Second-generation antisense oligonucleotides: Structure-activity relationships and the design of improved signal-transduction inhibitors

Biochemical Society Transactions

Volumn 24, Issue 3, 1996, Pages 630-637

  Altmann, K H ^a   Fabbro, D ^a   Dean, N M ^b   Geiger, T ^a   Monia, B P ^b   Muller M ^a   Nicklin, P ^c  

^a CIBA GEIGY LTD   (Switzerland)

^b ISIS PHARMACEUTICALS   (United States)

^c Department of Toxicology   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; ANTISENSE OLIGONUCLEOTIDE; CGP 69845A; CGP 69846A; CGP 73231A; CGP 75182A; ISIS 3512; ISIS 3521; MESSENGER RNA; OLIGODEOXYNUCLEOTIDE PHOSPHOROTHIOATE; RIBONUCLEASE H; RIBONUCLEOSIDE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; CANCER INHIBITION; CELL CULTURE; CLINICAL TRIAL; CONFERENCE PAPER; DRUG DESIGN; GENE EXPRESSION REGULATION; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA BINDING; RNA CLEAVAGE; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION;

EID: 0029791763     PISSN: 03005127     EISSN: None     Source Type: Journal    
DOI: 10.1042/bst0240630     Document Type: Conference Paper

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