The design of agents to control DNA methylation adducts. Enhanced major groove methylation of DNA by an N-Methyl-N-nitrosourea functionalized phenyl neutral red intercalator

Chemical Research in Toxicology

Volumn 9, Issue 6, 1996, Pages 939-948

  Mehta, Pratibha ^a   Church, Kevin ^b   Williams, Jonathan ^a,c   Chen, Fa Xian ^a   Encell, Lance ^a   Shuker, David E G ^d   Gold, Barry ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b UNIVERSITY OF DAYTON   (United States)

^c ASTON UNIVERSITY   (United Kingdom)

^d UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

INTERCALATING AGENT; METHYLNITROSOUREA; NEUTRAL RED;

ANIMAL CELL; ARTICLE; CIRCULAR DICHROISM; CYTOTOXICITY; DNA METHYLATION; DRUG DESIGN; DRUG DNA INTERACTION; MUTAGENICITY; NONHUMAN; SALMON; SPERM;

ADENINE; CIRCULAR DICHROISM; DNA ADDUCTS; DNA METHYLATION; DRUG DESIGN; ETHIDIUM; GUANINE; INTERCALATING AGENTS; METHYLNITROSOUREA; NEUTRAL RED; SPECTROPHOTOMETRY, ULTRAVIOLET; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0029782740     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx960007n     Document Type: Article

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