Platelet-activating factor: A new target site for the development of nootropic agents

Drugs of the Future

Volumn 26, Issue 9, 2001, Pages 883-888

  Singh, Manjeet ^a   Saraf, Manish Kumar ^a  

^a PUNJABI UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0013156834     PISSN: 03778282     EISSN: None     Source Type: Journal    
DOI: 10.1358/dof.2001.026.09.703561     Document Type: Article

References (92)

1. Wang, J.H., Ko, G.Y.P., Kelly, P.T. Cellular and molecular bases of memory: Synaptic and neuronal plasticity. J Clin Neurophysiol 1997, 14 (4): 264-93.
2. Eichenbaum, H. The hippocampus and mechanism of declarative memory. Behav Brain Res 1999, 103: 123-33.
3. Misner, D.L., Sullivan, J.M. Mechanism of cannabinoid effects on long-term potentiation and depression in hippocampal CA1 neuron. J Neurosci 1999, 19(16): 6795-805.
4. Shaprine, M.L., Eichenbaum, H. Hippocampus is a memory map: Synaptic plasticity and memory encoding by hippocampus neuron. Hippocampus 1999, 9: 365-84.
5. O'Malley, A., O'Connel, C., Murphy, K.J., Regan, C.M. Transient spine density increase in the mild-molecular layer of hippocampus dentate gyrus accompany consolidation of a spatial learning task in the rodent. Neuroscience 2000, 99(2): 229-32.
6. Teather, L.A., Packard, M.G., Bazan, N.G. Differential interaction of platelet-activating factor and NMDA receptor function in hippocampal and dorsal striatal memory processes. Neurobiol Learn Mem 2001, 75(3): 310-24.
7. Rioult-Pedotti, M.S., Friedman, D., Donoghue, J.P. Learning induced LTP in neocortex. Science 2000, 290: 533-6.
8. Maren, S. Long-term potentiation in the amygdala: A mechanism for emotional learning and memory. TINS 1992, 22(12): 561-6.
9. Prats-Vinas, J.M. Does the cerebellum play a part in cognitive processes? Rev Neurol 2000, 31(4): 357-9.
10. Bernstein, D. A., Clarke-Steward, A., Roy, E.J., Skull, T.K., Wickens, C.D. (Eds.). Memory. In: Psychology, 3rd Ed. Houghton-Mifflin Co.: Boston/Toronto 1994, 286-321.
11. Nader, K., Schafe, G.E., LeDoux, J.E. The labile nature of consolidation theory. Nat Rev Neurosci 2000, 1: 216-9.
12. McClelland, J.L., Goddard, N.H. Consolidation arising from a complementary learning system perspective on hippocampus and neocortex. Hippocampus 1996, 6: 654-65.
13. Bliss, T.V.P., Collingridge G.L. A synaptic model of memory: Long term potentiation in the hippocampus. Nature, 1993, 361: 31-9.
14. Hebb, D.O. The Organization of Behavior. Wiley: New York 1949.
15. Kandel, E.R., Howkins, R.D. The biological basis of learning and individuality. Sci Am 1992, 267(3): 79-86.
16. Bliss, T.V.P., Gardner-Medwin, A.R. Long lasting potentiation of synaptic transmission in the dentate area of unanesthetized rabbit following stimulation of the perforant path. J Physiol 1973, 232: 357-74.
17. McEachern, J.C., Shaw, C.A. The plasticity-pathology continuum: Defining a role for the LTP phenomenon. J Neurosci Res 1999, 58(1): 42-61.
18. Izquierdo, I. Long-term potentiation and mechanism of memory. Drug Dev Res 1993, 30: 1-17.
19. Izquierdo, I. Pharmacological evidences for a role of a long term potentiation in memory. FASEB J 1994, 8: 1139-45.
20. Izquierdo, I., Medina, J.H. Correlation between pharmacology of long term potentiation and pharmacology of memory. Neurobiol Learn Mem 1995, 63: 18-32.
21. Shors, T.J., Matzel, L.D. Long term potentiation: What's learning got to do with it? Behav Brain Sci 1997, 20: 597-655.
22. Staubi, U., Roger, G., Lynch, G. Facilitation of glutamate receptor enhances memory. Proc Natl Acad Sci USA 1994, 91: 777-81.
23. ++/calmodulin dependent protein protein kinase II activity and AMPA Glu R I subunit immunoreactivity. Eur J Neurosci 1998, 10: 266-76.
24. Sansom, C. Modulating AMPA receptors: Key to mild cognitive impairment and memory? Drug Discov Today 2000, 5(10): 441-2.
25. Xu, X., Boshoven, W., Curnn, D. NMDA receptor antagonist MK-801 and nitric oxide synthase inhibitor L-NAME do not produce state-dependent learning in goldfish. Psychology 1999, 27(3): 426-31.
