Molecular basis of T lymphocyte CD4 antigen functions

European Journal of Clinical Chemistry and Clinical Biochemistry

Volumn 34, Issue 9, 1996, Pages 723-728

  Gaubin, Muriel ^a   Autiero, Monica ^a   Houlgatte, Rémi ^a   Basmaciogullari, Stéphane ^a   Auffray, Charles ^a   Piatier Tonneau, Dominique ^a  

^a CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; T LYMPHOCYTE ANTIGEN; T LYMPHOCYTE RECEPTOR;

ANTIGEN FUNCTION; CONFERENCE PAPER; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; VIRUS CELL INTERACTION;

ANTIGENS, CD4; BINDING SITES; HISTOCOMPATIBILITY ANTIGENS CLASS II; HIV ENVELOPE PROTEIN GP120; HIV-1; HUMANS; MODELS, MOLECULAR;

EID: 0029756195     PISSN: 09394974     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (50)

1. Kisielow P, Von Boehmer H. Development and selection of T cells: facts and puzzles. Adv Immunol 1995; 58:87-209.
2. Miceli C, Parnes JR. Role of CD4 and CD8 in T cell activation and differentiation. Adv Immunol 1993; 53:59-123.
3. Sattentau Q, Weiss RA. The CD4 antigen: physiological ligand and H1V receptor. Cell 1988; 52:631-3.
4. Reinherz EL, Kung P, Goldstein G, Schlossman S. Separation of functional subsets of T cells by monoclonal antibodies. Proc Natl Acad Sei USA 1979; 76:4061-5.
5. Biddison WE, Rao PE, Talle MA, Goldstein G, Shaw S. Possible involvement of the OK.T4 molecule in T cell recognition of class II HLA antigens. Evidence from studies of cytotoxic T lymphocytes specific for SB antigens. J Exp Med 1982; 156:1065-76.
6. Marrack P, Endres R, Schimonkevitz R, Zlotnik A, Dialynas D, Fitch F, et al. The major histocompatibility complex-restricted antigen receptor on T cells. II. Role of the L3T4 product. J Exp Med 1983; 158:1077-91.
7. Gay D, Maddon P, Sekaly R, Talle MA, Godfrey M, Long E, et al. Functional interaction between human T-cell protein CD4 and the major histocompatibility complex HLA-DR antigen. Nature (London) 1987; 328:626-9.
8. Veillette A, Bookman MA, Horak EM, Bolen JB. The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p561ck. Cell 1988; 55:301-8.
9. Janeway CA. The role of CD4 in T-cell activation: accessory molecule or co-receptor. Immunol Today 1989; 10:234-8.
10. Mittler RS, Goldman SJ, Spitalny GL, Burakoff SJ. T-cell receptor-CD4 physical association in a murine T-cell hybridoma: induction by antigen receptor ligation. Proc Natl Acad Sei USA 1989; 86:8431-5.
11. Doyle C, Strominger JL. Interaction between CD4 and class II MHC molecules mediates cell adhesion. Nature (London) 1987; 330:256-9.
12. Cammarota G, Scheirle A, Takacs B, Doran DM; Knorr R, Bannwarth W, et al. Identification of a CD4 binding site on the 2 domain of HLA-DR molecules. Nature (London) 1992; 356:799-801.
13. König R, Huang LY, Germain RN. MHC class II interaction with CD4 mediated by a region analogous to the MHC class 1 binding site for CDS. Nature 1992; 356:796-8.
14. Chuck RS, Cantor CR, Tse DB. CD4-T-cell antigen receptor complexes on human leukemia T cells. Proc Natl Acad Sei USA 1990; 87:5021-5.
15. Anderson P, Blue ML, Morimoto C, Schlossman SF. Crosslinking of T3 (CD3) with T4 (CD4) enhances the proliferation of resting T lymphocytes. J Immunol 1987; 139:678-82.
16. Weiss A, Littman DR. Signal transduction by lymphocyte antigen receptors. Cell 1994; 76:263-74.
