Mild temperature hyperthermia combined with carbogen breathing increases tumor partial pressure of oxygen (pO2) and radiosensitivity

Cancer Research

Volumn 56, Issue 24, 1996, Pages 5590-5593

  Griffin, Robert J ^a   Okajima, Kaoru ^a   Barrios, Bennett ^a   Song, Chang W ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOGEN; OXYGEN;

ANIMAL CELL; ARTICLE; BATH; CARBON DIOXIDE BREATHING; CELL SURVIVAL; CONTROLLED STUDY; FEMALE; FIBROSARCOMA; HYPERTHERMIC THERAPY; MOUSE; NONHUMAN; OXYGEN BREATHING; OXYGEN TENSION; PRIORITY JOURNAL; RADIOSENSITIVITY; X IRRADIATION;

ANIMALS; CARBON DIOXIDE; CELL HYPOXIA; FIBROSARCOMA; HUMANS; HYPERTHERMIA, INDUCED; MICE; NEOPLASMS; OXYGEN; PARTIAL PRESSURE; RADIATION-SENSITIZING AGENTS; TUMOR CELLS, CULTURED;

EID: 0029730699     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Song, C. W., Shakil, A , Osborn, J L., and Iwata, K. Tumor oxygenation is increased by hyperthermia at mild temperatures. Int. J. Hyperthermia, 12: 367-373, 1996
2. 2 can be increased markedly by mild hyperthermia. Br. J. Cancer, 74 (Suppl.): 217s-221s, 1996.
3. Song, C. W Effect of local hyperthermia on blood flow and microenvironment. Cancer Res , 44 (Suppl.); 4721s-4730s, 1984.
4. Durand, R. E Potentiation of radiation lethality by hyperthermia in a tumor model: effects of sequence, degree, and duration of heating. Int. J. Radiat. Oncol. Biol. Phys., 4: 401-405, 1978
5. Lepock, J., Cheng, K. H., Al-Qyst, H., Sim, I , Koch, C J., and Kruuv, J Hyperthermia-induced inhibition of respiration and mitochondrial protein denaturation in CHL cells Int. J Hyperthermia. 3: 123-132, 1987.
6. Oleson, J R. Hyperthermia from the clinic to the laboratory: a hypothesis (Eugene Robinson Special Lecture). Int J. Hyperthermia, 11: 315-322, 1995.
7. Koch, C. J., Evans, S. M., and Lord, E M Comment on the hypothesis that hyperthermia facilitates reoxygenation Int. J. Hyperthermia. 11: 447-450, 1995.
8. Rubin, R , Hanley, J , Keys, H M , Marcial, V , and Brady. L Carbogen breathing during radiation therapy, the Radiation Therapy Oncology Group study. Int. J. Radiat Oncol. Biol Phys. , 5 1963-1970, 1979
9. Chaplin, D G , Horsman, M R., and Siemann, D. W. Further evaluation of nicotinamide and carbogen as a strategy to reoxygenate hypoxic cells in vivo importance of nicotinamide dose and pre-irradiation breathing time. Br. J Cancer. 68: 269-273, 1993
10. 2 and radiosensitivity in three tumour lines. Int J Radiat. Biol. 65: 379-386, 1994.
11. Rojas, A M., Hirst, V K , Calvert, A. S., and Johns, H Carbogen and nicotinamide as radiosensitizers in a murine mammary carcinoma using conventional and accelerated radiotherapy. Int. J. Radiat Oncol. Biol. Phys., 34: 357-365, 1996.
12. Saunders, M., and Dische, S. Clinical results of hypoxic cell radiosensitization from hyperbaric oxygen to accelerated radiotherapy, carbogen and nicotinamide Br. J. Cancer, 74 (Suppl.): 271s-278s, 1996.
13. Song, C. W., Kim, G E., Lyons, J L., Makepeace, C. M., Griffin, R. J., Rao, G. H., and Cragoe, E. J., Jr. Thermosensitization by increasing intracellular acidity with amiloride and its analogs. Int. J Radiat. Oncol. Biol. Phys., 30: 1161-1169, 1994.
14. 2 histography. Br. J. Cancer, 12: 919-924, 1992.
15. Inch, W. R., McCredie, J. A , and Sutherland, R. M. Effect of duration of breathing 95% oxygen plus 5% carbon dioxide before X-irradiation on cure of C3H mammary tumour Cancer (Phila.), 25: 926-931, 1970.
16. Horsman, M. R., Khalil, A. A., Siemann, D. W , Grau, C , Hill, S. A., Lynch, E. M., Chaplin, D. J., and Overgaard, J. Relationship between radiobiological hypoxia in tumors and electrode measurements of tumor oxygenation. Int. J Radiat Oncol. Biol. Phys. 29: 439-442, 1994.
17. Sasai, K., and Brown, J. M Discrepancies between measured changes of radiobiological hypoxic fraction and oxygen tension monitoring using two assay systems. Int J. Radiat Oncot Biol. Phys , 30: 335-361, 1994.
18. 3H]misonidazole binding, and paired survival assay. Radiat Res., 145: 491-500, 1996.
19. Fenton, B. M., and Siemann, D W. Are direct measures of tumor oxygenation reflective of changes in tumor radiosensitivity following oxygen manipulation? Acta Oncol , 34: 307-311, 1995.
20. Olch, A. J , Kaiser, L. R., Silberman, A W., Storm, F. K., Graham, L. S., and Morton, D. L. Blood flow in human tumors during hyperthermia therapy: demonstration of vasoregulation and an applicable physiological model J Surg. Oncol , 23: 125-132, 1983