26. Brun, V.H., Ytterbu, K., Morris, R.G.M., Moser, M.B., Moser, E. Retrograde amnesia for spatial memory induced by NMDA receptor-mediated long term potentiation. J Neurosci 2001, 21(1): 356-62.
27. Riedel, G., Reymann, K.G. Metabotropicglutamate receptors in hippocampus long term potentiation and learning and memory. Acta Physiol Scand 1996, 157: 1-19.
28. Thomas, R.S., Victor, A.D. Postsynaptic protein phosphorylation and LTP. TINS 2000, 23: 75-80.
29. Lishman, J. The CaM kinasell hypothesis for the storage of synaptic memory. TINS 1994, 17(10): 406-26.
30. Feldman, S., Meyer, J.S., Quenzer, L.F. (Eds.). The amino acid neurotransmitters and histamine. In: Principle of Neuropsychopharmacology. Sinauer Association Inc.: Sunderland 1997, 412-6.
31. Yamadia, K., Noda, Y., Nakayama, S. et al. Role of nitric oxide in learning and memory and in monoamine metabolism in the rat brain. Br J Pharmacol 1995, 115: 852-8.
32. Verma, A., Wirsch, D.I., Glatt, C.E., Ronnet, G.V., Synder, S.H. Carbon monooxide: A putative neuronal messenger. Science 1993, 259: 381-4.
33. Arai, A., Lynch, G. Factors regulating the magnitude of long term potentiation induced by theta pattern stimulation. Brain Res 1992, 598: 173-84.
34. Nishizaki, T., Nomura, T., Matsuoku, T., Tsujishita, Y. Arachidonic acid as a messenger for the expression of long-term potentiation. Biochem Biophys Res Commun 1999, 254: 446-9.
35. Kornecki, E., Wieraszko, A., Li, G. Pzapatzu, P., Ehrlich, Y.H. Platelet-activating factor (PAF) released during hippocampus LTP: Role as a retrograde messenger. Soc Neurosci Abst 1994, 24: 1515.
36. Medina, J.H., Izquierdo, I. Retrograde messenger, long term potentiation and memory. Brain Res Brain Res Rev 1995, 21(2): 185-94.
37. Kornecki, E., Wieraszko, A., Chan, J., Ehrlich, Y.H. Platelet activating factor (PAF) in memory formation: Role as a retrograde messenger in long-term potentiation. J Lipid Mediat Cell Signal 1996, 14: 115-26.
38. Golski, S., Olds, J.L., Mishkin, M., Olton, D.S., Alkon, D.L. Protein kinase C in the hippocampus is altered by spatial but not cued discrimination: A component task analysis. Brain Res 1995, 676: 53-62.
39. Fukunaga, K., Miyamoto, E. Current studies on a working model of CaM kinase II in hippocampus long term potentiation and memory. Jpn J Pharmacol 1999, 79: 7-15.
40. Orban, P.C., Chapman, P.F., Brambilla, R. Is the Ras-MAPK signalling pathway necessary for long term memory formation? TINS 1999, 22(1): 38-43.
41. Davis, S., Vanboutte, P., Pages, C., Caboche, J., Laroche, S. The MAPK/ERK cascade targets both EIK1 and cAMP response element-binding protein to control long-term potentiation dependent gene expression in the dentate gyrus in vivo. J Neurosci 2000, 20(12): 4563-72.
42. Anderson, P. Spine to remember. Nature 1999, 399: 19-21.
43. Muller, D., Toni, N., Buchs, P.A. Spine changes associated with long-term potentiation. Hippocampus 2000, 10: 596-604.
44. Henson, P.M., Cochrane, C.G. Acute immune complex disease in rabbits. The role of complement and of a leukocyte-dependent release of vasoactive amines from platelets. J Exp Med 1971, 133(3): 554-71.
45. Benveniste, J., Henson, P.M., Cochrane, C.G. Leukocyte-dependent histamine release from rabbit platelets: The role of IgE, basophils, and a platelet-activating factor. J Exp Med 1972, 136(6): 1356-77.
46. Muirhead E.E. Case fora renomedullary blood pressure lowering hormone. Contrib Nephrol 1978, 12: 69-81.
47. Demopoulos, C.A., Pinkard, R.N., Hanaban, D.J. Evidence of 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphocholine as the active component (a new class of lipid mediators). J Biol Chem, 1979, 254: 9355-8.
48. Hanaban, D.J., Demopoulous, C.A., Liehr, J., Pinckard, R.N. Identification of platelet activating factor isolated from rabbit basophils as acetyl glyceryl ether phosphocholine. J Biol Chem 1980, 255: 5514-6.