17. Newell MK, Haughn LJ, Maroun CR, Julius MH. Death of mature T cells by separate ligation of CD4 and the T-cell receptor for antigen. Nature (London) 1990; 347:286-9.
18. Mazerolles F, Auffray C, Fischer A. Down regulation of T cell adhesion by CD4. Hum Immunol 1991; 31:40-6.
19. Fauci A. Multifactorial nature of human immunodeficiency virus disease: implications for therapy. Science 1993; 262:1011-8.
20. Soula M, Fagard R, Fischer S. Interaction of human immunodeficiency virus glycoprotein gp!60 with CD4 in Jurkat cells increases p561ck autophosphorylation and kinase activity. Int Immunol 1992; 4:295-9.
21. Corado J, Mazerolles F, Le Deist F, Barbat C, Kaczorek M, Fischer A. Inhibition of CD4-positive T cell activation and adhesion by peptides derived from the binding site of gp 160 to CD4. J Immunol 1991; 147:4756-62.
22. Di Somma MM, Nuti S, Telford JL, Baldari CT. p561ck plays a key role in transducing apoptotic signals in T cells. FEBS Letters 1995; 363:101-4.
23. Baldari CT, Milia E, Di Somma MM, Baldoni F, Valitutti S, Telford JL. Distinct signaling properties identify functionally different epitopes. Eur J Immunol 1995; 25:1843-50.
24. Benkirane M, Corbeau P, Housset V, Devaux C. An antibody that binds the immunoglobulin CDR3-like region of the CD4 molecule inhibits provirus transcription in HIV-infected T cells. EMBO J 1993; 12:4909-21.
25. Benkirane M, Hirn M, Carrière D, Devaux C. Functional epitope analysis of the human CD4 molecule: antibodies that inhibit human immunodeficiency virus type 1 gene expression bind to the immunoglobulin CDR3-like region of CD4. J Virol 1995; 69:6898-903.
26. Maddon PJ, Littman DR, Godfrey M, Maddon DE, Chess L, Axel R. The isolation and nucleotide sequence of a cDNA encoding the T cell surface protein T4: a new member of the immunoglobulin gene family. Cell 1985; 42:93-104.
27. Kwong PD, Ruy SE, Hendrickson WA, Axel R, Sweet RM, Folena-Wassermann G, et al. Molecular characteristics of recombinant human CD4 as deduced from polymorphic crystals. Proc Natl Acad Sei USA 1990; 87:6423-7.
28. Ryu SE, Kwong PD, Truneh A, Porter TG, Arthos J, Rosenberg M, et al. Crystal structure of an HIV-binding recombinant fragment of human CD4. Nature (London) 1990; 348:419-26.
29. Wang J, Yan Y, Garett TPJ, Liu J, Rodgers DW, Garlick RL, et al. Atomic structure of a fragment of human CD4 containing two immunoglobulin-like domains. Nature (London) 1990; 348:411-8.
30. Brady RL, Dodson EJ, Dodson GG, Lange G, Davis SJ, Williams AF, et al. Crystal structure of domains 3 and 4 of rat CD4: relation to the NH2-terminal domains. Science 1993; 260:979-83.
31. Bour S, Geleziunas R, Wainberg MA. The human immunodeficiency virus type l (HIV-1) CD4 receptor and its central role in promotion of HIV-1 infection. Microbiol Reviews 1995; 59:63-93.
32. Bowman MR, MacFerrin KD, Schreiber SL, Burakoff SJ. Identification and structural analysis of residues in the V1 region of CD4 involved in interaction with human immunodeficiency virus envelope glycoprotein gp!20 and class II major histocompatibility complex molecules. Proc Natl Acad Sei USA 1990; 87:9052-6.
33. Piatier-Tonneau D, Gastinel LN, Moussy G, Bénichou B, Amblard F, Vaigot P, et al. Mutations in the D strand of the human CD4 VI domain affect CD4 interactions with the human immunodificiency virus envelope glycoprotein gp!20 and HLA class II antigens similarly. Proc Natl Acad Sei USA 1991; 88:6858-62.
