (1989) The spontaneous acrosome reaction of human spermatozoa incubated in vitro. Hum. Reprod., 4, 57-62.
34. Oehninger, S., Sueldo, C., Lanzendorf, S., Mahony, M., Burkman, L.J., Alexander, N.J. and Hodgen, G D. (1994a) A sequential analysis of the effect of progesterone on specific sperm functions crucial to fertilization in vitro in infertile patients. Hum. Reprod., 9, 1322-1327.
35. Oehninger, S., Blackmore, P., Morshedi, M., Sueldo, C., Acosta, A.A. and Alexander, N.J. (1994b) Defective calcium influx and acrosome reaction (spontaneous and progesterone-induced) in spermatozoa of infertile men with severe teratozoospermia. Fertil. Steril. 61, 349-354.
36. Osman, R.A., Andria, M.L., Jones, A.D. and Meizel. S. (1989) Steroid induced exocytosis: the human sperm acrosome reaction. Biomed. Biophys. Res. Commun., 160, 828-833.
37. Palermo, G., Joris, H., Devroey, P. and Van Steirteghem, A.C. (1992) Induction of acrosome reaction in human spermatozoa used for subzonal insemination. Hum. Reprod., 7, 248-254
38. Parinaud, J., Labal, B. and Vieitez, G (1992) High progesterone concentrations induce acrosome reaction with a low cytotoxic effect. Fertil. Steril.. 58, 599-602.
39. Quinn, P., Kerin, J.F. and Warnes, G. (1985) Improved pregnancy rate in human in vitro fertilization with the use of a medium based on the composition of human tubal fluid. Fertil. Steril., 44, 493-498.
40. 2+/ionophore-mduced acrosome reaction of mammalian spermatozoa. Biochem. J., 259, 397-406
41. 2+] correlate with the egg penetrating ability of sperm from fertile but not infertile men. Fertil Steril., 60, 526-532.
42. Suarez, S.S., Wolf, O.P. and Meizel, S. (1986) Induction of the acrosome reaction in human spermatozoa by a fraction of human follicular fluid. Gamete Res., 14, 107-121.
43. Takahashi, K., Wetzels, A.M.M., Goverde, H.J.M., Bastiaans, B.A., Janssen, H.J.G. and Rolland, R. (1992) The kinetics of the acrosome reaction of human spermatozoa and its correlation with in vitro fertilization. Hum. Reprod., 7, 889-894
44. Tao, J.. Du, J., Critser, E.S. and Critser. J.K (1993) Assessment of the acrosomal status and viability of human spermatozoa simultaneously using flow, cytometry. Hum. Reprod., 8, 1879-1885.
45. Tesarik, J. (1989) Appropriate timing of the acrosome reaction is a major requirement for the fertilizing spermatozoon. Hum. Reprod., 4, 957-961.
46. Tesarik, J. and Mendoza, C. (1992) Defective function of a nongenomic progesterone receptor as a sole sperm anomaly in infertile patients. Fertil. Steril . 58, 793-797.
47. Tesarik, J., Drahorad, J. and Peknicova, J, (1988) Subcellular immunochemical localization of acrosin in human spermatozoa during the acrosome reaction and zona pellucida penetration. Fertill Sreri, 50, 133-141.
48. 2+ influx. Biochem. J., 264, 539-546.
49. Uhler, M.L., Leung, A, Chan, S Y.W. and Wang, C. (1992) Direct effects of progesterone and antiprogesterone on human sperm hyperactivated motility and acrosome reaction. Fertil. Steril., 58, 1191-1198.
50. Uhler, M.L., Leung, A., Chan, S.Y.W., Schmidt, I. and Wang, C (1993) Assessment of human sperm acrosome reaction by flow cytometry validation and evaluation of the method by fluorescence-activated cell sorting, Fertil. Steril., 60, 1075-1081.
51. Wang, C., Lee, G.S., Leung, A., Surrey, E.S. and Chan, S.Y.W. (1993) Human sperm hyperactivation and acrosome reaction and their relationships to human in vitro fertilization. Fertil. Steril., 59, 1221-1227.
52. Wassarman, P.M. (1987) The biology and chemistry of fertilization. Science. 235, 553-560.
53. Yanagimachi, R. (1988) Mammalian fertilization In On, E., Knobil, E. and Neill. J.D. (eds). Physiology of Reproduction. Vol. A. Raven Press. New York, pp. 135-185.
54. Yudin, A.I., Gottlieb, W. and Meizel, S. (1988) Ultrastructural studies of the early events of the human sperm acrosome reaction as initiated by human follicular fluid. Gamete Res., 20, 11-24.