Effects of degree of cell-cell contact on liver specific functions of rat primary hepatocytes

Biotechnology and Bioprocess Engineering

Volumn 5, Issue 2, 2000, Pages 99-105

  Yang, Sung Mun ^a   Lee, Doo Hoon ^a   Park, Jung Keug ^a  

^a Dongguk University   (South Korea)

Author keywords

Alginate; Cell cell interaction; Collagen; Hepatocyte aggregate; Hepatocyte spheroid

Indexed keywords

EID: 0013367824     PISSN: 12268372     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02931879     Document Type: Article

References (33)

1. Moslen, M. T (1996) Toxic responses of the liver, pp. 403-416. In: C. D. Klaassen, M. O. Amdur, and J. Doull (eds). Casarett and Doull's Toxicology: The Basic Science of Poisons. 5th ed. McGraw-Hill, New York, USA.
2. Jauregui, H. O., C. J.-P. Mullon, and B. A. Solomon (1997) Extracorporeal artificial liver support, pp. 463-479. In: R. P. Lanza, R. Langer, and W. L. Chick (ed). Principles of Tissue Engineering. Academic Press, San Diego, California.
3. Langer, R. and J. P. Vacanti (1993) Tissue engineering. Science 260: 920-926.
4. Kamlot, A., J. Rozga, E D. Watanabe, and A. A. Demetriou (1996) Review: Artificial liver support systems. Biotechnol. Bioeng 50: 382-391.
5. Reid, L. M., A. S. Fiorino, S. H. Sigal, S. Brill, and P. A. Hoist (1992) Extracellular matrix gradients in the space of disse: Relevance to liver biology. Hematology 15: 1198-1203.
6. Spray, D. C., J. C. Saez, E. L. Hertzberg, and R. Dermietzel (1994) Gap junctions in liver: composition, function, and regulation, pp. 951-967. In I. M. Arias, J. L. Boyer, N. Fausto, W B. Jakoby, D. Schachter, and D. A. Shafritz (ed). The IJver Biology and Pathobiology. 3rd ed. Raven Press, New York.
7. Steer, C. J. (1995) Liver regeneration. FASEB J. 9: 1396-1400.
8. Dunn, J. C. Y., R. G. Tompkins, and M. L. Yarmush (1991) Long-term in vitro function of adult hepatocytes in a collagen sandwich configuration. Biotechnol. Prog. 7: 237-245.
9. Michalopoulos, G. K. (1990) Liver regeneration: molecular mechanism of growth control. FASEB J. 4: 176-187.
10. Arterburn, L. M., J. Zurlo, J. D. Yager, R. M. Overton, and A. H. Heifetz (1995) A morphological study of differentiated hepatocytes in vitro. Hepatology 21: 175-187.
11. Suzuki M., K. Ichikawa, A. Sakoda, and Y. Sakai (1993) Long-term culture of primary rat hepatocytes with high albumin secretion using membrane-supported collagen sandwich. Cytotechnology 11: 213-218.
12. Koebe, H. C., S. Pahernik, P. Eyer, and F. W. Schildberg (1994) Collagen gel immobilization: a useful cell culture technique for long-term metabolic studies on human hepatocytes. Xenobiotica 24: 95-107.
13. Shimbara, N., R. Atawa, M. Takashina, K. Tanaka, and A. Ichihara (1996) Long-term culture of functional hepatocytes on chemically modified collagen gels. Cytotechnology 21:31-43.
14. Kim, S. P., D. H. Lee, and J. K. Park (1998) Development of hepatocyte spheroids immobilization technique using alternative encapsulation method. Biotechnol. Bioprocess Eng 3: 96-102.
15. Nishikawa, Y., Y. Tokusashi, T. Kadohama, H. Nishimori, and K. Ogawa (1996) Hepatocytic cells form bile duct-like structures within a three-dimensional collagen gel matrix. Exp. Cell Res. 223: 357-371.
16. Lin, K. H., H. Hino, S. Maeda, H. Inagaki, J. V. Airat, and T. Saito (1995) Albumin synthesis by rat hepatocytes cultured on collagen gels is sustained specifically by heparin. Exp. Cell Res. 219:717-721.
