Transfer of a foreign gene into the brain using adenovirus vectors

Nature Genetics

Volumn 3, Issue 3, 1993, Pages 224-228

  Akli, Saïd ^a   Caillaud, Catherine ^a   Vigne, Emmanuelle ^b   Stratford Perricaudet, Leslie D ^b   Poenaru, Livia ^a   Perricaudet, Michel ^b   Kahn, Axel ^a   Peschanski, Marc R ^c  

^a INSTITUT COCHIN   (France)

^b INSTITUT GUSTAVE ROUSSY   (France)

^c INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; VIRUS VECTOR;

ADENOVIRUS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN; CENTRAL NERVOUS SYSTEM; CLONING VECTOR; CONTROLLED STUDY; GENE TRANSFER; NONHUMAN; RAT;

ADENOVIRIDAE; ANIMAL; BETA-GALACTOSIDASE; BRAIN; ESCHERICHIA COLI; GENE THERAPY; GENES, BACTERIAL; GENETIC VECTORS; GOLGI APPARATUS; NEURONS; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINATION, GENETIC; SUPPORT, NON-U.S. GOV'T; TRANSFECTION;

ADENOVIRIDAE; ANIMALIA;

EID: 0027408530     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng0393-224     Document Type: Article

References (15)

1. Culver, W. C. et al. In vivo gene transfer with retroviral vector-producer cells for treatment of experimental brain tumors. Science 256, 1550-1552 (1992).
2. Johnson, P. A., Miyanohara, A., Levine, F., Cahill, T. &Friedman, T. Cytotoxicity of a replication defective mutant of herpes simplex virus 1. J. Virol. 66, 2952-2965 (1992).
3. Fink, J. D. et al. In vivo expression of 6-galactosidase in hippocampal neurons by HSV-mediated gene transfer. Hum. Gene Ther. 3, 11-19 (1992).
4. Wolfe, J. H., Deshmane, S. L. & Fraser, N. W. Herpes virus vector gene transfer and expression of 6-glucuronidase in the central nervous system of MPS VII mice. Nature Genet. 1, 379-384 (1992).
5. Quantìn, B., Perricaudet, L. D., Tajbakhsh, S. & Mandel, J. L. Adenovirus as an expression vector in muscle cells in vivo. Proc. natn. Acad. Sci. U. S. A. 89, 2581-2584 (1992).
6. Jaffe, H. A. et al. Adenovirus-mediated in vivo gene transfer and expression in normal rat liver. Nature Genet. 1, 372-378 (1992).
7. Stratford-Perricaudet, L. D., Levrero, M., Chase, J. F., Perricaudet, M. & Briand, P. Evaluation of the transfer and expression in mice of an enzyme-encoding gene using a human adenovirus vector. Hum. Gene Ther. 1, 241-256 (1990).
8. Rosenfeid, M. A. et al. Adenovirus-mediated transfer of a recombinant alpha 1-antitrypsin gene to the lung epithelium in vivo. Science 252, 431-434 (1991).
9. Straus, S. E. Adenovirus infections In Humans, in The Adenoviruses (ed. Ginsberg, H. S.) 451-496 (Plenum Press, New York, 1984)
10. Chanock, R. M., Ludwig, W., Heubner, R. J., Cate, T. R. & Chu, L. -W. Immunization by selective infection with type 4 adenovirus grown in human diploid tissue culture. I. Safety and lack of oncogenicity and tests for potency in volunteers. JAMA 195, 445-452 (1966).
11. Stratford-Perricaudet, L. D., Makeh, I., Perricaudet, M. & Briand, P. Widespread long-term gene transfer to mouse skelet al muscles and heart. J. din. Invest. 90, 626-630 (1992).
12. Kalderon, D" Roberts, B. L., Richardson, W. D. & Smith, A. E. A short amino acid sequence able to specify nuclear location. Cell 39, 499-509 (1984).
13. Ragot, T. et al. Efficient adenovirus-mediated transfer of a human minidystrophin gene to skelet al muscle of mdx mice. Nature (in the press).
14. Rosenfeid, M. A. et al. In vivo transfer of the human cystic fibrosis transmembrane conductance regulator gene to the airway epithelium. Cell 68, 143-155(1992).
15. Sanes, J. R., Rubenstein, J. L. R. & Nicolas, J. F. Use of a recombinant retrovirus to study post-implantation cell lineage in mouse embryos. EMBO J. 5, 3133-3142 (1986).