Glu227→Lys substitution in the acidic loop of major histocompatibility complex class I α3 domain distinguishes low avidity CD8 coreceptor and avidity-enhanced CD8 accessory functions

Journal of Experimental Medicine

Volumn 184, Issue 5, 1996, Pages 1671-1683

  Shen, Lianjun ^a   Potter, Terry A ^b,c   Kane, Kevin P ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b NATIONAL JEWISH MEDICAL AND RESEARCH CENTER   (United States)

^c UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; CORE PROTEIN; GLUTAMIC ACID; H2 ANTIGEN; HLA ANTIGEN CLASS 1; HYBRID PROTEIN; LIGAND; LYMPHOCYTE ANTIGEN RECEPTOR; LYSINE; NUCLEOPROTEIN (366 374), INFLUENZA VIRUS; NUCLEOPROTEIN (366-374), INFLUENZA VIRUS; PEPTIDE FRAGMENT;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANTIGEN BINDING; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; MAJOR HISTOCOMPATIBILITY COMPLEX; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; T LYMPHOCYTE ACTIVATION; BINDING SITE; CELL ADHESION; CELL CLONE; COMPARATIVE STUDY; CYTOTOXICITY; DEGRANULATION; GENETICS; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; MUTATION; PROTEIN CONFORMATION; SIGNAL TRANSDUCTION;

ANTIGENS, CD8; BINDING SITES; CELL ADHESION; CELL DEGRANULATION; CLONE CELLS; CYTOTOXICITY, IMMUNOLOGIC; GLUTAMIC ACID; H-2 ANTIGENS; HISTOCOMPATIBILITY ANTIGENS CLASS I; LIGANDS; LYMPHOCYTE ACTIVATION; LYSINE; MUTATION; PEPTIDE FRAGMENTS; PROTEIN CONFORMATION; RECEPTORS, ANTIGEN, T-CELL; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, CYTOTOXIC; VIRAL CORE PROTEINS;

EID: 0029661944     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.184.5.1671     Document Type: Article

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