17. Koide, N., and T. Tsuji (1990) Formation of multicellular spheroids composed of adult rat hepatocytes in dishes with positively charged surfaces and under other nonadherent environments. Exp. Cell Res. 186: 227-235.
18. Lazar, A., M. V. Peshwa, F. J. Wu, C.-M. Chi, F. B. Cerra, and W-S. Hu (1995) Formation of porcine hepatocyte spheroids for use in a bioartificial liver. Cell Transplant. 4: 259-268.
19. Lee, D. H., J. N. Ryu, E. K. Yang, M. K. Chung, S. N. Park, and J. K. Park (1997) Spheroid culture of primary rat hepatocytes in spinner vessel. Korean J. Biotech. Bioeng. 12: 449-455.
20. Guguen-Guillouzo, C., B. Clement, G. Baffet, C. Beaumont, E. Morel-Chany, and D. Glaise (1983) Maintenance and reversibility of active albumin secretion by adult rat hepatocytes co-cultured with another liver epithelial cell type. Exp. Cell Res. 143:47-54.
21. Matsushita, T., H. Ijima, N. Koide, and K. Funatsu (1991) High albumin production by multicellular spheroids of adult rat hepatocytes formed in the pores of polyurethane foam. Appl. Microbiol. Biotechnol. 36: 324-326.
22. Ahn, J. I., D. H. Lee, Y. S. Lee, J. S. Lee, Y. S. Choi, and J. K. Park (1998) Formation of spheroids of adult rat primary hepatocytes in polyurethane foam. J. KOSOMBE 19: 215-223.
23. Patricia A. P.-W and W. M. Saltzman (1993) Growth versus function in the three-dimensional culture of single and aggregated hepatocytes within collagen gels. Biotechnol. Prog. 9: 600-607.
24. Surapaneni, S., T. Pryor, M. D. Klein, and H. W. T. Matthew (1997) Rapid hepatocyte spheroid formation: Optimization and long term function in perfused microcapsules. ASAIO Journal 43: M848-M853.
25. Seglen, P. O. (1978) Preparation of rat liver cells, pp. 29-83. In: D. M. Prescott (ed). Method in Cell Biology. 13. Academic Press, New York, USA.
26. Guguen-Guillouzo, C. (1982) High yield preparation of isolated human adult hepatocytes by enzymatic of the-liver. Cell Biol. Int. Rep. 6: 625-628.
27. Mosmann, T (1983) Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Meth. 65: 55-63.
28. Florence, J. Wu, J. R. Friend, D. D. Hsiao, M. J. Ziiliox, W J. Ko, E B. Cerra, and W S. Hu (1996) Efficient Assembly plications. Biotechnol. Bioeng. 50: 404-415.
29. Madhusudan, V. Peshwa, Y. S. Kyung, D. B. McClure, and W. S. Hu (1993) Cultivation of mammalian cells as aggregates in bioreactors: Effect of calcium concentration on spatial distribution of viability. Biotechnol. Bioeng. 41: 179-187.
30. Ben-Ze'ev, A., G. S. Robinson, N. L. R. Bucher, S. R. Farmer (1988) Cell-cell and cell-matrix interactions differentially regulate the expression of hepatic and cytoskeletal-genes in primary cultures of rat hepatocytes. Proc. Natl. Acad. Sci. USA Cell Biology 85: 2161-2165.
31. Bissell, D. M., D. M. Arenson, J. J. Maher, and F. J. Roll (1987) Support of cultured hepatocytes by a laminin-rich gel. J. Clin. Invest. 79:801-812.
32. Sheil, A. G. R., J. Sun, D. C. Mears, M. Waring, K. Woodman, B. Johnston, M. Horvat, K. J. Watson, N. Koutalistras and L-S. Wang (1996) Preclinical trial of a bioartificial liver support system in a porcine fulminant hepatic failure model. Aust. N. Z.J. Surg. 66: 547-552.
33. Demetriou, A. A., J. Roaga, L. Podesta, E. Lepage, E. Morsiani, A. D. Moscioni, A. Hoffman, M. McGrath, L. Kong, H. Rosen, F. Villamil, G. Woolf, J. Vierling, and L. Makowka (1995) Early clinical experience with a hybrid bioartificial liver. Scand. J. Gastroenterol. 30: Suppl. 208: 111-117.