49. Polonsky, J., Tence, M., Varenne, P., Das, B.C., Lunel, J., Benveniste J. Release of 1-O-alkylglyceryl 3-phosphorylcholine, O-deacetyl platelet-activating factor, from leukocytes: Chemical ionization mass spectrometry of phospholipids. Proc Natl Acad Sci USA 1980, 77(12): 7019-23.
50. Lynch J.M., Lotner, G.Z., Betz, S.J., Henson, P.M. The release of a platelet-activating factor by stimulated rabbit neutrophils. J Immunol 1979, 123: 1219-26.
51. Sanchez-Crespo, M., Alonso, F., Egido, J. PAF in anaphylaxis and phagocytosis. I. Release from human peripheral polymorphonuclears and monocytes during the stimulation of ionophore A 23187 and phagocytosis but not from degranulating basophils. Immunology 1980, 40: 645-55.
52. 2 and release of arachidonic acid and other lipid mediator at the synapse: The role of platelet activating factor. J Lipid Mediat 1993, 6(1-3): 412-7.
53. Bazan, N.G., Allan, G. Platelet-activating factor in the modulation of excitatory amino acid neurotransmitter release and of gene expression. J Lipid Mediat Cell Signal 1996, 14(1-3): 321-30.
54. Bosch, V.D. Intracellular phospholipase A. Biochem Biophys Acta 1980, 604: 191-246.
55. Gomez-Cambronero, J., Inarrea, P., Alonso, F., Sanchez-Crespo, M. The role of calcium ions in the process of acetyl transferase activation during the formation of PAF acether. J Biochem 1984, 219: 419-24.
56. Farr, R.S., Wardlaw, M.L., Cox, C.P., Meng, K.E., Greene, D. Human serum acid-labile factor in an acyl-hydrolase that inactivates PAF. Fed Proc 1983, 42: 3120-2.
57. Chilton, F.H., O'Flaherty J.T., Ellis, J.M., Swenden, C.L., Wykle, R.L. Metabolic fate of platelet activating factor in neutrophils. J Biol Chem 1983, 258: 6357-61.
58. Jerusalinsky, D., Fin, C., Quillfeldt, J.A. et al. Effect of antagonists of platelet-activating factor receptors on memory of inhibitory avoidance in rats. Behav Neurol Biol 1994, 62(1): 1-3.
59. ++ in hippocampal neurons. Neuron 1992, 9(2): 285-94.
60. Tokumura, A., Kamiyasu, K., Takauchi, K., Tsukatani, H. Evidence of various homologues and analogues of platelet activating factor in lipid extract of bovine brain. Biochem Biophys Res Commun 1987, 145: 415-25.
61. Tokumura, A., Yotsumoto, T., Hoshikawa, T., Tanaka, T., Tsukatani, H. Quantitative analysis of platelet-activating factor in rat brain. Life Sci 1992, 51: 303-6.
62. Morcheselli, V.L., Rossowska, J.J., Domingo, M.T., Braquet, P., Bazan, N.G. Distinct platelet activating factor binding sites in synaptic endings and an intracellular membrane of rat cerebral cortex. J Biol Chem 1990, 256: 9140-5.
63. Tiberghien, C., Laurent, L., Junier, M.P., Dray, F. A competitive receptor binding assay for platelet-activating factor (PAF): Quantification of PAF in rat brain. J Lipid 1991, 3(3): 249-66.
64. Bazan, N.G. The neuronal messenger platelet-activating factor in plasticity and neurodegeneration. Prog Brain Res 1998, 118: 281-91.
65. Wieraszko, A., Kornecki, E., Hogan, M.V., Ehrlich, Y.H. Long-term potentiation in the hippocampus induced by platelet-activating factor. Neuron 1993, 10: 553-7.
66. Doucet, J.P., Bazan, N.G. Excitable membrane lipid messengers and immediate-early gene alteration of signal transmission in neuromodulations and neurotrauma. Mol Neurobiol 1992, 6(4): 1407-24.
67. Bazan, N.G., Rodriguez, D., Turco, E.B., Allan, G. Mediator in injury in neurotrauma: Intracellular signal transmission and gene expression. J Neurotrauma 1995, 12(5): 791-814.
68. Bazan, N.G. Bioactive lipids and gene expression in neuronal plasticity. Adv Exp Med Biol 1998, 446: 37-49.
69. Jerusalinsky, D.C., Fin, C., Quillfeldt, J.A. et al. Effect of antagonists of platelet activating factor receptors on memory of inhibitory avoidance in rats. Behav Neurol Biol 1994, 62: 1-3.
70. Bazan, N.G., Packard, M.G., Teather, L., Allan, G. Bioactive lipids in excitatory neutrotransmission and neuronal plasticity. Neurochem Int 1997, 30(2): 225-31.
71. Nishida, K., Markey, S.P., Kustova, Y., Morse, H.C., Skolinck, P., Basile, A. Increased brain levels of platelet activating factor in a murine acquired immune deficiency syndrome are NMDA-receptor mediated. J Neurochem 1996, 66(1): 433-5.
