Solid-Phase synthesis of 2,4,6-trisubstituted pyridines

Journal of Combinatorial Chemistry

Volumn 1, Issue 1, 1999, Pages 73-77

  Chiu, Chingfan ^a   Tang, Zhilian ^a   Ellingboe, John W ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0013210361     PISSN: 15204766     EISSN: None     Source Type: Journal    
DOI: 10.1021/cc980005g     Document Type: Article

References (11)

1. Hermkens, P. H. H.; Ottenheijm, H. C. J.; Rees, D. Solid-Phase Organic Reactions: A Review of the Recent Literature. Tetrahedron 1996, 52, 4527-4554.
2. Hermkens, P. H. H.; Ottenheijm, H. C. J.; Rees, D. Solid-Phase Organic Reactions II: A Review of the Literature Nov 95-Nov 96. Tetrahedron 1997, 53, 5643-5678.
3. Gordeev, M. F.; Patel, D. V.; Wu, J.; Gordon, E. M. Approaches to Combinatorial Synthesis of Heterocycles: Solid-Phase Synthesis of Pyridines and Pyrido[2,3-d]pyrimidines. Tetrahedron Lett. 1996, 37, 4643-4646.
4. Karle, J. M.; Karle, I. L. Crystal and Molecular Structure of the Antimalarial Agent Enpiroline. Antimicrob. Agents Chemother. 1989, 33, 1081-1089.
5. Marzinzik, A. L.; Felder, E. R. Key Intermediates in Combinatorial Chemistry: Access to Various Heterocycles from α,β-Unsaturated Ketones on the Solid Phase. J. Org. Chem. 1998, 63, 723-727.
6. Powers, D. G.; Casebier, D. S.; Fokas, D.; Ryan, W. J.; Troth, J. R.; Coffen, D. L. Automated Parallel Synthesis of Chalcone-Based Screening Libraries. Tetrahedron 1998, 54, 4085-4096.
7. Katritzky, A. R. Handbook of Heterocyclic Chemistry; Pergamon Press: Oxford, 1985; pp 408-409.
8. Krohnke, F. The Specific Synthesis of Pyridines and Oligopyridines. Synthesis 1976, 1-24.
9. Collini, M. D.; Ellingboe, J. W. The Solid-Phase Synthesis of Trisubstituted Indoles. Tetrahedron Lett. 1997, 38, 7963-7966.
10. Drewes, S. E.; Hogan, C. J.; Kaye, P. T.; Roos, G. H. P. Medicinal Plants of Southern Africa. Part 4. Synthesis of Brackenin-like Molecules from 1,4-Dicarbonyl Precursors and by Oxidative Coupling. X-ray Molecular Structure of Racemic-2,3-Dibenzyl-1,4-diphenylbutane-1,4-dione. J. Chem. Soc., Perkin Trans. 1. 1989, 1585-1591.
11. Akiba, K.; Iseki, Y.; Wada, M. Facile Synthesis of 4-Substituted Pyridines Using Grignard Reagents. Tetrahedron Lett. 1982, 23, 3935-3936.