On the mechanism of action of ribonuclease A: Relevance of enzymatic studies with a p-nitrophenylphosphate ester and a thiophosphate ester

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 19, 1996, Pages 10018-10021

  Breslow, Ronald ^a   Chapman Jr , William H ^a  

^a Columbia University ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 NITROPHENYL PHOSPHATE; ORGANOPHOSPHATE; PHOSPHOROTHIOIC ACID DERIVATIVE; RIBONUCLEASE A;

AQUEOUS SOLUTION; ARTICLE; CHEMICAL STRUCTURE; CYCLIZATION; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME MECHANISM; ENZYME SUBSTRATE COMPLEX; HYDROLYSIS; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; STEREOCHEMISTRY;

BINDING SITES; DINUCLEOSIDE PHOSPHATES; ESTERS; HISTIDINE; KINETICS; MODELS, STRUCTURAL; MUTAGENESIS, SITE-DIRECTED; NITROPHENOLS; ORGANOPHOSPHORUS COMPOUNDS; RECOMBINANT PROTEINS; RIBONUCLEASE, PANCREATIC; SUBSTRATE SPECIFICITY; THERMODYNAMICS; THIOPHOSPHORIC ACID ESTERS;

FELIS CATUS;

EID: 0029788628     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.19.10018     Document Type: Article

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