Noninvasive quantification of regional myocardial metabolic rate of oxygen by 15O2 inhalation and positron emission tomography: Experimental validation

Circulation

Volumn 94, Issue 4, 1996, Pages 808-816

  Yamamoto, Yusuke ^a   De Silva, Ranil ^a   Rhodes, Christopher G ^a   Iida, Hidehiro ^a   Lammertsma, Adriaan A ^a   Jones, Terry ^a   Maseri, Attilio ^a  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

Author keywords

metabolism; myocardium; oxygen; tomography

Indexed keywords

ADENOSINE; CARBON DIOXIDE; CARBON MONOXIDE; ISOPRENALINE; MORPHINE; OXYGEN 15; PROPRANOLOL;

ANIMAL EXPERIMENT; ARTERIAL BLOOD; ARTICLE; AUTORADIOGRAPHY; CARBON DIOXIDE EXCRETION; CONTROLLED STUDY; CORONARY SINUS BLOOD FLOW; DOG; HEART MUSCLE OXYGEN CONSUMPTION; HEMODYNAMICS; METABOLIC RATE; NONHUMAN; OXYGEN BREATHING; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL;

EID: 0029737631     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.94.4.808     Document Type: Article

References (29)

1. Chapman JB. Energy sources of cardiac contraction: the myocardium. Adv Cardiol. 1974;12:128-138.
2. Phelps ME, Mazziotta JC, Schelbert HR. Positron Emission Tomography and Auto radiography: Principles and Applications for the Brain and the Heart. New York, NY: Raven Press; 1986.
3. Schon HR, Schelbert HR, Najafi A, Robinson G, Huang SC, Banio J, Phelps ME. C-11 labeled palmitic acid for the noninvasive evaluation of regional myocardial fatty acid metabolism with positron emission tomography, 1: kinetics of C-11 palmitic acid in normal myocardium. Am Heart J. 1982;103:532-547.
4. Buxton DB, Schwaiger M, Nguyen A, Phelps ME, Scheibert HR. Radiolabelled acetate as a tracer of myocardial tricarboxylic acid cycle flux. Circ Res. 1988;63:628-634.
5. Brown M, Marshall DR, Sobel BE, Begmann SR. Delineation of myocardial oxygen utilization with carbon-11-labeled acetate. Circulation. 1987;76:687-696.
6. Brown MA, Myears DW, Bergmann SR. Noninvasive assessment of canine myocardial oxidative metabolism with carbon-11 acetate and positron emission tomography. J Am Coll Cardiol. 1988;12:1054-1063.
7. 11C]-acetate and dynamic positron emission tomography. Circulation. 1989;79:134-142.
8. 11C] acetate as a tracer for noninvasive assessment of oxidative metabolism with positron emission tomography in normal, ischemic, postischemic, and hyperemic canine myocardium. Circulation. 1990;81: 1594-1605.
9. Buck A, Wolpers G, Hutchins GD, Savas V, Mangner TJ, Nguyen N, Schwaiger M. Effect of carbon-11 acetate recirculation on estimates of myocardial oxygen consumption by PET. J Nucl Med. 1991;32:1950-1957.
10. Henes CG, Bergmann SR, Walsh MN, Sobel BE, Geltman EM. Assessment of myocardial oxidative metabolic reserve with positron emission tomography and carbon-11 acetate. J Nucl Med. 1989; 30:1489-1499.
11. Walsh MN, Geltman EM, Brown MA, Henes CG, Weinheimer CJ, Sobel BE, Bergmann SR. Noninvasive estimation of regional myocardial oxygen consumption by positron emission tomography with carbon-11 acetate in patients with myocardial infarction. J Nucl Med. 1989;30:1798-1808.
12. 11C] acetate and dynamic positron emission tomography. Circulation. 1989;80:863-872.
13. 2 inhalation and positron emission tomography. Circulation. 1990;82(suppl III):III-614. Abstract.
14. 2 inhalation and positron emission tomography: theory, error analysis, and application in humans. Circulation. 1996;94:792-807.
15. Spinks TJ, Araujo LI, Rhodes CG, Hutton BF. Physical aspects of cardiac scanning with a block detector positron emission tomography. J Comput Assist Tomogr. 1991;15:893-904.
16. Spinks TJ, Jones T. Gilardi MC, Heather JD. Physical performance of the latest generation of commercial positron scanner. IEEE Trans Nucl Sci. 1988;35:721-725.
17. Araujo LI, Lammertsma AA, Rhodes CG, McFalls EO, Iida H, Rechavia E, Galassi AR, De Silva R, Jones T, Maseri A. Noninvasive quantification of regional myocardial blood flow in coronary artery disease with oxygen-15 labeled carbon dioxide inhalation and positron emission tomography. Circulation, 1991;83:875-885.
18. Heymann MA, Payne BD, Hoffman JIE, Rudolph AM. Blood flow measurements with radionuclide labeled particles. Prog Cardiovasc Dis. 1977;20:55-79.
19. Wallenstein S, Zucker CL, Fleiss JL. Some statistical methods useful in circulation research. Circ Res. 1980;47:639-652.
20. Messer JV, Wagman RJ, Levine HJ, Neill WA, Krasnow N, Gorlin R. Patterns of human myocardial oxygen extraction during rest and exercise. J Clin invest. 1962;41:725-735.
21. Leight L, DeFazio V, Turners FN, Regan TJ, Hellmens HK. Coronary blood flow, myocardial oxygen consumption and myocardial metabolism in normal and hyperthyroid human subjects. Circulation. 1956;14:90-99.
22. Klocke FJ, Kaiser GA, Ross J Jr, Braunwaid E. An intrinsic adrenergic vasodilator mechanism in the coronary vascular bed of the dog. Circ Res. 1965;16:376-382.
23. Crystal GJ, Downey HF, Bashour HF. Small vessel and total coronary blood volume during intracoronary adenosine. Am J Physiol. 1981; 241:H194-H201.
24. Parsons WJ, Rembert JC, Bauman RP, Duhaylongsod FG, Greenfield JC, Piantadosi CA. Myocardial oxygenation in dogs during partial and complete coronary artery occlusion. Circ Res. 1993; 73:458-464.
25. Gropler RJ, Siegel BA, Sampathkumaran K, Perez J, Sobel BE, Bergmann SR, Geltman EM. Dependence of recovery of contractile function on maintenance of oxidative metabolism after myocardial infarction. J Am Coll Cardiol. 1992;19:989-997.
26. Weiss HR, Sinha AK. Regional oxygen saturation of small arteries and veins in the canine myocardium. Circ Res. 1978;42: 119-126.
27. Weiss HR, Neubauer JA, Lipp JA, Sinha AK. Quantitative determination of regional oxygen consumption in the dog heart. Circ Res. 1978;42:394-401.
28. 15O-hemoglobin. Circ Res. 1978;42:511-518.
29. 2. J Nucl Med. 1991; 32(suppl):988. Abstract.