72. Schifitto, G., Sacktor, N., Marder, K. et al. Randomized trial of the platelet-activating factor antagonist lexipafant in HIV-assodated cognitive impairment. Neurological AIDS Research Consortium. Neurology 1999, 53(2): 391-6.
73. Smith, P.R., Layne, W.R. A comparison of lethal effects of nitrite and hydroxylamine in the mouse. J Pharmacol Exp Ther 1969, 165: 30-5.
74. Nathan, P. Can the cognitive enhancing effects of Ginkgo biloba be explained by its pharmacology? Med Hypotheses 2000, 55(6): 491-3.
75. Soholm, B. Clinical improvement of memory and other cognitive functions by Ginkgo biloba: Review of relevant literature. Adv Ther 1998, 15(1): 54-65.
76. Horr, R., Kieser, M. Ginkgo biloba special extract EGb 761 -An anti-dementia drug. Fortschr Med 1998, 116(3): 39-40.
77. Akisu, M., Kultursay, N., Coker, I., Huseyinov, A. Platelet-activating factor is an important mediator in hypoxic ischemic brain injury in the newborn rat. Flunarizine and Ginkgo biloba extract reduce PAF concentration in the brain. Biol Neonate 1998, 74(6): 439-44.
78. Clark, G.D., Happel, L.T., Zorunski, C.F., Bazan N.G. Enhancement of hippocampal excitatory synaptic transmission by platelet-activating factor. Neuro 1992,9(6): 1211-6.
79. Kato, K., Clark, J.D., Bazan, N.G., Zorumski, C.F. PAF as a potential retrograde messenger in CA1 hippocampal long-term potentiation. Nature 1994, 637: 175-9.
80. Kato, K., Zorumski, C.F. Platelet activaing factors (PAF) as a retrograde messenger. J Lipid Medial Cell Signal 1996, 147(1-3): 341-8.
81. Campbell, W.B., Halushka, P.V. Lipid-derived autacoids: Eicosanoids and Platelet activating factor. In: Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th Ed. Hardman, J.G., Limbird, L.E., Malinoff, P.B., Ruddon, R.W., Gilman, A.G. (Eds.). McGraw-Hill: New York, 1996, 610-4.
82. Izquierdo, I., Fin, C., Schmitz, P.K. et al. Memory enhancement by intrahippocampal, intra-amygdala or intra-entorhinal infusion of platelet-activating factor measured in an inhibitory avoidance task. Proc Natl Acad Sci USA 1995, 92: 5047-51.
83. Chen, C., Magee, J.C., Marcheselli, V., Hardy, M., Bazan, N.G. Attenuation of LTP in hippocampus dentate gyrus of mice deficient in the PAF receptor. J Neurophysiol 2001, 85(1): 384-90.
84. Fransescangelli, E., Boila, A., Goracci, G. Properties and regulation of microsomal PAF-synthesis enzymes in rat brain cortex. Neurochem Res 2000, 25(5): 705-13.
85. Suresh, P.S., Thomas, K.M., Sharma, A., Singh, M. Effect of PAF on various experimental model of amnesia. 38th Annu Conf Ind Pharmacol Soc (Dec 28-30, Gandhinagar) 2000, Abst NOP-12: 113.
86. Miyaura, S., Eguchi, H., Johnston, J.M. Effect of a cigarette smoke extract on the metabolism of the proinflammatory autacoid, platelet-activating factor. Circ Res 1992, 70(2): 341-7.
87. Saraf, M.K., Sharma, A., Singh, M. Possible involvement of PAF in neurobiology of learning and memory. 38th Annu Conf Ind Pharmacol Soc (Dec 28-30, Gandhinagar) 2000, Abst NOP-13: 114.
88. Teather, L.A., Packard, M.G., Bazan, N.G. Effects of post-training intrahippocampal injections of platelet-activating factor and PAF antagonists on memory. Neurobiol Learn Mem 1998, 70(3): 349-63.
89. Packard, M.G., Teather, L.A., Bazan, N.G. Effects of intrastriatal injections of platelet-activating factor and the PAF antagonist BN 52021 on memory. Neurobiol Learn Mem 1996, 66(2): 176-82.
90. Singh, N., Sharma, A., Singh, M. Effect of BN-50730 (PAF receptor antagonist) and physostigmine (AchE inhibitor) on learning and memory in mice. Meth Find Exp Clin Pharmacol 1997, 19: 585-8.
91. Singh, N., Sharma, A., Singh, M. Possible mechanism of alprazolam-induced amnesia in mice. Pharmacology 1998, 56: 46-50.
92. Kishore, K. Possible involvement of PAF in neurobiology of learning and memory in mice. Thesis-1998, Punjabi University, Patiala.