34. Houlgatte R, Scarmato P, El Marhomy S, Martin M, Ostankovitch M, Lafosse S, et al. HLA class II antigens and the human immunodeficiency virus envelope glycoprotein gp!20 bind to the same face of CD4. J Immunol 1994; 152:4475-88.
35. Clayton LK, Sieh H, Pious DA, Reinherz EL. Identification of human CD4 residues affecting class II MHC versus HIV gp 120 binding. Nature (London) 1989; 339:548-51.
36. Moebius U, Clayton LK, Abraham S, Diener A, Yunis JJ, Harrison SC, et al. Human immunodeficiency virus gp!20 binding C'C ridge of CD4 domain 1 is also involved in interaction with class II major histocompatibility complex molecules. Proc Natl Acad Sei USA 1992; 89:12008-12.
37. Moebius U, Pallai P, Harrison SC, Reinherz EL. Delineation of an extended surface contact area on human CD4 involved in class II major histocompatibility complex binding. Proc Natl Acad Sei USA 1993; 90:8259-63.
38. Lamarre D, Ashkenazi A, Fleury S, Smith DH, Sekaly RP, Capon DJ. The MHC-binding and gp!20-binding functions of CD4 are separable. Science 1989; 245:743-6.
39. Fleury S, Lamarre D, Meloche S, Ryu SE, Cantin C, Hendrickson WA, et al. Mutational analysis of the interaction between CD4 and class II MHC: class II antigens contact CD4 on a surface opposite the gp!20-binding site. Cell 1991; 66:1037-49.
40. Langedijk JPM, Puijk WC, van Horn WP, Meloen RH. Location of CD4 dimerization site explains critical role of CDR3like region in HIV-1 infection and T-cell activation and implies a model for complex of coreceptor-MHC. J Biol Chem 1993; 268:16875-8.
41. Sakihama T, Smolyar A, Reinherz EL. Oligomerization of CD4 is required for stable binding to class II major histocompatibility complex proteins but not for interaction with human immunodeficiency virus gp!20. Proc Natl Acad Sei USA 1995; 92:6444-8.
42. Autiero M, Houlgatte R, Martin M, Auffray C, Guardiola J, Piatier-Tonneau D. Competition of HLA-DR and a 2 domain peptide for human immunodeficiency virus envelope glycoprotein gp!20 binding to CD4. Int Immunol 1995; 7:191-7.
43. Piatier-Tonneau D, Gastinel LN, Amblard F, Wojcik M, Vaigot P, Auffray C. Interaction of CD4 with HLA class II antigens and HIV gp!20. Immunogenetics 1991; 34:121-8.
44. Brown JH, Jardetzky TS, Gorga JC, Stern LJ, Urban RG, Strominger JL, et al. Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1. Nature (London) 1993; 364:33-9.
45. König R, Shen X, Germain RN. Involvement of both major histocompatibility complex class II a and chains in CD4 function indicates a role for ordered oligomerization in T cell activation. J Exp Med 1995; 182:779-87.
46. Schafer PH, Pierce SK. Evidence for dimers of MHC class II molecules in B lymphocytes and their role in low affinity T cell responses. Immunity 1994; 1:699 -707.
47. Field B, Ober B, Malchiodi E, Lebedeva M, Braden B, Ysern X, et al. Crystal structure of the Va domain of a T cell antigen receptor. Science 1995; 270:1821-4.
48. Cassait DR, Truneh A. Immunization with soluble murine CD4 without causing impairment of immune function. J Immunol 1991; 147:1470-6.
49. Zhang X, Piatier-Tonneau D, Auffray C, Murali R, Mahapatra A, Zhang F, et al. Synthetic CD4 exocyclic peptides antagonize CD4 holoreceptor binding and T cell activation. Nature Biotechnology 1996; 14:472-5.
50. Kraulis PJ. MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures. J Appl Crystallogr 1991; 24:946-50.